C-reactive protein: Associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease

British Journal of Haematology

Volumn 122, Issue 1, 2003, Pages 135-141

  Woodward, Mark ^a,d   Rumley, Ann ^b   Lowe, Gordon D O ^b   Tunstall Pedoe, Hugh ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b GLASGOW ROYAL INFIRMARY   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d Institute for Health Research   (Australia)

Author keywords

C reactive protein; Cardiovascular disease; Fibrinogen; Inflammation; Thrombosis

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; C REACTIVE PROTEIN; FIBRINOGEN; INTERLEUKIN 6; PROTEIN C; PROTEIN S;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DIAGNOSTIC VALUE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK FACTOR; THROMBOSIS;

ADULT; AGED; AGING; ALCOHOL DRINKING; BIOLOGICAL MARKERS; BLOOD COAGULATION; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; FEMALE; HEMORHEOLOGY; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; RISK FACTORS; SEX FACTORS; SMOKING; SOCIAL CLASS; STATISTICS;

EID: 0038345246     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04387.x     Document Type: Article

References (28)

1. Crombie, I.K., Smith, W.C.S., Irving, J.M. & Tunstall-Pedoe, H.D. (1989) Experience with general practitioner lists as a sampling frame for a survey of cardiovascular risk factors. Statistician, 38, 25-31.
2. Cushman, M., Meilahn, E.N., Psaty, B.B., Kuller, L.H., Dobs, A.S. & Tracy, R.P. (1999) Hormone replacement therapy, inflammation and hemostasis in elderly women. Arterioscleorosis, Thrombosis and Vascular Biology, 19, 893-899.
3. Danesh, J., Muir, J., Wang, Y.K., Ward, M., Gallimore, J.R. & Pepys, M.B. (1999) Risk factors for coronary heart disease and acute-phase proteins. A population-based study. European Heart Journal, 20, 954-959.
4. Danesh, J., Whincup, P., Walker, M., Lennon, L., Thomson, A., Appleby, P., Gallimore, J.R. & Pepys, M.B. (2000a) Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. British Medical Journal, 321, 199-204.
5. Danesh, J., Collins, R., Peto, R. & Lowe, G.D.O. (2000b) Haematocrit, viscosity, erthryocyte sedimentation rate: meta-analyses of prospective studies of coronary heart disease. European Heart Journal, 21, 515-520.
6. Ford, E.S. & Giles, W.H. (2000) Serum C-reactive protein and self-reported stroke. Arteriosclerosis, Thrombosis and Vascular Biology, 20, 1052-1056.
7. Fröhlich, M., Doring, A., Imhof, A., Hutchinson, W.L., Pepys, M.B. & Koenig, K. (1999) Oral contraceptive use is associated with a systemic acute phase response. Fibrinolysis and Proteolysis, 13, 226-238.
8. Gussekloo, J., Schap, M.C.L., Frölich, M., Blauw, G.J. & Westemdorp, R.G.J. (2000) C-reactive protein is a strong but non-specific risk factor of fatal stroke in elderly persons. Arteriosclerosis, Thrombosis and Vascular Biology, 20, 1047-1051.
9. Hak, A.E., Stehouwer, C.D.A., Bots, M.L., Polderman, W.H., Schalkwijk, C.G., Westendorp, I.C.D., Hofman, A. & Witteman, J.C.M. (1999) Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women. Arteriosclerosis, Thrombosis and Vascular Biology, 19, 1986-1991.
10. Hutchison, W.L., Koenig, W., Frolich, M., Sund, M., Lowe, G.D.O. & Pepys, M.B. (2000) Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clinical Chemistry, 46, 934-938.
11. Imhof, A., Fröhlich, M., Loewel, H., Helbecque, N., Woodward, M., Amouyel, P., Lowe, G.D.O. & Koenig, W. (2003) Distributions of C-Reactive Protein measured by high-sensitivity assays in apparently healthy men and women from different populations in Europe. Clinical Chemistry, 49, 669-672.
12. Lagrand, W.K., Visser, C.A., Hermens, W.T., Niessen, H.W.M., Verheugt, F.W.A., Wolbiak, G.J. & Hack, C.E. (1999) C-reactive protein as a cardiovascular risk factor. More than an epiphenomenon? Circulation, 100, 96-102.
