-
1
-
-
84862835653
-
Leptin, leptin gene and leptin receptor gene polymorphism in heart failure with preserved ejection fraction
-
doi:10.1007/s00380-011-0152-2. PMID:21584748
-
Abd El-Aziz, T.A., Mohamed, R.H., Mohamed, R.H., and Pasha, H.F. 2012. Leptin, leptin gene and leptin receptor gene polymorphism in heart failure with preserved ejection fraction. Heart Vessels, 27: 271-279. doi:10.1007/s00380-011-0152-2. PMID:21584748.
-
(2012)
Heart Vessels
, vol.27
, pp. 271-279
-
-
Abd El-Aziz, T.A.1
Mohamed, R.H.2
Mohamed, R.H.3
Pasha, H.F.4
-
2
-
-
34250891864
-
Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation
-
doi:10.1152/ajpheart.00579.2006. PMID:17220191
-
Abe, Y., Ono, K., Kawamura, T., Wada, H., Kita, T., Shimatsu, A., et al. 2007. Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation. Am. J. Physiol. Heart Circ. Physiol. 292: H2387-H2396. doi:10.1152/ajpheart.00579.2006. PMID:17220191.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
-
-
Abe, Y.1
Ono, K.2
Kawamura, T.3
Wada, H.4
Kita, T.5
Shimatsu, A.6
-
3
-
-
2442670123
-
Leptin signaling
-
doi:10.1016/j.physbeh.2004.02.014. PMID:15159169
-
Ahima, R.S., and Osei, S.Y. 2004. Leptin signaling. Physiol. Behav. 81: 223-241. doi:10.1016/j.physbeh.2004.02.014. PMID:15159169.
-
(2004)
Physiol. Behav.
, vol.81
, pp. 223-241
-
-
Ahima, R.S.1
Osei, S.Y.2
-
4
-
-
77955514503
-
Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor
-
doi:10.1016/j.bbalip.2010. 06.009. PMID:20601111
-
Akasaka, Y., Tsunoda, M., Ogata, T., Ide, T., and Murakami, K. 2010. Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor. Biochim. Biophys. Acta, 1801: 1115-1122. doi:10.1016/j.bbalip.2010. 06.009. PMID:20601111.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 1115-1122
-
-
Akasaka, Y.1
Tsunoda, M.2
Ogata, T.3
Ide, T.4
Murakami, K.5
-
5
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
doi:10.1006/bbrc.1999.0255. PMID:10092513
-
Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J., et al. 1999. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257: 79-83. doi:10.1006/bbrc.1999.0255. PMID:10092513.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
-
6
-
-
0042018759
-
Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice
-
doi:10.1161/01.CIR.0000083716.82622.FD. PMID:12885755
-
Barouch, L.A., Berkowitz, D.E., Harrison, R.W., O'Donnell, C.P., and Hare, J.M. 2003. Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. Circulation, 108: 754-759. doi:10.1161/01.CIR.0000083716.82622.FD. PMID:12885755.
-
(2003)
Circulation
, vol.108
, pp. 754-759
-
-
Barouch, L.A.1
Berkowitz, D.E.2
Harrison, R.W.3
O'Donnell, C.P.4
Hare, J.M.5
-
7
-
-
0037409319
-
Obesityassociated activation of angiotensin and endothelin in the cardiovascular system
-
doi:10.1016/S1357-2725(02) 00307-2. PMID:12676169
-
Barton, M., Carmona, R., Ortmann, J., Krieger, J.E., and Traupe, T. 2003. Obesityassociated activation of angiotensin and endothelin in the cardiovascular system. Int. J. Biochem. Cell Biol. 35: 826-837. doi:10.1016/S1357-2725(02) 00307-2. PMID:12676169.
-
(2003)
Int. J. Biochem. Cell Biol.
, vol.35
, pp. 826-837
-
-
Barton, M.1
Carmona, R.2
Ortmann, J.3
Krieger, J.E.4
Traupe, T.5
-
8
-
-
0031436148
-
Divergent signaling capacities of the long and short isoforms of the leptin receptor
-
doi:10.1074/jbc.272.51.32686. PMID:9405487
-
Bjorbaek, C., Uotani, S., da Silva, B., and Flier, J.S. 1997. Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 272: 32686-32695. doi:10.1074/jbc.272.51.32686. PMID:9405487.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32686-32695
-
-
Bjorbaek, C.1
Uotani, S.2
da Silva, B.3
Flier, J.S.4
-
9
-
-
80054986453
-
Obesity, leptin, and incident heart failure
-
doi:10.1016/j.jacc.2011.07.030. PMID:22018298
-
Deswal, A. 2011. Obesity, leptin, and incident heart failure. J. Am. Coll. Cardiol. 58: 1878-1880. doi:10.1016/j.jacc.2011.07.030. PMID:22018298.
-
(2011)
J. Am. Coll. Cardiol.
, vol.58
, pp. 1878-1880
-
-
Deswal, A.1
-
10
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
doi:10.1038/ng2048. PMID:17496892
-
Dina, C., Meyre, D., Gallina, S., Durand, E., Korner, A., Jacobson, P., et al. 2007. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet. 39: 724-726. doi:10.1038/ng2048. PMID:17496892.
-
(2007)
Nat. Genet.
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
-
11
-
-
0036230154
-
Insulin resistance in moderate chronic heart failure is related to hyperleptinaemia, but not to norepinephrine or TNF-alpha
-
doi:10.1016/S0167-5273(02)00022-0. PMID:11959387
-
Doehner, W., Rauchhaus, M., Godsland, I.F., Egerer, K., Niebauer, J., Sharma, R., et al. 2002. Insulin resistance in moderate chronic heart failure is related to hyperleptinaemia, but not to norepinephrine or TNF-alpha. Int. J. Cardiol. 83: 73-81. doi:10.1016/S0167-5273(02)00022-0. PMID:11959387.
-
(2002)
Int. J. Cardiol.
