-
1
-
-
0018546766
-
Speculations on the evolution of sterol structure and function
-
K.E. Bloch Speculations on the evolution of sterol structure and function CRC Critical Reviews in Biochemistry 7 1979 1 5
-
(1979)
CRC Critical Reviews in Biochemistry
, vol.7
, pp. 1-5
-
-
Bloch, K.E.1
-
2
-
-
68449100944
-
Special relationship between sterols and oxygen: Were sterols an adaptation to aerobic life
-
A.M. Galea, and A.J. Brown Special relationship between sterols and oxygen: were sterols an adaptation to aerobic life Free Radical Biology and Medicine 47 2009 880 889
-
(2009)
Free Radical Biology and Medicine
, vol.47
, pp. 880-889
-
-
Galea, A.M.1
Brown, A.J.2
-
3
-
-
0036732030
-
Cholesterol in health and disease
-
DOI 10.1172/JCI200216381
-
I. Tabas Cholesterol in health and disease Journal of Clinical Investigation 110 2002 583 590 (Pubitemid 34988779)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.5
, pp. 583-590
-
-
Tabas, I.1
-
4
-
-
0023277160
-
6 double bond in cholesterol
-
DOI 10.1021/bi00383a005
-
G.N. Ranadive, and A.K. Lala Sterol-phospholipid interaction in model membranes: role of c5-c6 double bond in cholesterol Biochemistry 26 1987 2426 2431 (Pubitemid 17081470)
-
(1987)
Biochemistry
, vol.26
, Issue.9
, pp. 2426-2431
-
-
Ranadive, G.N.1
Lala, A.K.2
-
5
-
-
12344270987
-
What's so special about cholesterol
-
O.G. Mouritsen, and M.J. Zuckermann What's so special about cholesterol Lipids 39 2004 1101 1113
-
(2004)
Lipids
, vol.39
, pp. 1101-1113
-
-
Mouritsen, O.G.1
Zuckermann, M.J.2
-
6
-
-
68749118353
-
Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3t3-l1 preadipocytes
-
J. Sanchez-Wandelmer, A. Davalos, E. Herrera, M. Giera, S. Cano, and G. de la Pena Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3t3-l1 preadipocytes Biochimica et Biophysica Acta 1788 2009 1731 1739
-
(2009)
Biochimica et Biophysica Acta
, vol.1788
, pp. 1731-1739
-
-
Sanchez-Wandelmer, J.1
Davalos, A.2
Herrera, E.3
Giera, M.4
Cano, S.5
De La Pena, G.6
-
7
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
DOI 10.1126/science.290.5497.1771
-
K.E. Berge, H. Tian, G.A. Graf, L. Yu, N.V. Grishin, and J. Schultz Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent abc transporters Science 290 2000 1771 1775 (Pubitemid 32004809)
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1771-1775
-
-
Berge, K.E.1
Tian, H.2
Graf, G.A.3
Yu, L.4
Grishin, N.V.5
Schultz, J.6
Kwiterovich, P.7
Shan, B.8
Barnes, R.9
Hobbs, H.H.10
-
8
-
-
3543104951
-
Cholesterol metabolism in the central nervous system during early development and in the mature animal
-
DOI 10.1194/jlr.R400004-JLR200
-
J.M. Dietschy, and S.D. Turley Thematic review series: brain lipids cholesterol metabolism in the central nervous system during early development and in the mature animal Journal of Lipid Research 45 2004 1375 1397 (Pubitemid 39022664)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.8
, pp. 1375-1397
-
-
Dietschy, J.M.1
Turley, S.D.2
-
10
-
-
66349134748
-
Cholesterol feedback: From schoenheimer's bottle to scap's meladl
-
M.S. Brown, and J.L. Goldstein Cholesterol feedback: from schoenheimer's bottle to scap's meladl Journal of Lipid Research 50 Suppl. 2009 S15 S27
-
(2009)
Journal of Lipid Research
, vol.50
, Issue.SUPPL.
-
-
Brown, M.S.1
Goldstein, J.L.2
-
11
-
-
61449111827
-
The evolution of plasma cholesterol: Direct utility or a spandrel of hepatic lipid metabolism
-
P.J. Babin, and G.F. Gibbons The evolution of plasma cholesterol: direct utility or a spandrel of hepatic lipid metabolism Progress in Lipid Research 48 2009 73 91
-
(2009)
Progress in Lipid Research
, vol.48
, pp. 73-91
-
-
Babin, P.J.1
Gibbons, G.F.2
-
12
-
-
0027501003
-
Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
-
J.M. Dietschy, S.D. Turley, and D.K. Spady Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans Journal of Lipid Research 34 1993 1637 1659 (Pubitemid 23298709)
-
(1993)
Journal of Lipid Research
, vol.34
, Issue.10
, pp. 1637-1659
-
-
Dietschy, J.M.1
Turley, S.D.2
Spady, D.K.3
-
13
-
-
84866155091
-
Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein
-
C.L. Vrins, R. Ottenhoff, K. van den Oever, D.R. de Waart, J.K. Kruyt, and Y. Zhao Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein Journal of Lipid Research 53 2012 2017 2023
-
(2012)
Journal of Lipid Research
, vol.53
, pp. 2017-2023
-
-
Vrins, C.L.1
Ottenhoff, R.2
Van Den Oever, K.3
De Waart, D.R.4
Kruyt, J.K.5
Zhao, Y.6
-
14
-
-
84862804992
-
Biliary and nonbiliary contributions to reverse cholesterol transport
-
R.E. Temel, and J.M. Brown Biliary and nonbiliary contributions to reverse cholesterol transport Current Opinion in Lipidology 23 2012 85 90
-
(2012)
Current Opinion in Lipidology
, vol.23
, pp. 85-90
-
-
Temel, R.E.1
Brown, J.M.2
-
15
-
-
79955535643
-
Macrophages in the pathogenesis of atherosclerosis
-
K.J. Moore, and I. Tabas Macrophages in the pathogenesis of atherosclerosis Cell 145 2011 341 355
-
(2011)
Cell
, vol.145
, pp. 341-355
-
-
Moore, K.J.1
Tabas, I.2
-
16
-
-
1842584883
-
Rna regulation: A new genetics
-
J.S. Mattick Rna regulation: a new genetics Nature Reviews Genetics 5 2004 316 323
-
(2004)
Nature Reviews Genetics
, vol.5
, pp. 316-323
-
-
Mattick, J.S.1
-
17
-
-
0035195942
-
Non-coding RNAs: The architects of eukaryotic complexity
-
DOI 10.1093/embo-reports/kve230
-
J.S. Mattick Non-coding rnas: the architects of eukaryotic complexity EMBO Reports 2 2001 986 991 (Pubitemid 33130603)
-
(2001)
EMBO Reports
, vol.2
, Issue.11
, pp. 986-991
-
-
Mattick, J.S.1
-
18
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
I. Dunham, A. Kundaje, S.F. Aldred, P.J. Collins, C.A. Davis, and F. Doyle An integrated encyclopedia of DNA elements in the human genome Nature 489 2012 57 74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
Kundaje, A.2
Aldred, S.F.3
Collins, P.J.4
Davis, C.A.5
Doyle, F.6
-
19
-
-
84865757142
-
Landscape of transcription in human cells
-
S. Djebali, C.A. Davis, A. Merkel, A. Dobin, T. Lassmann, and A. Mortazavi Landscape of transcription in human cells Nature 489 2012 101 108
-
(2012)
Nature
, vol.489
, pp. 101-108
-
-
Djebali, S.1
Davis, C.A.2
Merkel, A.3
Dobin, A.4
Lassmann, T.5
Mortazavi, A.6
-
20
-
-
84865812140
-
Encode project writes eulogy for junk DNA
-
Pennisi E. Genomics Encode project writes eulogy for junk DNA Science 337 1159 2012 1161
-
(2012)
Science
, vol.337
, Issue.1159
, pp. 1161
-
-
Genomics, P.E.1
-
21
-
-
84858379476
-
Micrornas in stress signaling and human disease
-
J.T. Mendell, and E.N. Olson Micrornas in stress signaling and human disease Cell 148 2012 1172 1187
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
23
-
-
77953787211
-
Mir-33 contributes to the regulation of cholesterol homeostasis
-
K.J. Rayner, Y. Suarez, A. Davalos, S. Parathath, M.L. Fitzgerald, and N. Tamehiro Mir-33 contributes to the regulation of cholesterol homeostasis Science 328 2010 1570 1573
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
Suarez, Y.2
Davalos, A.3
Parathath, S.4
Fitzgerald, M.L.5
Tamehiro, N.6
-
25
-
-
84858796689
-
Transcriptional integration of metabolism by the nuclear sterol-activated receptors lxr and fxr
-
A.C. Calkin, and P. Tontonoz Transcriptional integration of metabolism by the nuclear sterol-activated receptors lxr and fxr Nature Reviews Molecular Cell Biology 13 2012 213 224
-
(2012)
Nature Reviews Molecular Cell Biology
, vol.13
, pp. 213-224
-
-
Calkin, A.C.1
Tontonoz, P.2
-
26
-
-
84867405858
-
Transcriptional and posttranscriptional control of cholesterol homeostasis by liver × receptors
-
