-
1
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in doublestranded RNA-induced innate antiviral responses
-
Yoneyama M, et al. (2004) The RNA helicase RIG-I has an essential function in doublestranded RNA-induced innate antiviral responses. Nat Immunol 5(7):730-737.
-
(2004)
Nat Immunol
, vol.5
, Issue.7
, pp. 730-737
-
-
Yoneyama, M.1
-
2
-
-
33744494279
-
Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila
-
Galiana-Arnoux D, Dostert C, Schneemann A, Hoffmann JA, Imler J-L (2006) Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila. Nat Immunol 7(6):590-597.
-
(2006)
Nat Immunol
, vol.7
, Issue.6
, pp. 590-597
-
-
Galiana-Arnoux, D.1
Dostert, C.2
Schneemann, A.3
Hoffmann, J.A.4
Imler, J.-L.5
-
3
-
-
56349115840
-
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila
-
Deddouche S, et al. (2008) The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Nat Immunol 9(12):1425-1432.
-
(2008)
Nat Immunol
, vol.9
, Issue.12
, pp. 1425-1432
-
-
Deddouche, S.1
-
4
-
-
77956170809
-
RNA-based antiviral immunity
-
Ding S-W (2010) RNA-based antiviral immunity. Nat Rev Immunol 10(9):632-644.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.9
, pp. 632-644
-
-
Ding, S.-W.1
-
5
-
-
33745916446
-
Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense
-
Deleris A, et al. (2006) Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense. Science 313(5783):68-71.
-
(2006)
Science
, vol.313
, Issue.5783
, pp. 68-71
-
-
Deleris, A.1
-
6
-
-
34547587566
-
Antiviral immunity directed by small RNAs
-
Ding SW, Voinnet O (2007) Antiviral immunity directed by small RNAs. Cell 130(3): 413-426.
-
(2007)
Cell
, vol.130
, Issue.3
, pp. 413-426
-
-
Ding, S.W.1
Voinnet, O.2
-
7
-
-
84866182888
-
Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses
-
van Mierlo JT, et al. (2012) Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses. PLoS Pathog 8(8):e1002872.
-
(2012)
PLoS Pathog
, vol.8
, Issue.8
-
-
Van Mierlo, J.T.1
-
8
-
-
0033598840
-
Suppression of gene silencing: A general strategy used by diverse DNA and RNA viruses of plants
-
Voinnet O, Pinto YM, Baulcombe DC (1999) Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc Natl Acad Sci USA 96(24):14147-14152.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.24
, pp. 14147-14152
-
-
Voinnet, O.1
Pinto, Y.M.2
Baulcombe, D.C.3
-
9
-
-
33744476400
-
Is RNA interference involved in intrinsic antiviral immunity in mammals?
-
Cullen BR (2006) Is RNA interference involved in intrinsic antiviral immunity in mammals? Nat Immunol 7(6):563-567.
-
(2006)
Nat Immunol
, vol.7
, Issue.6
, pp. 563-567
-
-
Cullen, B.R.1
-
10
-
-
82955233640
-
Virus-derived siRNAs and piRNAs in immunity and pathogenesis
-
Ding S-W, Lu R (2011) Virus-derived siRNAs and piRNAs in immunity and pathogenesis. Curr Opin Virol 1(6):533-544.
-
(2011)
Curr Opin Virol
, vol.1
, Issue.6
, pp. 533-544
-
-
Ding, S.-W.1
Lu, R.2
-
11
-
-
72949096858
-
Evolution of host innate defence: Insights from Caenorhabditis elegans and primitive invertebrates
-
Irazoqui JE, Urbach JM, Ausubel FM (2010) Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat Rev Immunol 10(1): 47-58.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.1
, pp. 47-58
-
-
Irazoqui, J.E.1
Urbach, J.M.2
Ausubel, F.M.3
-
12
-
-
23944506789
-
Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
-
Lu R, et al. (2005) Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans. Nature 436(7053):1040-1043.
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 1040-1043
-
-
Lu, R.1
-
13
-
-
23944506289
-
RNA interference is an antiviral defence mechanism in Caenorhabditis elegans
-
Wilkins C, et al. (2005) RNA interference is an antiviral defence mechanism in Caenorhabditis elegans. Nature 436(7053):1044-1047.
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 1044-1047
-
-
Wilkins, C.1
-
14
-
-
29444455712
-
An antiviral role for the RNA interference machinery in Caenorhabditis elegans
-
Schott DH, Cureton DK, Whelan SP, Hunter CP (2005) An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc Natl Acad Sci USA 102(51): 18420-18424.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.51
, pp. 18420-18424
-
-
Schott, D.H.1
Cureton, D.K.2
Whelan, S.P.3
Hunter, C.P.4
-
15
-
-
61449248246
-
An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans
-
Lu R, Yigit E, Li WX, Ding SW (2009) An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans. PLoS Pathog 5(2):e1000286.