, vol.83
, pp. 73-81
-
-
Doehner, W.1
Rauchhaus, M.2
Godsland, I.F.3
Egerer, K.4
Niebauer, J.5
Sharma, R.6
-
12
-
-
0033709707
-
Leptin serum levels in cachectic heart failure patients. Relationship with tumor necrosis factor-α system
-
doi:10.1016/S0167-5273(00)00397-1. PMID:11104865
-
Filippatos, G.S., Tsilias, K., Venetsanou, K., Karambinos, E., Manolatos, D., Kranidis, A., et al. 2000. Leptin serum levels in cachectic heart failure patients. Relationship with tumor necrosis factor-α system. Int. J. Cardiol. 76: 117-122. doi:10.1016/S0167-5273(00)00397-1. PMID:11104865.
-
(2000)
Int. J. Cardiol.
, vol.76
, pp. 117-122
-
-
Filippatos, G.S.1
Tsilias, K.2
Venetsanou, K.3
Karambinos, E.4
Manolatos, D.5
Kranidis, A.6
-
13
-
-
67349211789
-
Inactivation of the Fto gene protects from obesity
-
doi:10.1038/nature07848. PMID:19234441
-
Fischer, J., Koch, L., Emmerling, C., Vierkotten, J., Peters, T., Bruning, J.C., and Ruther, U. 2009. Inactivation of the Fto gene protects from obesity. Nature, 458: 894-898. doi:10.1038/nature07848. PMID:19234441.
-
(2009)
Nature
, vol.458
, pp. 894-898
-
-
Fischer, J.1
Koch, L.2
Emmerling, C.3
Vierkotten, J.4
Peters, T.5
Bruning, J.C.6
Ruther, U.7
-
14
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
doi:10.1126/science.1141634. PMID:17434869
-
Frayling, T.M., Timpson, N.J., Weedon, M.N., Zeggini, E., Freathy, R.M., Lindgren, C.M., et al. 2007. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science, 316: 889-894. doi:10.1126/science.1141634. PMID:17434869.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
-
15
-
-
42249083837
-
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
doi:10.1210/en.2007-1457. PMID: 18218688
-
Fredriksson, R., Hagglund, M., Olszewski, P.K., Stephansson, O., Jacobsson, J.A., et al. 2008. The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology, 149: 2062-2071. doi:10.1210/en.2007-1457. PMID: 18218688.
-
(2008)
Endocrinology
, vol.149
, pp. 2062-2071
-
-
Fredriksson, R.1
Hagglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
-
16
-
-
84878089684
-
Role of leptin signaling in the pathogenesis of angiotensin II-mediated atrial fibrosis and fibrillation
-
doi:10.1161/CIRCEP.111.000104. PMID:23406575
-
Fukui, A., Takahashi, N., Nakada, C., Masaki, T., Kume, O., Shinohara, T., et al. 2013. Role of leptin signaling in the pathogenesis of angiotensin II-mediated atrial fibrosis and fibrillation. Circ. Arrhythm. Electrophysiol. 6: 402-409. doi:10.1161/CIRCEP.111.000104. PMID:23406575.
-
(2013)
Circ. Arrhythm. Electrophysiol.
, vol.6
, pp. 402-409
-
-
Fukui, A.1
Takahashi, N.2
Nakada, C.3
Masaki, T.4
Kume, O.5
Shinohara, T.6
-
17
-
-
84883394714
-
Identification of fat mass and obesity associated (FTO) protein expression in cardiomyocytes: Regulation by leptin and its contribution to leptininduced hypertrophy
-
[In press]
-
Gan, X.T., Zhao, G., Huang, C.X., Rowe, A.C., Purdham, D.M., and Karmazyn, M. 2013. Identification of fat mass and obesity associated (FTO) protein expression in cardiomyocytes: regulation by leptin and its contribution to leptininduced hypertrophy. PLoS One. [In press]
-
(2013)
PLoS One
-
-
Gan, X.T.1
Zhao, G.2
Huang, C.X.3
Rowe, A.C.4
Purdham, D.M.5
Karmazyn, M.6
-
18
-
-
0037195916
-
Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo
-
doi:10.1074/jbc.M205825200. PMID:12270921
-
Ge, H., Huang, L., Pourbahrami, T., and Li, C. 2002. Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo. J. Biol. Chem. 277: 45898-45903. doi:10.1074/jbc.M205825200. PMID:12270921.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45898-45903
-
-
Ge, H.1
Huang, L.2
Pourbahrami, T.3
Li, C.4
-
19
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
doi:10.1126/science. 1151710. PMID:17991826
-
Gerken, T., Girard, C.A., Tung, Y.C., Webby, C.J., Saudek, V., Hewitson, K.S., et al. 2007. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science, 318: 1469-1472. doi:10.1126/science. 1151710. PMID:17991826.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
-
20
-
-
67650588131
-
Newer biomarkers in heart failure
-
doi:10.1016/j.hfc.2009.04.004. PMID: 19631181
-
Gupta, S., Drazner, M.H., and de Lemos, J.A. 2009. Newer biomarkers in heart failure. Heart Fail. Clin. 5: 579-588. doi:10.1016/j.hfc.2009.04.004. PMID: 19631181.
-
(2009)
Heart Fail. Clin.
, vol.5
, pp. 579-588
-
-
Gupta, S.1
Drazner, M.H.2
de Lemos, J.A.3
-
21
-
-
1242270639
-
Leptin-induced signal transduction pathways
-
doi:10.1016/j.cellbi.2003.12. 003. PMID:14984741
-
Hegyi, K., Fulop, K., Kovacs, K., Toth, S., and Falus, A. 2004. Leptin-induced signal transduction pathways. Cell Biol. Int. 28: 159-169. doi:10.1016/j.cellbi.2003.12. 003. PMID:14984741.
-
(2004)
Cell Biol. Int.
, vol.28
, pp. 159-169
-
-
Hegyi, K.1
Fulop, K.2
Kovacs, K.3
Toth, S.4
Falus, A.5
-
22
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
doi:10. 1038/nrm1983. PMID:16936699
-
Heineke, J., and Molkentin, J.D. 2006. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 7: 589-600. doi:10. 1038/nrm1983. PMID:16936699.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
23
-
-
46749087463
-
Signalling mechanisms underlying the metabolic and other effects of adipokines on the heart
-
doi:10.1093/cvr/cvn115. PMID:18474523
-
Karmazyn, M., Purdham, D.M., Rapurohitam, V., and Zeidan, A. 2008. Signalling mechanisms underlying the metabolic and other effects of adipokines on the heart. Cardiovasc. Res. 79: 279-286. doi:10.1093/cvr/cvn115. PMID:18474523.