P. Tontonoz Transcriptional and posttranscriptional control of cholesterol homeostasis by liver × receptors Cold Spring Harbor Symposia on Quantitative Biology 76 2011 129 137
-
(2011)
Cold Spring Harbor Symposia on Quantitative Biology
, vol.76
, pp. 129-137
-
-
Tontonoz, P.1
-
27
-
-
10744221008
-
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
-
DOI 10.1126/science.1093131
-
S.W. Altmann, H.R. Davis Jr., L.J. Zhu, X. Yao, L.M. Hoos, and G. Tetzloff Niemann-pick c1 like 1 protein is critical for intestinal cholesterol absorption Science 303 2004 1201 1204 (Pubitemid 38233587)
-
(2004)
Science
, vol.303
, Issue.5661
, pp. 1201-1204
-
-
Altmann, S.W.1
Davis Jr., H.R.2
Zhu, L.-J.3
Yao, X.4
Hoos, L.M.5
Tetzloff, G.6
Iyer, S.P.N.7
Maguire, M.8
Golovko, A.9
Zeng, M.10
Wang, L.11
Murgolo, N.12
Graziano, M.P.13
-
28
-
-
59949088249
-
Lowering low-density lipoprotein cholesterol: Statins, ezetimibe, bile acid sequestrants, and combinations: Comparative efficacy and safety
-
R. Hou, and A.C. Goldberg Lowering low-density lipoprotein cholesterol: statins, ezetimibe, bile acid sequestrants, and combinations: comparative efficacy and safety Endocrinology and Metabolism Clinics of North America 38 2009 79 97
-
(2009)
Endocrinology and Metabolism Clinics of North America
, vol.38
, pp. 79-97
-
-
Hou, R.1
Goldberg, A.C.2
-
29
-
-
0015024159
-
Effects of dietary cholesterol on the regulation of total body cholesterol in man
-
E. Quintao, S.M. Grundy, and E.H. Ahrens Jr. Effects of dietary cholesterol on the regulation of total body cholesterol in man Journal of Lipid Research 12 1971 233 247
-
(1971)
Journal of Lipid Research
, vol.12
, pp. 233-247
-
-
Quintao, E.1
Grundy, S.M.2
Ahrens, Jr.E.H.3
-
30
-
-
0024511609
-
Cholesterol absorption: Regulation of cholesterol synthesis and elimination and within-population variations of serum cholesterol levels
-
T.A. Miettinen, and Y.A. Kesaniemi Cholesterol absorption: regulation of cholesterol synthesis and elimination and within-population variations of serum cholesterol levels American Journal of Clinical Nutrition 49 1989 629 635 (Pubitemid 19107282)
-
(1989)
American Journal of Clinical Nutrition
, vol.49
, Issue.4
, pp. 629-635
-
-
Miettinen, T.A.1
Kesaniemi, Y.A.2
-
31
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
DOI 10.1172/JCI200215593
-
J.D. Horton, J.L. Goldstein, and Brown M.S. Srebps Activators of the complete program of cholesterol and fatty acid synthesis in the liver Journal of Clinical Investigation 109 2002 1125 1131 (Pubitemid 34496588)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.9
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
32
-
-
84868518061
-
Apolipoprotein b synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: Results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease
-
E.A. Stein, R. Dufour, C. Gagne, D. Gaudet, C. East, and J.M. Donovan Apolipoprotein b synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: Results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease Circulation 126 2012 2283 2292
-
(2012)
Circulation
, vol.126
, pp. 2283-2292
-
-
Stein, E.A.1
Dufour, R.2
Gagne, C.3
Gaudet, D.4
East, C.5
Donovan, J.M.6
-
33
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
M.S. Brown, and J.L. Goldstein A receptor-mediated pathway for cholesterol homeostasis Science 232 1986 34 47 (Pubitemid 16037973)
-
(1986)
Science
, vol.232
, Issue.4746
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
34
-
-
84871871419
-
Feedback regulation of cholesterol uptake by the lxr-idol-ldlr axis
-
L. Zhang, K. Reue, L.G. Fong, S.G. Young, and P. Tontonoz Feedback regulation of cholesterol uptake by the lxr-idol-ldlr axis Arteriosclerosis, Thrombosis, and Vascular Biology 32 2012 2541 2546
-
(2012)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.32
, pp. 2541-2546
-
-
Zhang, L.1
Reue, K.2
Fong, L.G.3
Young, S.G.4
Tontonoz, P.5
-
35
-
-
9644266673
-
Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver
-
DOI 10.1074/jbc.M410077200
-
S.W. Park, Y.A. Moon, and J.D. Horton Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver Journal of Biological Chemistry 279 2004 50630 50638 (Pubitemid 39577880)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.48
, pp. 50630-50638
-
-
Sahng, W.P.1
Moon, Y.-A.2
Horton, J.D.3
-
36
-
-
67650092919
-
Lxr regulates cholesterol uptake through idol-dependent ubiquitination of the ldl receptor
-
N. Zelcer, C. Hong, R. Boyadjian, and P. Tontonoz Lxr regulates cholesterol uptake through idol-dependent ubiquitination of the ldl receptor Science 325 2009 100 104
-
(2009)
Science
, vol.325
, pp. 100-104
-
-
Zelcer, N.1
Hong, C.2
Boyadjian, R.3
Tontonoz, P.4
-
37
-
-
66349126280
-
Pcsk9. A convertase that coordinates ldl catabolism
-
J.D. Horton, J.C. Cohen, and H.H. Hobbs Pcsk9. A convertase that coordinates ldl catabolism Journal of Lipid Research 50 SupplS1 2009 72 177
-
(2009)
Journal of Lipid Research
, vol.50
, Issue.SUPPL. S1
, pp. 72-177
-
-
Horton, J.D.1
Cohen, J.C.2
Hobbs, H.H.3
-
38
-
-
38949137409
-
Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2
-
DOI 10.1194/jlr.M700443-JLR200
-
H.J. Jeong, H.S. Lee, K.S. Kim, Y.K. Kim, D. Yoon, and S.W. Park Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2 Journal of Lipid Research 49 2008 399 409 (Pubitemid 351213625)
-
(2008)
Journal of Lipid Research
, vol.49
, Issue.2
, pp. 399-409
-
-
Hyun, J.J.1
Lee, H.-S.2
Kim, K.-S.3
Kim, Y.-K.4
Yoon, D.5
Sahng, W.P.6
-
39
-
-
84870494510
-
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (mendel): A randomised, double-blind, placebo-controlled, phase 2 study
-
M.J. Koren, R. Scott, J.B. Kim, B. Knusel, T. Liu, and L. Lei Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (mendel): a randomised, double-blind, placebo-controlled, phase 2 study Lancet 380 2012 1995 2006
-
(2012)
Lancet
, vol.380
, pp. 1995-2006
-
-
Koren, M.J.1
Scott, R.2
Kim, J.B.3
Knusel, B.4
Liu, T.5
Lei, L.6
-
40
-
-
17244377696
-
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
-
DOI 10.1073/pnas.0501652102
-
S. Rashid, D.E. Curtis, R. Garuti, N.N. Anderson, Y. Bashmakov, and Y.K. Ho Decreased plasma cholesterol and hypersensitivity to statins in mice lacking pcsk9 Proceedings of the National Academy of Sciences of the United States of America 102 2005 5374 5379 (Pubitemid 40530265)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.15
, pp. 5374-5379
-
-
Rashid, S.1
Curtis, D.E.2
Garuti, R.3
Anderson, N.H.4
Bashmakov, Y.5
Ho, Y.K.6
Hammer, R.E.7
Moon, Y.-A.8
Horton, J.D.9
-
41
-
-
67049144914
-
Safety, pharmacokinetics, and pharmacodynamics of single doses of lxr-623, a novel liver x-receptor agonist, in healthy participants
-
A. Katz, C. Udata, E. Ott, L. Hickey, M.E. Burczynski, and P. Burghart Safety, pharmacokinetics, and pharmacodynamics of single doses of lxr-623, a novel liver x-receptor agonist, in healthy participants Journal of Clinical Pharmacology 49 2009 643 649
-
(2009)
Journal of Clinical Pharmacology
, vol.49
, pp. 643-649
-
-
Katz, A.1
Udata, C.2
Ott, E.3
Hickey, L.4
Burczynski, M.E.5
Burghart, P.6
-
43
-
-
0014264541
-
The plasma lecithins: Cholesterol acyltransferase reaction
-
J.A. Glomset The plasma lecithins: cholesterol acyltransferase reaction Journal of Lipid Research 9 1968 155 167
-
(1968)
Journal of Lipid Research
, vol.9
, pp. 155-167
-
-
Glomset, J.A.1
-
44
-
-
51149117412
-
Regulation of direct transintestinal cholesterol excretion in mice
-
A.E. van der Velde, C.L. Vrins, K. van den Oever, R.P. Oude Elferink, M. van Eck, and F. Kuipers Regulation of direct transintestinal cholesterol excretion in mice American Journal of Physiology-Gastrointestinal and Liver Physiology 295 2008 G203 G208
-
(2008)
