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Volumn 77, Issue 1, 2008, Pages 64-72

Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCK-dependent p38 MAPK translocation to nuclei

Author keywords

Cardiomyocytes; Caveolae; Hypertrophy; Leptin; RhoA

Indexed keywords

F ACTIN; G ACTIN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 38849188633     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvm020     Document Type: Article
Times cited : (83)

References (38)
  • 2
    • 27744518880 scopus 로고    scopus 로고
    • Leptin induces vascular smooth muscle cell hypertrophy through angiotensin II- and endothelin-1-dependent mechanisms and mediates stretch-induced hypertrophy
    • Zeidan A, Purdham DM, Rajapurohitam V, Javadov S, Chakrabarti S, Karmazyn M. Leptin induces vascular smooth muscle cell hypertrophy through angiotensin II- and endothelin-1-dependent mechanisms and mediates stretch-induced hypertrophy. J Pharmacol Exp Ther 2005;315:1075-1084.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1075-1084
    • Zeidan, A.1    Purdham, D.M.2    Rajapurohitam, V.3    Javadov, S.4    Chakrabarti, S.5    Karmazyn, M.6
  • 4
    • 0033198793 scopus 로고    scopus 로고
    • Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis
    • Sano S, Itami S, Takeda K, Tarutani M, Yamaguchi Y, Miura H et al. Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis. EMBO J 1999;18:4657-4668.
    • (1999) EMBO J , vol.18 , pp. 4657-4668
    • Sano, S.1    Itami, S.2    Takeda, K.3    Tarutani, M.4    Yamaguchi, Y.5    Miura, H.6
  • 5
    • 0032971218 scopus 로고    scopus 로고
    • Leptin promotes aggregation of human platelets via the long form of its receptor
    • Nakata M, Yada T, Soejima N, Maruyama I. Leptin promotes aggregation of human platelets via the long form of its receptor. Diabetes 1999;48:426-429.
    • (1999) Diabetes , vol.48 , pp. 426-429
    • Nakata, M.1    Yada, T.2    Soejima, N.3    Maruyama, I.4
  • 6
    • 0041857804 scopus 로고    scopus 로고
    • The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes
    • Rajapurohitam V, Gan XT, Kirshenbaum LA, Karmazyn M. The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. Circ Res 2003;93:277-279.
    • (2003) Circ Res , vol.93 , pp. 277-279
    • Rajapurohitam, V.1    Gan, X.T.2    Kirshenbaum, L.A.3    Karmazyn, M.4
  • 7
    • 4444303576 scopus 로고    scopus 로고
    • Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes
    • Xu FP, Chen MS, Wang YZ, Yi Q, Lin SB, Chen AF et al. Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes. Circulation 2004;110:1269-1275.
    • (2004) Circulation , vol.110 , pp. 1269-1275
    • Xu, F.P.1    Chen, M.S.2    Wang, Y.Z.3    Yi, Q.4    Lin, S.B.5    Chen, A.F.6
  • 8
    • 1642464978 scopus 로고    scopus 로고
    • Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways
    • Tajmir P, Ceddia RB, Li RK, Coe IR, Sweeney G. Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways. Endocrinology 2004;14:1550-1555.
    • (2004) Endocrinology , vol.14 , pp. 1550-1555
    • Tajmir, P.1    Ceddia, R.B.2    Li, R.K.3    Coe, I.R.4    Sweeney, G.5
  • 9
    • 0042018759 scopus 로고    scopus 로고
    • Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice
    • Barouch LA, Berkowitz DE, Harrison RW, O'Donnell CP, Hare JM. Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. Circulation 2003;108:754-759.
    • (2003) Circulation , vol.108 , pp. 754-759
    • Barouch, L.A.1    Berkowitz, D.E.2    Harrison, R.W.3    O'Donnell, C.P.4    Hare, J.M.5
  • 10
    • 33748130863 scopus 로고    scopus 로고
    • Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes
    • Zeidan A, Javadov S, Karmazyn M. Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes. Cardiovasc Res 2006;72:101-111.
    • (2006) Cardiovasc Res , vol.72 , pp. 101-111
    • Zeidan, A.1    Javadov, S.2    Karmazyn, M.3
  • 11
    • 0027443234 scopus 로고
    • Caveolae: Where incoming outgoing messengers meet
    • Anderson RG. Caveolae: where incoming outgoing messengers meet. Proc Natl Acad Sci USA 1993;90:10909-10913.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10909-10913
    • Anderson, R.G.1
  • 12
    • 0042733080 scopus 로고    scopus 로고
    • Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: Cytoskeletal regulation of ERK translocation
    • Kawamura S, Miyamoto S, Brown JH. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J Biol Chem 2003;278:31111-31117.