-
(2008)
Cardiovasc. Res.
, vol.79
, pp. 279-286
-
-
Karmazyn, M.1
Purdham, D.M.2
Rapurohitam, V.3
Zeidan, A.4
-
24
-
-
0038824160
-
The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction
-
doi:10.1136/heart.89.6.667. PMID:12748233
-
Kojima, S., Funahashi, T., Sakamoto, T., Miyamoto, S., Soejima, H., Hokamaki, J., et al. 2003. The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction. Heart, 89: 667. doi:10.1136/heart.89.6.667. PMID:12748233.
-
(2003)
Heart
, vol.89
, pp. 667
-
-
Kojima, S.1
Funahashi, T.2
Sakamoto, T.3
Miyamoto, S.4
Soejima, H.5
Hokamaki, J.6
-
25
-
-
84860909327
-
Intestinal microbiota determine severity of myocardial infarction in rats
-
doi:10.1096/fj.11-197921. PMID:22247331
-
Lam, V., Su, J., Koprowski, S., Hsu, A., Tweddell, J.S., Rafiee, P., et al. 2012. Intestinal microbiota determine severity of myocardial infarction in rats. FASEB J. 26: 1727-1735. doi:10.1096/fj.11-197921. PMID:22247331.
-
(2012)
FASEB J.
, vol.26
, pp. 1727-1735
-
-
Lam, V.1
Su, J.2
Koprowski, S.3
Hsu, A.4
Tweddell, J.S.5
Rafiee, P.6
-
26
-
-
79251638776
-
Where to go with FTO?
-
doi:10.1016/j.tem.2010.11.001. PMID:21131211
-
Larder, R., Cheung, M.K., Tung, Y.C., Yeo, G.S., and Coll, A.P. 2011. Where to go with FTO? Trends Endocrinol. Metab. 22: 53-59. doi:10.1016/j.tem.2010.11.001. PMID:21131211.
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 53-59
-
-
Larder, R.1
Cheung, M.K.2
Tung, Y.C.3
Yeo, G.S.4
Coll, A.P.5
-
27
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
doi:10.1038/379632a0. PMID:8628397
-
Lee, G.H., Proenca, R., Montez, J.M., Carroll, K.M., Darvishzadeh, J.G., Lee, J.I., et al. 1996. Abnormal splicing of the leptin receptor in diabetic mice. Nature, 379: 632-635. doi:10.1038/379632a0. PMID:8628397.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
-
28
-
-
65349152441
-
Plasma leptin levels and incidence of heart failure, cardiovascular disease, and total mortality in elderly individuals
-
doi:10.2337/dc08-1596. PMID:19114611
-
Lieb, W., Sullivan, L.M., Harris, T.B., Roubenoff, R., Benjamin, E.J., Levy, D., et al. 2009. Plasma leptin levels and incidence of heart failure, cardiovascular disease, and total mortality in elderly individuals. Diabetes Care, 32: 612-616. doi:10.2337/dc08-1596. PMID:19114611.
-
(2009)
Diabetes Care
, vol.32
, pp. 612-616
-
-
Lieb, W.1
Sullivan, L.M.2
Harris, T.B.3
Roubenoff, R.4
Benjamin, E.J.5
Levy, D.6
-
29
-
-
33646763902
-
Rho kinases in cardiovascular physiology and pathophysiology
-
doi:10.1161/01.RES. 0000201960.04223.3c. PMID:16484628
-
Loirand, G., Guerin, P., and Pacaud, P. 2006. Rho kinases in cardiovascular physiology and pathophysiology. Circ. Res. 98: 322-334. doi:10.1161/01.RES. 0000201960.04223.3c. PMID:16484628.
-
(2006)
Circ. Res.
, vol.98
, pp. 322-334
-
-
Loirand, G.1
Guerin, P.2
Pacaud, P.3
-
30
-
-
0031577546
-
Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues
-
doi:10.1006/bbrc.1997.7205. PMID:9299568
-
Lollmann, B., Gruninger, S., Stricker-Krongrad, A., and Chiesi, M. 1997. Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues. Biochem. Biophys. Res. Commun. 238: 648-652. doi:10.1006/bbrc.1997.7205. PMID:9299568.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 648-652
-
-
Lollmann, B.1
Gruninger, S.2
Stricker-Krongrad, A.3
Chiesi, M.4
-
31
-
-
0034801977
-
Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors
-
doi:10.1210/en.142.10.4389. PMID:11564702
-
Maamra, M., Bidlingmaier, M., Postel-Vinay, M.C., Wu, Z., Strasburger, C.J., and Ross, R.J. 2002. Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors. Endocrinology, 142: 4389-4393. doi:10.1210/en.142.10.4389. PMID:11564702.
-
(2002)
Endocrinology
, vol.142
, pp. 4389-4393
-
-
Maamra, M.1
Bidlingmaier, M.2
Postel-Vinay, M.C.3
Wu, Z.4
Strasburger, C.J.5
Ross, R.J.6
-
32
-
-
31344444358
-
Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes
-
doi:10.1016/j. cardiores.2005.11.022. PMID:16376323
-
Madani, S., De Girolamo, S., Munoz, D.M., Li, R.K., and Sweeney, G. 2006. Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes. Cardiovasc. Res. 69: 716-275. doi:10.1016/j. cardiores.2005.11.022. PMID:16376323.
-
(2006)
Cardiovasc. Res.
, vol.69
, pp. 275-716
-
-
Madani, S.1
De Girolamo, S.2
Munoz, D.M.3
Li, R.K.4
Sweeney, G.5
-
33
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
doi:10.1038/nm1195-1155. PMID:7584987
-
Maffei, M., Halaas, J., Ravussin, E., Pratley, R.E., Lee, G.H., Zhang, Y., et al. 1995. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1: 1155-1161. doi:10.1038/nm1195-1155. PMID:7584987.
