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Volumn 28, Issue 4, 2013, Pages 314-328

Vitamin C in disease prevention and cure: An overview

Author keywords

Atherosclerosis; Cancer; Diabetes; Heavy metal toxicity; Immunity; Infertility; Vitamin C

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BILE ACID; CHOLESTEROL; FOLIC ACID; IRON; SEROTONIN; TRYPTOPHAN; VITAMIN B GROUP;

EID: 84885074494     PISSN: 09701915     EISSN: 09740422     Source Type: Journal    
DOI: 10.1007/s12291-013-0375-3     Document Type: Review
Times cited : (369)

References (227)
  • 2
    • 0028228342 scopus 로고
    • Cloning and chromosomal mapping of the human nonfunctional gene for l-gulono-gamma-lactone oxidase, the enzyme for l-ascorbic acid biosynthesis missing in man
    • 8175804 1:CAS:528:DyaK2cXktVagsb0%3D
    • Nishikimi M, Fukuyama R, Minoshima S, Shimizu N, Yagi K. Cloning and chromosomal mapping of the human nonfunctional gene for l-gulono-gamma-lactone oxidase, the enzyme for l-ascorbic acid biosynthesis missing in man. J Biol Chem. 1994;269:13685-8.
    • (1994) J Biol Chem , vol.269 , pp. 13685-13688
    • Nishikimi, M.1    Fukuyama, R.2    Minoshima, S.3    Shimizu, N.4    Yagi, K.5
  • 4
    • 0014483799 scopus 로고
    • + dependent active transport of ascorbic acid in guinea pigs
    • 5774241 1:CAS:528:DyaF1MXnsFGgtA%3D%3D
    • + dependent active transport of ascorbic acid in guinea pigs. Am J Clin Nutr. 1969;22:318.
    • (1969) Am J Clin Nutr , vol.22 , pp. 318
    • Stevenson, N.R.1    Brush, M.K.2
  • 5
    • 0033987864 scopus 로고    scopus 로고
    • Glucose modulates vitamin C transport in adult human small intestinal brush border membrane vesicles
    • 10613768 1:CAS:528:DC%2BD3cXkt12rug%3D%3D
    • Malo C, Wilson JX. Glucose modulates vitamin C transport in adult human small intestinal brush border membrane vesicles. J Nutr. 2000;130:63-9.
    • (2000) J Nutr , vol.130 , pp. 63-69
    • Malo, C.1    Wilson, J.X.2
  • 6
    • 1242317668 scopus 로고    scopus 로고
    • Sodium dependent ascorbic acid transporter family SLC23
    • Takanga H, Mackenzie B, Hediger MA. Sodium dependent ascorbic acid transporter family SLC23. Pflugers Arch. 2004;447:677-82.
    • (2004) Pflugers Arch , vol.447 , pp. 677-682
    • Takanga, H.1    Mackenzie, B.2    Hediger, M.A.3
  • 7
    • 34948850436 scopus 로고
    • Ascorbic acid absorption in malabsorption
    • 14266809 1:STN:280:DyaF2M%2FntFelsQ%3D%3D
    • Stewart JS, Booth CC. Ascorbic acid absorption in malabsorption. Acta Gastroenterol Belg. 1964;27:567-8.
    • (1964) Acta Gastroenterol Belg , vol.27 , pp. 567-568
    • Stewart, J.S.1    Booth, C.C.2
  • 8
    • 0001492689 scopus 로고
    • The mechanism of the excretion of vitamin C by the human kidney
    • 16694625 1:CAS:528:DyaA1MXovFOl
    • Ralli EP, Friedman GJ, Rubin SH. The mechanism of the excretion of vitamin C by the human kidney. J Clin Invest. 1938;17:765-70.
    • (1938) J Clin Invest , vol.17 , pp. 765-770
    • Ralli, E.P.1    Friedman, G.J.2    Rubin, S.H.3
  • 9
    • 0017852330 scopus 로고
    • Demonstration of saturation kinetics in the intestinal absorption of vitamin C in man and the guinea pig
    • 209065
    • Nelson EW, Lane H, Fabri PJ, Scott B. Demonstration of saturation kinetics in the intestinal absorption of vitamin C in man and the guinea pig. J Clin Pharmacol. 1978;18:325-35.
    • (1978) J Clin Pharmacol , vol.18 , pp. 325-335
    • Nelson, E.W.1    Lane, H.2    Fabri, P.J.3    Scott, B.4
  • 10
    • 0036258606 scopus 로고    scopus 로고
    • Decreased expression of the vitamin C transporter SVCT1 by ascorbic acid in a human intestinal epithelial cell line
    • 11895172 1:CAS:528:DC%2BD38Xht1Whsbc%3D
    • MacDonald L, Thumser AE, Sharp P. Decreased expression of the vitamin C transporter SVCT1 by ascorbic acid in a human intestinal epithelial cell line. Br J Nutr. 2002;87(20):97-100.
    • (2002) Br J Nutr , vol.87 , Issue.20 , pp. 97-100
    • Macdonald, L.1    Thumser, A.E.2    Sharp, P.3
  • 11
    • 23944482400 scopus 로고    scopus 로고
    • Regulation of vitamin C transport
    • 1:CAS:528:DC%2BD2MXpvF2msbc%3D
    • Wilson JX. Regulation of vitamin C transport. Ann Rev Nutr. 2005;25:105-25.
    • (2005) Ann Rev Nutr , vol.25 , pp. 105-125
    • Wilson, J.X.1
  • 12
    • 1842435160 scopus 로고    scopus 로고
    • Vitamin C pharmacokinetics: Implications for oral and intravenous use
    • 15068981 1:CAS:528:DC%2BD2cXjsFSqsrw%3D
    • Padayatty SJ, Sun H, Wang YH, Riordan HD, Hewitt SM, Katz A, et al. Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann Intern Med. 2004;140:533-7.
    • (2004) Ann Intern Med , vol.140 , pp. 533-537
    • Padayatty, S.J.1    Sun, H.2    Wang, Y.H.3    Riordan, H.D.4    Hewitt, S.M.5    Katz, A.6
  • 13
    • 9244219627 scopus 로고    scopus 로고
    • Vitamin C pharmacokinetics in healthy volunteers: Evidence for a recommended dietary allowance
    • 8623000 1:CAS:528:DyaK28XisVWiu7Y%3D
    • Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR, et al. Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc Natl Acad Sci USA. 1996;93:3704-9.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3704-3709
    • Levine, M.1    Conry-Cantilena, C.2    Wang, Y.3    Welch, R.W.4    Washko, P.W.5    Dhariwal, K.R.6
  • 14
    • 0026638654 scopus 로고
    • Adaptive regulation of ascorbate transport in osteoblastic cells
    • 1414486 1:CAS:528:DyaK38Xlt1ylsL8%3D
    • Dixon SJ, Wilson JX. Adaptive regulation of ascorbate transport in osteoblastic cells. J Bone Miner Res. 1992;7:675-81.
    • (1992) J Bone Miner Res , vol.7 , pp. 675-681
    • Dixon, S.J.1    Wilson, J.X.2
  • 15
    • 34948910268 scopus 로고    scopus 로고
    • New developments and novel therapeutic perspectives for vitamin C
    • 17884994 1:CAS:528:DC%2BD2sXhtFeksb3E
    • Li Y, Schellhorn Herb E. New developments and novel therapeutic perspectives for vitamin C. J Nutr. 2007;137:2171-84.
    • (2007) J Nutr , vol.137 , pp. 2171-2184
    • Li, Y.1    Schellhorn Herb, E.2
  • 16
    • 0018771190 scopus 로고
    • Steady state turnover and body pool of ascorbic acid in man
    • 420145 1:CAS:528:DyaE1MXktVChs7w%3D
    • Kallner AB, Hartmann D, Horning DH. Steady state turnover and body pool of ascorbic acid in man. Am J Clin Nutr. 1979;32:530-9.
    • (1979) Am J Clin Nutr , vol.32 , pp. 530-539
    • Kallner, A.B.1    Hartmann, D.2    Horning, D.H.3
  • 17
    • 0030859382 scopus 로고    scopus 로고
    • The effect of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with low or high cholesterol levels
    • 9329641 1:CAS:528:DyaK2sXmvFCru7w%3D
    • Anderson D, Phillips BJ, Yu T, Edwards AJ, Ayesh R, Butterworth KR. The effect of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with low or high cholesterol levels. Environ Mol Mutagen. 1997;30:161-74.
    • (1997) Environ Mol Mutagen , vol.30 , pp. 161-174
    • Anderson, D.1    Phillips, B.J.2    Yu, T.3    Edwards, A.J.4    Ayesh, R.5    Butterworth, K.R.6
  • 18
    • 0032890707 scopus 로고    scopus 로고
    • Biomarkers for establishing a tolerable upper intake level for vitamin C
    • Johnson CS. Biomarkers for establishing a tolerable upper intake level for vitamin C. Nutr Rev. 1999;57:71-7.
    • (1999) Nutr Rev , vol.57 , pp. 71-77
    • Johnson, C.S.1
  • 19
    • 3042559581 scopus 로고    scopus 로고
    • Vitamin C. In human health and disease is still a mystery? An overview
    • 14498993
    • Naidu AK, Vitamin C. In human health and disease is still a mystery? An overview. Nutr J. 2003;2:7.
    • (2003) Nutr J , vol.2 , pp. 7
    • Naidu, A.K.1
  • 20
    • 0022635104 scopus 로고
    • New concepts in the biology and biochemistry of ascorbic acid
    • Levin M. New concepts in the biology and biochemistry of ascorbic acid. New Engl J Med. 1986;31:892-902.
    • (1986) New Engl J Med , vol.31 , pp. 892-902
    • Levin, M.1
  • 21
    • 11144265659 scopus 로고    scopus 로고
    • Transport and intracellular accumulation of vitamin C in endothelial cells: Relevance to collagen synthesis
    • 15629121 1:CAS:528:DC%2BD2MXksFWn
    • May JM, Zhi-chao Q. Transport and intracellular accumulation of vitamin C in endothelial cells: relevance to collagen synthesis. Arch Biochem Biophys. 2005;434:178-86.
    • (2005) Arch Biochem Biophys , vol.434 , pp. 178-186
    • May, J.M.1    Zhi-Chao, Q.2
  • 22
    • 34249331306 scopus 로고    scopus 로고
    • Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative
    • 17306970 1:CAS:528:DC%2BD2sXlvVOks7Y%3D
    • Maehata Y, Takamizawa S, Ozawa S, Izukuri K, Kato Y, Sato S, et al. Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative. Matrix Biol. 2007;26(5):371-81.
    • (2007) Matrix Biol , vol.26 , Issue.5 , pp. 371-381
    • Maehata, Y.1    Takamizawa, S.2    Ozawa, S.3    Izukuri, K.4    Kato, Y.5    Sato, S.6
  • 23
    • 84872354647 scopus 로고    scopus 로고
    • Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts
    • Kishimoto Y, Saito N, Kurita K, Shimokado K, Maruyama N, Ishigami A. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Biochem Biophys Res Commun. 2013;30(2):579-84.
    • (2013) Biochem Biophys Res Commun , vol.30 , Issue.2 , pp. 579-584
    • Kishimoto, Y.1    Saito, N.2    Kurita, K.3    Shimokado, K.4    Maruyama, N.5    Ishigami, A.6
  • 24
    • 0017891065 scopus 로고
    • Carnitine biosynthesis-beta hydroxylation of trimethyllysine by an α-ketoglutarate dependent mitochondrial dioxygenase
    • 627563 1:CAS:528:DyaE1cXhsVOlsrw%3D
    • Hulse JD, Ellis SR, Henderson LM. Carnitine biosynthesis-beta hydroxylation of trimethyllysine by an α-ketoglutarate dependent mitochondrial dioxygenase. J Biol Chem. 1978;253:1654-9.
    • (1978) J Biol Chem , vol.253 , pp. 1654-1659
    • Hulse, J.D.1    Ellis, S.R.2    Henderson, L.M.3
  • 25
    • 0025718708 scopus 로고
    • Ascorbic acid and carnitine biosynthesis
    • 1962562 1:CAS:528:DyaK38XktVWmtQ%3D%3D
    • Rebouche CJ. Ascorbic acid and carnitine biosynthesis. Am J Clin Nutr. 1991;54(6):1147S-52S.
    • (1991) Am J Clin Nutr , vol.54 , Issue.6
    • Rebouche, C.J.1
  • 26
    • 0015544986 scopus 로고
    • Ascorbic acid and the glycosaminoglycans
    • 4267127 1:CAS:528:DyaE3sXkt1Omt7k%3D
    • Cameron E, Pauling L. Ascorbic acid and the glycosaminoglycans. Oncology. 1973;27:181-92.
    • (1973) Oncology , vol.27 , pp. 181-192
    • Cameron, E.1    Pauling, L.2
  • 27
    • 0015786313 scopus 로고
    • Ascorbic acid and catabolism of cholesterol
    • Anon
    • Anon. Ascorbic acid and catabolism of cholesterol. Nutr Rev 1973;31:154.
    • (1973) Nutr Rev , vol.31 , pp. 154
  • 28
    • 0024502829 scopus 로고
    • Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency
    • 1:CAS:528:DyaL1MXktVKgs74%3D
    • Sharma P, Pramod J, Kothari LK, Ranka R, Sharma S. Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency. IJCB. 1989;4:62-4.