-
(2009)
PLoS Pathog
, vol.5
, Issue.2
-
-
Lu, R.1
Yigit, E.2
Li, W.X.3
Ding, S.W.4
-
16
-
-
79851477108
-
Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses
-
Félix M-A, et al. (2011) Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses. PLoS Biol 9(1):e1000586.
-
(2011)
PLoS Biol
, vol.9
, Issue.1
-
-
Félix, M.-A.1
-
17
-
-
83255184978
-
Transgenerational inheritance of an acquired small RNA-based antiviral response in C
-
Rechavi O, Minevich G, Hobert O (2011) Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans. Cell 147(6):1248-1256.
-
(2011)
Elegans. Cell
, vol.147
, Issue.6
, pp. 1248-1256
-
-
Rechavi, O.1
Minevich, G.2
Hobert, O.3
-
18
-
-
0037188904
-
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C
-
Tabara H, Yigit E, Siomi H, Mello CC (2002) The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109(7): 861-871.
-
(2002)
Elegans. Cell
, vol.109
, Issue.7
, pp. 861-871
-
-
Tabara, H.1
Yigit, E.2
Siomi, H.3
Mello, C.C.4
-
19
-
-
59649119705
-
RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans
-
Steiner FA, Okihara KL, Hoogstrate SW, Sijen T, Ketting RF (2009) RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans. Nat Struct Mol Biol 16(2):207-211.
-
(2009)
Nat Struct Mol Biol
, vol.16
, Issue.2
, pp. 207-211
-
-
Steiner, F.A.1
Okihara, K.L.2
Hoogstrate, S.W.3
Sijen, T.4
Ketting, R.F.5
-
20
-
-
0032717319
-
The rde-1 gene, RNA interference, and transposon silencing in C
-
Tabara H, et al. (1999) The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99(2):123-132.
-
(1999)
Elegans. Cell
, vol.99
, Issue.2
, pp. 123-132
-
-
Tabara, H.1
-
21
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C
-
Ketting RF, et al. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15(20):2654-2659.
-
(2001)
Elegans. Genes Dev
, vol.15
, Issue.20
, pp. 2654-2659
-
-
Ketting, R.F.1
-
22
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen T, et al. (2001) On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107(4):465-476.
-
(2001)
Cell
, vol.107
, Issue.4
, pp. 465-476
-
-
Sijen, T.1
-
23
-
-
33846527241
-
Distinct populations of primary and secondary effectors during RNAi in C
-
Pak J, Fire A (2007) Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science 315(5809):241-244.
-
(2007)
Elegans. Science
, vol.315
, Issue.5809
, pp. 241-244
-
-
Pak, J.1
Fire, A.2
-
24
-
-
33846524902
-
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class
-
Sijen T, Steiner FA, Thijssen KL, Plasterk RH (2007) Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science 315(5809):244-247.
-
(2007)
Science
, vol.315
, Issue.5809
, pp. 244-247
-
-
Sijen, T.1
Steiner, F.A.2
Thijssen, K.L.3
Plasterk, R.H.4
-
25
-
-
70349476898
-
Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C
-
Gu W, et al. (2009) Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Mol Cell 36(2):231-244.
-
(2009)
Elegans Germline. Mol Cell
, vol.36
, Issue.2
, pp. 231-244
-
-
Gu, W.1
-
26
-
-
81555204380
-
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
-
Jiang F, et al. (2011) Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature 479(7373):423-427.
-
(2011)
Nature
, vol.479
, Issue.7373
, pp. 423-427
-
-
Jiang, F.1
-
27
-
-
80054685883
-
Structural insights into RNA recognition by RIG-I
-
Luo D, et al. (2011) Structural insights into RNA recognition by RIG-I. Cell 147(2): 409-422.
-
(2011)
Cell
, vol.147
, Issue.2
, pp. 409-422
-
-
Luo, D.1
-
28
-
-
84555178934
-
Structural insights into the activation of RIG-I, a nanosensor for viral RNAs
-
Jiang Q-X, Chen ZJ (2012) Structural insights into the activation of RIG-I, a nanosensor for viral RNAs. EMBO Rep 13(1):7-8.
-
(2012)
EMBO Rep
, vol.13
, Issue.1
, pp. 7-8
-
-
Jiang, Q.-X.1
Chen, Z.J.2
-
29
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, et al. (2005) Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175(5):2851-2858.
-
(2005)
J Immunol
, vol.175
, Issue.5
, pp. 2851-2858
-
-
Yoneyama, M.1
-
30
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441(7089):101-105.
-
(2006)
Nature
, vol.441
, Issue.7089
, pp. 101-105
-
-
Kato, H.1
-
31
-
-
26844503987
-
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
-
Rothenfusser S, et al. (2005) The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J Immunol 175(8):5260-5268.