-
(1995)
Nat. Med.
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
-
34
-
-
84864341714
-
The obesity-related peptide leptin sensitizes cardiac mitochondria to calcium-induced permeability transition pore opening and apoptosis
-
doi:10.1371/journal.pone.0041612. PMID:22848545
-
Martinez-Abundis, E., Rajapurohitam, V., Haist, J.V., Gan, X.T., and Karmazyn, M. 2012. The obesity-related peptide leptin sensitizes cardiac mitochondria to calcium-induced permeability transition pore opening and apoptosis. PLoS One, 7: e41612. doi:10.1371/journal.pone.0041612. PMID:22848545.
-
(2012)
PLoS One
, vol.7
-
-
Martinez-Abundis, E.1
Rajapurohitam, V.2
Haist, J.V.3
Gan, X.T.4
Karmazyn, M.5
-
35
-
-
84871598386
-
Pressure mediated hypertrophy and mechanical stretch upregulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes
-
doi:10.1186/1471-2121-13-37. PMID:23270329
-
Matsui, H., Yokoyama, T., Tanaka, C., Sunaga, H., Koitabashi, N., Takizawa, T., et al. 2012. Pressure mediated hypertrophy and mechanical stretch upregulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes. BMC Cell Biol. 13: 37. doi:10.1186/1471-2121-13-37. PMID:23270329.
-
(2012)
BMC Cell Biol.
, vol.13
, pp. 37
-
-
Matsui, H.1
Yokoyama, T.2
Tanaka, C.3
Sunaga, H.4
Koitabashi, N.5
Takizawa, T.6
-
36
-
-
78650504740
-
Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice
-
doi:10.1093/cvr/cvq288. PMID:20833647
-
McGaffin, K.R., Witham, W.G., Yester, K.A., Romano, L.C., O'Doherty, R.M., McTiernan, C.F., et al. 2011. Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice. Cardiovasc. Res. 89: 60-71. doi:10.1093/cvr/cvq288. PMID:20833647.
-
(2011)
Cardiovasc. Res.
, vol.89
, pp. 60-71
-
-
McGaffin, K.R.1
Witham, W.G.2
Yester, K.A.3
Romano, L.C.4
O'Doherty, R.M.5
McTiernan, C.F.6
-
37
-
-
81555204274
-
Ginseng (Panax quinquefolius) attenuates leptin-induced cardiac hypertrophy through inhibition of p115Rho guanine nucleotide exchange factor-RhoA/Rho-associated, coiled-coil containing protein kinase-dependent mitogen-activated protein kinase pathway activation
-
doi:10.1124/jpet.111.182600. PMID:21875949
-
Moey, M., Rajapurohitam, V., Zeidan, A., and Karmazyn, M. 2011. Ginseng (Panax quinquefolius) attenuates leptin-induced cardiac hypertrophy through inhibition of p115Rho guanine nucleotide exchange factor-RhoA/Rho-associated, coiled-coil containing protein kinase-dependent mitogen-activated protein kinase pathway activation. J. Pharmacol. Exp. Ther. 339: 746-756. doi:10.1124/jpet.111.182600. PMID:21875949.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.339
, pp. 746-756
-
-
Moey, M.1
Rajapurohitam, V.2
Zeidan, A.3
Karmazyn, M.4
-
38
-
-
79960308770
-
Inhibition of cardiac leptin expression after infarction reduces subsequent dysfunction
-
doi:10. 1111/j.1582-4934.2010.01154.x. PMID:20731748
-
Moro, C., Grauzam, S., Ormezzano, O., Toufektsian, M.C., Tanguy, S., Calabrese, P., et al. 2011. Inhibition of cardiac leptin expression after infarction reduces subsequent dysfunction. J. Cell. Mol. Med. 15: 1688-1694. doi:10. 1111/j.1582-4934.2010.01154.x. PMID:20731748.
-
(2011)
J. Cell. Mol. Med.
, vol.15
, pp. 1688-1694
-
-
Moro, C.1
Grauzam, S.2
Ormezzano, O.3
Toufektsian, M.C.4
Tanguy, S.5
Calabrese, P.6
-
39
-
-
0032846516
-
Inappropriately low plasma leptin concentration in the cachexia associated with chronic heart failure
-
doi:10. 1136/hrt.82.3.352. PMID:10455089
-
Murdoch, D.R., Rooney, E., Dargie, H.J., Shapiro, D., Morton, J.J., and McMurray, J.J. 1999. Inappropriately low plasma leptin concentration in the cachexia associated with chronic heart failure. Heart, 82: 352-356. doi:10. 1136/hrt.82.3.352. PMID:10455089.
-
(1999)
Heart
, vol.82
, pp. 352-356
-
-
Murdoch, D.R.1
Rooney, E.2
Dargie, H.J.3
Shapiro, D.4
Morton, J.J.5
McMurray, J.J.6
-
40
-
-
2342444310
-
Leptin receptor signaling and the regulation of mammalian physiology
-
PMID:14749507
-
Myers, M.G., Jr. 2004. Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog. Horm. Res. 59: 287-304. PMID:14749507.
-
(2004)
Recent Prog. Horm. Res.
, vol.59
, pp. 287-304
-
-
Myers Jr., M.G.1
-
41
-
-
11144354080
-
Implications of plasma concentrations of adiponectin in patients with coronary artery disease
-
doi:10.1136/hrt.2003.011114. PMID:15084551
-
Nakamura, Y., Shimada, K., Fukuda, D., Shimada, Y., Ehara, S., Hirose, M., et al. 2004. Implications of plasma concentrations of adiponectin in patients with coronary artery disease. Heart, 90: 528-533. doi:10.1136/hrt.2003.011114. PMID:15084551.
-
(2004)
Heart
, vol.90
, pp. 528-533
-
-
Nakamura, Y.1
Shimada, K.2
Fukuda, D.3
Shimada, Y.4
Ehara, S.5
Hirose, M.6
-
42
-
-
33645457715
-
Physiological role of ROCKs in the cardiovascular system
-
doi:10. 1152/ajpcell.00459.2005. PMID:16469861
-
Noma, K., Oyama, N., and Liao, J.K. 2006. Physiological role of ROCKs in the cardiovascular system. Am. J. Physiol. Cell Physiol. 290: C661-C668. doi:10. 1152/ajpcell.00459.2005. PMID:16469861.
