Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes

Cardiovascular Research

Volumn 69, Issue 3, 2006, Pages 716-725

  Madani, Siham ^a   De Girolamo, Sabrina ^a   Muñoz, Diana Marcela ^a   Li, Ren Ke ^b   Sweeney, Gary ^a  

^a YORK UNIVERSITY   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Extracellular matrix; Heart failure; Hypertrophy; Leptin; Obesity

Indexed keywords

ALPHA ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; ENZYME INHIBITOR; GELATIN; GELATINASE A; JANUS KINASE; LEPTIN; LEUCINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYOSIN; PROLINE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; EXTRACELLULAR MATRIX; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; WESTERN BLOTTING; ZYMOGRAPHY;

CELL SIZE; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; FLAVONOIDS; HEART VENTRICLES; HUMANS; IMIDAZOLES; INFANT; JANUS KINASE 1; LEPTIN; MICROSCOPY, PHASE-CONTRAST; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PYRIDINES; TYRPHOSTINS;

EID: 31344444358     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2005.11.022     Document Type: Article

References (53)

1. S.M. Grundy Obesity, metabolic syndrome, and cardiovascular disease J Clin Endocrinol Metab 89 2004 2595 2600
2. J.R. Sowers Obesity as a cardiovascular risk factor Am J Med 115 Suppl 8A 2003 37S 41S
3. V. Sharma, and J.H. McNeill The emerging roles of leptin and ghrelin in cardiovascular physiology and pathophysiology Curr Vasc Pharmacol 3 2005 169 180
4. A.L. Mark, M.L. Correia, K. Rahmouni, and W.G. Haynes Loss of leptin actions in obesity: two concepts with cardiovascular implications Clin Exp Hypertens 26 2004 629 636
5. M.L. Correia, and W.G. Haynes Leptin, obesity and cardiovascular disease Curr Opin Nephrol Hypertens 13 2004 215 223
6. K. Rahmouni, and W.G. Haynes Leptin and the cardiovascular system Recent Prog Horm Res 59 2004 225 244
7. G. Sweeney Leptin signalling Cell Signal 14 2002 655 663
8. R.S. Ahima, and J.S. Flier Leptin Annu Rev Physiol 62 2000 413 437
9. M.L. Correia, and W.G. Haynes Obesity-related hypertension: is there a role for selective leptin resistance? Curr Hypertens Rep 6 2004 230 235
10. P.W. Fedak, S. Verma, R.D. Weisel, and R.K. Li Cardiac remodeling and failure from molecules to man (Part II) Cardiovasc Pathol 14 2005 49 60
11. J.N. Cohn Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition Circulation 91 1995 2504 2507
12. V.G. Florea, V.Y. Mareyev, A.N. Samko, I.A. Orlova, A.J. Coats, and Y.N. Belenkov Left ventricular remodelling: common process in patients with different primary myocardial disorders Int J Cardiol 68 1999 281 287
13. M.L. Lindsey MMP induction and inhibition in myocardial infarction Heart Fail Rev 9 2004 7 19
14. M. Pauschinger, K. Chandrasekharan, and H.P. Schultheiss Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system Heart Fail Rev 9 2004 21 31
15. J.S. Janicki, G.L. Brower, J.D. Gardner, A.L. Chancey, and J.A. Stewart Jr. The dynamic interaction between matrix metalloproteinase activity and adverse myocardial remodeling Heart Fail Rev 9 2004 33 42
16. P. Whittaker Unravelling the mysteries of collagen and cicatrix after myocardial infarction Cardiovasc Res 29 1995 758 762
17. D. Chapman, K.T. Weber, and M. Eghbali Regulation of fibrillar collagen types I and III and basement membrane type IV collagen gene expression in pressure overloaded rat myocardium Circ Res 67 1990 787 794
18. K.T. Weber, J.S. Janicki, S.G. Shroff, R. Pick, R.M. Chen, and R.I. Bashey Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium Circ Res 62 1988 757 765
19. J.E. Bishop, R. Greenbaum, D.G. Gibson, M. Yacoub, and G.J. Laurent Enhanced deposition of predominantly type I collagen in myocardial disease J Mol Cell Cardiol 22 1990 1157 1165
20. D. Mukherjee, and S. Sen Alteration of collagen phenotypes in ischemic cardiomyopathy J Clin Invest 88 1991 1141 1146
21. E. Herpel, S. Singer, C. Flechtenmacher, M. Pritsch, F.U. Sack, and S. Hagl Extracellular matrix proteins and matrix metalloproteinases differ between various right and left ventricular sites in end-stage cardiomyopathies Virchows Arch 446 2005 369 378
22. F. Merante, D.A. Mickle, R.D. Weisel, R.K. Li, L.C. Tumiati, and V. Rao Myocardial aerobic metabolism is impaired in a cell culture model of cyanotic heart disease Am J Physiol 275 1998 H1673 H1681
23. N. Shiono, V. Rao, R.D. Weisel, M. Kawasaki, R.K. Li, and D.A. Mickle l-arginine protects human heart cells from low-volume anoxia and reoxygenation Am J Physiol Heart Circ Physiol 282 2002 H805 H815
24. P. Tajmir, R.B. Ceddia, R.K. Li, I.R. Coe, and G. Sweeney Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase-and phosphatidylinositol 3-kinase-dependent signaling pathways Endocrinology 145 2004 1550 1555
25. V. Rajapurohitam, X.T. Gan, L.A. Kirshenbaum, and M. Karmazyn The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes Circ Res 93 2003 277 279