    • (2003) J Biol Chem , vol.278 , pp. 31111-31117
    • Kawamura, S.1    Miyamoto, S.2    Brown, J.H.3
  • 13
    • 0036733284 scopus 로고    scopus 로고
    • Caveolae: From cell biology to animal physiology
    • Razani B, Woodman SE, Lisanti MP. Caveolae: from cell biology to animal physiology. Pharmacol Rev 2002;54:431-467.
    • (2002) Pharmacol Rev , vol.54 , pp. 431-467
    • Razani, B.1    Woodman, S.E.2    Lisanti, M.P.3
  • 14
    • 15844401780 scopus 로고    scopus 로고
    • Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins
    • Song KS, Scherer PE, Tang Z, Okamoto T, Li S, Chafel M et al. Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins. J Biol Chem 1996;271: 15160-15165.
    • (1996) J Biol Chem , vol.271 , pp. 15160-15165
    • Song, K.S.1    Scherer, P.E.2    Tang, Z.3    Okamoto, T.4    Li, S.5    Chafel, M.6
  • 15
  • 16
    • 0029075372 scopus 로고
    • Evidence for a regulated interaction between heterotrimeric G proteins and caveolin
    • Li S, Okamoto T, Chun M, Sargiacomo M, Casanova JE, Hansen SH et al. Evidence for a regulated interaction between heterotrimeric G proteins and caveolin. J Biol Chem 1995;270:15693-15701.
    • (1995) J Biol Chem , vol.270 , pp. 15693-15701
    • Li, S.1    Okamoto, T.2    Chun, M.3    Sargiacomo, M.4    Casanova, J.E.5    Hansen, S.H.6
  • 17
    • 0032577647 scopus 로고    scopus 로고
    • Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain
    • Engelman JA, Chu C, Lin A, Jo H, Ikezu T, Okamoto T et al. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett 1998;428:205-211.
    • (1998) FEBS Lett , vol.428 , pp. 205-211
    • Engelman, J.A.1    Chu, C.2    Lin, A.3    Jo, H.4    Ikezu, T.5    Okamoto, T.6
  • 18
    • 0035971086 scopus 로고    scopus 로고
    • Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control
    • Parpal S, Karlsson M, Thorn H, Stralfors P. Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control. J Biol Chem 2001;276:9670-9678.
    • (2001) J Biol Chem , vol.276 , pp. 9670-9678
    • Parpal, S.1    Karlsson, M.2    Thorn, H.3    Stralfors, P.4
  • 19
    • 0028812541 scopus 로고
    • Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor
    • Klein U, Gimpl G, Fahrenholz F. Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor. Biochemistry 1995;34:13784- 13793.
    • (1995) Biochemistry , vol.34 , pp. 13784-13793
    • Klein, U.1    Gimpl, G.2    Fahrenholz, F.3
  • 20
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • Treisman R. Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol 1996;8:205-215.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 205-215
    • Treisman, R.1
  • 21
    • 0029003932 scopus 로고
    • Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe
    • Scherer PE, Tang Z, Chun M, Sargiacomo M, Lodish HF, Lisanti MP. Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe. J Biol Chem 1995;270:16395-16401.
    • (1995) J Biol Chem , vol.270 , pp. 16395-16401
    • Scherer, P.E.1    Tang, Z.2    Chun, M.3    Sargiacomo, M.4    Lodish, H.F.5    Lisanti, M.P.6
  • 22
    • 0029086362 scopus 로고
    • De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin
    • Fra AM, Williamson E, Simons K, Parton RG. De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc Natl Acad Sci USA 1995;92:8655-8659.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8655-8659
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 23
  • 24
    • 0025095763 scopus 로고
    • Three-dimensional observation on sarcoplasmic reticulum and caveolae in myocardium of spontaneously hypertensive rats
    • Goto Y, Yoshikane H, Honda M, Morioka S, Yamori Y, Moriyama K. Three-dimensional observation on sarcoplasmic reticulum and caveolae in myocardium of spontaneously hypertensive rats. J Submicrosc Cytol Pathol 1990;22:535-542.
    • (1990) J Submicrosc Cytol Pathol , vol.22 , pp. 535-542
    • Goto, Y.1    Yoshikane, H.2    Honda, M.3    Morioka, S.4    Yamori, Y.5    Moriyama, K.6
  • 26
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane
    • Okamoto T, Schlegel A, Scherer PE, Lisanti MP. Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane. J Biol Chem 1998;273:5419-5422.
    • (1998) J Biol Chem , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 27
    • 0031765341 scopus 로고    scopus 로고
    • Role of plasmalemmal caveolae in signal transduction
    • Shaul PW, Anderson RG. Role of plasmalemmal caveolae in signal transduction. Am J Physiol 1998;275:L843-L851.