    • (1989) IJCB , vol.4 , pp. 62-64
    • Sharma, P.1    Pramod, J.2    Kothari, L.K.3    Ranka, R.4    Sharma, S.5
  • 29
    • 0025534714 scopus 로고
    • Effect of vitamin C deficiency and excess on the liver: A histopathological and biochemical study in guinea pigs fed normal or high cholesterol diet
    • 1:STN:280:DyaK38%2FosVCiuw%3D%3D
    • Sharma P, Pramod J, Sharma PK, Sapra M, Kothari LK. Effect of vitamin C deficiency and excess on the liver: a histopathological and biochemical study in guinea pigs fed normal or high cholesterol diet. Ind J Pathol Microbiol. 1990;33(4):307-13.
    • (1990) Ind J Pathol Microbiol , vol.33 , Issue.4 , pp. 307-313
    • Sharma, P.1    Pramod, J.2    Sharma, P.K.3    Sapra, M.4    Kothari, L.K.5
  • 30
    • 0343476331 scopus 로고
    • Role of ascorbic acid in lipid metabolism
    • A. Seith B.M. Toblert (eds) American Chemical Society Washington DC
    • Ginter E, Bobek P, Jurcovicova M. Role of ascorbic acid in lipid metabolism. In: Seith PA, Toblert BM, editors. Ascorbic acid, chemistry, metabolism and uses. Washington DC: American Chemical Society; 1982. p. 381-93.
    • (1982) Ascorbic Acid, Chemistry, Metabolism and Uses , pp. 381-393
    • Ginter, E.1    Bobek, P.2    Jurcovicova, M.3
  • 31
    • 0030964209 scopus 로고    scopus 로고
    • The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: Prolongation of the nucleation time
    • 9179545 1:CAS:528:DyaK2sXjvVOktLs%3D
    • Gustafsson U, Wang FH, Axelson M, Kallner A, Sahlin S, Einarsson K. The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: prolongation of the nucleation time. Eur J Clin Invest. 1997;27(5):387-91.
    • (1997) Eur J Clin Invest , vol.27 , Issue.5 , pp. 387-391
    • Gustafsson, U.1    Wang, F.H.2    Axelson, M.3    Kallner, A.4    Sahlin, S.5    Einarsson, K.6
  • 33
    • 0017088921 scopus 로고
    • A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold
    • 788820 1:STN:280:DyaE2s%2Fit1OltQ%3D%3D
    • Elwood PC, Lee HP, St Leger AS, Baird M, Howard AN. A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold. Br J Prev Soc Med. 1976;30(3):193-6.
    • (1976) Br J Prev Soc Med , vol.30 , Issue.3 , pp. 193-196
    • Elwood, P.C.1    Lee, H.P.2    St Leger, A.S.3    Baird, M.4    Howard, A.N.5
  • 34
    • 35248820149 scopus 로고    scopus 로고
    • Vitamin C for preventing and treating the common cold
    • doi: 10.1002/14651858.CD000980
    • Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013;1:CD000980. doi: 10.1002/14651858.CD000980.
    • (2013) Cochrane Database Syst Rev. , vol.1
    • Hemilä, H.1    Chalker, E.2
  • 36
    • 0033603026 scopus 로고    scopus 로고
    • Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis
    • 10357874 1:CAS:528:DyaK1MXjsFWnsr4%3D
    • Campbell JD, Cole M, Bunditrutavorn B, Vell AT. Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis. Cell Immunol. 1999;194:1-5.
    • (1999) Cell Immunol , vol.194 , pp. 1-5
    • Campbell, J.D.1    Cole, M.2    Bunditrutavorn, B.3    Vell, A.T.4
  • 37
    • 33644697589 scopus 로고    scopus 로고
    • Immune-enhancing role of vitamin C and zinc and effect on clinical conditions
    • 16373990 1:CAS:528:DC%2BD28XhvVyquro%3D
    • Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94.
    • (2006) Ann Nutr Metab , vol.50 , Issue.2 , pp. 85-94
    • Wintergerst, E.S.1    Maggini, S.2    Hornig, D.H.3
  • 38
    • 0008768466 scopus 로고
    • The effect of vitamin C on healing wounds
    • 21002288 1:CAS:528:DyaH2sXot1Cn
    • Bourne GH. The effect of vitamin C on healing wounds. Proc Nutr Soc. 1946;4:204.
    • (1946) Proc Nutr Soc , vol.4 , pp. 204
    • Bourne, G.H.1
  • 39
    • 0000222181 scopus 로고
    • Metabolism of l-ascorbic acid-1-C14 in man
    • 13525409 1:CAS:528:DyaG1cXmt1Sruw%3D%3D
    • Hellman L, Burns JJ. Metabolism of l-ascorbic acid-1-C14 in man. J Biol Chem. 1958;230:923-30.
    • (1958) J Biol Chem , vol.230 , pp. 923-930
    • Hellman, L.1    Burns, J.J.2
  • 40
    • 34247862017 scopus 로고    scopus 로고
    • Ascorbic acid increases healing of excision wounds of mice whole body exposed to different doses of γ-radiation
    • 17223272
    • Jagetia GC, Rajanikant GK, Mallikarjun Rao KVN. Ascorbic acid increases healing of excision wounds of mice whole body exposed to different doses of γ-radiation. Burns. 2007;33(4):484-94.
    • (2007) Burns , vol.33 , Issue.4 , pp. 484-494
    • Jagetia, G.C.1    Rajanikant, G.K.2    Mallikarjun Rao, K.V.N.3
  • 41
    • 0019746191 scopus 로고
    • Bioavailability of dietary iron in man
    • 6764713 1:CAS:528:DyaL3MXkvFGrsb0%3D
    • Hallberg L. Bioavailability of dietary iron in man. Annu Rev Nutr. 1981;1:123-7.
    • (1981) Annu Rev Nutr , vol.1 , pp. 123-127
    • Hallberg, L.1
  • 42
    • 0025238701 scopus 로고
    • Ascorbic acid safety: Analysis factors affecting iron absorption
    • 2184546 1:CAS:528:DyaK3cXitFGmsLY%3D
    • Bendich A, Cohen M. Ascorbic acid safety: analysis factors affecting iron absorption. Toxicol Lett. 1990;51:189-90.
    • (1990) Toxicol Lett , vol.51 , pp. 189-190
    • Bendich, A.1    Cohen, M.2
  • 43
    • 84878385582 scopus 로고    scopus 로고
    • Effects of dietary factors on the pharmacokinetics of (58)Fe-labeled hemin after oral administration in normal rats and the iron-deficient rats
    • 23584844 1:CAS:528:DC%2BC3sXosVCrtrg%3D
    • Zhang Y, Zhao D, Xu J, Xu C, Dong C, Liu Q, et al. Effects of dietary factors on the pharmacokinetics of (58)Fe-labeled hemin after oral administration in normal rats and the iron-deficient rats. Biol Trace Elem Res. 2013;153(1-3):243-50.
    • (2013) Biol Trace Elem Res , vol.153 , Issue.1-3 , pp. 243-250
    • Zhang, Y.1    Zhao, D.2    Xu, J.3    Xu, C.4    Dong, C.5    Liu, Q.6
  • 44
    • 0035701666 scopus 로고    scopus 로고
    • Influence of amla fruits (Emblica officinalis) on the bio-availability of iron from staple cereals and pulses
    • 1:CAS:528:DC%2BD38XhtFGjs7o%3D
    • Gowri S, Patel K, Prakash J, Srinivasan K. Influence of amla fruits (Emblica officinalis) on the bio-availability of iron from staple cereals and pulses. Nutr Res. 2001;21(12):1483-92.
    • (2001) Nutr Res , vol.21 , Issue.12 , pp. 1483-1492
    • Gowri, S.1    Patel, K.2    Prakash, J.3    Srinivasan, K.4
  • 45
    • 84860121634 scopus 로고    scopus 로고
    • Vitamin C affects the expression of hepcidin and erythropoietin receptor in HepG2 cells
    • 22227182 1:CAS:528:DC%2BC38XlvFeitro%3D
    • Chiu PF, Ko SY, Chang CC. Vitamin C affects the expression of hepcidin and erythropoietin receptor in HepG2 cells. J Ren Nutr. 2012;22(3):373-6.
    • (2012) J Ren Nutr , vol.22 , Issue.3 , pp. 373-376
    • Chiu, P.F.1    Ko, S.Y.2    Chang, C.C.3
  • 46
    • 84880031116 scopus 로고    scopus 로고
    • Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism
    • 23481043
    • Darius Lane JR, Chikhani S, Richardson V, Richardson Des R. Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism. Biochim Biophys Acta. 2013;1833(6):1527-41.
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.6 , pp. 1527-1541
    • Darius Lane, J.R.1    Chikhani, S.2    Richardson, V.3    Richardson Des, R.4
  • 47
    • 0021045327 scopus 로고
    • On the cytotoxicity of vitamin C and metal ions: A site specific Fenton mechanism
    • 6317379 1:CAS:528:DyaL2cXjtlGnsw%3D%3D
    • Samuni A, Aronovitch J, Godinger D, Chevion M, Czapski G. On the cytotoxicity of vitamin C and metal ions: a site specific Fenton mechanism. Eur J Biochem. 1983;137:119-20.
    • (1983) Eur J Biochem , vol.137 , pp. 119-120
    • Samuni, A.1    Aronovitch, J.2    Godinger, D.3    Chevion, M.4    Czapski, G.5
  • 48
    • 0026578540 scopus 로고
    • Iron Induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation: No spin trapping evidence for the hydroxyl radical in iron-over loaded plasmas
    • 1312330 1:CAS:528:DyaK38XhsVyqurc%3D
    • Minetti M, Forte T, Soriani M, Quaresima V, Menditto A, Ferrari M. Iron Induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation: no spin trapping evidence for the hydroxyl radical in iron-over loaded plasmas. Biochem J. 1992;282:459-65.
    • (1992) Biochem J , vol.282 , pp. 459-465
    • Minetti, M.1    Forte, T.2    Soriani, M.3    Quaresima, V.4    Menditto, A.5    Ferrari, M.6
  • 49
    • 0029311228 scopus 로고
    • Ferrous ion detected in iron-overloaded cord blood plasma from preterm and term babies: Implication for oxidation stress
    • 7543335 1:CAS:528:DyaK28Xitleqt7g%3D
    • Berger TM, Mumby S, Gutteridge JMC. Ferrous ion detected in iron-overloaded cord blood plasma from preterm and term babies: implication for oxidation stress. Free Radic Res. 1995;22:555-9.
    • (1995) Free Radic Res , vol.22 , pp. 555-559
    • Berger, T.M.1    Mumby, S.2    Gutteridge, J.M.C.3
  • 50
    • 0029910233 scopus 로고    scopus 로고
    • Vitamin C: Antioxidant or pro-oxidant in vivo ?
    • 8902542 1:CAS:528:DyaK28XntVOiur8%3D
    • Halliwell B. Vitamin C: antioxidant or pro-oxidant in vivo ? Free Radic Res. 1996;25:439-54.
    • (1996) Free Radic Res , vol.25 , pp. 439-454
    • Halliwell, B.1
  • 51
    • 0029868538 scopus 로고    scopus 로고
    • Vitamin C driven free radicals generation from iron
    • Herbert V, Shaw S, Jayatileke E. Vitamin C driven free radicals generation from iron. J Nutr. 1996;126:1213-20.
    • (1996) J Nutr , vol.126 , pp. 1213-1220
    • Herbert, V.1    Shaw, S.2    Jayatileke, E.3
  • 52
    • 0034597751 scopus 로고    scopus 로고
    • Potential problems of ascorbic acid and iron supplementation: Pro-oxidant effect in vivo?
    • 11061989 1:CAS:528:DC%2BD3cXnslCqur0%3D
    • Proteggente AR, Rehman A, Halliwell B, Rice-Evans CA. Potential problems of ascorbic acid and iron supplementation: pro-oxidant effect in vivo? Biochem Biophys Res Commun. 2000;277:535-54053.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 535-54053
    • Proteggente, A.R.1    Rehman, A.2    Halliwell, B.3    Rice-Evans, C.A.4
  • 54
    • 0006489597 scopus 로고
    • Chemical composition of human serum and of the secretion of prostate and seminal vesicles
    • 1:CAS:528:DyaH38XivFGkuw%3D%3D
    • Huggins C, Scott WW, Heinen JH. Chemical composition of human serum and of the secretion of prostate and seminal vesicles. Am J Physiol. 1942;136:467-73.
    • (1942) Am J Physiol , vol.136 , pp. 467-473
    • Huggins, C.1    Scott, W.W.2    Heinen, J.H.3
  • 56
    • 0018052638 scopus 로고
    • Ascorbic acid turn over in animal and human tissue
    • (Silver Jubilee Volume)
    • Chinoy NJ. Ascorbic acid turn over in animal and human tissue. J Anim Morphol Physiol. 1978; (Silver Jubilee Volume):69-85.
    • (1978) J Anim Morphol Physiol , pp. 69-85
    • Chinoy, N.J.1
  • 57
    • 33748975122 scopus 로고
    • Structural changes in male reproductive organs and spermatozoa of scorbutic guinea-pigs
    • Chinoy MR, Sharma JD, Sanjeevan AG, Chinoy NJ. Structural changes in male reproductive organs and spermatozoa of scorbutic guinea-pigs. Proc Ind Natl Sci Acad. 1983;B49:628-35.
    • (1983) Proc Ind Natl Sci Acad , vol.49 , pp. 628-635
    • Chinoy, M.R.1    Sharma, J.D.2    Sanjeevan, A.G.3    Chinoy, N.J.4
  • 58
    • 0017356862 scopus 로고
    • Gonadal and plasma testosterone and cholesterol in scorbutic guinea-pigs
    • Gomes S, Odour OD, Bharaj B, Verjee ZH. Gonadal and plasma testosterone and cholesterol in scorbutic guinea-pigs. Int J Vit Nutr Res. 1977;47:75-80.