13. Lowe, G.D.O. (2001) Ancrod in treatment of acute ischaemic stroke. Proceedings of the Royal College of Physicians of Edinburgh, 31, 20-24.
14. Lowe, G.D.O., Rumley, A., Woodward, M., Morrison, C.E., Philippou, H., Lane, D.A. & Tunstall-Pedoe, H. (1997) Epidemiology of coagulation factors, inhibitors and activation markers: the Third Glasgow MONICA Survey I. Illustrative reference ranges by age, sex and hormone use. British Journal of Haematology, 97, 775-784.
15. 506Q mutation in a random sample: associations with cardiovascular risk factors and coagulation variables. Thrombosis and Haemostasis, 81, 918-924.
16. Lowe, G.D.O., Rumley, A., Norrie, J., Ford, I., Shepherd, J., Cobbe, S., Macfarlane, P. & Packard C. on behalf of the West of Scotland Coronary Prevention Group (2000) Blood rheology, cardiovascular risk factors, and cardiovascular disease: the West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis, 84, 553-558.
17. Lowe, G.D.O., Yarnell, J.W.G., Rumley, A., Bainton, D. & Sweetnam, P.M. (2001) C-reactive protein, fibrin D-dimer, and incident ischemic heart disease in the Speedwell Study. Are inflammation and fibrin turnover linked in pathogenesis? Arteriosclerosis, Thrombosis and Vascular Biology, 21, 603-610.
18. Mendall, M.A., Strachan, D.P., Butland, B.K., Ballam, L., Morris, J., Sweetnam, P.M. & Elwood, P.C. (2000) C-reactive protein: relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men. European Heart Journal, 21, 1584-1590.
19. Office of Population Censuses and Surveys (1990) Classification of Occupations. HMSO, London.
20. Ridker, P.M., Cushman, M., Stampfer, M.J., Tracy, R.P. & Hennekens, C.H. (1998) Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation, 97, 425-428.
21. Ridker, P.M., Hennekens, C.H., Rifai, N., Buring, J.E. & Manson, J.E. (1999) Hormone replacement therapy and increased plasma concentration of C-reactive protein. Circulation, 100, 713-716.
22. Smith, W.C.S., Tunstall-Pedoe, H., Crombie, I.K. & Tavendale, R. (1989) Concomitants of excess coronary deaths: major risk factor and life-style findings from 10,359 men and women in the Scottish heart health study. Scottish Medical Journal, 34, 550-555.
23. Vuilleumier, J.P. & Keck, E. (1989) Fluorometric assay of vitamin C in biological samples using a centrifugal analyser with fluorescence attachment. Journal of Micronutrient Analysis, 5, 25-34.
24. Woodward, M., Tunstall-Pedoe, H., Smith, W.C.S. & Tavendale, R. (1991) Smoking characteristics and inhalation biochemistry in the Scottish population. Journal of Clinical Epidemiology, 44, 1405-1410.
25. Woodward, M., Lowe, G.D.O., Rumley, A., Tunstall-Pedoe, H., Philippou, H., Lane, D.A. & Morrison, C.E. (1997) Epidemiology of coagulation factors, inhibitors and activation markers: the Third Glasgow MONICA Survey. II. Relationships to cardiovascular risk factors and prevalent cardiovascular disease. British Journal of Haematology, 97, 785-797.
26. Woodward, M., Rumley, A., Tunstall-Pedoe, H. & Lowe, G.D.O. (1999) Associations of blood rheology and interleukin 6 with cardiovascular risk factors and prevalent cardiovascular disease. British Journal of Haematology, 104, 246-257.
27. World Health Organisation Principal Investigators (1988) The World Health Organisation MONICA. Project (monitoring trends and determinants in cardiovascular disease): a major international collaboration. Journal of Clinical Epidemiology, 41, 105-113.
28. Yudkin, J.S., Stehouwer, C.D.A., Emeis, J.J. & Coppack, S.W. (1999) C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction. Arteriosclerosis, Thrombosis and Vascular Biology, 19, 972-978.