    • (1998) Am J Physiol , vol.275
    • Shaul, P.W.1    Anderson, R.G.2
  • 28
    • 0037064033 scopus 로고    scopus 로고
    • Caveolin-3 knock-out mice develop a progressive cardiomyopathy show hyperactivation of the p42/44 MAPK cascade
    • Woodman SE, Park DS, Cohen AW, Cheung MW, Chandra M, Shirani J et al. Caveolin-3 knock-out mice develop a progressive cardiomyopathy show hyperactivation of the p42/44 MAPK cascade. J Biol Chem 2002;277:38988-38997.
    • (2002) J Biol Chem , vol.277 , pp. 38988-38997
    • Woodman, S.E.1    Park, D.S.2    Cohen, A.W.3    Cheung, M.W.4    Chandra, M.5    Shirani, J.6
  • 29
    • 0036080902 scopus 로고    scopus 로고
    • Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype
    • Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M et al. Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype. Am J Pathol 2002;160:2207-2217.
    • (2002) Am J Pathol , vol.160 , pp. 2207-2217
    • Park, D.S.1    Woodman, S.E.2    Schubert, W.3    Cohen, A.W.4    Frank, P.G.5    Chandra, M.6
  • 30
    • 4043050179 scopus 로고    scopus 로고
    • Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238
    • Ferrandi M, Molinari I, Barassi P, Minotti E, Bianchi G, Ferrari P. Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238. J Biol Chem 2004;279:33306-33314.
    • (2004) J Biol Chem , vol.279 , pp. 33306-33314
    • Ferrandi, M.1    Molinari, I.2    Barassi, P.3    Minotti, E.4    Bianchi, G.5    Ferrari, P.6
  • 31
    • 0033597894 scopus 로고    scopus 로고
    • Polarized distribution of endogenous Rac1 and RhoA at the cell surface
    • Michaely PA, Mineo C, Ying YS, Anderson RG. Polarized distribution of endogenous Rac1 and RhoA at the cell surface. J Biol Chem 1999;274:21430-21436.
    • (1999) J Biol Chem , vol.274 , pp. 21430-21436
    • Michaely, P.A.1    Mineo, C.2    Ying, Y.S.3    Anderson, R.G.4
  • 32
    • 0034631516 scopus 로고    scopus 로고
    • Inhibition of PKC alpha and rhoA translocation in differentiated smooth muscle by a caveolin scaffolding domain peptide
    • Taggart MJ, Leavis P, Feron O, Morgan KG. Inhibition of PKC alpha and rhoA translocation in differentiated smooth muscle by a caveolin scaffolding domain peptide. Exp Cell Res 2000;258:72-81.
    • (2000) Exp Cell Res , vol.258 , pp. 72-81
    • Taggart, M.J.1    Leavis, P.2    Feron, O.3    Morgan, K.G.4
  • 33
    • 0032572534 scopus 로고    scopus 로고
    • Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy?
    • Clerk A, Michael A, Sugden PH. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy? J Cell Biol 1998;142:523-535.
    • (1998) J Cell Biol , vol.142 , pp. 523-535
    • Clerk, A.1    Michael, A.2    Sugden, P.H.3
  • 34
    • 13844280463 scopus 로고    scopus 로고
    • Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells
    • Shin HJ, Oh J, Kang SM, Lee JH, Shin MJ, Hwang KC et al. Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells. Biochem Biophys Res Commun 2005;329:18-24.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 18-24
    • Shin, H.J.1    Oh, J.2    Kang, S.M.3    Lee, J.H.4    Shin, M.J.5    Hwang, K.C.6
  • 35
    • 0031844392 scopus 로고    scopus 로고
    • Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy
    • Nemoto S, Sheng Z, Lin A. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Mol Cell Biol 1998;18:3518-3526.
    • (1998) Mol Cell Biol , vol.18 , pp. 3518-3526
    • Nemoto, S.1    Sheng, Z.2    Lin, A.3
  • 36
    • 0033081066 scopus 로고    scopus 로고
    • Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
    • Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J 1999;18:664-674.
    • (1999) EMBO J , vol.18 , pp. 664-674
    • Brunet, A.1    Roux, D.2    Lenormand, P.3    Dowd, S.4    Keyse, S.5    Pouyssegur, J.6
  • 37
    • 0029827366 scopus 로고    scopus 로고
    • The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light
    • Price MA, Cruzalegui FH, Treisman R. The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J 1996;15:6552-6563.
    • (1996) EMBO J , vol.15 , pp. 6552-6563
    • Price, M.A.1    Cruzalegui, F.H.2    Treisman, R.3
  • 38
    • 0035889083 scopus 로고    scopus 로고
    • Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton
    • Aplin AE, Juliano RL. Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton. J Cell Biol 2001;155:187-191.
    • (2001) J Cell Biol , vol.155 , pp. 187-191
    • Aplin, A.E.1    Juliano, R.L.2


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