Hierarchical action and inhibition of plant dicer-like proteins in antiviral defense

Science

Volumn 313, Issue 5783, 2006, Pages 68-71

  Deleris, Angélique ^a   Gallago Bartolome, Javier ^a   Bao, Jinsong ^b   Kasschau, Kristin D ^b   Carrington, James C ^b   Voinnet, Olivier ^a  

^a INST DE BIOL MOLEC DES PLANTES   (France)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DOSAGE; HIERARCHICAL SYSTEMS; IMMUNOLOGY; MOLECULAR STRUCTURE; PLANTS (BOTANY); RNA;

ANTIVIRAL DEFENSE; ARABIDOPSIS DICER-LIKE 4 (DCL4) PROGRAM; SUPPRESSOR-DEFICIENT VIRUSES; VIRAL-ENCODED SUPPRESSORS;

PROTEINS;

DCL2 PROTEIN; DCL4 PROTEIN; DICER LIKE PROTEIN; RIBONUCLEASE; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ANTIPARASITE DEFENSE; ENZYME ACTIVITY; IMMUNITY; INHIBITION; RNA; VIRUS;

ANTIVIRAL ACTIVITY; ARABIDOPSIS; ARTICLE; GENE SILENCING; NONHUMAN; PLANT DEFENSE; PLANT VIRUS; PRIORITY JOURNAL; PROTEIN FUNCTION; VIRUS IMMUNITY; VIRUS LOAD;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARMOVIRUS; CELL CYCLE PROTEINS; GREEN FLUORESCENT PROTEINS; MUTATION; PLANT DISEASES; PLANT LEAVES; PLANT VIRUSES; PLANTS, GENETICALLY MODIFIED; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE III; RIBONUCLEASES; RNA INTERFERENCE; RNA VIRUSES; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; RNA, VIRAL; RNA-INDUCED SILENCING COMPLEX; SIGNAL TRANSDUCTION; VIRAL PROTEINS;

ARABIDOPSIS;

EID: 33745916446     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1128214     Document Type: Article

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20. We thank members of the Voinnet laboratory for discussions and Z. Xie for dcl seeds. Funded by CNRS grant to A.D.; NSF grant MCB-0209836, NIH grant AI43288, and U.S. Department of Agriculture grant NRI 2005-35319-15280 to J.C.; and Pao Schloarship (Zhejiang University, China) to J.B. This work is dedicated to the memory of M. and G. Voinnet.