American Journal of Physiology-Gastrointestinal and Liver Physiology
, vol.295
-
-
Van Der Velde, A.E.1
Vrins, C.L.2
Van Den Oever, K.3
Oude Elferink, R.P.4
Van Eck, M.5
Kuipers, F.6
-
45
-
-
33644865172
-
Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
-
DOI 10.1161/CIRCULATIONAHA.105.560177, PII 0000301720060103000015
-
S.U. Naik, X. Wang, J.S. Da Silva, M. Jaye, C.H. Macphee, and M.P. Reilly Pharmacological activation of liver x receptors promotes reverse cholesterol transport in vivo Circulation 113 2006 90 97 (Pubitemid 43958493)
-
(2006)
Circulation
, vol.113
, Issue.1
, pp. 90-97
-
-
Naik, S.U.1
Wang, X.2
Da Silva, J.S.3
Jaye, M.4
Macphee, C.H.5
Reilly, M.P.6
Billheimer, J.T.7
Rothblat, G.H.8
Rader, D.J.9
-
46
-
-
0037188553
-
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
-
DOI 10.1073/pnas.112059299
-
S.B. Joseph, E. McKilligin, L. Pei, M.A. Watson, A.R. Collins, and B.A. Laffitte Synthetic lxr ligand inhibits the development of atherosclerosis in mice Proceedings of the National Academy of Sciences of the United States of America 99 2002 7604 7609 (Pubitemid 34568738)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.11
, pp. 7604-7609
-
-
Joseph, S.B.1
McKilligin, E.2
Pei, L.3
Watson, M.A.4
Collins, A.R.5
Laffitte, B.A.6
Chen, M.7
Noh, G.8
Goodman, J.9
Hagger, G.N.10
Tran, J.11
Tippin, T.K.12
Wang, X.13
Lusis, A.J.14
Hsueh, W.A.15
Law, R.E.16
Collins, J.L.17
Willson, T.M.18
Tontonoz, P.19
-
47
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
DOI 10.1073/pnas.252582399
-
L. Yu, R.E. Hammer, J. Li-Hawkins, K. Von Bergmann, D. Lutjohann, and J.C. Cohen Disruption of abcg5 and abcg8 in mice reveals their crucial role in biliary cholesterol secretion Proceedings of the National Academy of Sciences of the United States of America 99 2002 16237 16242 (Pubitemid 35462779)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16237-16242
-
-
Yu, L.1
Hammer, R.E.2
Li-Hawkins, J.3
Von Bergmann, K.4
Lutjohann, D.5
Cohen, J.C.6
Hobbs, H.H.7
-
48
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
DOI 10.1172/JCI200216001
-
L. Yu, J. Li-Hawkins, R.E. Hammer, K.E. Berge, J.D. Horton, and J.C. Cohen Overexpression of abcg5 and abcg8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol Journal of Clinical Investigation 110 2002 671 680 (Pubitemid 34988791)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.5
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
Berge, K.E.4
Horton, J.D.5
Cohen, J.C.6
Hobbs, H.H.7
-
49
-
-
67749110331
-
Activation of the liver x receptor stimulates trans-intestinal excretion of plasma cholesterol
-
J.N. van der Veen, T.H. van Dijk, C.L. Vrins, H. van Meer, R. Havinga, and K. Bijsterveld Activation of the liver x receptor stimulates trans-intestinal excretion of plasma cholesterol Journal of Biological Chemistry 284 2009 19211 19219
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 19211-19219
-
-
Van Der Veen, J.N.1
Van Dijk, T.H.2
Vrins, C.L.3
Van Meer, H.4
Havinga, R.5
Bijsterveld, K.6
-
50
-
-
77956642596
-
Biliary sterol secretion is not required for macrophage reverse cholesterol transport
-
R.E. Temel, J.K. Sawyer, L. Yu, C. Lord, C. Degirolamo, and A. McDaniel Biliary sterol secretion is not required for macrophage reverse cholesterol transport Cell Metabolism 12 2010 96 102
-
(2010)
Cell Metabolism
, vol.12
, pp. 96-102
-
-
Temel, R.E.1
Sawyer, J.K.2
Yu, L.3
Lord, C.4
Degirolamo, C.5
McDaniel, A.6
-
51
-
-
77956820329
-
Sr-bi, cd36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells
-
T.Q. Truong, D. Aubin, L. Falstrault, M.R. Brodeur, and L. Brissette Sr-bi, cd36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells Cell Biochemistry and Function 28 2010 480 489
-
(2010)
Cell Biochemistry and Function
, vol.28
, pp. 480-489
-
-
Truong, T.Q.1
Aubin, D.2
Falstrault, L.3
Brodeur, M.R.4
Brissette, L.5
-
52
-
-
34547700634
-
Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo
-
DOI 10.1172/JCI32057
-
X. Wang, H.L. Collins, M. Ranalletta, I.V. Fuki, J.T. Billheimer, and G.H. Rothblat Macrophage abca1 and abcg1, but not sr-bi, promote macrophage reverse cholesterol transport in vivo Journal of Clinical Investigation 117 2007 2216 2224 (Pubitemid 47219566)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2216-2224
-
-
Wang, X.1
Collins, H.L.2
Ranalletta, M.3
Fuki, I.V.4
Billheimer, J.T.5
Rothblat, G.H.6
Tall, A.R.7
Rader, D.J.8
-
53
-
-
0035882167
-
Apolipoprotein A-I stimulates the transport of intracellular cholesterol to cell-surface cholesterol-rich domains (caveolae)
-
DOI 10.1042/0264-6021:3580079
-
D. Sviridov, N. Fidge, G. Beaumier-Gallon, and C. Fielding Apolipoprotein a-i stimulates the transport of intracellular cholesterol to cell-surface cholesterol-rich domains (caveolae) Biochemical Journal 358 2001 79 86 (Pubitemid 32778100)
-
(2001)
Biochemical Journal
, vol.358
, Issue.1
, pp. 79-86
-
-
Sviridov, D.1
Fidge, N.2
Beaumier-Gallon, G.3
Fielding, C.4
-
54
-
-
0035039158
-
Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins
-
P.G. Frank, F. Galbiati, D. Volonte, B. Razani, D.E. Cohen, and Y.L. Marcel Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins American Journal of Physiology-Cell Physiology 280 2001 C1204 C1214
-
(2001)
American Journal of Physiology-Cell Physiology
, vol.280
-
-
Frank, P.G.1
Galbiati, F.2
Volonte, D.3
Razani, B.4
Cohen, D.E.5
Marcel, Y.L.6
-
55
-
-
80051621749
-
Caveolin-1-mediated apolipoprotein a-i membrane binding sites are not required for cholesterol efflux
-
S. Le Lay, M. Rodriguez, W. Jessup, C. Rentero, Q. Li, and S. Cartland Caveolin-1-mediated apolipoprotein a-i membrane binding sites are not required for cholesterol efflux PLoS One 6 2011 e23353
-
(2011)
PLoS One
, vol.6
, pp. 23353
-
-
Le Lay, S.1
Rodriguez, M.2
Jessup, W.3
Rentero, C.4
Li, Q.5
Cartland, S.6
-
56
-
-
79958030075
-
Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase
-
M. Ouimet, V. Franklin, E. Mak, X. Liao, I. Tabas, and Y.L. Marcel Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase Cell Metabolism 13 2011 655 667
-
(2011)
Cell Metabolism
, vol.13
, pp. 655-667
-
-
Ouimet, M.1
Franklin, V.2
Mak, E.3
Liao, X.4
Tabas, I.5
Marcel, Y.L.6
-
57
-
-
33745132444
-
Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
-
DOI 10.1161/CIRCULATIONAHA.104.475715, PII 0000301720060530000014
-
M. Cuchel, and D.J. Rader Macrophage reverse cholesterol transport: key to the regression of atherosclerosis Circulation 113 2006 2548 2555 (Pubitemid 43948034)
-
(2006)
Circulation
, vol.113
, Issue.21
, pp. 2548-2555
-
-
Cuchel, M.1
Rader, D.J.2
-
58
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein
-
P.M. Ridker, E. Danielson, F.A. Fonseca, J. Genest, A.M. Gotto Jr., and J.J. Kastelein Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein New England Journal of Medicine 359 2008 2195 2207
-
(2008)
New England Journal of Medicine
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
Genest, J.4
Gotto, Jr.A.M.5
Kastelein, J.J.6
-
59
-
-
36549034768
-
Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths
-
S. Lewington, G. Whitlock, R. Clarke, P. Sherliker, J. Emberson, and J. Halsey Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths Lancet 370 2007 1829 1839
-
(2007)
Lancet
, vol.370
, pp. 1829-1839
-
-
Lewington, S.1
Whitlock, G.2
Clarke, R.3
Sherliker, P.4
Emberson, J.5
Halsey, J.6
-
60
-
-
36348975228
-
Effects of torcetrapib in patients at high risk for coronary events
-
DOI 10.1056/NEJMoa0706628
-
P.J. Barter, M. Caulfield, M. Eriksson, S.M. Grundy, J.J. Kastelein, and M. Komajda Effects of torcetrapib in patients at high risk for coronary events New England Journal of Medicine 357 2007 2109 2122 (Pubitemid 350146106)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.21