    • (1977) Int J Vit Nutr Res , vol.47 , pp. 75-80
    • Gomes, S.1    Odour, O.D.2    Bharaj, B.3    Verjee, Z.H.4
  • 59
    • 0017816790 scopus 로고
    • Beneficial or harmful effects of a large dose of vitamin C on the reproductive organs of the male rat depending upon the level of food intake
    • 1:CAS:528:DyaE1cXhtFGgu70%3D
    • Paul PK, Datta-Gupta PN. Beneficial or harmful effects of a large dose of vitamin C on the reproductive organs of the male rat depending upon the level of food intake. Ind J Exp Biol. 1978;16:18-21.
    • (1978) Ind J Exp Biol , vol.16 , pp. 18-21
    • Paul, P.K.1    Datta-Gupta, P.N.2
  • 60
    • 0023318380 scopus 로고
    • Effect of vitamin C deficiency on testicular structure in the guinea pig
    • 3681751 1:STN:280:DyaL1c%2Fmt1aksQ%3D%3D
    • Sapra M, Sharma P, Kothari LK. Effect of vitamin C deficiency on testicular structure in the guinea pig. J Postgrad Med. 1987;33:69-73.
    • (1987) J Postgrad Med , vol.33 , pp. 69-73
    • Sapra, M.1    Sharma, P.2    Kothari, L.K.3
  • 61
    • 2942521602 scopus 로고    scopus 로고
    • Role of antioxidants in treatment of male infertility
    • 15169573 1:CAS:528:DC%2BD2cXltlCrtLg%3D
    • Agarwal A. Role of antioxidants in treatment of male infertility. Reprod Biomed Online. 2004;8:616-27.
    • (2004) Reprod Biomed Online , vol.8 , pp. 616-627
    • Agarwal, A.1
  • 62
    • 70350337541 scopus 로고    scopus 로고
    • Ascorbic acid in human seminal plasma: Determination and its relationship to sperm quality
    • Abasalt H, Colagar Eisa T, Marzony. Ascorbic acid in human seminal plasma: determination and its relationship to sperm quality. J Clin Biochem Nutr. 2009;45(2):144-9.
    • (2009) J Clin Biochem Nutr , vol.45 , Issue.2 , pp. 144-149
    • Abasalt, H.1    Colagar Eisa, T.2    Marzony3
  • 63
    • 0037834778 scopus 로고    scopus 로고
    • Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility
    • 12801566
    • Saleh RA, Agarwal A, Nada EA, Tonsy MH, Sharma RK, Meyer A, et al. Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Fertil Steril. 2003;79:1597.
    • (2003) Fertil Steril , vol.79 , pp. 1597
    • Saleh, R.A.1    Agarwal, A.2    Nada, E.A.3    Tonsy, M.H.4    Sharma, R.K.5    Meyer, A.6
  • 64
    • 34547452613 scopus 로고    scopus 로고
    • Total antioxidant capacity of seminal plasma in fertile and infertile men
    • 16398363
    • Shi YC, Sun HM, Shang XJ, Zhu PY, Huang YF. Total antioxidant capacity of seminal plasma in fertile and infertile men. Zhonghua Nan Ke Xue. 2005;11:915-7.
    • (2005) Zhonghua Nan Ke Xue , vol.11 , pp. 915-917
    • Shi, Y.C.1    Sun, H.M.2    Shang, X.J.3    Zhu, P.Y.4    Huang, Y.F.5
  • 65
    • 39049189302 scopus 로고    scopus 로고
    • Correlation of total antioxidant capacity in seminal plasma with sperm motility of infertile men
    • 16970158 1:CAS:528:DC%2BD2sXhtlWhur3E
    • Shi YC, Shang XJ, Wang XL, Huang YF. Correlation of total antioxidant capacity in seminal plasma with sperm motility of infertile men. Zhonghua Nan Ke Xue. 2006;12:703-5.
    • (2006) Zhonghua Nan Ke Xue , vol.12 , pp. 703-705
    • Shi, Y.C.1    Shang, X.J.2    Wang, X.L.3    Huang, Y.F.4
  • 66
    • 0028238811 scopus 로고
    • Relationship of sperm parameters to levels of reactive oxygen species in semen specimens
    • 8201640 1:STN:280:DyaK2c3mtVGltA%3D%3D
    • Agarwal A, Ikemoto I, Loughlin KR. Relationship of sperm parameters to levels of reactive oxygen species in semen specimens. J Urol. 1994;152:107-10.
    • (1994) J Urol , vol.152 , pp. 107-110
    • Agarwal, A.1    Ikemoto, I.2    Loughlin, K.R.3
  • 68
    • 84864183901 scopus 로고    scopus 로고
    • Impact of oxidative stress on male infertility
    • 22779727 1:STN:280:DC%2BC38joslymsA%3D%3D
    • Hampl R, Drábková P, Kanďár R, Stěpán J. Impact of oxidative stress on male infertility. Ceska Gynekol. 2012;77(3):241-5.
    • (2012) Ceska Gynekol , vol.77 , Issue.3 , pp. 241-245
    • Hampl, R.1    Drábková, P.2    Kanďár, R.3    Stěpán, J.4
  • 70
    • 0026019517 scopus 로고
    • Determination of ascorbic acid in blood or serum and in seminal plasma using a simplified sample preparation and high performance liquid chromatography coupled with UV detection
    • 1:CAS:528:DyaK3MXit1Crtr0%3D
    • Patriarca M, Menditto A, Morisi G. Determination of ascorbic acid in blood or serum and in seminal plasma using a simplified sample preparation and high performance liquid chromatography coupled with UV detection. J Liq Chromatogr. 1991;14:297-312.
    • (1991) J Liq Chromatogr , vol.14 , pp. 297-312
    • Patriarca, M.1    Menditto, A.2    Morisi, G.3
  • 71
    • 33646178622 scopus 로고    scopus 로고
    • Oxidative stress, sperm survival and fertility control
    • 16412557 1:CAS:528:DC%2BD28XksVGjtrc%3D
    • Aitken RJ, Baker MA. Oxidative stress, sperm survival and fertility control. Mol Cell Endocrinol. 2006;250:66-9.
    • (2006) Mol Cell Endocrinol , vol.250 , pp. 66-69
    • Aitken, R.J.1    Baker, M.A.2
  • 72
    • 0033957023 scopus 로고    scopus 로고
    • Glutathione and hypotaurine in vitro: Effects on human sperm motility, DNA integrity and production of reactive oxygen species
    • 10640532 1:CAS:528:DC%2BD3cXhtVantL4%3D
    • Donnelly ET, McClure N, Lewis SE. Glutathione and hypotaurine in vitro: effects on human sperm motility, DNA integrity and production of reactive oxygen species. Mutagenesis. 2000;15:61-8.
    • (2000) Mutagenesis , vol.15 , pp. 61-68
    • Donnelly, E.T.1    McClure, N.2    Lewis, S.E.3
  • 73
    • 0343907222 scopus 로고    scopus 로고
    • Increased oxidative deoxyribonucleic acid damage in spermatozoa of infertile male patients
    • 9314926 1:STN:280:DyaK2svmtVGntg%3D%3D
    • Kodama H, Yamaguchi R, Fukuda J, Kasi H, Tanaka K. Increased oxidative deoxyribonucleic acid damage in spermatozoa of infertile male patients. Fertil Steril. 1997;68:519-24.
    • (1997) Fertil Steril , vol.68 , pp. 519-524
    • Kodama, H.1    Yamaguchi, R.2    Fukuda, J.3    Kasi, H.4    Tanaka, K.5
  • 74
    • 0032845484 scopus 로고    scopus 로고
    • The effect of ascorbate and alpha-tocopherol supplementation in vitro on DNA integrity and hydrogen peroxide induced DNA damage in human spermatozoa
    • 10473655 1:CAS:528:DyaK1MXmtlOjt74%3D
    • Donnelly E, McClure N, Lewis SEM. The effect of ascorbate and alpha-tocopherol supplementation in vitro on DNA integrity and hydrogen peroxide induced DNA damage in human spermatozoa. Mutagenesis. 1999;14:505-12.
    • (1999) Mutagenesis , vol.14 , pp. 505-512
    • Donnelly, E.1    McClure, N.2    Lewis, S.E.M.3
  • 75
    • 84883191528 scopus 로고    scopus 로고
    • The prophylactic effect of vitamin C on induced oxidative stress in rat testis following exposure to 900 MHz radio frequency wave generated by a BTS antenna model
    • doi: 10.3109/15368378.2012.735208
    • Jelodar G, Nazifi S, Akbari A. The prophylactic effect of vitamin C on induced oxidative stress in rat testis following exposure to 900 MHz radio frequency wave generated by a BTS antenna model. Electromagn Biol Med. 2013. doi: 10.3109/15368378.2012.735208.
    • (2013) Electromagn Biol Med
    • Jelodar, G.1    Nazifi, S.2    Akbari, A.3
  • 76
    • 0031760519 scopus 로고    scopus 로고
    • Human sperm motility and lipid peroxidation in different ascorbic acid concentrations: An invitro analysis
    • 9835946 1:CAS:528:DyaK1cXnvVOls7k%3D
    • Verma A, Kanwar KC. Human sperm motility and lipid peroxidation in different ascorbic acid concentrations: an invitro analysis. Andrologia. 1998;30:325-9.
    • (1998) Andrologia , vol.30 , pp. 325-329
    • Verma, A.1    Kanwar, K.C.2
  • 77
    • 0042565855 scopus 로고    scopus 로고
    • Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect
    • Henmi H, Endo T, Kitaiima Y, et al. Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect. Fertil Steril. 2002;80:459-61.
    • (2002) Fertil Steril , vol.80 , pp. 459-461
    • Henmi, H.1    Endo, T.2    Kitaiima, Y.3
  • 78
    • 84886371478 scopus 로고
    • Effect of ascorbic acid, nicotinic acid and thiamine on cholestolemia
    • Myasnikova IA. Effect of ascorbic acid, nicotinic acid and thiamine on cholestolemia. Voenno Morski Med Akad Leningrad. 1947;8:140.
    • (1947) Voenno Morski Med Akad Leningrad , vol.8 , pp. 140
    • Myasnikova, I.A.1
  • 79
    • 0015252403 scopus 로고
    • Raised ascorbic acid consumption in cholesterol fed guinea pigs
    • 1:CAS:528:DyaE38Xktlehsrw%3D
    • Ginter E, Zolch Z. Raised ascorbic acid consumption in cholesterol fed guinea pigs. Int J Vit Nutr Res. 1972;42:72.
    • (1972) Int J Vit Nutr Res , vol.42 , pp. 72
    • Ginter, E.1    Zolch, Z.2
  • 80
    • 0016154763 scopus 로고
    • Ascorbate-cholesterol-lecithin interactions factors of potential importance in pathogenesis of atherosclerosis
    • 4602980 1:CAS:528:DyaE2cXls1yjtrw%3D
    • Krumdieck C, Butterworth CE. Ascorbate-cholesterol-lecithin interactions factors of potential importance in pathogenesis of atherosclerosis. Am J Clin Nutr. 1974;27:866.
    • (1974) Am J Clin Nutr , vol.27 , pp. 866
    • Krumdieck, C.1    Butterworth, C.E.2
  • 81
    • 84885038700 scopus 로고
    • Metabolism of acetate in scorbutic guinea pigs
    • 13686556 1:CAS:528:DyaF3MXktl2ksw%3D%3D
    • Banerjee S, Gosh PK. Metabolism of acetate in scorbutic guinea pigs. Am J Physiol. 1960;199:1064.
    • (1960) Am J Physiol , vol.199 , pp. 1064
    • Banerjee, S.1    Gosh, P.K.2
  • 82
    • 0031081572 scopus 로고    scopus 로고
    • Effect of ascorbic acid on lipid profile and per-oxidation in hypercholestrolemic rabbits
    • 1:CAS:528:DyaK2sXhtVSjsr0%3D
    • Das S, Snehlata, Srivastava LK. Effect of ascorbic acid on lipid profile and per-oxidation in hypercholestrolemic rabbits. Nutr Res. 1997;17(2):231-41.
    • (1997) Nutr Res , vol.17 , Issue.2 , pp. 231-241
    • Das, S.1    Snehlata2    Srivastava, L.K.3
  • 83
    • 0014601483 scopus 로고
    • The effect of chronic hypovitaminosis C on the metabolism of cholesterol and atherogenesis in guinea pigs
    • 5364084 1:CAS:528:DyaE3cXoslKgtA%3D%3D
    • Ginter E, Babla J, Cerven J. The effect of chronic hypovitaminosis C on the metabolism of cholesterol and atherogenesis in guinea pigs. J Atheroscler Res. 1969;10:341.
    • (1969) J Atheroscler Res , vol.10 , pp. 341
    • Ginter, E.1    Babla, J.2    Cerven, J.3
  • 85
    • 85027929229 scopus 로고    scopus 로고
    • High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs
    • 20875184 1:CAS:528:DC%2BC3MXht1Snsg%3D%3D
    • Frikke-Schmidt H, Tveden-Nyborg P, Muusfeldt Birck M, Lykkesfeldt J. High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs. Br J Nutr. 2011;105:54-61.