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
-
-
Noma, K.1
Oyama, N.2
Liao, J.K.3
-
43
-
-
84864186352
-
Adipokines and the cardiovascular system: Mechanisms mediating health and disease
-
doi:10.1139/y2012-053. PMID:22646022
-
Northcott, J.M., Yeganeh, A., Taylor, C.G., Zahradka, P., and Wigle, J.T. 2012. Adipokines and the cardiovascular system: mechanisms mediating health and disease. Can. J. Physiol. Pharmacol. 90(8): 1029-1059. doi:10.1139/y2012-053. PMID:22646022.
-
(2012)
Can. J. Physiol. Pharmacol.
, vol.90
, Issue.8
, pp. 1029-1059
-
-
Northcott, J.M.1
Yeganeh, A.2
Taylor, C.G.3
Zahradka, P.4
Wigle, J.T.5
-
44
-
-
0347334429
-
Obesity, adiponectin and vascular inflammatory disease
-
doi:10.1097/00041433-200312000-00003. PMID:14624132
-
Ouchi, N., Kihara, S., Funahashi, T., Matsuzawa, Y., and Walsh, K. 2003. Obesity, adiponectin and vascular inflammatory disease. Curr. Opin. Lipidol. 14: 561-566. doi:10.1097/00041433-200312000-00003. PMID:14624132.
-
(2003)
Curr. Opin. Lipidol.
, vol.14
, pp. 561-566
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
Matsuzawa, Y.4
Walsh, K.5
-
45
-
-
84885329744
-
Direct effects of adipokines on the heart: Focus on adiponectin
-
In press. doi:10.1007/s10741-012-9337-8. PMID: 22893246
-
Park, M., and Sweeney, G. 2012. Direct effects of adipokines on the heart: focus on adiponectin. Heart Fail. In press. doi:10.1007/s10741-012-9337-8. PMID: 22893246.
-
(2012)
Heart Fail
-
-
Park, M.1
Sweeney, G.2
-
46
-
-
34848877481
-
Raised leptin concentrations among South Asian patients with chronic heart failure
-
doi:10.1016/j.ijcard.2006.11.013. PMID:17187880
-
Patel, J.V., Sosin, M., Lim, H.S., Chung, I., Panja, N., Davis, R.C., et al. 2007. Raised leptin concentrations among South Asian patients with chronic heart failure. Int. J. Cardiol. 122: 34-40. doi:10.1016/j.ijcard.2006.11.013. PMID:17187880.
-
(2007)
Int. J. Cardiol.
, vol.122
, pp. 34-40
-
-
Patel, J.V.1
Sosin, M.2
Lim, H.S.3
Chung, I.4
Panja, N.5
Davis, R.C.6
-
47
-
-
0032886705
-
Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation
-
doi:10.1007/s003359901144. PMID:10501967
-
Peters, T., Ausmeier, K., and Ruther, U. 1999. Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation. Mamm. Genome, 10: 983-986. doi:10.1007/s003359901144. PMID:10501967.
-
(1999)
Mamm. Genome
, vol.10
, pp. 983-986
-
-
Peters, T.1
Ausmeier, K.2
Ruther, U.3
-
48
-
-
9344248077
-
Rat heart is a site of leptin production and action
-
doi:10.1152/ajpheart.00499.2004. PMID:15284063
-
Purdham, D.M., Zou, M.X., Rajapurohitam, V., and Karmazyn, M. 2004. Rat heart is a site of leptin production and action. Am. J. Physiol. Heart Circ. Physiol. 287: H2877-H2884. doi:10.1152/ajpheart.00499.2004. PMID:15284063.
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
-
-
Purdham, D.M.1
Zou, M.X.2
Rajapurohitam, V.3
Karmazyn, M.4
-
49
-
-
49849103205
-
A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart
-
doi:10.1152/ajpheart.91537. 2007. PMID:18469142
-
Purdham, D.M., Rajapurohitam, V., Zeidan, A., Huang, C., Gross, G.J., and Karmazyn, M. 2008. A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart. Am. J. Physiol. Heart Circ. Physiol. 295: H441-H446. doi:10.1152/ajpheart.91537. 2007. PMID:18469142.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.295
-
-
Purdham, D.M.1
Rajapurohitam, V.2
Zeidan, A.3
Huang, C.4
Gross, G.J.5
Karmazyn, M.6
-
50
-
-
0041857804
-
The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes
-
doi:10.1161/01.RES.0000089255. 37804.72. PMID:12893740
-
Rajapurohitam, V., Gan, X.T., Kirshenbaum, L.A., and Karmazyn, M. 2003. The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. Circ. Res. 93: 277-279. doi:10.1161/01.RES.0000089255. 37804.72. PMID:12893740.
-
(2003)
Circ. Res.
, vol.93
, pp. 277-279
-
-
Rajapurohitam, V.1
Gan, X.T.2
Kirshenbaum, L.A.3
Karmazyn, M.4
-
51
-
-
33746093293
-
An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1
-
doi:10.1016/j.yjmcc.2006.05.001. PMID:16806260
-
Rajapurohitam, V., Javadov, S., Purdham, D.M., Kirshenbaum, L.A., and Karmazyn, M. 2006. An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1. J. Mol. Cell. Cardiol. 41: 265-274. doi:10.1016/j.yjmcc.2006.05.001. PMID:16806260.
-
(2006)
J. Mol. Cell. Cardiol.
, vol.41
, pp. 265-274
-
-
Rajapurohitam, V.1
Javadov, S.2
Purdham, D.M.3
Kirshenbaum, L.A.4
Karmazyn, M.5
-
52
-
-
84862016838
-
Role of NF-κB and p38 MAPK activation in mediating angiotensin II and endothelin-1-induced stimulation in leptin production and cardiomyocyte hypertrophy
-
doi:10.1007/s11010-012-1307-x. PMID: 22527934
-
Rajapurohitam, V., Kilic, A., Javadov, S., and Karmazyn, M. 2012a. Role of NF-κB and p38 MAPK activation in mediating angiotensin II and endothelin-1-induced stimulation in leptin production and cardiomyocyte hypertrophy. Mol. Cell. Biochem. 366: 287-297. doi:10.1007/s11010-012-1307-x. PMID: 22527934.