, pp. 2109-2122
-
-
Barter, P.J.1
Caulfield, M.2
Eriksson, M.3
Grundy, S.M.4
Kastelein, J.J.P.5
Komajda, M.6
Lopez-Sendon, J.7
Mosca, L.8
Tardif, J.-C.9
Waters, D.D.10
Shear, C.L.11
Revkin, J.H.12
Buhr, K.A.13
Fisher, M.R.14
Tall, A.R.15
Brewer, B.16
-
61
-
-
79953867783
-
Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: Systematic review and meta-regression analysis
-
M. Briel, I. Ferreira-Gonzalez, J.J. You, P.J. Karanicolas, E.A. Akl, and P. Wu Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis British Medical Journal 338 2009 b92
-
(2009)
British Medical Journal
, vol.338
, pp. 92
-
-
Briel, M.1
Ferreira-Gonzalez, I.2
You, J.J.3
Karanicolas, P.J.4
Akl, E.A.5
Wu, P.6
-
62
-
-
33645103550
-
Sequence variations in pcsk9, low ldl, and protection against coronary heart disease
-
J.C. Cohen, E. Boerwinkle, T.H. Mosley Jr., and H.H. Hobbs Sequence variations in pcsk9, low ldl, and protection against coronary heart disease New England Journal of Medicine 354 2006 1264 1272
-
(2006)
New England Journal of Medicine
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley, Jr.T.H.3
Hobbs, H.H.4
-
63
-
-
84864845456
-
Plasma hdl cholesterol and risk of myocardial infarction: A mendelian randomisation study
-
B.F. Voight, G.M. Peloso, M. Orho-Melander, R. Frikke-Schmidt, M. Barbalic, and M.K. Jensen Plasma hdl cholesterol and risk of myocardial infarction: a mendelian randomisation study Lancet 380 2012 572 580
-
(2012)
Lancet
, vol.380
, pp. 572-580
-
-
Voight, B.F.1
Peloso, G.M.2
Orho-Melander, M.3
Frikke-Schmidt, R.4
Barbalic, M.5
Jensen, M.K.6
-
64
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
G.G. Schwartz, A.G. Olsson, M. Abt, C.M. Ballantyne, P.J. Barter, and J. Brumm Effects of dalcetrapib in patients with a recent acute coronary syndrome New England Journal of Medicine 367 2012 2089 2099
-
(2012)
New England Journal of Medicine
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Abt, M.3
Ballantyne, C.M.4
Barter, P.J.5
Brumm, J.6
-
65
-
-
84855171302
-
Niacin in patients with low hdl cholesterol levels receiving intensive statin therapy
-
W.E. Boden, J.L. Probstfield, T. Anderson, B.R. Chaitman, P. Desvignes-Nickens, and K. Koprowicz Niacin in patients with low hdl cholesterol levels receiving intensive statin therapy New England Journal of Medicine 365 2011 2255 2267
-
(2011)
New England Journal of Medicine
, vol.365
, pp. 2255-2267
-
-
Boden, W.E.1
Probstfield, J.L.2
Anderson, T.3
Chaitman, B.R.4
Desvignes-Nickens, P.5
Koprowicz, K.6
-
66
-
-
77957340934
-
Proteomic characterization of human plasma high density lipoprotein fractionated by gel filtration chromatography
-
S.M. Gordon, J. Deng, L.J. Lu, and W.S. Davidson Proteomic characterization of human plasma high density lipoprotein fractionated by gel filtration chromatography Journal of Proteome Research 9 2010 5239 5249
-
(2010)
Journal of Proteome Research
, vol.9
, pp. 5239-5249
-
-
Gordon, S.M.1
Deng, J.2
Lu, L.J.3
Davidson, W.S.4
-
68
-
-
77950894330
-
The ability to promote efflux via abca1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages
-
M. de la Llera-Moya, D. Drazul-Schrader, B.F. Asztalos, M. Cuchel, D.J. Rader, and G.H. Rothblat The ability to promote efflux via abca1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages Arteriosclerosis, Thrombosis, and Vascular Biology 30 2010 796 801
-
(2010)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.30
, pp. 796-801
-
-
De La Llera-Moya, M.1
Drazul-Schrader, D.2
Asztalos, B.F.3
Cuchel, M.4
Rader, D.J.5
Rothblat, G.H.6
-
69
-
-
78651379500
-
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
-
A.V. Khera, M. Cuchel, M. de la Llera-Moya, A. Rodrigues, M.F. Burke, and K. Jafri Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis New England Journal of Medicine 364 2011 127 135
-
(2011)
New England Journal of Medicine
, vol.364
, pp. 127-135
-
-
Khera, A.V.1
Cuchel, M.2
De La Llera-Moya, M.3
Rodrigues, A.4
Burke, M.F.5
Jafri, K.6
-
70
-
-
84870048419
-
High-density lipoprotein function, dysfunction, and reverse cholesterol transport
-
E.A. Fisher, J.E. Feig, B. Hewing, S.L. Hazen, and J.D. Smith High-density lipoprotein function, dysfunction, and reverse cholesterol transport Arteriosclerosis, Thrombosis, and Vascular Biology 32 2012 2813 2820
-
(2012)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.32
, pp. 2813-2820
-
-
Fisher, E.A.1
Feig, J.E.2
Hewing, B.3
Hazen, S.L.4
Smith, J.D.5
-
71
-
-
0027751663
-
The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
DOI 10.1016/0092-8674(93)90529-Y
-
R.C. Lee, R.L. Feinbaum, and V. Ambros The c elegans heterochronic gene lin-4 encodes small rnas with antisense complementarity to lin-14 Cell 75 1993 843 854 (Pubitemid 24014542)
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
72
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. Elegans
-
DOI 10.1016/0092-8674(93)90530-4
-
B. Wightman, I. Ha, and G. Ruvkun Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in c Elegans Cell 75 1993 855 862 (Pubitemid 24014543)
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
73
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
DOI 10.1126/science.1064921
-
M. Lagos-Quintana, R. Rauhut, W. Lendeckel, and T. Tuschl Identification of novel genes coding for small expressed rnas Science 294 2001 853 858 (Pubitemid 33032103)
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
74
-
-
0036645146
-
MicroRNAs in plants
-
DOI 10.1101/gad.1004402
-
B.J. Reinhart, E.G. Weinstein, M.W. Rhoades, B. Bartel, and D.P. Bartel Micrornas in plants Genes and Development 16 2002 1616 1626 (Pubitemid 34743323)
-
(2002)
Genes and Development
, vol.16
, Issue.13
, pp. 1616-1626
-
-
Reinhart, B.J.1
Weinstein, E.G.2
Rhoades, M.W.3
Bartel, B.4
Bartel, D.P.5
-
75
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
DOI 10.1073/pnas.242606799
-
G.A. Calin, C.D. Dumitru, M. Shimizu, R. Bichi, S. Zupo, and E. Noch Frequent deletions and down-regulation of micro-rna genes mir15 and mir16 at 13q14 in chronic lymphocytic leukemia Proceedings of the National Academy of Sciences of the United States of America 99 2002 15524 15529 (Pubitemid 35403967)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.24
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
Aldler, H.7
Rattan, S.8
Keating, M.9
Rai, K.10
Rassenti, L.11
Kipps, T.12
Negrini, M.13
Bullrich, F.14
Croce, C.M.15
-
76
-
-
77955902024
-
The widespread regulation of microrna biogenesis, function and decay
-
J. Krol, I. Loedige, and W. Filipowicz The widespread regulation of microrna biogenesis, function and decay Nature Reviews Genetics 11 2010 597 610
-
(2010)
Nature Reviews Genetics
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
77
-
-
58249088751
-
Micrornas target recognition and regulatory functions
-
D.P. Bartel Micrornas target recognition and regulatory functions Cell 136 2009 215 233
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
78
-
-
77955644289
-
Mammalian micrornas predominantly act to decrease target mrna levels
-
H. Guo, N.T. Ingolia, J.S. Weissman, and D.P. Bartel Mammalian micrornas predominantly act to decrease target mrna levels Nature 466 2010 835 840
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
79
-
-
36749026906
-
Switching from repression to activation: Micrornas can up-regulate translation
-
S. Vasudevan, Y. Tong, and J.A. Steitz Switching from repression to activation: micrornas can up-regulate translation Science 318 2007 1931 1934
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
80
-
-
43449090367
-
MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