    • (2011) Br J Nutr , vol.105 , pp. 54-61
    • Frikke-Schmidt, H.1    Tveden-Nyborg, P.2    Muusfeldt Birck, M.3    Lykkesfeldt, J.4
  • 86
    • 0023924710 scopus 로고
    • Effect of vitamin C administration on serum and aortic lipid profile of guinea pigs
    • Sharma P, Pramod J, Sharma PK, Chaturvedi SK, Kothari LK. Effect of vitamin C administration on serum and aortic lipid profile of guinea pigs. IJMR. 1988;87:28.
    • (1988) IJMR , vol.87 , pp. 28
    • Sharma, P.1    Pramod, J.2    Sharma, P.K.3    Chaturvedi, S.K.4    Kothari, L.K.5
  • 87
    • 0024200813 scopus 로고
    • Aggravation of cholesterol induced hyperlipidemia by chronic vitamin C deficiency: Experimental study in guinea pigs
    • Kothari LK, Sharma P. Aggravation of cholesterol induced hyperlipidemia by chronic vitamin C deficiency: experimental study in guinea pigs. Acta Biol Hung. 1988;39(1):4.
    • (1988) Acta Biol Hung , vol.39 , Issue.1 , pp. 4
    • Kothari, L.K.1    Sharma, P.2
  • 88
    • 84886362789 scopus 로고
    • Leucocyte ascorbic acid and blood lipids in normocholesterolemic men receiving different amounts of vitamin C
    • Vaney N, Sharma P, Pramod J, Varandami J, Kothari LK. Leucocyte ascorbic acid and blood lipids in normocholesterolemic men receiving different amounts of vitamin C. Vitaminologia. 1988;4:47-8.
    • (1988) Vitaminologia , vol.4 , pp. 47-48
    • Vaney, N.1    Sharma, P.2    Pramod, J.3    Varandami, J.4    Kothari, L.K.5
  • 89
    • 84885076016 scopus 로고    scopus 로고
    • Comparative study of vitamin C on serum lipid profile in healthy male and female human subjects
    • 1:CAS:528:DC%2BC38XhtlOlt7bE
    • Gaur GS, Dixit AK. Comparative study of vitamin C on serum lipid profile in healthy male and female human subjects. J Sci Res. 2012;4(3):775-81.
    • (2012) J Sci Res , vol.4 , Issue.3 , pp. 775-781
    • Gaur, G.S.1    Dixit, A.K.2
  • 90
    • 44149086390 scopus 로고    scopus 로고
    • Vitamin C supplementation lowers serum low-density lipoprotein cholesterol and triglycerides: A meta-analysis of 13 randomized controlled trials
    • Marc P, McRae. Vitamin C supplementation lowers serum low-density lipoprotein cholesterol and triglycerides: a meta-analysis of 13 randomized controlled trials. JCM. 2008;7(2):548-81.
    • (2008) JCM , vol.7 , Issue.2 , pp. 548-581
    • Marc, P.1    McRae2
  • 91
    • 0025671772 scopus 로고
    • Serum ascorbic acid and HDL cholesterol in a healthy elderly Japanese population
    • 1:STN:280:DyaK3MzjtFOntg%3D%3D
    • Itoh R, Yamada K, Oka J, Echizen H, Suyama Y, Murakami K. Serum ascorbic acid and HDL cholesterol in a healthy elderly Japanese population. Int J Vit Nutr Res. 1990;60(4):360-5.
    • (1990) Int J Vit Nutr Res , vol.60 , Issue.4 , pp. 360-365
    • Itoh, R.1    Yamada, K.2    Oka, J.3    Echizen, H.4    Suyama, Y.5    Murakami, K.6
  • 92
    • 0026530425 scopus 로고
    • Effects of vitamin C on high-density lipoprotein cholesterol and blood pressure
    • 1578088 1:CAS:528:DyaK38XkvV2hur0%3D
    • Jacques PF. Effects of vitamin C on high-density lipoprotein cholesterol and blood pressure. J Am Coll Nutr. 1992;11(2):139-44.
    • (1992) J Am Coll Nutr , vol.11 , Issue.2 , pp. 139-144
    • Jacques, P.F.1
  • 94
    • 0028815135 scopus 로고
    • Effect of vitamin C supplementation on lipoprotein cholesterol, apolipoprotein, and triglyceride concentrations
    • 7728285 1:STN:280:DyaK2M3ksFCrsQ%3D%3D
    • Jacques PF, Sulsky SI, Perrone GE, Jenner J, Schaefer EJ. Effect of vitamin C supplementation on lipoprotein cholesterol, apolipoprotein, and triglyceride concentrations. Ann Epidemiol. 1995;5(1):52-9.
    • (1995) Ann Epidemiol , vol.5 , Issue.1 , pp. 52-59
    • Jacques, P.F.1    Sulsky, S.I.2    Perrone, G.E.3    Jenner, J.4    Schaefer, E.J.5
  • 95
    • 0027105051 scopus 로고
    • The relationship between dietary ascorbic acid intake and serum lipid concentration in the aged
    • 1494242 1:STN:280:DyaK3s7ls1WktA%3D%3D
    • Okamoto K. The relationship between dietary ascorbic acid intake and serum lipid concentration in the aged. Nihon Ronen Igakkai Zasshi. 1992;29(12):908-11.
    • (1992) Nihon Ronen Igakkai Zasshi , vol.29 , Issue.12 , pp. 908-911
    • Okamoto, K.1
  • 96
    • 0031781522 scopus 로고    scopus 로고
    • Relation of serum ascorbic acid to serum lipids and lipoproteins in US adults
    • 9627911 1:CAS:528:DyaK1cXktFeksr0%3D
    • Simon JA, Hudes ES. Relation of serum ascorbic acid to serum lipids and lipoproteins in US adults. J Am Coll Nutr. 1998;17(3):250-5.
    • (1998) J Am Coll Nutr , vol.17 , Issue.3 , pp. 250-255
    • Simon, J.A.1    Hudes, E.S.2
  • 97
    • 0001706149 scopus 로고
    • A prospective study of vitamin C and incidence of coronary heart disease in women
    • Manson JE, Stampfer MJ, Willett WC, et al. A prospective study of vitamin C and incidence of coronary heart disease in women. Circulation. 1982;85:865-75.
    • (1982) Circulation , vol.85 , pp. 865-875
    • Manson, J.E.1    Stampfer, M.J.2    Willett, W.C.3
  • 98
    • 0028283939 scopus 로고
    • Antioxidant vitamin intake and coronary mortality in a longitudinal population study
    • 8209876 1:STN:280:DyaK2c3ntVeltg%3D%3D
    • Knekt P, Reunanen A, Jarvinen R, Seppanen R, Heliovaara M, Aromaa A. Antioxidant vitamin intake and coronary mortality in a longitudinal population study. Am J Epidemiol. 1994;139:1180-9.
    • (1994) Am J Epidemiol , vol.139 , pp. 1180-1189
    • Knekt, P.1    Reunanen, A.2    Jarvinen, R.3    Seppanen, R.4    Heliovaara, M.5    Aromaa, A.6
  • 100
    • 0026576932 scopus 로고
    • Vitamin C intake and mortality among a sample of the United States population
    • 1591317 1:STN:280:DyaK383ntlKrug%3D%3D
    • Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology. 1992;3:194-202.
    • (1992) Epidemiology , vol.3 , pp. 194-202
    • Enstrom, J.E.1    Kanim, L.E.2    Klein, M.A.3
  • 101
    • 2842563216 scopus 로고
    • Effect of age and sex on serum and leucocyte ascorbic acid levels in normal human subjects
    • Pramod J, Sharma P, Kothari LK. Effect of age and sex on serum and leucocyte ascorbic acid levels in normal human subjects. Vitaminologia. 1986;2:93-100.
    • (1986) Vitaminologia , vol.2 , pp. 93-100
    • Pramod, J.1    Sharma, P.2    Kothari, L.K.3
  • 102
    • 0024257817 scopus 로고
    • Influence of age and vitamin C status on serum cholesterol
    • 1:STN:280:DyaL1M7jvVyisA%3D%3D
    • Kothari LK, Pramod J, Sharma P, Chaturvedi SK. Influence of age and vitamin C status on serum cholesterol. IJE. 1988;17(4):929-30.
    • (1988) IJE , vol.17 , Issue.4 , pp. 929-930
    • Kothari, L.K.1    Pramod, J.2    Sharma, P.3    Chaturvedi, S.K.4
  • 103
    • 0029045975 scopus 로고
    • Vitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people
    • 1:STN:280:DyaK2MzgslegsQ%3D%3D
    • Gale CR, Martyn CN, Winter PD, Cooper C. Vitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people. Br Med J. 1995;310:1563-6.
    • (1995) Br Med J , vol.310 , pp. 1563-1566
    • Gale, C.R.1    Martyn, C.N.2    Winter, P.D.3    Cooper, C.4
  • 104
    • 0033612841 scopus 로고    scopus 로고
    • Role of antioxidant vitamins in prevention of cardiovascular disease
    • 1:STN:280:DyaK1Mzptleqsw%3D%3D
    • Ness A, Egger M, Davey-Smith G. Role of antioxidant vitamins in prevention of cardiovascular disease. Br Med J. 1999;319:577-9.
    • (1999) Br Med J , vol.319 , pp. 577-579
    • Ness, A.1    Egger, M.2    Davey-Smith, G.3
  • 105
    • 0024992023 scopus 로고
    • Role of oxidative modified LDL in atherosclerosis
    • 2227530 1:CAS:528:DyaK3MXltFWks7Y%3D
    • Steinbrecher UP, Zhang H, Lougheed M. Role of oxidative modified LDL in atherosclerosis. Free Radic Biol Med. 1990;9:155-68.
    • (1990) Free Radic Biol Med , vol.9 , pp. 155-168
    • Steinbrecher, U.P.1    Zhang, H.2    Lougheed, M.3
  • 106
    • 0004446569 scopus 로고    scopus 로고
    • Vitamin C as an antiatherogen: Mechanism of action
    • L. Packer J. Fuchs (eds) Marcel and Dekker Inc New York
    • Frei B. Vitamin C as an antiatherogen: mechanism of action. In: Packer L, Fuchs J, editors. Vitamin C in health and disease. New York: Marcel and Dekker Inc; 1997. p. 163-82.
    • (1997) Vitamin C in Health and Disease , pp. 163-182
    • Frei, B.1
  • 108
    • 0026584195 scopus 로고
    • In vitro lipid peroxidation of human serum catalyzed by copper ion: Antioxidant rather than prooxidant role of ascorbate
    • Dasgupta A, Zdunek T. In vitro lipid peroxidation of human serum catalyzed by copper ion: antioxidant rather than prooxidant role of ascorbate. Life Sci. 1992;50:2875-82.
    • (1992) Life Sci , vol.50 , pp. 2875-2882
    • Dasgupta, A.1    Zdunek, T.2
  • 109
    • 0001218860 scopus 로고
    • Ascorbate is an outstanding antioxidant in human blood plasma
    • 2762330 1:CAS:528:DyaL1MXltlWrsb4%3D
    • Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA. 1989;86:6377-81.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6377-6381
    • Frei, B.1    England, L.2    Ames, B.N.3
  • 110
    • 0030928673 scopus 로고    scopus 로고
    • Both intracellular and extracellular vitamin C inhibit atherogenic modification of LDL by human vascular endothelial cells
    • 1:CAS:528:DyaK2sXmtFKisbY%3D
    • Martin A, Frei B. Both intracellular and extracellular vitamin C inhibit atherogenic modification of LDL by human vascular endothelial cells. Atheroscler Thromb Vasc Biol. 1997;17:1583-90.
    • (1997) Atheroscler Thromb Vasc Biol , vol.17 , pp. 1583-1590
    • Martin, A.1    Frei, B.2
  • 111
    • 33747833778 scopus 로고    scopus 로고
    • Role of ascorbic acid on in vitro oxidation of low-density lipoprotein derived from hypercholesterolemic patients
    • 16701604 1:CAS:528:DC%2BD28XovVSksb8%3D
    • Das S, Snehlata DN, Srivastava LM. Role of ascorbic acid on in vitro oxidation of low-density lipoprotein derived from hypercholesterolemic patients. Clin Chim Acta. 2006;372(1-2):202-5.
    • (2006) Clin Chim Acta , vol.372 , Issue.1-2 , pp. 202-205
    • Das, S.1    Snehlata, D.N.2    Srivastava, L.M.3
  • 112
    • 84872152437 scopus 로고    scopus 로고
    • Antioxidant effects of vitamins C and e on the low-density lipoprotein oxidation mediated by myeloperoxidase
    • 1:CAS:528:DC%2BC3sXktVGlsbo%3D
    • Shariat SZAS, Mostafavi SA, Khakpour F. Antioxidant effects of vitamins C and E on the low-density lipoprotein oxidation mediated by myeloperoxidase. Iran Biomed J. 2013;17(1):22-8.
    • (2013) Iran Biomed J , vol.17 , Issue.1 , pp. 22-28
    • Shariat, S.1    Mostafavi, S.A.2    Khakpour, F.3
  • 113
    • 0028018112 scopus 로고
    • Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo
    • 7519784 1:CAS:528:DyaK2cXltlartrY%3D
    • Lehr HA, Frei B, Arfors KE. Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc Natl Acad Sci USA. 1994;91:7688-92.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7688-7692
    • Lehr, H.A.1    Frei, B.2    Arfors, K.E.3
  • 114
    • 0030926826 scopus 로고    scopus 로고
    • Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking
    • 9153277 1:CAS:528:DyaK2sXjsVGqsbk%3D
    • Lehr HA, Weyrich AS, Saetzler RK, Jurek A, Arfors KE, Zimmerman GA, et al. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest. 1997;99:2358-64.
