Carbonic anhydrase inhibitors: Cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 23, 2007, Pages 7229-7236

  Nishimori, Isao ^a   Minakuchi, Tomoko ^a   Onishi, Saburo ^a   Vullo, Daniela ^b   Cecchi, Alessandro ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Isozyme I, II, III; Prontosil; Sulfamate; Sulfonamide

Indexed keywords

4 AMINO 6 CHLORO BENZENE 1,3 DISULFONAMIDE; ACETAZOLAMIDE; ANTICONVULSIVE AGENT; ANTIGLAUCOMA AGENT; ANTINEOPLASTIC AGENT; BENZOLAMIDE; BRINZOLAMIDE; CARBON DIOXIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE III; CARBONATE DEHYDRATASE INHIBITOR; CELECOXIB; CYTOSOL RECEPTOR; DORZOLAMIDE; ENZYME INHIBITOR; ETHOXZOLAMIDE; INDISULAM; ISOENZYME; METHAZOLAMIDE; NEUROLEPTIC AGENT; SULFAMIDOCHRYSOIDINE; SULFANILAMIDE DERIVATIVE; SULFONAMIDE; SULPIRIDE; TOPIRAMATE; UNCLASSIFIED DRUG; VALDECOXIB; ZONISAMIDE;

ARTICLE; CATALYST; CLONING; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INACTIVATION; ENZYME PURIFICATION; GENETIC TRAIT; HUMAN; KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

AMINO ACID SEQUENCE; CARBONIC ANHYDRASE III; CARBONIC ANHYDRASE INHIBITORS; CLONING, MOLECULAR; CYTOSOL; ENZYME ACTIVATION; HUMANS; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; SULFONIC ACIDS;

EID: 35148870672     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.08.037     Document Type: Article

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