-
(2012)
Mol. Cell. Biochem.
, vol.366
, pp. 287-297
-
-
Rajapurohitam, V.1
Kilic, A.2
Javadov, S.3
Karmazyn, M.4
-
53
-
-
84865628637
-
Leptin-induced cardiomyocyte hypertrophy reveals both calciumdependent and calcium-independent/RhoA-dependent calcineurin activation and NFAT nuclear translocation
-
doi:10.1016/j.cellsig.2012.07.025. PMID:22917533
-
Rajapurohitam, V., Izaddoustdar, F., Martinez-Abundis, E., and Karmazyn, M. 2012b. Leptin-induced cardiomyocyte hypertrophy reveals both calciumdependent and calcium-independent/RhoA-dependent calcineurin activation and NFAT nuclear translocation. Cell. Signal. 24: 2283-2290. doi:10.1016/j.cellsig.2012.07.025. PMID:22917533.
-
(2012)
Cell. Signal.
, vol.24
, pp. 2283-2290
-
-
Rajapurohitam, V.1
Izaddoustdar, F.2
Martinez-Abundis, E.3
Karmazyn, M.4
-
54
-
-
77649342305
-
Molecular targets and regulators of cardiac hypertrophy
-
doi:10.1016/j.phrs.2009.11.012. PMID:19969085
-
Rohini, A., Agrawal, N., Koyani, C.N., and Singh, R. 2010. Molecular targets and regulators of cardiac hypertrophy. Pharmacol. Res. 61: 269-280. doi:10.1016/j.phrs.2009.11.012. PMID:19969085.
-
(2010)
Pharmacol. Res.
, vol.61
, pp. 269-280
-
-
Rohini, A.1
Agrawal, N.2
Koyani, C.N.3
Singh, R.4
-
55
-
-
33646873050
-
Adipocyte-derived hormones, cytokines, and mediators
-
doi:10.1385/ENDO:29:1:81. PMID:16622295
-
Rondinone, C.M. 2006. Adipocyte-derived hormones, cytokines, and mediators. Endocrine, 29: 81-90. doi:10.1385/ENDO:29:1:81. PMID:16622295.
-
(2006)
Endocrine
, vol.29
, pp. 81-90
-
-
Rondinone, C.M.1
-
56
-
-
33746745255
-
Adiponectin and coronary heart disease: A prospective study and meta-analysis
-
doi:10.1161/CIRCULATIONAHA.106. 618918. PMID:16894037
-
Sattar, N., Wannamethee, G., Sarwar, N., Tchernova, J., Cherry, L., Wallace, A.M., et al. 2006. Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation, 114: 623-629. doi:10.1161/CIRCULATIONAHA.106. 618918. PMID:16894037.
-
(2006)
Circulation
, vol.114
, pp. 623-629
-
-
Sattar, N.1
Wannamethee, G.2
Sarwar, N.3
Tchernova, J.4
Cherry, L.5
Wallace, A.M.6
-
57
-
-
42749090245
-
Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts
-
doi:10.1016/j.yjmcc.2008.03.005. PMID:18436234
-
Schram, K., Wong, M.M., Palanivel, R., No, E.K., Dixon, I.M., and Sweeney, G. 2008. Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts. J. Mol. Cell. Cardiol. 44: 874-878. doi:10.1016/j.yjmcc.2008.03.005. PMID:18436234.
-
(2008)
J. Mol. Cell. Cardiol.
, vol.44
, pp. 874-878
-
-
Schram, K.1
Wong, M.M.2
Palanivel, R.3
No, E.K.4
Dixon, I.M.5
Sweeney, G.6
-
58
-
-
27744536240
-
Leptin as a new diagnostic tool in chronic heart failure
-
doi:10.1016/j.cccn.2005.05.019. PMID:16005450
-
Schulze, P.C., and Kratzsch, J. 2005. Leptin as a new diagnostic tool in chronic heart failure. Clin. Chim. Acta, 362: 1-11. doi:10.1016/j.cccn.2005.05.019. PMID:16005450.
-
(2005)
Clin. Chim. Acta
, vol.362
, pp. 1-11
-
-
Schulze, P.C.1
Kratzsch, J.2
-
59
-
-
12244309089
-
Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure
-
doi:10.1016/S1388-9842(02)00177-0. PMID:12559213
-
Schulze, P.C., Kratzsch, J., Linke, A., Schoene, N., Adams, V., Gielen, S., et al. 2003. Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure. Eur. J. Heart Fail. 5: 33-40. doi:10.1016/S1388-9842(02)00177-0. PMID:12559213.
-
(2003)
Eur. J. Heart Fail.
, vol.5
, pp. 33-40
-
-
Schulze, P.C.1
Kratzsch, J.2
Linke, A.3
Schoene, N.4
Adams, V.5
Gielen, S.6
-
60
-
-
84855962337
-
Dynamics in insulin resistance and plasma levels of adipokines in patients with acute decompensated and chronic stable heart failure
-
doi:10.1016/j.cardfail.2011.08.010. PMID:22123363
-
Schulze, P.C., Biolo, A., Gopal, D., Shahzad, K., Balog, J., Fish, M., et al. 2011. Dynamics in insulin resistance and plasma levels of adipokines in patients with acute decompensated and chronic stable heart failure. J. Card. Fail. 17: 1004-1011. doi:10.1016/j.cardfail.2011.08.010. PMID:22123363.
-
(2011)
J. Card. Fail.
, vol.17
, pp. 1004-1011
-
-
Schulze, P.C.1
Biolo, A.2
Gopal, D.3
Shahzad, K.4
Balog, J.5
Fish, M.6
-
61
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
doi:10.1371/journal. pgen.0030115. PMID:17658951
-
Scuteri, A., Sanna, S., Chen, W.M., Uda, M., Albai, G., Strait, J., et al. 2007. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 3: e115. doi:10.1371/journal. pgen.0030115. PMID:17658951.