    • (1997) J Clin Invest , vol.99 , pp. 2358-2364
    • Lehr, H.A.1    Weyrich, A.S.2    Saetzler, R.K.3    Jurek, A.4    Arfors, K.E.5    Zimmerman, G.A.6
  • 115
    • 0028957404 scopus 로고
    • Protection from oxidized LDL induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin e
    • Lehr HA, Frei B, Olofsson AM, Carew TE, Arfors KE. Protection from oxidized LDL induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin E. Circulation. 1995;91:1552-3.
    • (1995) Circulation , vol.91 , pp. 1552-1553
    • Lehr, H.A.1    Frei, B.2    Olofsson, A.M.3    Carew, T.E.4    Arfors, K.E.5
  • 116
    • 0027291525 scopus 로고
    • Protective effect of lipophilic derivatives of ascorbic acid on lipid peroxide-induced endothelial injury
    • 8323284 1:STN:280:DyaK3szht1Sjsg%3D%3D
    • Kaneko T, Kaji K, Mastuo M. Protective effect of lipophilic derivatives of ascorbic acid on lipid peroxide-induced endothelial injury. Arch Biochem Biophys. 1993;304:176-80.
    • (1993) Arch Biochem Biophys , vol.304 , pp. 176-180
    • Kaneko, T.1    Kaji, K.2    Mastuo, M.3
  • 117
    • 38649133871 scopus 로고    scopus 로고
    • Alpha-lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells
    • 18026819 1:CAS:528:DC%2BD1cXhtFahtrg%3D
    • Sabharwal AK, May JM. Alpha-lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells. Mol Cell Biochem. 2008;309:125-32.
    • (2008) Mol Cell Biochem , vol.309 , pp. 125-132
    • Sabharwal, A.K.1    May, J.M.2
  • 118
    • 0030859382 scopus 로고    scopus 로고
    • The effect of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with low or high cholesterol levels
    • 9329641 1:CAS:528:DyaK2sXmvFCru7w%3D
    • Anderson D, Phillips BJ, Yu T, Edwards AJ, Ayesh R, Butterworth KR. The effect of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with low or high cholesterol levels. Environ Mol Mutagen. 1997;30:161-74.
    • (1997) Environ Mol Mutagen , vol.30 , pp. 161-174
    • Anderson, D.1    Phillips, B.J.2    Yu, T.3    Edwards, A.J.4    Ayesh, R.5    Butterworth, K.R.6
  • 119
    • 0030053223 scopus 로고    scopus 로고
    • Effect ascorbate supplementation on low density lipoprotein oxidation in smokers
    • 8808491 1:CAS:528:DyaK2MXpslGrtrk%3D
    • Fuller CJ, Grundy SM, Norkus EP, Jialal I. Effect ascorbate supplementation on low density lipoprotein oxidation in smokers. Atherosclerosis. 1996;119:139-50.
    • (1996) Atherosclerosis , vol.119 , pp. 139-150
    • Fuller, C.J.1    Grundy, S.M.2    Norkus, E.P.3    Jialal, I.4
  • 120
    • 1842404769 scopus 로고    scopus 로고
    • Effect of supplementation of smoking men with plain or slow release ascorbic acid on lipoprotein oxidation
    • 9076405 1:CAS:528:DyaK1cXktFentQ%3D%3D
    • Nyyssonen K, Poulsen HE, Hayn M, Agerbo P, Porkkalo Sarataho E, Kaikkonen J, et al. Effect of supplementation of smoking men with plain or slow release ascorbic acid on lipoprotein oxidation. Eur J Clin Nutr. 1997;51:154-63.
    • (1997) Eur J Clin Nutr , vol.51 , pp. 154-163
    • Nyyssonen, K.1    Poulsen, H.E.2    Hayn, M.3    Agerbo, P.4    Porkkalo Sarataho, E.5    Kaikkonen, J.6
  • 121
    • 0030747451 scopus 로고    scopus 로고
    • The effect of ascorbic acid on plasma lipids and oxidisability of LDL in male smokers
    • 9234031 1:CAS:528:DyaK1cXns1KgtQ%3D%3D
    • Samman S, Brown AJ, Beltran C, Singh S. The effect of ascorbic acid on plasma lipids and oxidisability of LDL in male smokers. Eur J Clin Nutr. 1997;51:472-7.
    • (1997) Eur J Clin Nutr , vol.51 , pp. 472-477
    • Samman, S.1    Brown, A.J.2    Beltran, C.3    Singh, S.4
  • 122
    • 0030851336 scopus 로고    scopus 로고
    • The effects of pharmacological supplementation with vitamin C on low density lipoprotein oxidation
    • 9241103 1:CAS:528:DyaK2sXltlKjs7k%3D
    • Wen Y, Cooke T, Feely J. The effects of pharmacological supplementation with vitamin C on low density lipoprotein oxidation. Br J Clin Pharmacol. 1997;44:94-7.
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 94-97
    • Wen, Y.1    Cooke, T.2    Feely, J.3
  • 123
    • 0033977482 scopus 로고    scopus 로고
    • Vitamin C prevents the acute atherogenic effects of passive smoking
    • Valkonen MM, Kuusi T. Vitamin C prevents the acute atherogenic effects of passive smoking. Free Radic Biol Med. 2000;28(3):3-428.
    • (2000) Free Radic Biol Med , vol.28 , Issue.3 , pp. 3-428
    • Valkonen, M.M.1    Kuusi, T.2
  • 124
    • 0033040739 scopus 로고    scopus 로고
    • Does vitamin C act as pro-oxidant under physiological conditions?
    • Carr AC, Frei B. Does vitamin C act as pro-oxidant under physiological conditions? FASEB J. 1999;13:1007-24.
    • (1999) FASEB J. , vol.13 , pp. 1007-1024
    • Carr, A.C.1    Frei, B.2
  • 125
    • 77957556759 scopus 로고    scopus 로고
    • Oxidized LDL up-regulates the ascorbic acid transporter SVCT2 in endothelial cells
    • 1:CAS:528:DC%2BC3cXhtFOktb3L
    • May JM, Li L, Qu ZC. Oxidized LDL up-regulates the ascorbic acid transporter SVCT2 in endothelial cells. ZC Mol Cell Biochem. 2010;343(12):217-22.
    • (2010) ZC Mol Cell Biochem , vol.343 , Issue.12 , pp. 217-222
    • May, J.M.1    Li, L.2    Qu, Z.C.3
  • 126
    • 0034949468 scopus 로고    scopus 로고
    • Iron loading and large doses of intravenous ascorbic acid promote lipid peroxidation in whole serum in guinea pigs
    • 11430772 1:CAS:528:DC%2BD3MXlsVarsbk%3D
    • Kapsokefalou M, Miller DD. Iron loading and large doses of intravenous ascorbic acid promote lipid peroxidation in whole serum in guinea pigs. Br J Nutr. 2001;85:681-7.
    • (2001) Br J Nutr , vol.85 , pp. 681-687
    • Kapsokefalou, M.1    Miller, D.D.2
  • 128
    • 0020694002 scopus 로고
    • Characterization of the aortic collagens in guinea pigs with chronic vitamin C deficiency
    • 6847747 1:CAS:528:DyaL3sXhsVaht7s%3D
    • Ginter E, Adama M. Characterization of the aortic collagens in guinea pigs with chronic vitamin C deficiency. Atherosclerosis. 1983;46(3):369-73.
    • (1983) Atherosclerosis , vol.46 , Issue.3 , pp. 369-373
    • Ginter, E.1    Adama, M.2
  • 130
    • 0028957404 scopus 로고
    • Protection from oxidized LDL induced leukocyte adhesion to microvascular and macrovascular endothelium in-vivo by vitamin C but not by vitamin e
    • 7867194 1:CAS:528:DyaK2MXkvF2ks7c%3D
    • Lehr HA. Protection from oxidized LDL induced leukocyte adhesion to microvascular and macrovascular endothelium in-vivo by vitamin C but not by vitamin E. Circulation. 1995;91:1525-32.
    • (1995) Circulation , vol.91 , pp. 1525-1532
    • Lehr, H.A.1
  • 131
    • 0029995285 scopus 로고    scopus 로고
    • Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers
    • 8608614 1:CAS:528:DyaK28XislGmurs%3D
    • Weber C. Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers. Circulation. 1996;93:1488-92.
    • (1996) Circulation , vol.93 , pp. 1488-1492
    • Weber, C.1
  • 132
    • 0037177206 scopus 로고    scopus 로고
    • Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic acid
    • 11914259 1:CAS:528:DC%2BD38XjsVyrtbk%3D
    • Nakata Y, Maeda N. Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic acid. Circulation. 2002;105:1485-90.
    • (2002) Circulation , vol.105 , pp. 1485-1490
    • Nakata, Y.1    Maeda, N.2
  • 133
    • 0016275402 scopus 로고
    • The orthomolecular treatment of cancer. II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer
    • 4430016 1:STN:280:DyaE2M%2FjslKquw%3D%3D
    • Cameron E, Campbell A. The orthomolecular treatment of cancer. II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer. Chem Biol Interact. 1974;9:285-315.
    • (1974) Chem Biol Interact , vol.9 , pp. 285-315
    • Cameron, E.1    Campbell, A.2
  • 134
    • 0006171777 scopus 로고
    • Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer
    • 1068480 1:CAS:528:DyaE28XlvVKku7k%3D
    • Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA. 1976;73:3685-9.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3685-3689
    • Cameron, E.1    Pauling, L.2
  • 135
    • 0012375577 scopus 로고
    • Supplemental ascorbate in the supportive treatment of cancer: Re-evaluation of prolongation of survival times in terminal human cancer
    • 279931 1:STN:280:DyaE1M%2Fjtlyktw%3D%3D
    • Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: re-evaluation of prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA. 1978;75:4538-42.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4538-4542
    • Cameron, E.1    Pauling, L.2
  • 136
    • 0020006414 scopus 로고
    • Prolongation of survival times of terminal cancer patients by administration of large doses of ascorbate
    • Murata A, Morishige F, Yamaguchi H. Prolongation of survival times of terminal cancer patients by administration of large doses of ascorbate. Int J Vit Nutr Res. 1982;2/23:103-13.
    • (1982) Int J Vit Nutr Res , vol.2-23 , pp. 103-113
    • Murata, A.1    Morishige, F.2    Yamaguchi, H.3
  • 137
    • 0026077980 scopus 로고
    • Vitamin C and cancer prevention: The epidemiologic evidence
    • 1985398 1:STN:280:DyaK3M%2FptVShtA%3D%3D
    • Block G. Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr. 1991;53(1):270S-82S.
    • (1991) Am J Clin Nutr , vol.53 , Issue.1
    • Block, G.1
  • 138
    • 0025790311 scopus 로고
    • Epidemiologic evidence regarding vitamin C and cancer
    • 1962588 1:STN:280:DyaK38%2FnsVChsQ%3D%3D
    • Block G. Epidemiologic evidence regarding vitamin C and cancer. Am J Clin Nutr. 1991;54(6):1310S.
    • (1991) Am J Clin Nutr , vol.54 , Issue.6
    • Block, G.1
  • 139
    • 0032087594 scopus 로고    scopus 로고
    • Ascorbic acid in the prevention and treatment of cancer
    • 9630735 1:STN:280:DyaK1czjtFymsA%3D%3D
    • Head KA. Ascorbic acid in the prevention and treatment of cancer. Altern Med Rev. 1998;3(3):174-86.
    • (1998) Altern Med Rev , vol.3 , Issue.3 , pp. 174-186
    • Head, K.A.1
  • 140
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • 1408943 1:STN:280:DyaK3s%2FislGnsQ%3D%3D
    • Block G, Patterson B, Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer. 1992;18:1-29.
    • (1992) Nutr Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 141
    • 0030411296 scopus 로고    scopus 로고
    • Vegetables, fruit, and cancer prevention: A review
    • 8841165 1:STN:280:DyaK28vjvVygsg%3D%3D
    • Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc. 1996;96:1027-39.
    • (1996) J Am Diet Assoc , vol.96 , pp. 1027-1039
    • Steinmetz, K.A.1    Potter, J.D.2
  • 142
  • 143
    • 0035799105 scopus 로고    scopus 로고
    • Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: A prospective population study: European prospective investigation into cancer and nutrition
    • 11247548 1:CAS:528:DC%2BD3MXhslyksb4%3D
    • Khaw KT, Bingham S, Welch A, Luben R, Wareham N, Oakes S, Day N. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study: European prospective investigation into cancer and nutrition. Lancet. 2001;357:657-63.
    • (2001) Lancet , vol.357 , pp. 657-663
    • Khaw, K.T.1    Bingham, S.2    Welch, A.3    Luben, R.4    Wareham, N.5    Oakes, S.6    Day, N.7
  • 144
    • 0030018520 scopus 로고    scopus 로고
    • Intake of vitamins A, C, and e and postmenopausal breast cancer: The Iowa Women's Health Study
    • 8678048 1:STN:280:DyaK283otlSlsw%3D%3D
    • Kushi LH, Fee RM, Sellers TA, Zheng W, Folsom AR. Intake of vitamins A, C, and E and postmenopausal breast cancer: The Iowa Women's Health Study. Am J Epidemiol. 1996;144(2):165-74.
    • (1996) Am J Epidemiol , vol.144 , Issue.2 , pp. 165-174
    • Kushi, L.H.1    Fee, R.M.2    Sellers, T.A.3    Zheng, W.4    Folsom, A.R.5
  • 146
    • 0032087594 scopus 로고    scopus 로고
    • Ascorbic acid in prevention and treatment of cancer
    • Kathleen A. Ascorbic acid in prevention and treatment of cancer. Altern Med Rev. 1988;3(3):174-86.