-
(2005)
J Immunol
, vol.175
, Issue.8
, pp. 5260-5268
-
-
Rothenfusser, S.1
-
32
-
-
64549126847
-
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA
-
Pippig DA, et al. (2009) The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA. Nucleic Acids Res 37(6):2014-2025.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.6
, pp. 2014-2025
-
-
Pippig, D.A.1
-
33
-
-
76549109497
-
LGP2 is a positive regulator of RIG-I and MDA5-mediated antiviral responses
-
Satoh T, et al. (2010) LGP2 is a positive regulator of RIG-I and MDA5-mediated antiviral responses. Proc Natl Acad Sci USA 107(4):1512-1517.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.4
, pp. 1512-1517
-
-
Satoh, T.1
-
34
-
-
84872604349
-
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5
-
Wu B, et al. (2012) Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5. Cell 152(1-2):276-289.
-
(2012)
Cell
, vol.152
, Issue.1-2
, pp. 276-289
-
-
Wu, B.1
-
35
-
-
39649092731
-
Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses
-
Takahasi K, et al. (2008) Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell 29(4):428-440.
-
(2008)
Mol Cell
, vol.29
, Issue.4
, pp. 428-440
-
-
Takahasi, K.1
-
36
-
-
48949094095
-
Structural mechanism of RNA recognition by the RIG-Ilike receptors
-
Yoneyama M, Fujita T (2008) Structural mechanism of RNA recognition by the RIG-Ilike receptors. Immunity 29(2):178-181.
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 178-181
-
-
Yoneyama, M.1
Fujita, T.2
-
37
-
-
77955481642
-
The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain
-
Lu C, et al. (2010) The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain. Structure 18(8):1032-1043.
-
(2010)
Structure
, vol.18
, Issue.8
, pp. 1032-1043
-
-
Lu, C.1
-
38
-
-
31044452870
-
Functional proteomics reveals the biochemical niche of C. Elegans DCR-1 in multiple small-RNA-mediated pathways
-
Duchaine TF, et al. (2006) Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell 124(2):343-354.
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 343-354
-
-
Duchaine, T.F.1
-
39
-
-
70349459257
-
The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation
-
Claycomb JM, et al. (2009) The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 139(1):123-134.
-
(2009)
Cell
, vol.139
, Issue.1
, pp. 123-134
-
-
Claycomb, J.M.1
-
40
-
-
76249103869
-
Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs
-
Wu Q, et al. (2010) Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs. Proc Natl Acad Sci USA 107(4):1606-1611.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.4
, pp. 1606-1611
-
-
Wu, Q.1
-
41
-
-
33750824034
-
Analysis of the C elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi
-
Yigit E, et al. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell 127(4):747-757.
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 747-757
-
-
Yigit, E.1
-
42
-
-
77649239548
-
Six RNA viruses and forty-one hosts: Viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems
-
Parameswaran P, et al. (2010) Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems. PLoS Pathog 6(2):e1000764.
-
(2010)
PLoS Pathog
, vol.6
, Issue.2
-
-
Parameswaran, P.1
-
43
-
-
84869054585
-
Silencing of host genes directed by virus-derived short interfering RNAs in Caenorhabditis elegans
-
Guo X, Li W-X, Lu R (2012) Silencing of host genes directed by virus-derived short interfering RNAs in Caenorhabditis elegans. J Virol 86(21):11645-11653.
-
(2012)
J Virol
, vol.86
, Issue.21
, pp. 11645-11653
-
-
Guo, X.1
Li, W.-X.2
Lu, R.3
-
45
-
-
84870359715
-
Recognition of viruses in the cytoplasm by RLRs and other helicases-how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses
-
Ng CS, Kato H, Fujita T (2012) Recognition of viruses in the cytoplasm by RLRs and other helicases-how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses. Int Immunol 24(12):739-749.
-
(2012)
Int Immunol
, vol.24
, Issue.12
, pp. 739-749
-
-
Ng, C.S.1
Kato, H.2
Fujita, T.3
-
46
-
-
84877325148
-
Characterization of virus-encoded RNA interference suppressors in Caenorhabditis elegans
-
Guo X, Lu R (2013) Characterization of virus-encoded RNA interference suppressors in Caenorhabditis elegans. J Virol 87(10):5414-5423.
-
(2013)
J Virol
, vol.87
, Issue.10
, pp. 5414-5423
-
-
Guo, X.1
Lu, R.2
-
47
-
-
79957761869
-
The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana
-
Wang X-B, et al. (2011) The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potent antiviral defense by two cooperative argonautes in Arabidopsis thaliana. Plant Cell 23(4):1625-1638.
-
(2011)
Plant Cell
, vol.23
, Issue.4
, pp. 1625-1638
-
-
Wang, X.-B.1
|