-
(2007)
PLoS Genet.
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
Strait, J.6
-
62
-
-
0007524724
-
Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting
-
doi:10.1172/JCI118913. PMID:8823291
-
Sinha, M.K., Opentanova, I., Ohannesian, J.P., Kolaczynski, J.W., Heiman, M.L., Hale, J., et al. 1996. Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting. J. Clin. Invest. 98: 1277-1282. doi:10.1172/JCI118913. PMID:8823291.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1277-1282
-
-
Sinha, M.K.1
Opentanova, I.2
Ohannesian, J.P.3
Kolaczynski, J.W.4
Heiman, M.L.5
Hale, J.6
-
63
-
-
78650109948
-
Leptin and inflammation in patients with chronic heart failure
-
PMID:21108202
-
Straburzyńska-Migaj, E., Gwizdała, A., Siniawski, A., Ochotny, R., and Grajek, S. 2010. Leptin and inflammation in patients with chronic heart failure. Kardiol. Pol. 68: 1243-1247. PMID:21108202.
-
(2010)
Kardiol. Pol.
, vol.68
, pp. 1243-1247
-
-
Straburzyńska-Migaj, E.1
Gwizdała, A.2
Siniawski, A.3
Ochotny, R.4
Grajek, S.5
-
64
-
-
1642464978
-
Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase-and phosphatidylinositol 3-kinase-dependent signaling pathways
-
doi:10.1210/en.2003-1128. PMID:14715711
-
Tajmir, P., Ceddia, R.B., Li, R.K., Coe, I.R., and Sweeney, G. 2004. Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase-and phosphatidylinositol 3-kinase-dependent signaling pathways. Endocrinology, 145: 1550-1555. doi:10.1210/en.2003-1128. PMID:14715711.
-
(2004)
Endocrinology
, vol.145
, pp. 1550-1555
-
-
Tajmir, P.1
Ceddia, R.B.2
Li, R.K.3
Coe, I.R.4
Sweeney, G.5
-
65
-
-
59249084502
-
Adiponectin is released from the heart in patients with heart failure
-
doi:10.1016/j.ijcard.2007.11.040. PMID:18192035
-
Takano, H., Obata, J.E., Kodama, Y., Kitta, Y., Nakamura, T., Mende, A., et al. 2009. Adiponectin is released from the heart in patients with heart failure. Int. J. Cardiol. 132: 221-226. doi:10.1016/j.ijcard.2007.11.040. PMID:18192035.
-
(2009)
Int. J. Cardiol.
, vol.132
, pp. 221-226
-
-
Takano, H.1
Obata, J.E.2
Kodama, Y.3
Kitta, Y.4
Nakamura, T.5
Mende, A.6
-
66
-
-
0030899777
-
Plasma leptin concentrations and energy expenditure in heart failure patients
-
doi:10.1016/S0026-0495(97)90065-2. PMID: 9109853
-
Toth, M.J., Gottlieb, S.S., Fisher, M.L., Ryan, A.S., Nicklas, B.J., and Poehlman, E.T. 1997. Plasma leptin concentrations and energy expenditure in heart failure patients. Metabolism, 46: 450-453. doi:10.1016/S0026-0495(97)90065-2. PMID: 9109853.
-
(1997)
Metabolism
, vol.46
, pp. 450-453
-
-
Toth, M.J.1
Gottlieb, S.S.2
Fisher, M.L.3
Ryan, A.S.4
Nicklas, B.J.5
Poehlman, E.T.6
-
67
-
-
79952474482
-
From GWAS to biology: Lessons from FTO
-
doi:10.1111/j.1749-6632.2010.05903.x. PMID: 21388413
-
Tung, Y.C., and Yeo, G.S. 2011. From GWAS to biology: lessons from FTO. Ann. N.Y. Acad. Sci. 1220: 162-171. doi:10.1111/j.1749-6632.2010.05903.x. PMID: 21388413.
-
(2011)
Ann. N.Y. Acad. Sci.
, vol.1220
, pp. 162-171
-
-
Tung, Y.C.1
Yeo, G.S.2
-
68
-
-
58149499180
-
Leptin receptor signaling and the regulation of mammalian physiology
-
doi:10.1038/ijo.2008.232. PMID:19136996
-
Villanueva, E.C., and Myers, M.G., Jr. 2008. Leptin receptor signaling and the regulation of mammalian physiology. Int. J. Obes. (Lond.), 32(Suppl. 7): S8-S12. doi:10.1038/ijo.2008.232. PMID:19136996.
-
(2008)
Int. J. Obes. (Lond.)
, vol.32
, Issue.SUPPL. 7
-
-
Villanueva, E.C.1
Myers Jr., M.G.2
-
69
-
-
79957945033
-
Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass-and obesity-associated (FTO) downregulation during energy restriction
-
doi:10.2119/molmed.2010.00134. PMID:21267512
-
Wang, P., Yang, F.J., Du, H., Guan, Y.F., Xu, T.Y., Xu, X.W., et al. 2011. Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass-and obesity-associated (FTO) downregulation during energy restriction. Mol. Med. 17: 523-532. doi:10.2119/molmed.2010.00134. PMID:21267512.
-
(2011)
Mol. Med.
, vol.17
, pp. 523-532
-
-
Wang, P.1
Yang, F.J.2
Du, H.3
Guan, Y.F.4
Xu, T.Y.5
Xu, X.W.6
-
70
-
-
80054968141
-
Obesity and risk of incident heart failure in older men with and without pre-existing coronary heart disease: Does leptin have a role?
-
doi:10.1016/j.jacc.2011.06.057. PMID:22018297
-
Wannamethee, S.G., Shaper, A.G., Whincup, P.H., Lennon, L., and Sattar, N. 2011. Obesity and risk of incident heart failure in older men with and without pre-existing coronary heart disease: does leptin have a role? J. Am. Coll. Cardiol. 58: 1870-1877. doi:10.1016/j.jacc.2011.06.057. PMID:22018297.
