High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 65, Issue 10, 2009, Pages 992-995

  Sippel, Katherine H ^a   Robbins, Arthur H ^a   Domsic, John ^a   Genis, Caroli ^a   Agbandje Mckenna, Mavis ^a   McKenna, Robert ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Acetazolamide; Human carbonic anhydrase II; Inhibitor design

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; GLYCEROL;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; ENZYME ACTIVE SITE; HUMAN;

ACETAZOLAMIDE; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CATALYTIC DOMAIN; DRUG DESIGN; GLYCEROL; HUMANS; MODELS, MOLECULAR;

EID: 70350336111     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309109036665     Document Type: Article

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