-
DOI 10.1016/j.molcel.2008.05.001, PII S1097276508003286
-
U.A. Orom, F.C. Nielsen, and A.H. Lund Microrna-10a binds the 5'utr of ribosomal protein mrnas and enhances their translation Molecular Cell 30 2008 460 471 (Pubitemid 351672378)
-
(2008)
Molecular Cell
, vol.30
, Issue.4
, pp. 460-471
-
-
Orom, U.A.1
Nielsen, F.C.2
Lund, A.H.3
-
81
-
-
54549108798
-
Micrornas to nanog, oct4 and sox2 coding regions modulate embryonic stem cell differentiation
-
Y. Tay, J. Zhang, A.M. Thomson, B. Lim, and I. Rigoutsos Micrornas to nanog, oct4 and sox2 coding regions modulate embryonic stem cell differentiation Nature 455 2008 1124 1128
-
(2008)
Nature
, vol.455
, pp. 1124-1128
-
-
Tay, Y.1
Zhang, J.2
Thomson, A.M.3
Lim, B.4
Rigoutsos, I.5
-
83
-
-
0037197803
-
Identification of tissue-specific MicroRNAs from mouse
-
DOI 10.1016/S0960-9822(02)00809-6, PII S0960982202008096
-
M. Lagos-Quintana, R. Rauhut, A. Yalcin, J. Meyer, W. Lendeckel, and T. Tuschl Identification of tissue-specific micrornas from mouse Current Biology 12 2002 735 739 (Pubitemid 34455427)
-
(2002)
Current Biology
, vol.12
, Issue.9
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
84
-
-
78751660177
-
Pervasive roles of micrornas in cardiovascular biology
-
E.M. Small, and E.N. Olson Pervasive roles of micrornas in cardiovascular biology Nature 469 2011 336 342
-
(2011)
Nature
, vol.469
, pp. 336-342
-
-
Small, E.M.1
Olson, E.N.2
-
85
-
-
77953957633
-
A coding-independent function of gene and pseudogene mrnas regulates tumour biology
-
L. Poliseno, L. Salmena, J. Zhang, B. Carver, W.J. Haveman, and P.P. Pandolfi A coding-independent function of gene and pseudogene mrnas regulates tumour biology Nature 465 2010 1033 1038
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
86
-
-
80054715378
-
A long noncoding rna controls muscle differentiation by functioning as a competing endogenous rna
-
M. Cesana, D. Cacchiarelli, I. Legnini, T. Santini, O. Sthandier, and M. Chinappi A long noncoding rna controls muscle differentiation by functioning as a competing endogenous rna Cell 147 2011 358 369
-
(2011)
Cell
, vol.147
, pp. 358-369
-
-
Cesana, M.1
Cacchiarelli, D.2
Legnini, I.3
Santini, T.4
Sthandier, O.5
Chinappi, M.6
-
87
-
-
79961170994
-
A cerna hypothesis: The rosetta stone of a hidden rna language
-
L. Salmena, L. Poliseno, Y. Tay, L. Kats, and P.P. Pandolfi A cerna hypothesis: the rosetta stone of a hidden rna language Cell 146 2011 353 358
-
(2011)
Cell
, vol.146
, pp. 353-358
-
-
Salmena, L.1
Poliseno, L.2
Tay, Y.3
Kats, L.4
Pandolfi, P.P.5
-
89
-
-
54149095553
-
Biological principles of microrna-mediated regulation: Shared themes amid diversity
-
A.S. Flynt, and E.C. Lai Biological principles of microrna-mediated regulation: shared themes amid diversity Nature Reviews Genetics 9 2008 831 842
-
(2008)
Nature Reviews Genetics
, vol.9
, pp. 831-842
-
-
Flynt, A.S.1
Lai, E.C.2
-
90
-
-
55449100829
-
Toward microrna-based therapeutics for heart disease: The sense in antisense
-
E. van Rooij, W.S. Marshall, and E.N. Olson Toward microrna-based therapeutics for heart disease: the sense in antisense Circulation Research 103 2008 919 928
-
(2008)
Circulation Research
, vol.103
, pp. 919-928
-
-
Van Rooij, E.1
Marshall, W.S.2
Olson, E.N.3
-
92
-
-
84868475728
-
Microrna therapeutics for cardiovascular disease: Opportunities and obstacles
-
E. van Rooij, and E.N. Olson Microrna therapeutics for cardiovascular disease: opportunities and obstacles Nature Reviews Drug Discovery 11 2012 860 872
-
(2012)
Nature Reviews Drug Discovery
, vol.11
, pp. 860-872
-
-
Van Rooij, E.1
Olson, E.N.2
-
93
-
-
67349223927
-
Mutations in the seed region of human mir-96 are responsible for nonsyndromic progressive hearing loss
-
A. Mencia, S. Modamio-Hoybjor, N. Redshaw, M. Morin, F. Mayo-Merino, and L. Olavarrieta Mutations in the seed region of human mir-96 are responsible for nonsyndromic progressive hearing loss Nature Genetics 41 2009 609 613
-
(2009)
Nature Genetics
, vol.41
, pp. 609-613
-
-
Mencia, A.1
Modamio-Hoybjor, S.2
Redshaw, N.3
Morin, M.4
Mayo-Merino, F.5
Olavarrieta, L.6
-
94
-
-
77952918274
-
Genetic variation in microrna networks: The implications for cancer research
-
B.M. Ryan, A.I. Robles, and C.C. Harris Genetic variation in microrna networks: the implications for cancer research Nature Reviews Cancer 10 2010 389 402
-
(2010)
Nature Reviews Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
95
-
-
84861902017
-
Lipid-based nanoparticle delivery of pre-mir-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma
-
L. Piao, M. Zhang, J. Datta, X. Xie, T. Su, and H. Li Lipid-based nanoparticle delivery of pre-mir-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma Molecular Therapy 20 2012 1261 1269
-
(2012)
Molecular Therapy
, vol.20
, pp. 1261-1269
-
-
Piao, L.1
Zhang, M.2
Datta, J.3
Xie, X.4
Su, T.5
Li, H.6
-
96
-
-
77955022405
-
Development of a lung cancer therapeutic based on the tumor suppressor microrna-34
-
J.F. Wiggins, L. Ruffino, K. Kelnar, M. Omotola, L. Patrawala, and D. Brown Development of a lung cancer therapeutic based on the tumor suppressor microrna-34 Cancer Research 70 2010 5923 5930
-
(2010)
Cancer Research
, vol.70
, pp. 5923-5930
-
-
Wiggins, J.F.1
Ruffino, L.2
Kelnar, K.3
Omotola, M.4
Patrawala, L.5
Brown, D.6
-
97
-
-
79957900919
-
Systemic delivery of tumor suppressor microrna mimics using a neutral lipid emulsion inhibits lung tumors in mice
-
P. Trang, J.F. Wiggins, C.L. Daige, C. Cho, M. Omotola, and D. Brown Systemic delivery of tumor suppressor microrna mimics using a neutral lipid emulsion inhibits lung tumors in mice Molecular Therapy 19 2011 1116 1122
-
(2011)
Molecular Therapy
, vol.19
, pp. 1116-1122
-
-
Trang, P.1
Wiggins, J.F.2
Daige, C.L.3
Cho, C.4
Omotola, M.5
Brown, D.6
-
98
-
-
84863714144
-
Viral delivery of mir-196a ameliorates the sbma phenotype via the silencing of celf2
-
Y. Miyazaki, H. Adachi, M. Katsuno, M. Minamiyama, Y.M. Jiang, and Z. Huang Viral delivery of mir-196a ameliorates the sbma phenotype via the silencing of celf2 Nature Medicine 18 2012 1136 1141
-
(2012)
Nature Medicine
, vol.18
, pp. 1136-1141
-
-
Miyazaki, Y.1
Adachi, H.2
Katsuno, M.3
Minamiyama, M.4
Jiang, Y.M.5
Huang, Z.6
-
99
-
-
44349170706
-
Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
-
DOI 10.1038/mt.2008.76, PII MT200876
-
C. Zincarelli, S. Soltys, G. Rengo, and J.E. Rabinowitz Analysis of aav serotypes 1-9 mediated gene expression and tropism in mice after systemic injection Molecular Therapy 16 2008 1073 1080 (Pubitemid 351737072)
-
(2008)
Molecular Therapy
, vol.16
, Issue.6
, pp. 1073-1080
-
-
Zincarelli, C.1
Soltys, S.2
Rengo, G.3
Rabinowitz, J.E.4
-
101
-
-
84870218649
-
Strategies to deliver micrornas as potential therapeutics in the treatment of cardiovascular pathology
-
D.A. Chistiakov, I.A. Sobenin, and A.N. Orekhov Strategies to deliver micrornas as potential therapeutics in the treatment of cardiovascular pathology Drug Delivery 19 2012 392 405
-
(2012)
Drug Delivery
, vol.19
, pp. 392-405
-
-
Chistiakov, D.A.1
Sobenin, I.A.2
Orekhov, A.N.3
-
102
-
-
79953301730
-
Micrornas are transported in plasma and delivered to recipient cells by high-density lipoproteins
-
K.C. Vickers, B.T. Palmisano, B.M. Shoucri, R.D. Shamburek, and A.T. Remaley Micrornas are transported in plasma and delivered to recipient cells by high-density lipoproteins Nature Cell Biology 13 2011 423 433
-
(2011)
Nature Cell Biology
, vol.13
, pp. 423-433
-
-
Vickers, K.C.1
Palmisano, B.T.2
Shoucri, B.M.3
Shamburek, R.D.4
Remaley, A.T.5
-
103
-
-
79953202200
-
