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Volumn 21, Issue 22, 2013, Pages 6929-6936

Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties

(4) Ceruso, Mariangela a Vullo, Daniela a Scozzafava, Andrea a Supuran, Claudiu T a

a UNIVERSITY OF FLORENCE (Italy)

Author keywords

1,3,5 Triazine; Carbonic anhydrase; Isoform selective inhibitor; Sulfonamide

Indexed keywords

4 (4' FLUORO 6' METHYLAMINO 1',3',5' TRIAZIN 2' YLAMINO)BENZENESULFONAMIDE; 4 (4',6' DIFLUORO 1',3',5' TRIAZIN 2' YLAMINO)BENZENESULFONAMIDE; 4 [4' FLUORO 6' (2'' HYDROXYETHYLAMINO) 1',3',5' TRIAZIN 2' YLAMINO]BENZENESULFONAMIDE; 4 [6 (4',6' DIFLUORO 1',3',5' TRIAZIN 2 YLAMINO)ETHYL]BENZENESULFONAMIDE; ACETAZOLAMIDE; AMINE; AMINO ACID; AMINOALCOHOL; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE III; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IV; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE V; CARBONATE DEHYDRATASE VI; CARBONATE DEHYDRATASE VII; CARBONATE DEHYDRATASE VIII; CARBONATE DEHYDRATASE X; CARBONATE DEHYDRATASE XI; CARBONATE DEHYDRATASE XII; CARBONATE DEHYDRATASE XIII; CARBONATE DEHYDRATASE XIV; ESTER DERIVATIVE; FLUORINE; METHYL 2'' [4' FLUORO 6' (4 SULFAMOYLPHENYLETHYLAMINO) 1',3',5' TRIAZIN 2' YLAMINO]ACETATE; SULFONAMIDE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION;

1,3,5-TRIAZINE; CARBONIC ANHYDRASE; ISOFORM-SELECTIVE INHIBITOR; SULFONAMIDE;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE INHIBITORS; ENZYME ACTIVATION; FLUORINE; HUMANS; ISOENZYMES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; SULFANILAMIDES; TRIAZINES;

EID: 84885844538 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.09.031 Document Type: Article

Times cited : (20)

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