    • (1988) Altern Med Rev , vol.3 , Issue.3 , pp. 174-186
    • Kathleen, A.1
  • 147
    • 26444521256 scopus 로고    scopus 로고
    • Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
    • 16157892 1:CAS:528:DC%2BD2MXhtVygtr%2FP
    • Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, et al. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc Natl Acad Sci USA. 2005;102:13604-9.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13604-13609
    • Chen, Q.1    Espey, M.G.2    Krishna, M.C.3    Mitchell, J.B.4    Corpe, C.P.5    Buettner, G.R.6
  • 148
    • 77956995087 scopus 로고    scopus 로고
    • Vitamin C and cancer: What can we conclude - 1, 609 patients and 33 years later?
    • 20799507
    • Cabanillas F. Vitamin C and cancer: what can we conclude - 1, 609 patients and 33 years later? P R Health Sci J. 2010;29(3):215-7.
    • (2010) P R Health Sci J , vol.29 , Issue.3 , pp. 215-217
    • Cabanillas, F.1
  • 149
    • 84855541345 scopus 로고    scopus 로고
    • Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice
    • 22217712 1:CAS:528:DC%2BC38XivVaqt7c%3D
    • Cha J, Roomi MW, Ivanov V, Kalinovsky T, Niedzwiecki A, Rath M. Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice. Exp Oncol. 2011;33(4):226-30.
    • (2011) Exp Oncol , vol.33 , Issue.4 , pp. 226-230
    • Cha, J.1    Roomi, M.W.2    Ivanov, V.3    Kalinovsky, T.4    Niedzwiecki, A.5    Rath, M.6
  • 150
    • 84873683033 scopus 로고    scopus 로고
    • Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice
    • 23175106 1:CAS:528:DC%2BC3sXhsVWntrw%3D
    • Cha J, Roomi MW, Ivanov V, Kalinovsky T, Niedzwiecki A, Rath M. Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice. Int J Oncol. 2013;42(1):55-64.
    • (2013) Int J Oncol , vol.42 , Issue.1 , pp. 55-64
    • Cha, J.1    Roomi, M.W.2    Ivanov, V.3    Kalinovsky, T.4    Niedzwiecki, A.5    Rath, M.6
  • 151
    • 33645573747 scopus 로고    scopus 로고
    • High-dose vitamin C therapy: Renewed hope or false promise?
    • 16567756
    • Assouline S, Miller WH. High-dose vitamin C therapy: renewed hope or false promise? CMAJ. 2006;174:956-7.
    • (2006) CMAJ , vol.174 , pp. 956-957
    • Assouline, S.1    Miller, W.H.2
  • 152
    • 33847110692 scopus 로고    scopus 로고
    • Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration
    • 17297243 1:CAS:528:DC%2BD2sXjs1ymsLo%3D
    • Yeom CH, Jung GC, Song KJ. Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration. J Korean Med Sci. 2007;22:7-11.
    • (2007) J Korean Med Sci , vol.22 , pp. 7-11
    • Yeom, C.H.1    Jung, G.C.2    Song, K.J.3
  • 153
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • 15111519
    • Wild SH, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.H.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 154
    • 75149130955 scopus 로고    scopus 로고
    • American Diabetes Association Diagnosis and classification of diabetes mellitus
    • American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33:S62.
    • (2010) Diabetes Care , vol.33
  • 155
    • 84857084078 scopus 로고    scopus 로고
    • Chronic diabetic complications in Africa
    • Tesfaye S, Gill G. Chronic diabetic complications in Africa. Afr J Diabetes Med. 2011;19:4-8.
    • (2011) Afr J Diabetes Med , vol.19 , pp. 4-8
    • Tesfaye, S.1    Gill, G.2
  • 158
    • 0034939115 scopus 로고    scopus 로고
    • The role of oxidative stress in the onset and progression of diabetes and its complications: A summary of a Congress Series sponsored by UNESCO MCBN, the American Diabetes Association and the German Diabetes Society
    • 11424232 1:CAS:528:DC%2BD3MXlslOhurs%3D
    • Rosen P, Nawroth PP, King G, Moller W, Tritschler HJ, Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab Res Rev. 2001;17:189-912.
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 189-912
    • Rosen, P.1    Nawroth, P.P.2    King, G.3    Moller, W.4    Tritschler, H.J.5    Packer, L.6
  • 159
    • 49449090919 scopus 로고    scopus 로고
    • Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus: The European prospective investigation of cancer - Norfolk prospective study
    • 18663161
    • Harding AH, Wareham NJ, Bingham SA, Khaw K, Luben R, Welch A, et al. Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus: the European prospective investigation of cancer - Norfolk prospective study. Arch Intern Med. 2008;168(14):1493-9.
    • (2008) Arch Intern Med , vol.168 , Issue.14 , pp. 1493-1499
    • Harding, A.H.1    Wareham, N.J.2    Bingham, S.A.3    Khaw, K.4    Luben, R.5    Welch, A.6
  • 161
    • 0030797118 scopus 로고    scopus 로고
    • Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin-dependent diabetes mellitus
    • 9229228 1:STN:280:DyaK2szntlWktw%3D%3D
    • Maxwell SR, Thomason H, Sandler D, Leguen C, Baxter MA, Thorpe GH, et al. Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin-dependent diabetes mellitus. Eur J Clin Invest. 1997;27(6):484-90.
    • (1997) Eur J Clin Invest , vol.27 , Issue.6 , pp. 484-490
    • Maxwell, S.R.1    Thomason, H.2    Sandler, D.3    Leguen, C.4    Baxter, M.A.5    Thorpe, G.H.6
  • 162
    • 84861590027 scopus 로고    scopus 로고
    • Antioxidant status of type 2 diabetic patients in Port Harcourt, Nigeria
    • 22437091 1:STN:280:DC%2BC38vosVCltg%3D%3D
    • Odum EP, Ejilemele AA, Wakwe VC. Antioxidant status of type 2 diabetic patients in Port Harcourt, Nigeria. Niger J Clin Pract. 2012;15(1):55-8.
    • (2012) Niger J Clin Pract , vol.15 , Issue.1 , pp. 55-58
    • Odum, E.P.1    Ejilemele, A.A.2    Wakwe, V.C.3
  • 163
    • 82455212502 scopus 로고    scopus 로고
    • Effect of vitamin C supplementation on postprandial oxidative stress and lipid profile in type 2 diabetic patients
    • 22518934 1:CAS:528:DC%2BC38XmvFaqt78%3D
    • Mazloom Z, Hejazi N, Dabbaghmanesh MH, Tabatabaei HR, Ahmadi A, Ansar H. Effect of vitamin C supplementation on postprandial oxidative stress and lipid profile in type 2 diabetic patients. Pak J Biol Sci. 2011;14(19):900-4.
    • (2011) Pak J Biol Sci , vol.14 , Issue.19 , pp. 900-904
    • Mazloom, Z.1    Hejazi, N.2    Dabbaghmanesh, M.H.3    Tabatabaei, H.R.4    Ahmadi, A.5    Ansar, H.6
  • 164
    • 14944359744 scopus 로고    scopus 로고
    • Oxidative stress in metabolic syndrome
    • 23105513 1:CAS:528:DC%2BD2MXislagt78%3D
    • Sharma P, Mishra S, Ajmera P, Mathur S. Oxidative stress in metabolic syndrome. Indian J Clin Biochem. 2005;20(1):145-9.
    • (2005) Indian J Clin Biochem , vol.20 , Issue.1 , pp. 145-149
    • Sharma, P.1    Mishra, S.2    Ajmera, P.3    Mathur, S.4
  • 165
    • 79958863527 scopus 로고    scopus 로고
    • Dietary vitamin C and e modulates oxidative stress induced-kidney and lens injury in diabetic aged male rats through modulating glucose homeostasis and antioxidant systems
    • 21416480
    • Özkaya D, Naziroǧlu M, Armaǧan A, Demirel A, Köroglu BK, Çolakoǧlu N, et al. Dietary vitamin C and E modulates oxidative stress induced-kidney and lens injury in diabetic aged male rats through modulating glucose homeostasis and antioxidant systems. Cell Biochem Funct. 2011;29(4):287-93.
    • (2011) Cell Biochem Funct , vol.29 , Issue.4 , pp. 287-293
    • Özkaya, D.1    Naziroǧlu, M.2    Armaǧan, A.3    Demirel, A.4    Köroglu, B.K.5    Çolakoǧlu, N.6
  • 166
    • 84864321923 scopus 로고    scopus 로고
    • Dietary vitamin C and e modulates antioxidant levels in blood, brain, liver, muscle, and testes in diabetic aged rats
    • Naziroǧlu M, Butterworth PJ, Sonmez TT. Dietary vitamin C and E modulates antioxidant levels in blood, brain, liver, muscle, and testes in diabetic aged rats. Int J Vit Nutr Res. 2011;81(6):347-57.
    • (2011) Int J Vit Nutr Res , vol.81 , Issue.6 , pp. 347-357
    • Naziroǧlu, M.1    Butterworth, P.J.2    Sonmez, T.T.3
  • 167
    • 84866170786 scopus 로고    scopus 로고
    • Correlations between endothelial functions and ROS detection in diabetic microvascular wall: Early and late ascorbic acid supplementation
    • 22690337
    • Sridulyakul P, Wongeak-in N, Patumraj S. Correlations between endothelial functions and ROS detection in diabetic microvascular wall: early and late ascorbic acid supplementation. Int J Vasc Med. 2012;2012:709695.
    • (2012) Int J Vasc Med , vol.2012 , pp. 709695
    • Sridulyakul, P.1    Wongeak-In, N.2    Patumraj, S.3
  • 168
    • 84870058776 scopus 로고    scopus 로고
    • Ascorbic acid blocks hyperglycaemic impairment of endothelial function in adolescents with type 1 diabetes
    • 22925199 1:CAS:528:DC%2BC3sXhvFGktLs%3D
    • Hoffman RP, Dye AS, Bauer JA. Ascorbic acid blocks hyperglycaemic impairment of endothelial function in adolescents with type 1 diabetes. Pediatr Diabetes. 2012;13(8):607-10.
    • (2012) Pediatr Diabetes , vol.13 , Issue.8 , pp. 607-610
    • Hoffman, R.P.1    Dye, A.S.2    Bauer, J.A.3
  • 169
    • 33847363619 scopus 로고    scopus 로고
    • Clinical spectrum of chronic renal failure in the elderly: A hospital based study from eastern India
    • 17096077
    • Prakash J, Hota J, Singh S, Sharma O. Clinical spectrum of chronic renal failure in the elderly: a hospital based study from eastern India. Int Urol Nephrol. 2006;38:821-7.
    • (2006) Int Urol Nephrol , vol.38 , pp. 821-827
    • Prakash, J.1    Hota, J.2    Singh, S.3    Sharma, O.4
  • 171
    • 36249026988 scopus 로고    scopus 로고
    • Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats
    • 17963344 1:CAS:528:DC%2BD2sXhsVantrzO
    • Lee EY, Lee MY, Hong SW, Chung CH, Hong SY. Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats. Yonsei Med J. 2007;48(5):847-55.
    • (2007) Yonsei Med J , vol.48 , Issue.5 , pp. 847-855
    • Lee, E.Y.1    Lee, M.Y.2    Hong, S.W.3    Chung, C.H.4    Hong, S.Y.5
  • 172
    • 0035434119 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy
    • 11473058 1:CAS:528:DC%2BD3MXlslKms78%3D
    • Kowluru RA, Tang J, Kern TS. Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy. Diabetes. 2001;50:1938-42.
    • (2001) Diabetes , vol.50 , pp. 1938-1942
    • Kowluru, R.A.1    Tang, J.2    Kern, T.S.3
  • 173
    • 19944432813 scopus 로고    scopus 로고
    • Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: Improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking
    • Mustata GT, Rosca M, Biemel KM, Reihl O, Smith MA, Viswanathan A. Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking. Diabetes. 2005;4:517-26.
    • (2005) Diabetes , vol.4 , pp. 517-526
    • Mustata, G.T.1    Rosca, M.2    Biemel, K.M.3    Reihl, O.4    Smith, M.A.5    Viswanathan, A.6
  • 175
    • 0028791236 scopus 로고
    • Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats
    • 8582537 1:CAS:528:DyaK28XitlOiuw%3D%3D
    • Cotter MA, Love A, Watt MJ, Cameron NE, Dines KC. Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats. Diabetologia. 1995;38(11):1285-94.
    • (1995) Diabetologia , vol.38 , Issue.11 , pp. 1285-1294
    • Cotter, M.A.1    Love, A.2    Watt, M.J.3    Cameron, N.E.4    Dines, K.C.5
  • 176
    • 4444295693 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy
    • 15333481 1:CAS:528:DC%2BD2cXnvFKrtr4%3D
    • Ziegler D, Sohr CG, Nourooz-Zadeh J. Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy. Diabetes Care. 2004;27(9):2178-83.
    • (2004) Diabetes Care , vol.27 , Issue.9 , pp. 2178-2183
    • Ziegler, D.1    Sohr, C.G.2    Nourooz-Zadeh, J.3
  • 177
    • 77649265463 scopus 로고    scopus 로고
    • Reactive oxygen species, reactive nitrogen species and antioxidants in etiopathogenesis of diabetes mellitus type-2
    • 23105858 1:CAS:528:DC%2BC3cXmt1ehsg%3D%3D
    • Singh PP, Mahadi F, Roy A, Sharma P. Reactive oxygen species, reactive nitrogen species and antioxidants in etiopathogenesis of diabetes mellitus type-2. Indian J Clin Biochem. 2009;24(4):324-42.