Argonaute2 complexes carry a population of circulating micrornas independent of vesicles in human plasma
-
J.D. Arroyo, J.R. Chevillet, E.M. Kroh, I.K. Ruf, C.C. Pritchard, and D.F. Gibson Argonaute2 complexes carry a population of circulating micrornas independent of vesicles in human plasma Proceedings of the National Academy of Sciences of the United States of America 108 2011 5003 5008
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 5003-5008
-
-
Arroyo, J.D.1
Chevillet, J.R.2
Kroh, E.M.3
Ruf, I.K.4
Pritchard, C.C.5
Gibson, D.F.6
-
104
-
-
84862777377
-
Secreted micrornas: A new form of intercellular communication
-
X. Chen, H. Liang, J. Zhang, K. Zen, and C.Y. Zhang Secreted micrornas: a new form of intercellular communication Trends in Cell Biology 22 2012 125 132
-
(2012)
Trends in Cell Biology
, vol.22
, pp. 125-132
-
-
Chen, X.1
Liang, H.2
Zhang, J.3
Zen, K.4
Zhang, C.Y.5
-
105
-
-
84869219338
-
Mir-34 - A microrna replacement therapy is headed to the clinic
-
A.G. Bader Mir-34 - a microrna replacement therapy is headed to the clinic Frontiers in Genetics 3 2012 120
-
(2012)
Frontiers in Genetics
, vol.3
, pp. 120
-
-
Bader, A.G.1
-
106
-
-
28444469246
-
Silencing of micrornas in vivo with 'antagomirs'
-
J. Krutzfeldt, N. Rajewsky, R. Braich, K.G. Rajeev, T. Tuschl, and M. Manoharan Silencing of micrornas in vivo with 'antagomirs' Nature 438 2005 685 689
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
-
107
-
-
34250679405
-
Specificity, duplex degradation and subcellular localization of antagomirs
-
DOI 10.1093/nar/gkm024
-
J. Krutzfeldt, S. Kuwajima, R. Braich, K.G. Rajeev, J. Pena, and T. Tuschl Specificity, duplex degradation and subcellular localization of antagomirs Nucleic Acids Research 35 2007 2885 2892 (Pubitemid 47073627)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.9
, pp. 2885-2892
-
-
Krutzfeldt, J.1
Kuwajima, S.2
Braich, R.3
Rajeev, K.G.4
Pena, J.5
Tuschl, T.6
Manoharan, M.7
Stoffel, M.8
-
108
-
-
84864199342
-
Structure and nuclease resistance of 2′,4′-constrained 2′-o-methoxyethyl (cmoe) and 2′-o-ethyl (cet) modified dnas
-
P.S. Pallan, C.R. Allerson, A. Berdeja, P.P. Seth, E.E. Swayze, and T.P. Prakash Structure and nuclease resistance of 2′,4′-constrained 2′-o-methoxyethyl (cmoe) and 2′-o-ethyl (cet) modified dnas Chemical Communications (Cambridge) 48 2012 8195 8197
-
(2012)
Chemical Communications (Cambridge)
, vol.48
, pp. 8195-8197
-
-
Pallan, P.S.1
Allerson, C.R.2
Berdeja, A.3
Seth, P.P.4
Swayze, E.E.5
Prakash, T.P.6
-
109
-
-
77949297395
-
Synthesis and biophysical evaluation of 2',4'-constrained 2'o-methoxyethyl and 2',4'-constrained 2'o-ethyl nucleic acid analogues
-
P.P. Seth, G. Vasquez, C.A. Allerson, A. Berdeja, H. Gaus, and G.A. Kinberger Synthesis and biophysical evaluation of 2',4'-constrained 2'o-methoxyethyl and 2',4'-constrained 2'o-ethyl nucleic acid analogues Journal of Organic Chemistry 75 2010 1569 1581
-
(2010)
Journal of Organic Chemistry
, vol.75
, pp. 1569-1581
-
-
Seth, P.P.1
Vasquez, G.2
Allerson, C.A.3
Berdeja, A.4
Gaus, H.5
Kinberger, G.A.6
-
110
-
-
58549109007
-
Potent inhibition of microrna in vivo without degradation
-
S. Davis, S. Propp, S.M. Freier, L.E. Jones, M.J. Serra, and G. Kinberger Potent inhibition of microrna in vivo without degradation Nucleic Acids Research 37 2009 70 77
-
(2009)
Nucleic Acids Research
, vol.37
, pp. 70-77
-
-
Davis, S.1
Propp, S.2
Freier, S.M.3
Jones, L.E.4
Serra, M.J.5
Kinberger, G.6
-
111
-
-
80054971110
-
Inhibition of mir-33a/b in non-human primates raises plasma hdl and lowers vldl triglycerides
-
K.J. Rayner, C.C. Esau, F.N. Hussain, A.L. McDaniel, S.M. Marshall, and J.M. van Gils Inhibition of mir-33a/b in non-human primates raises plasma hdl and lowers vldl triglycerides Nature 478 2011 404 407
-
(2011)
Nature
, vol.478
, pp. 404-407
-
-
Rayner, K.J.1
Esau, C.C.2
Hussain, F.N.3
McDaniel, A.L.4
Marshall, S.M.5
Van Gils, J.M.6
-
112
-
-
0037140761
-
Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids
-
DOI 10.1021/ja012288d
-
M. Petersen, K. Bondensgaard, J. Wengel, and J.P. Jacobsen Locked nucleic acid (lna) recognition of rna: nmr solution structures of lna:Rna hybrids Journal of the American Chemical Society 124 2002 5974 5982 (Pubitemid 34555398)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.21
, pp. 5974-5982
-
-
Petersen, M.1
Bondensgaard, K.2
Wengel, J.3
Peter Jacobsen, J.4
-
113
-
-
77949676231
-
Locked nucleic acids: Promising nucleic acid analogs for therapeutic applications
-
R.N. Veedu, and J. Wengel Locked nucleic acids: promising nucleic acid analogs for therapeutic applications Chemistry and Biodiversity 7 2010 536 542
-
(2010)
Chemistry and Biodiversity
, vol.7
, pp. 536-542
-
-
Veedu, R.N.1
Wengel, J.2
-
114
-
-
6344277190
-
LNA (Locked Nucleic Acid): High-affinity targeting of complementary RNA and DNA
-
B. Vester, and J. Wengel Lna (locked nucleic acid): High-affinity targeting of complementary rna and DNA Biochemistry 43 2004 13233 13241 (Pubitemid 39391124)
-
(2004)
Biochemistry
, vol.43
, Issue.42
, pp. 13233-13241
-
-
Vester, B.1
Wengel, J.2
-
115
-
-
13744250159
-
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
-
DOI 10.1093/nar/gki193
-
J. Elmen, H. Thonberg, K. Ljungberg, M. Frieden, M. Westergaard, and Y. Xu Locked nucleic acid (lna) mediated improvements in sirna stability and functionality Nucleic Acids Research 33 2005 439 447 (Pubitemid 40276964)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.1
, pp. 439-447
-
-
Elmen, J.1
Thonberg, H.2
Ljungberg, K.3
Frieden, M.4
Westergaard, M.5
Xu, Y.6
Wahren, B.7
Liang, Z.8
Orum, H.9
Koch, T.10
Wahlestedt, C.11
-
116
-
-
74249112787
-
Therapeutic silencing of microrna-122 in primates with chronic hepatitis c virus infection
-
R.E. Lanford, E.S. Hildebrandt-Eriksen, A. Petri, R. Persson, M. Lindow, and M.E. Munk Therapeutic silencing of microrna-122 in primates with chronic hepatitis c virus infection Science 327 2010 198 201
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
-
117
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
DOI 10.1038/nature06783, PII NATURE06783
-
J. Elmen, M. Lindow, S. Schutz, M. Lawrence, A. Petri, and S. Obad Lna-mediated microrna silencing in non-human primates Nature 452 2008 896 899 (Pubitemid 351550859)
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjarn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
118
-
-
79953202455
-
Silencing of microrna families by seed-targeting tiny lnas
-
S. Obad, C.O. dos Santos, A. Petri, M. Heidenblad, O. Broom, and C. Ruse Silencing of microrna families by seed-targeting tiny lnas Nature Genetics 43 2011 371 378
-
(2011)
Nature Genetics
, vol.43
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
Heidenblad, M.4
Broom, O.5
Ruse, C.6
-
119
-
-
49949117302
-
Widespread changes in protein synthesis induced by micrornas
-
M. Selbach, B. Schwanhausser, N. Thierfelder, Z. Fang, R. Khanin, and N. Rajewsky Widespread changes in protein synthesis induced by micrornas Nature 455 2008 58 63
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
121
-
-
33846902312
-
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals
-
DOI 10.1093/nar/gkl1071
-
E.E. Swayze, A.M. Siwkowski, E.V. Wancewicz, M.T. Migawa, T.K. Wyrzykiewicz, and G. Hung Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals Nucleic Acids Research 35 2007 687 700 (Pubitemid 46232083)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.2
, pp. 687-700
-
-
Swayze, E.E.1
Siwkowski, A.M.2
Wancewicz, E.V.3
Migawa, M.T.4
Wyrzykiewicz, T.K.5
Hung, G.6
Monia, B.P.7
Bennett, C.F.8
-
123
-
-
77953780835
-
Microrna-33 and the srebp host genes cooperate to control cholesterol homeostasis