-
(2011)
J. Am. Coll. Cardiol.
, vol.58
, pp. 1870-1877
-
-
Wannamethee, S.G.1
Shaper, A.G.2
Whincup, P.H.3
Lennon, L.4
Sattar, N.5
-
71
-
-
0036157726
-
Abrogated leptininduced cardiac contractile response in ventricular myocytes under spontaneous hypertension: Role of Jak/STAT pathway
-
doi:10.1161/hy0102.100777. PMID:11799081
-
Wold, L.E., Relling, D.P., Duan, J., Norby, F.L., and Ren, J. 2002. Abrogated leptininduced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway. Hypertension, 39: 69-74. doi:10.1161/hy0102.100777. PMID:11799081.
-
(2002)
Hypertension
, vol.39
, pp. 69-74
-
-
Wold, L.E.1
Relling, D.P.2
Duan, J.3
Norby, F.L.4
Ren, J.5
-
72
-
-
4444303576
-
Leptin induces hypertrophy via endothelin-1-1reactive oxygen species pathway in cultured neonatal rat cardiomyocytes
-
doi:10. 1161/01.CIR.0000140766.52771.6D. PMID:15313952
-
Xu, F.P., Chen, M.S., Wang, Y.Z., Yi, Q., Lin, S.B., Chen, A.F., et al. 2004. Leptin induces hypertrophy via endothelin-1-1reactive oxygen species pathway in cultured neonatal rat cardiomyocytes. Circulation, 110: 1269-1275. doi:10. 1161/01.CIR.0000140766.52771.6D. PMID:15313952.
-
(2004)
Circulation
, vol.110
, pp. 1269-1275
-
-
Xu, F.P.1
Chen, M.S.2
Wang, Y.Z.3
Yi, Q.4
Lin, S.B.5
Chen, A.F.6
-
73
-
-
0037494960
-
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
-
doi:10.1038/nature01705. PMID:12802337
-
Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., et al. 2003. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature, 423: 762-769. doi:10.1038/nature01705. PMID:12802337.
-
(2003)
Nature
, vol.423
, pp. 762-769
-
-
Yamauchi, T.1
Kamon, J.2
Ito, Y.3
Tsuchida, A.4
Yokomizo, T.5
Kita, S.6
-
74
-
-
80055030403
-
Novel biomarkers in acute heart failure
-
doi:10.1007/s11897-011-0065-5. PMID: 21681444
-
Yanavitski, M., and Givertz, M.M. 2011. Novel biomarkers in acute heart failure. Curr. Heart Fail. Rep. 8: 206-211. doi:10.1007/s11897-011-0065-5. PMID: 21681444.
-
(2011)
Curr. Heart Fail. Rep.
, vol.8
, pp. 206-211
-
-
Yanavitski, M.1
Givertz, M.M.2
-
75
-
-
0037862102
-
The ins and outs of leptin receptor activation
-
doi:10.1016/S0014-5793(03)00440-X. PMID:12829235
-
Zabeau, L., Lavens, D., Peelman, F., Eyckerman, S., Vandekerckhove, J., and Tavernier, J. 2003. The ins and outs of leptin receptor activation. FEBS Lett. 546: 45-50. doi:10.1016/S0014-5793(03)00440-X. PMID:12829235.
-
(2003)
FEBS Lett.
, vol.546
, pp. 45-50
-
-
Zabeau, L.1
Lavens, D.2
Peelman, F.3
Eyckerman, S.4
Vandekerckhove, J.5
Tavernier, J.6
-
76
-
-
33748130863
-
Essential role of Rho/ROCKdependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes
-
doi:10.1016/j.cardiores.2006.06.024. PMID:16901475
-
Zeidan, A., Javadov, S., and Karmazyn, M. 2006. Essential role of Rho/ROCKdependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes. Cardiovasc. Res. 72: 101-111. doi:10.1016/j.cardiores.2006.06.024. PMID:16901475.
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 101-111
-
-
Zeidan, A.1
Javadov, S.2
Karmazyn, M.3
-
77
-
-
38849188633
-
Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCKdependent p38 MAPK translocation to nuclei
-
doi:10.1093/cvr/cvm020. PMID:18006472
-
Zeidan, A., Javadov, S., Chakrabarti, S., and Karmazyn, M. 2008. Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCKdependent p38 MAPK translocation to nuclei. Cardiovasc. Res. 77: 64-72. doi:10.1093/cvr/cvm020. PMID:18006472.
-
(2008)
Cardiovasc. Res.
, vol.77
, pp. 64-72
-
-
Zeidan, A.1
Javadov, S.2
Chakrabarti, S.3
Karmazyn, M.4
-
78
-
-
79959211157
-
mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy
-
doi:10.1007/s11010-011-0744-2. PMID:21318349
-
Zeidan, A., Hunter, J.C., Javadov, S., and Karmazyn, M. 2011. mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy. Mol. Cell. Biochem. 352: 99-108. doi:10.1007/s11010-011-0744-2. PMID:21318349.
-
(2011)
Mol. Cell. Biochem.
, vol.352
, pp. 99-108
-
-
Zeidan, A.1
Hunter, J.C.2
Javadov, S.3
Karmazyn, M.4
-
79
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
doi:10.1038/372425a0. PMID:7984236
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J.M. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature, 372: 425-432. doi:10.1038/372425a0. PMID:7984236.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
80
-
-
80455155124
-
Leptin's regulation of obesity-induced cardiac extracellular matrix remodeling
-
doi:10.1007/s12012-011-9124-0. PMID:21744298
-
Zibadi, S., Cordova, F., Slack, E.H., Watson, R.R., and Larson, DF. 2011. Leptin's regulation of obesity-induced cardiac extracellular matrix remodeling. Cardiovasc. Toxicol. 11: 325-333. doi:10.1007/s12012-011-9124-0. PMID:21744298.
-
(2011)
Cardiovasc. Toxicol.
, vol.11
, pp. 325-333
-
-
Zibadi, S.1
Cordova, F.2
Slack, E.H.3
Watson, R.R.4
Larson, D.F.5
|