    • (2009) Indian J Clin Biochem , vol.24 , Issue.4 , pp. 324-342
    • Singh, P.P.1    Mahadi, F.2    Roy, A.3    Sharma, P.4
  • 178
    • 0018101488 scopus 로고
    • Ascorbic acid, neutrophil function, and the immune response
    • 1:CAS:528:DyaE1cXkvV2it7Y%3D
    • Leibovitz B, Siegel BV. Ascorbic acid, neutrophil function, and the immune response. Int J Vit Nutr Res. 1978;48(2):159-64.
    • (1978) Int J Vit Nutr Res , vol.48 , Issue.2 , pp. 159-164
    • Leibovitz, B.1    Siegel, B.V.2
  • 179
    • 0025290055 scopus 로고
    • The effect of zinc and vitamin C supplementation on the immune status of patients with Crohn's disease
    • 16837345 1:STN:280:DC%2BD28vhsFKjtw%3D%3D
    • Animashaun A, Kelleher J, Heatley RV, Trejdosiewicz LK, Losowsky MS. The effect of zinc and vitamin C supplementation on the immune status of patients with Crohn's disease. Clin Nutr. 1990;9(3):137-46.
    • (1990) Clin Nutr , vol.9 , Issue.3 , pp. 137-146
    • Animashaun, A.1    Kelleher, J.2    Heatley, R.V.3    Trejdosiewicz, L.K.4    Losowsky, M.S.5
  • 180
    • 35248887619 scopus 로고    scopus 로고
    • Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses
    • 17922955 1:CAS:528:DC%2BD2sXhtlGmtr%2FP
    • Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr. 2007;98(1):S29-35.
    • (2007) Br J Nutr , vol.98 , Issue.1
    • Maggini, S.1    Wintergerst, E.S.2    Beveridge, S.3    Hornig, D.H.4
  • 181
    • 0020375764 scopus 로고
    • Enhancement of antibody production and protection against systemic anaphylaxis by large doses of vitamin C
    • 7163630 1:CAS:528:DyaL3sXjtlGgsQ%3D%3D
    • Feigen GA, Smith BH, Dix CE, Flynn CJ, Peterson NS, Rosenberg LT, et al. Enhancement of antibody production and protection against systemic anaphylaxis by large doses of vitamin C. Res Commun Chem Pathol Pharmacol. 1982;38(2):313-33.
    • (1982) Res Commun Chem Pathol Pharmacol , vol.38 , Issue.2 , pp. 313-333
    • Feigen, G.A.1    Smith, B.H.2    Dix, C.E.3    Flynn, C.J.4    Peterson, N.S.5    Rosenberg, L.T.6
  • 182
    • 0025880862 scopus 로고
    • Complement component C1q activity and ascorbic acid nutriture in guinea pigs
    • 1962575 1:CAS:528:DyaK38Xot1Kitw%3D%3D
    • Haskell BE, Johnston CS. Complement component C1q activity and ascorbic acid nutriture in guinea pigs. Am J Clin Nutr. 1991;54(6):1228S-30S.
    • (1991) Am J Clin Nutr , vol.54 , Issue.6
    • Haskell, B.E.1    Johnston, C.S.2
  • 183
    • 34548832512 scopus 로고    scopus 로고
    • Contribution of selected vitamins and trace elements to immune function
    • 17726308 1:CAS:528:DC%2BD2sXhtVGrsrjJ
    • Wintergerst ES, Maggini S, Hornig DH. Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab. 2007;51(4):301-23.
    • (2007) Ann Nutr Metab , vol.51 , Issue.4 , pp. 301-323
    • Wintergerst, E.S.1    Maggini, S.2    Hornig, D.H.3
  • 184
    • 78649956823 scopus 로고    scopus 로고
    • Vitamin C-treated murine bone marrow-derived dendritic cells preferentially drive naïve T cells into Th1 cells by increased IL-12 secretions
    • 21074755 1:CAS:528:DC%2BC3cXhsFGgs7bE
    • Jeong YJ, Hong SW, Kim JH, Jin DH, Kang JS, Lee WJ, et al. Vitamin C-treated murine bone marrow-derived dendritic cells preferentially drive naïve T cells into Th1 cells by increased IL-12 secretions. Cell Immunol. 2011;266(2):192-9.
    • (2011) Cell Immunol , vol.266 , Issue.2 , pp. 192-199
    • Jeong, Y.J.1    Hong, S.W.2    Kim, J.H.3    Jin, D.H.4    Kang, J.S.5    Lee, W.J.6
  • 185
    • 84868580614 scopus 로고    scopus 로고
    • Vitamin C and its physiological role with respect to the components of the immune system
    • 23121060
    • Holmannová D, Koláčková M, Krejsek J. Vitamin C and its physiological role with respect to the components of the immune system. Vnitr Lek. 2012;58(10):743-9.
    • (2012) Vnitr Lek , vol.58 , Issue.10 , pp. 743-749
    • Holmannová, D.1    Koláčková, M.2    Krejsek, J.3
  • 186
    • 84865966698 scopus 로고    scopus 로고
    • Effect of high-dose intravenous vitamin C on inflammation in cancer patients
    • 22963460 1:CAS:528:DC%2BC38XhvVSiu7fI
    • Mikirova N, Casciari J, Rogers A, Taylor P. Effect of high-dose intravenous vitamin C on inflammation in cancer patients. J Transl Med. 2012;10:189.
    • (2012) J Transl Med , vol.10 , pp. 189
    • Mikirova, N.1    Casciari, J.2    Rogers, A.3    Taylor, P.4
  • 187
    • 84864375715 scopus 로고    scopus 로고
    • Diagnostic and prognostic significance of prostate specific antigen and serum interleukin 18 and 10 in patients with locally advanced carcinoma prostate: A prospective comparative study
    • Dwivedi S, Goel A, Mandhani A, Natu SM, Khattri S, Pant KK. Diagnostic and prognostic significance of prostate specific antigen and serum interleukin 18 and 10 in patients with locally advanced carcinoma prostate: a prospective comparative study. Asian Pacific J Cancer Prev. 2011;12:1639-44.
    • (2011) Asian Pacific J Cancer Prev , vol.12 , pp. 1639-1644
    • Dwivedi, S.1    Goel, A.2    Mandhani, A.3    Natu, S.M.4    Khattri, S.5    Pant, K.K.6
  • 188
    • 84886364616 scopus 로고    scopus 로고
    • Non-invasive biomarker in prostate cancer - A novel approach
    • Dwivedi S, Shukla KK, Gupta G, Sharma P. Non-invasive biomarker in prostate cancer - a novel approach. Ind J Clin Biochem. 2013;28(2):107-9.
    • (2013) Ind J Clin Biochem , vol.28 , Issue.2 , pp. 107-109
    • Dwivedi, S.1    Shukla, K.K.2    Gupta, G.3    Sharma, P.4
  • 189
    • 0029646919 scopus 로고
    • Interrelation of vitamin C, infection, haemostatic factors and cardiovascular disease
    • 7787643 1:STN:280:DyaK2MzgslegsA%3D%3D
    • Khaw KT, Woodhouse P. Interrelation of vitamin C, infection, haemostatic factors and cardiovascular disease. BMJ. 1995;310:1559-63.
    • (1995) BMJ , vol.310 , pp. 1559-1563
    • Khaw, K.T.1    Woodhouse, P.2
  • 190
    • 0030432482 scopus 로고    scopus 로고
    • Vitamin C and cardiovascular disease - A systematic review
    • Ness AR, Powles JW, Khaw KT. Vitamin C and cardiovascular disease - a systematic review. J Cardiovasc Risk. 1997;3:513-21.
    • (1997) J Cardiovasc Risk , vol.3 , pp. 513-521
    • Ness, A.R.1    Powles, J.W.2    Khaw, K.T.3
  • 191
    • 0030761812 scopus 로고    scopus 로고
    • Epidemiology of coagulation factors, inhibitors and activation markers: The third Glasgow MONICA study (2). Relationships to cardiovascular risk factors and prevalent cardiovascular disease
    • 9217177 1:STN:280:DyaK2szmtVWnuw%3D%3D
    • Woodward M, Lowe GDO, Rumley A, Tunstall-Pedoe H, Philippou H, Lane DA. Epidemiology of coagulation factors, inhibitors and activation markers: the third Glasgow MONICA study (2). Relationships to cardiovascular risk factors and prevalent cardiovascular disease. Br J Haematol. 1997;97:785-97.
    • (1997) Br J Haematol , vol.97 , pp. 785-797
    • Woodward, M.1    Lowe, G.D.O.2    Rumley, A.3    Tunstall-Pedoe, H.4    Philippou, H.5    Lane, D.A.6
  • 192
    • 0032912784 scopus 로고    scopus 로고
    • Association of blood rheology and interleukin-6 with cardiovascular risk factors and prevalent cardiovascular disease
    • 10050704 1:STN:280:DyaK1M7lsl2qsw%3D%3D
    • Woodward M, Rumley A, Tunstall-Pedoe H, Lowe GDO. Association of blood rheology and interleukin-6 with cardiovascular risk factors and prevalent cardiovascular disease. Br J Haematol. 1999;104:246-57.
    • (1999) Br J Haematol , vol.104 , pp. 246-257
    • Woodward, M.1    Rumley, A.2    Tunstall-Pedoe, H.3    Lowe, G.D.O.4
  • 193
    • 0038345246 scopus 로고    scopus 로고
    • C-reactive protein: Associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease
    • 12823355 1:CAS:528:DC%2BD3sXmtVGntbk%3D
    • Woodward M, Rumley A, Lowe GDO, Tunstall-Pedoe H. C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease. Br J Haematol. 2003;122:135-41.
    • (2003) Br J Haematol , vol.122 , pp. 135-141
    • Woodward, M.1    Rumley, A.2    Lowe, G.D.O.3    Tunstall-Pedoe, H.4
  • 194
    • 1842582865 scopus 로고    scopus 로고
    • Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in hispanic and non-hispanic white elders
    • 15051846 1:CAS:528:DC%2BD2cXjtFWmtbs%3D
    • Gao X, Bermudez OI, Tucker KL. Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in hispanic and non-hispanic white elders. J Nutr. 2004;134:913-8.
    • (2004) J Nutr , vol.134 , pp. 913-918
    • Gao, X.1    Bermudez, O.I.2    Tucker, K.L.3
  • 195
    • 0141627702 scopus 로고    scopus 로고
    • C-reactive protein concentration and concentrations of blood vitamins, carotenoids, and selenium among United States adults
    • 12947436 1:CAS:528:DC%2BD3sXmslemtbY%3D
    • Ford ES, Liu S, Mannino DM, Giles WH, Smith SJ. C-reactive protein concentration and concentrations of blood vitamins, carotenoids, and selenium among United States adults. Eur J Clin Nutr. 2003;57:1157-63.
    • (2003) Eur J Clin Nutr , vol.57 , pp. 1157-1163
    • Ford, E.S.1    Liu, S.2    Mannino, D.M.3    Giles, W.H.4    Smith, S.J.5
  • 196
    • 28344452909 scopus 로고    scopus 로고
    • Circulating inflammatory markers and risks of cardiovascular and non-cardiovascular disease
    • 16102027 1:STN:280:DC%2BD2Mvjs1emsg%3D%3D
    • Lowe GDO. Circulating inflammatory markers and risks of cardiovascular and non-cardiovascular disease. J Thromb Haemost. 2005;3:1618-27.
    • (2005) J Thromb Haemost , vol.3 , pp. 1618-1627
    • Lowe, G.D.O.1
  • 197
    • 33644697589 scopus 로고    scopus 로고
    • Immune-enhancing role of vitamin C and zinc and effect on clinical conditions
    • 16373990 1:CAS:528:DC%2BD28XhvVyquro%3D
    • Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94.
    • (2006) Ann Nutr Metab , vol.50 , Issue.2 , pp. 85-94
    • Wintergerst, E.S.1    Maggini, S.2    Hornig, D.H.3
  • 198
    • 0028798434 scopus 로고
    • Mechanisms in the toxicity of metal ions
    • 7744317 1:CAS:528:DyaK2MXjsFOrsLg%3D
    • Stohs SJ, Bagchi D. Mechanisms in the toxicity of metal ions. Free Radic Biol Med. 1995;18(2):321-36.
    • (1995) Free Radic Biol Med , vol.18 , Issue.2 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 199
    • 79851516223 scopus 로고    scopus 로고
    • Influence of vitamin C supplementation on lead-induced histopathological alterations in male rats
    • 20056397 1:CAS:528:DC%2BC3MXit1WrsL4%3D
    • Shaban El-Neweshy M, Said El-Sayed Y. Influence of vitamin C supplementation on lead-induced histopathological alterations in male rats. Exp Toxicol Pathol. 2011;63(3):221-7.
    • (2011) Exp Toxicol Pathol , vol.63 , Issue.3 , pp. 221-227
    • Shaban El-Neweshy, M.1    Said El-Sayed, Y.2
  • 200
    • 78751488946 scopus 로고    scopus 로고
    • Effect of l-ascorbic acid and/or tocopherol supplementation on electrophysiological parameters of the colon of rats chronically exposed to lead
    • 21169903 1:CAS:528:DC%2BC3MXitlersr8%3D
    • Kosik-Bogacka DI, Baranowska-Bosiacka I, Marchlewicz M, Kolasa A, Jakubowska K, Olszewska M, et al. Effect of l-ascorbic acid and/or tocopherol supplementation on electrophysiological parameters of the colon of rats chronically exposed to lead. Med Sci Monit. 2011;17(1):BR16-26.