26. P. Tajmir, J.J. Kwan, M. Kessas, S. Mozammel, and G. Sweeney Acute and chronic leptin treatment mediate contrasting effects on signaling, glucose uptake, and GLUT4 translocation in L6-GLUT4myc myotubes J Cell Physiol 197 2003 122 130
27. J. D'Armiento Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction Trends Cardiovasc Med 12 2002 97 101
28. S. Sader, M. Nian, and P. Liu Leptin: a novel link between obesity, diabetes, cardiovascular risk, and ventricular hypertrophy Circulation 108 2003 644 646
29. Z. Gunja-Smith, A.R. Morales, R. Romanelli, and J.F. Woessner Jr. Remodeling of human myocardial collagen in idiopathic dilated cardiomyopathy. Role of metalloproteinases and pyridinoline cross-links Am J Pathol 148 1996 1639 1648
30. F.G. Spinale Matrix metalloproteinases: regulation and dysregulation in the failing heart Circ Res 90 2002 520 530
31. F.G. Spinale, J.D. Walker, R. Mukherjee, J.P. Iannini, A.T. Keever, and K.P. Gallagher Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits. Beneficial effects on left ventricular and myocyte function Circulation 95 1997 1918 1929
32. M.L. Coker, C.V. Thomas, M.J. Clair, J.W. Hendrick, R.S. Krombach, and Z.S. Galis Myocardial matrix metalloproteinase activity and abundance with congestive heart failure Am J Physiol 274 1998 H1516 H1523
33. A.M. Feldmanm, Y.Y. Li, and C.F. McTiernan Matrix metalloproteinases in pathophysiology and treatment of heart failure Lancet 357 2001 654 655
34. R.T. Lee, and P. Libby Matrix metalloproteinases: not-so-innocent bystanders in heart failure J Clin Invest 106 2000 827 828
35. A.M. Romanic, C.L. Burns-Kurtis, B. Gout, I. Berrebi-Bertrand, and E.H. Ohlstein Matrix metalloproteinase expression in cardiac myocytes following myocardial infarction in the rabbit Life Sci 68 2001 799 814
36. D.E. Kleiner Jr., A. Tuuttila, K. Tryggvason, and W.G. Stetler-Stevenson Stability analysis of latent and active 72-kDa type IV collagenase: the role of tissue inhibitor of metalloproteinases-2 (TIMP-2) Biochemistry 32 1993 1583 1592
37. Y.Y. Li, C.F. McTiernan, and A.M. Feldman Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling Cardiovasc Res 46 2000 214 224
38. P. Zahradka, G. Harding, B. Litchie, S. Thomas, J.P. Werner, and D.P. Wilson Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP Am J Physiol Heart Circ Physiol 287 2004 H2861 H2870
39. H.E. Kim, S.S. Dalal, E. Young, M.J. Legato, M.L. Weisfeldt, and J. D'Armiento Disruption of the myocardial extracellular matrix leads to cardiac dysfunction J Clin Invest 106 2000 857 866
40. S. Matsumura, S. Iwanaga, S. Mochizuki, H. Okamoto, S. Ogawa, and Y. Okada Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice J Clin Invest 115 2005 599 609
41. A. Ducharme, S. Frantz, M. Aikawa, E. Rabkin, M. Lindsey, and L.E. Rohde Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction J Clin Invest 106 2000 55 62
42. A.M. Romanic, S.M. Harrison, W. Bao, C.L. Burns-Kurtis, S. Pickering, and J. Gu Myocardial protection from ischemia/reperfusion injury by targeted deletion of matrix metalloproteinase-9 Cardiovasc Res 54 2002 549 558
43. L.E. Rohde, A. Ducharme, L.H. Arroyo, M. Aikawa, G.H. Sukhova, and A. Lopez-Anaya Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice Circulation 99 1999 3063 3070
44. K. Kume, K. Satomura, S. Nishisho, E. Kitaoka, K. Yamanouchi, and S. Tobiume Potential role of leptin in endochondral ossification J Histochem Cytochem 50 2002 159 169
45. M. Castellucci, R. De Matteis, A. Meisser, R. Cancello, V. Monsurro, and D. Islami Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion Mol Hum Reprod 6 2000 951 958
46. H.Y. Park, H.M. Kwon, H.J. Lim, B.K. Hong, J.Y. Lee, and B.E. Park Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro Exp Mol Med 33 2001 95 102
47. N.K. Saxena, G. Saliba, J.J. Floyd, and F.A. Anania Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells J Cell Biochem 89 2003 311 320
48. M. Tang, J.J. Potter, and E. Mezey Leptin enhances the effect of transforming growth factor beta in increasing type I collagen formation Biochem Biophys Res Commun 297 2002 906 911
49. D.C. Han, M. Isono, S. Chen, A. Casaretto, S.W. Hong, and G. Wolf Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-beta type II receptor expression Kidney Int 59 2001 1315 1323
50. G. Wolf, A. Hamann, D.C. Han, U. Helmchen, F. Thaiss, and F.N. Ziyadeh Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments] Kidney Int 56 1999 860 872
51. F.P. Xu, M.S. Chen, Y.Z. Wang, Q. Yi, S.B. Lin, and A.F. Chen Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes Circulation 110 2004 1269 1275
52. L.A. Barouch, D.E. Berkowitz, R.W. Harrison, C.P. O'Donnell, and J.M. Hare Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice Circulation 108 2003 754 759
53. A.L. Mark, M.L. Correia, K. Rahmouni, and W.G. Haynes Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications J Hypertens 20 2002 1245 1250