    • (2011) Med Sci Monit , vol.17 , Issue.1
    • Kosik-Bogacka, D.I.1    Baranowska-Bosiacka, I.2    Marchlewicz, M.3    Kolasa, A.4    Jakubowska, K.5    Olszewska, M.6
  • 201
    • 0034096537 scopus 로고    scopus 로고
    • Does vitamin C intake protect against lead toxicity?
    • 10812921 1:STN:280:DC%2BD3c3nt1yjsw%3D%3D
    • Houston DK, Johnson MA. Does vitamin C intake protect against lead toxicity? Nutr Rev. 2000;58(3):73-5.
    • (2000) Nutr Rev , vol.58 , Issue.3 , pp. 73-75
    • Houston, D.K.1    Johnson, M.A.2
  • 203
    • 84876730340 scopus 로고    scopus 로고
    • Toxic effects of perinatal arsenic exposure on the brain of developing rats and the beneficial role of natural antioxidants
    • 23619517 1:CAS:528:DC%2BC3sXnsFWjsL8%3D
    • Herrera A, Pineda J, Antonio MT. Toxic effects of perinatal arsenic exposure on the brain of developing rats and the beneficial role of natural antioxidants. Environ Toxicol Pharmacol. 2013;36(1):73-9.
    • (2013) Environ Toxicol Pharmacol , vol.36 , Issue.1 , pp. 73-79
    • Herrera, A.1    Pineda, J.2    Antonio, M.T.3
  • 204
    • 84878350666 scopus 로고    scopus 로고
    • Hematological effects of arsenic in rats after subchronical exposure during pregnancy and lactation: The protective role of antioxidants
    • 22727912 1:CAS:528:DC%2BC38XptFahurY%3D
    • Antonio Garcia MT, Herrera Dueñas A, Pineda Pampliega J. Hematological effects of arsenic in rats after subchronical exposure during pregnancy and lactation: the protective role of antioxidants. Exp Toxicol Pathol. 2013;65(5):609-14.
    • (2013) Exp Toxicol Pathol , vol.65 , Issue.5 , pp. 609-614
    • Antonio Garcia, M.T.1    Herrera Dueñas, A.2    Pineda Pampliega, J.3
  • 205
    • 77953010292 scopus 로고    scopus 로고
    • Ascorbic acid improves mitochondrial function in liver of arsenic-treated rat
    • 20356860
    • Singh S, Rana SV. Ascorbic acid improves mitochondrial function in liver of arsenic-treated rat. Toxicol Ind Health. 2010;26(5):265-72.
    • (2010) Toxicol Ind Health , vol.26 , Issue.5 , pp. 265-272
    • Singh, S.1    Rana, S.V.2
  • 206
    • 84895071818 scopus 로고    scopus 로고
    • Arsenic-induced hepatic toxicity and its attenuation by fruit extract of Emblica officinalis (amla) in mice
    • doi: 10.1007/s12291-013-0353-9
    • Singh MK, Dwivedi S, Yadav SS, Sharma P, Khattri S. Arsenic-induced hepatic toxicity and its attenuation by fruit extract of Emblica officinalis (amla) in mice. Ind J Clin Biochem. 2013. doi: 10.1007/s12291-013-0353-9.
    • (2013) Ind J Clin Biochem
    • Singh, M.K.1    Dwivedi, S.2    Yadav, S.S.3    Sharma, P.4    Khattri, S.5
  • 207
    • 79955066759 scopus 로고    scopus 로고
    • The protective role of vitamin C against cerebral and pulmonary damage induced by cadmium chloride in male adult albino rat
    • 1:CAS:528:DC%2BC3MXktl2ktbg%3D
    • El-Sokkary GH, Awadalla EA. The protective role of vitamin C against cerebral and pulmonary damage induced by cadmium chloride in male adult albino rat. Open Neuroendocrinol J. 2011;4:1-8.
    • (2011) Open Neuroendocrinol J , vol.4 , pp. 1-8
    • El-Sokkary, G.H.1    Awadalla, E.A.2
  • 208
    • 84883141597 scopus 로고    scopus 로고
    • Protective effects of vitamin C on haematological parameters in intoxicated Wistar rats with cadmium, mercury and combined cadmium and mercury
    • Hounkpatin ASY, Johnson RC, Guédénon P, Domingo E, Alimba CG, Boko M. Protective effects of vitamin C on haematological parameters in intoxicated Wistar rats with cadmium, mercury and combined cadmium and mercury. Int Res J Biol Sci. 2012;1(8):76-81.
    • (2012) Int Res J Biol Sci , vol.1 , Issue.8 , pp. 76-81
    • Hounkpatin, A.S.Y.1    Johnson, R.C.2    Guédénon, P.3    Domingo, E.4    Alimba, C.G.5    Boko, M.6
  • 209
    • 72549088130 scopus 로고    scopus 로고
    • Vitamin C against concomitant exposure to heavy metal and radiation: A study on variations in hepatic cellular counts
    • 1:CAS:528:DC%2BD2MXpvVWrtr8%3D
    • Gajawat S, Sancheti G, Goyal PK. Vitamin C against concomitant exposure to heavy metal and radiation: a study on variations in hepatic cellular counts. Asian J Exp Sci. 2005;19(2):53-8.
    • (2005) Asian J Exp Sci , vol.19 , Issue.2 , pp. 53-58
    • Gajawat, S.1    Sancheti, G.2    Goyal, P.K.3
  • 210
    • 84886372713 scopus 로고
    • C-vitamin und schizophrenic
    • Lucksch F. C-vitamin und schizophrenic. Wien Klin Wochenschr. 1940;53:1009-11.
    • (1940) Wien Klin Wochenschr , vol.53 , pp. 1009-1011
    • Lucksch, F.1
  • 212
    • 0034499731 scopus 로고    scopus 로고
    • Erythrocyte superoxide dismutase and glutathion peroxidase activities and malondialdehyde and reduced glutathione levels in schizophrenic patients
    • 11205693 1:CAS:528:DC%2BD3MXhsFWhurk%3D
    • Altuntas I, Aksoy H, Coskun I, Caykoylu A, Akcay F. Erythrocyte superoxide dismutase and glutathion peroxidase activities and malondialdehyde and reduced glutathione levels in schizophrenic patients. Clin Chem Lab Med. 2000;38:1277-81.
    • (2000) Clin Chem Lab Med , vol.38 , pp. 1277-1281
    • Altuntas, I.1    Aksoy, H.2    Coskun, I.3    Caykoylu, A.4    Akcay, F.5
  • 213
    • 0028567709 scopus 로고
    • Erythrocyte superoxide dismutase determination in positive moments of psychosis
    • 7878602 1:CAS:528:DyaK2MXmvVWgu7Y%3D
    • Vaiva G, Thomas P, Leroux JM. Erythrocyte superoxide dismutase determination in positive moments of psychosis. Therapie. 1994;49:343-8.
    • (1994) Therapie , vol.49 , pp. 343-348
    • Vaiva, G.1    Thomas, P.2    Leroux, J.M.3
  • 214
    • 0025833277 scopus 로고
    • Enzymes of the antioxidant system in chronic schizophrenic patients
    • 1912133 1:STN:280:DyaK38%2Fgt1Gmug%3D%3D
    • Reddy R, Mahadik SP, Mukherjee M, Murty JN. Enzymes of the antioxidant system in chronic schizophrenic patients. Biol Psychiatry. 1991;30:409-12.
    • (1991) Biol Psychiatry , vol.30 , pp. 409-412
    • Reddy, R.1    Mahadik, S.P.2    Mukherjee, M.3    Murty, J.N.4
  • 215
    • 0036096195 scopus 로고    scopus 로고
    • Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder
    • Kuloghi M, Ustundag B, Atmaca M, Canatan H, Tezean AE, Cinkiline N. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct. 2002;20:171-5.
    • (2002) Cell Biochem Funct , vol.20 , pp. 171-175
    • Kuloghi, M.1    Ustundag, B.2    Atmaca, M.3    Canatan, H.4    Tezean, A.E.5    Cinkiline, N.6
  • 216
    • 0001939357 scopus 로고
    • Elevated levels of lipid peroxidation products in plasma from drug-naive patients at onset of psychosis
    • Mahadik SP, Mukherjee S, Correnti I, Sheffer R. Elevated levels of lipid peroxidation products in plasma from drug-naive patients at onset of psychosis. Schizophr Res. 1995;15:66-70.
    • (1995) Schizophr Res , vol.15 , pp. 66-70
    • Mahadik, S.P.1    Mukherjee, S.2    Correnti, I.3    Sheffer, R.4
  • 217
    • 0037223550 scopus 로고    scopus 로고
    • Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients
    • 12513945 1:CAS:528:DC%2BD38XpvVajtLg%3D
    • Arvindakshan M, Sitasawad S, Debsikdar V, Ghate M, Evans D, Horrobin DF, et al. Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients. Biol Psychiatry. 2003;53:56-64.
    • (2003) Biol Psychiatry , vol.53 , pp. 56-64
    • Arvindakshan, M.1    Sitasawad, S.2    Debsikdar, V.3    Ghate, M.4    Evans, D.5    Horrobin, D.F.6
  • 219
    • 0020644952 scopus 로고
    • Superoxide radical: An endogenous toxicant
    • 6307121 1:CAS:528:DyaL3sXktFOmsbw%3D
    • Fridovich I. Superoxide radical: an endogenous toxicant. Annu Rev Pharmacol Toxicol. 1983;23:239-57.
    • (1983) Annu Rev Pharmacol Toxicol , vol.23 , pp. 239-257
    • Fridovich, I.1
  • 220
    • 63249086149 scopus 로고    scopus 로고
    • Evaluation of antioxidant deficit in schizophrenia
    • 19771301
    • Dadheech G, Mishra S, Gautam S, Sharma P. Evaluation of antioxidant deficit in schizophrenia. Indian J Psychiatry. 2008;50(1):16-20.
    • (2008) Indian J Psychiatry , vol.50 , Issue.1 , pp. 16-20
    • Dadheech, G.1    Mishra, S.2    Gautam, S.3    Sharma, P.4
  • 221
    • 0018154839 scopus 로고
    • Protective role of brain ascorbic acid content against lipid peroxidation
    • 700025 1:CAS:528:DyaE1cXls1Sks7g%3D
    • Seregi A, Schaefer A, Komlos M. Protective role of brain ascorbic acid content against lipid peroxidation. Experientia. 1978;34:1056-7.
    • (1978) Experientia , vol.34 , pp. 1056-1057
    • Seregi, A.1    Schaefer, A.2    Komlos, M.3
  • 222
    • 0023074935 scopus 로고
    • Ascorbic acid distribution pattern in human brain
    • 1987
    • Oke AI, May L, Adams RN (1987). Ascorbic acid distribution pattern in human brain. Ann NY Acad Sci. 1987;498:1-12.
    • (1987) Ann NY Acad Sci. , vol.498 , pp. 1-12
    • Oke, A.I.1    May, L.2    Adams, R.N.3
  • 223
    • 0037783989 scopus 로고    scopus 로고
    • Supplementation with a combination of omega 3 fatty acids and antioxidants (vitamin e and C) improves the outcome of schizophrenia
    • 12837515
    • Arvindakshan M, Ghate M, Ranjekar PK, Evans DR, Mahadik SP. Supplementation with a combination of omega 3 fatty acids and antioxidants (vitamin E and C) improves the outcome of schizophrenia. Schizophr Res. 2003;62:195-204.
    • (2003) Schizophr Res , vol.62 , pp. 195-204
    • Arvindakshan, M.1    Ghate, M.2    Ranjekar, P.K.3    Evans, D.R.4    Mahadik, S.P.5
  • 224
    • 33751057741 scopus 로고    scopus 로고
    • Oxidative stress - Tocopherol, ascorbic acid and reduced glutathione status in schizophrenics
    • 23105610 1:CAS:528:DC%2BD28Xht12hsb3E
    • Dadheech G, Mishra S, Gautam S, Sharma P. Oxidative stress - tocopherol, ascorbic acid and reduced glutathione status in schizophrenics. Indian J Clin Biochem. 2006;21(2):34-8.
    • (2006) Indian J Clin Biochem , vol.21 , Issue.2 , pp. 34-38
    • Dadheech, G.1    Mishra, S.2    Gautam, S.3    Sharma, P.4
  • 225
    • 26844535408 scopus 로고    scopus 로고
    • Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia
    • 16133138 1:CAS:528:DC%2BD2MXhtFahtbzK
    • Dakhale GN, Khanzode SD, Khanzode SS, Saoji A. Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia. Psychopharmacology. 2005;182:494-8.
    • (2005) Psychopharmacology , vol.182 , pp. 494-498
    • Dakhale, G.N.1    Khanzode, S.D.2    Khanzode, S.S.3    Saoji, A.4
  • 227
    • 84860161652 scopus 로고    scopus 로고
    • A critical review of vitamin C for the prevention of age-related cognitive decline and Alzheimer's disease
    • 22366772 1:CAS:528:DC%2BC38XlslGqt70%3D
    • Harrison FE. A critical review of vitamin C for the prevention of age-related cognitive decline and Alzheimer's disease. J Alzheimers Dis. 2012;29(4):711-26.
    • (2012) J Alzheimers Dis , vol.29 , Issue.4 , pp. 711-726
    • Harrison, F.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.