-
S.H. Najafi-Shoushtari, F. Kristo, Y. Li, T. Shioda, D.E. Cohen, and R.E. Gerszten Microrna-33 and the srebp host genes cooperate to control cholesterol homeostasis Science 328 2010 1566 1569
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
Kristo, F.2
Li, Y.3
Shioda, T.4
Cohen, D.E.5
Gerszten, R.E.6
-
125
-
-
78049295975
-
Microrna-33 encoded by an intron of sterol regulatory element-binding protein 2 (srebp2) regulates hdl in vivo
-
T. Horie, K. Ono, M. Horiguchi, H. Nishi, T. Nakamura, and K. Nagao Microrna-33 encoded by an intron of sterol regulatory element-binding protein 2 (srebp2) regulates hdl in vivo Proceedings of the National Academy of Sciences of the United States of America 107 2010 17321 17326
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 17321-17326
-
-
Horie, T.1
Ono, K.2
Horiguchi, M.3
Nishi, H.4
Nakamura, T.5
Nagao, K.6
-
126
-
-
79959326172
-
Mir-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
-
A. Davalos, L. Goedeke, P. Smibert, C.M. Ramirez, N.P. Warrier, and U. Andreo Mir-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling Proceedings of the National Academy of Sciences of the United States of America 108 2011 9232 9237
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 9232-9237
-
-
Davalos, A.1
Goedeke, L.2
Smibert, P.3
Ramirez, C.M.4
Warrier, N.P.5
Andreo, U.6
-
127
-
-
77958553499
-
Expression of mir-33 from an srebp2 intron inhibits cholesterol export and fatty acid oxidation
-
I. Gerin, L.A. Clerbaux, O. Haumont, N. Lanthier, A.K. Das, and C.F. Burant Expression of mir-33 from an srebp2 intron inhibits cholesterol export and fatty acid oxidation Journal of Biological Chemistry 285 2010 33652 33661
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 33652-33661
-
-
Gerin, I.1
Clerbaux, L.A.2
Haumont, O.3
Lanthier, N.4
Das, A.K.5
Burant, C.F.6
-
128
-
-
84874393347
-
Microrna-33 deficiency reduces the progression of atherosclerotic plaque in apoe(-/-) mice
-
T. Horie, O. Baba, Y. Kuwabara, Y. Chujo, S. Watanabe, and M. Kinoshita Microrna-33 deficiency reduces the progression of atherosclerotic plaque in apoe(-/-) mice Journal of American Heart Association 1 2012 e003376
-
(2012)
Journal of American Heart Association
, vol.1
, pp. 003376
-
-
Horie, T.1
Baba, O.2
Kuwabara, Y.3
Chujo, Y.4
Watanabe, S.5
Kinoshita, M.6
-
129
-
-
79960015327
-
Antagonism of mir-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
-
K.J. Rayner, F.J. Sheedy, C.C. Esau, F.N. Hussain, R.E. Temel, and S. Parathath Antagonism of mir-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis Journal of Clinical Investigation 121 2011 2921 2931
-
(2011)
Journal of Clinical Investigation
, vol.121
, pp. 2921-2931
-
-
Rayner, K.J.1
Sheedy, F.J.2
Esau, C.C.3
Hussain, F.N.4
Temel, R.E.5
Parathath, S.6
-
130
-
-
77953762756
-
Medicine. Hdl mir-ed down by srebp introns
-
M.S. Brown, J. Ye, and J.L. Goldstein Medicine. Hdl mir-ed down by srebp introns Science 328 2010 1495 1496
-
(2010)
Science
, vol.328
, pp. 1495-1496
-
-
Brown, M.S.1
Ye, J.2
Goldstein, J.L.3
-
131
-
-
84857953621
-
Mir-33 regulates cell proliferation and cell cycle progression
-
D. Cirera-Salinas, M. Pauta, R.M. Allen, A.G. Salerno, C.M. Ramirez, and A. Chamorro-Jorganes Mir-33 regulates cell proliferation and cell cycle progression Cell Cycle 11 2012 922 933
-
(2012)
Cell Cycle
, vol.11
, pp. 922-933
-
-
Cirera-Salinas, D.1
Pauta, M.2
Allen, R.M.3
Salerno, A.G.4
Ramirez, C.M.5
Chamorro-Jorganes, A.6
-
132
-
-
77955736174
-
Mir-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal
-
A. Herrera-Merchan, C. Cerrato, G. Luengo, O. Dominguez, M.A. Piris, and M. Serrano Mir-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal Cell Cycle 9 2010 3277 3285
-
(2010)
Cell Cycle
, vol.9
, pp. 3277-3285
-
-
Herrera-Merchan, A.1
Cerrato, C.2
Luengo, G.3
Dominguez, O.4
Piris, M.A.5
Serrano, M.6
-
133
-
-
79955673018
-
Cholesterol regulation of receptor-interacting protein 140 via microrna-33 in inflammatory cytokine production
-
P.C. Ho, K.C. Chang, Y.S. Chuang, and L.N. Wei Cholesterol regulation of receptor-interacting protein 140 via microrna-33 in inflammatory cytokine production FASEB Journal 25 2011 1758 1766
-
(2011)
FASEB Journal
, vol.25
, pp. 1758-1766
-
-
Ho, P.C.1
Chang, K.C.2
Chuang, Y.S.3
Wei, L.N.4
-
134
-
-
79960459422
-
Cholesterol metabolism in neurons and astrocytes
-
F.W. Pfrieger, and N. Ungerer Cholesterol metabolism in neurons and astrocytes Progress in Lipid Research 50 2011 357 371
-
(2011)
Progress in Lipid Research
, vol.50
, pp. 357-371
-
-
Pfrieger, F.W.1
Ungerer, N.2
-
135
-
-
4644361588
-
ABCA1 is required for normal central nervous system apoE levels and for lipidation of astrocyte-secreted apoE
-
DOI 10.1074/jbc.M407963200
-
S.E. Wahrle, H. Jiang, M. Parsadanian, J. Legleiter, X. Han, and J.D. Fryer Abca1 is required for normal central nervous system apoe levels and for lipidation of astrocyte-secreted apoe Journal of Biological Chemistry 279 2004 40987 40993 (Pubitemid 39287699)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.39
, pp. 40987-40993
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Legleiter, J.4
Han, X.5
Fryer, J.D.6
Kowalewski, T.7
Holtzman, D.M.8
-
136
-
-
38049098102
-
-
Abcg1 and abcg4 are coexpressed in neurons and astrocytes of the cns and regulate cholesterol homeostasis through srebp-2
-
P.T. Tarr, P.A. Edwards, and Abcg1 and abcg4 are coexpressed in neurons and astrocytes of the cns and regulate cholesterol homeostasis through srebp-2 Journal of Lipid Research 49 2008 169 182
-
(2008)
Journal of Lipid Research
, vol.49
, pp. 169-182
-
-
Tarr, P.T.1
Edwards, P.A.2
-
137
-
-
37549037886
-
Liver x receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the npc1 mouse
-
J.J. Repa, H. Li, T.C. Frank-Cannon, M.A. Valasek, S.D. Turley, and M.G. Tansey Liver x receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the npc1 mouse Journal of Neuroscience 27 2007 14470 14480
-
(2007)
Journal of Neuroscience
, vol.27
, pp. 14470-14480
-
-
Repa, J.J.1
Li, H.2
Frank-Cannon, T.C.3
Valasek, M.A.4
Turley, S.D.5
Tansey, M.G.6
-
138
-
-
80054900644
-
Microrna-758 regulates cholesterol efflux through posttranscriptional repression of atp-binding cassette transporter a1
-
C.M. Ramirez, A. Davalos, L. Goedeke, A.G. Salerno, N. Warrier, and D. Cirera-Salinas Microrna-758 regulates cholesterol efflux through posttranscriptional repression of atp-binding cassette transporter a1 Arteriosclerosis, Thrombosis, and Vascular Biology 31 2011 2707 2714
-
(2011)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.31
, pp. 2707-2714
-
-
Ramirez, C.M.1
Davalos, A.2
Goedeke, L.3
Salerno, A.G.4
Warrier, N.5
Cirera-Salinas, D.6
-
139
-
-
84860377430
-
Mir-106b impairs cholesterol efflux and increases abeta levels by repressing abca1 expression
-
J. Kim, H. Yoon, C.M. Ramirez, S.M. Lee, H.S. Hoe, and C. Fernandez-Hernando Mir-106b impairs cholesterol efflux and increases abeta levels by repressing abca1 expression Experimental Neurology 235 2012 476 483
-
(2012)
Experimental Neurology
, vol.235
, pp. 476-483
-
-
Kim, J.1
Yoon, H.2
Ramirez, C.M.3
Lee, S.M.4
Hoe, H.S.5
Fernandez-Hernando, C.6
-
141
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
DOI 10.1073/pnas.95.11.6460
-
M. Simons, P. Keller, B. De Strooper, K. Beyreuther, C.G. Dotti, and K. Simons Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons Proceedings of the National Academy of Sciences of the United States of America 95 1998 6460 6464 (Pubitemid 28249035)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
142
-
-
79959569726
-
The microrna cluster mir-106b∼25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation
-
J.O. Brett, V.M. Renault, V.A. Rafalski, A.E. Webb, and A. Brunet The microrna cluster mir-106b∼25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation Aging (Albany NY) 3 2011 108 124
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 108-124
-
-
Brett, J.O.1
Renault, V.M.2
Rafalski, V.A.3
Webb, A.E.4
Brunet, A.5
-
143
-
-
61349110680
-
Microrna regulation of alzheimer's amyloid precursor protein expression
-
S.S. Hebert, K. Horre, L. Nicolai, B. Bergmans, A.S. Papadopoulou, and A. Delacourte Microrna regulation of alzheimer's amyloid precursor protein expression Neurobiology of Disease 33 2009 422 428
-
(2009)
Neurobiology of Disease
, vol.33
, pp. 422-428
-
-
Hebert, S.S.1
Horre, K.2
Nicolai, L.3
Bergmans, B.4
Papadopoulou, A.S.5
Delacourte, A.6
-
144
-
-
84861183215
-
Mir-26 controls lxr-dependent cholesterol efflux by targeting abca1 and arl7
-
D. Sun, J. Zhang, J. Xie, W. Wei, M. Chen, and X. Zhao Mir-26 controls lxr-dependent cholesterol efflux by targeting abca1 and arl7 FEBS Letters 586 2012 1472 1479
-
(2012)
FEBS Letters
, vol.586
, pp. 1472-1479
-
-
Sun, D.1
Zhang, J.2
Xie, J.3
Wei, W.4
Chen, M.5
Zhao, X.6
-
145
-
-
2442498522
-
ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export
-
DOI 10.1016/j.febslet.2004.04.048, PII S0014579304005162
-
T. Engel, A. Lueken, G. Bode, U. Hobohm, S. Lorkowski, and B. Schlueter Adp-ribosylation factor (arf)-like 7 (arl7) is induced by cholesterol loading and participates in apolipoprotein ai-dependent cholesterol export FEBS Letters 566 2004 241 246 (Pubitemid 38625965)
-
(2004)
FEBS Letters
, vol.566
, Issue.1-3
, pp. 241-246
-
-
Engel, T.1
Lueken, A.2
Bode, G.3
Hobohm, U.4
Lorkowski, S.5
Schlueter, B.6
Rust, S.7
Cullen, P.8
Pech, M.9
Assmann, G.10
Seedorf, U.11
-
146
-
-
79953737607
-
Microrna hsa-mir-613 targets the human lxralpha gene and mediates a feedback loop of lxralpha autoregulation
-
Z. Ou, T. Wada, R. Gramignoli, S. Li, S.C. Strom, and M. Huang Microrna hsa-mir-613 targets the human lxralpha gene and mediates a feedback loop of lxralpha autoregulation Molecular Endocrinology 25 2011 584 596
-
(2011)
Molecular Endocrinology
, vol.25
, pp. 584-596
-
-
Ou, Z.1
Wada, T.2
Gramignoli, R.3
Li, S.4
Strom, S.C.5
Huang, M.6
-
147
-
-
84862276328
-
Structure, function and diversity of the healthy human microbiome
-
Anon Structure, function and diversity of the healthy human microbiome Nature 486 2012 207 214
-
(2012)
Nature
, vol.486
, pp. 207-214
-
-
-
148
-
-
84866168894
-
Functional interactions between the gut microbiota and host metabolism
-
V. Tremaroli, and F. Backhed Functional interactions between the gut microbiota and host metabolism Nature 489 2012 242 249
-
(2012)
Nature
, vol.489
, pp. 242-249
-
-
Tremaroli, V.1
Backhed, F.2
-
150
-
-
80051791999
-
Cyanidin-3-o-beta-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein e-deficient mice
-
D. Wang, T. Zou, Y. Yang, X. Yan, and W. Ling Cyanidin-3-o-beta-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein e-deficient mice Biochemical Pharmacology 82 2011 713 719
-
(2011)
Biochemical Pharmacology
, vol.82
, pp. 713-719
-
-
Wang, D.1
Zou, T.2
Yang, Y.3
Yan, X.4
Ling, W.5
-
151
-
-
79952774089
-
Metabolic fate of polyphenols in the human superorganism
-
J. van Duynhoven, E.E. Vaughan, D.M. Jacobs, R.A. Kemperman, E.J. van Velzen, and G. Gross Metabolic fate of polyphenols in the human superorganism Proceedings of the National Academy of Sciences of the United States of America 108 Suppl 1 2011 4531 4538
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.SUPPL. 1
, pp. 4531-4538
-
-
Van Duynhoven, J.1
Vaughan, E.E.2
Jacobs, D.M.3
Kemperman, R.A.4
Van Velzen, E.J.5
Gross, G.6
-
152
-
-
78650338831
-
Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein e-deficient mice
-
D. Wang, X. Wei, X. Yan, T. Jin, and W. Ling Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein e-deficient mice Journal of Agricultural and Food Chemistry 58 2010 12722 12728
-
(2010)
Journal of Agricultural and Food Chemistry
, vol.58
, pp. 12722-12728
-
-
Wang, D.1
Wei, X.2
Yan, X.3
Jin, T.4
Ling, W.5
-
153
-
-
84866973849
-
Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing mirna-10b
-
D. Wang, M. Xia, X. Yan, D. Li, L. Wang, and Y. Xu Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing mirna-10b Circulation Research 111 2012 967 981
-
(2012)
Circulation Research
, vol.111
, pp. 967-981
-
-
Wang, D.1
Xia, M.2
Yan, X.3
Li, D.4
Wang, L.5
Xu, Y.6
-
154
-
-
84868246872
-
Mir-10b downregulates the stress-induced cell surface molecule micb, a critical ligand for cancer cell recognition by natural killer cells
-
P. Tsukerman, N. Stern-Ginossar, C. Gur, A. Glasner, D. Nachmani, and Y. Bauman Mir-10b downregulates the stress-induced cell surface molecule micb, a critical ligand for cancer cell recognition by natural killer cells Cancer Research 72 2012 5463 5472
-
(2012)
Cancer Research
, vol.72
, pp. 5463-5472
-
-
Tsukerman, P.1
Stern-Ginossar, N.2
Gur, C.3
Glasner, A.4
Nachmani, D.5
Bauman, Y.6
-
155
-
-
80655134727
-
Context effect: Microrna-10b in cancer cell proliferation, spread and death
-
G. Gabriely, N.M. Teplyuk, and A.M. Krichevsky Context effect: microrna-10b in cancer cell proliferation, spread and death Autophagy 7 2011 1384 1386
-
(2011)
Autophagy
, vol.7
, pp. 1384-1386
-
-
Gabriely, G.1
Teplyuk, N.M.2
Krichevsky, A.M.3
-
156
-
-
77956290858
-
Resveratrol decreases the levels of mir-155 by upregulating mir-663, a microrna targeting junb and jund
-
E. Tili, J.J. Michaille, B. Adair, H. Alder, E. Limagne, and C. Taccioli Resveratrol decreases the levels of mir-155 by upregulating mir-663, a microrna targeting junb and jund Carcinogenesis 31 2010 1561 1566
-
(2010)
Carcinogenesis
, vol.31
, pp. 1561-1566
-
-
Tili, E.1
Michaille, J.J.2
Adair, B.3
Alder, H.4
Limagne, E.5
Taccioli, C.6
-
157
-
-
79955753386
-
Microbiota modulate host gene expression via micrornas
-
G. Dalmasso, H.T. Nguyen, Y. Yan, H. Laroui, M.A. Charania, and S. Ayyadurai Microbiota modulate host gene expression via micrornas PLoS One 6 2011 e19293
-
(2011)
PLoS One
, vol.6
, pp. 19293
-
-
Dalmasso, G.1
Nguyen, H.T.2
Yan, Y.3
Laroui, H.4
Charania, M.A.5
Ayyadurai, S.6
-
158
-
-
82955214628
-
Polyphenols and cardiovascular disease: A critical summary of the evidence
-
F. Visioli, and A. Davalos Polyphenols and cardiovascular disease: a critical summary of the evidence Mini Reviews in Medicinal Chemistry 11 2011 1186 1190
-
(2011)
Mini Reviews in Medicinal Chemistry
, vol.11
, pp. 1186-1190
-
-
Visioli, F.1
Davalos, A.2
-
159
-
-
84864872512
-
Micrornas in autophagy and their emerging roles in crosstalk with apoptosis
-
J. Xu, Y. Wang, X. Tan, and H. Jing Micrornas in autophagy and their emerging roles in crosstalk with apoptosis Autophagy 8 2012 873 882
-
(2012)
Autophagy
, vol.8
, pp. 873-882
-
-
Xu, J.1
Wang, Y.2
Tan, X.3
Jing, H.4
-
160
-
-
80054845679
-
Interaction abolishment between mutant caveolin-1(delta62-100) and abca1 reduces hdl-mediated cellular cholesterol efflux
-
C.Y. Kuo, Y.C. Lin, J.J. Yang, and V.C. Yang Interaction abolishment between mutant caveolin-1(delta62-100) and abca1 reduces hdl-mediated cellular cholesterol efflux Biochemical and Biophysical Research Communications 414 2011 337 343
-
(2011)
Biochemical and Biophysical Research Communications
, vol.414
, pp. 337-343
-
-
Kuo, C.Y.1
Lin, Y.C.2
Yang, J.J.3
Yang, V.C.4
-
161
-
-
79959845414
-
Stoffel M. Micrornas 103 and 107 regulate insulin sensitivity
-
M. Trajkovski, J. Hausser, J. Soutschek, B. Bhat, A. Akin, and M. Zavolan
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
Hausser, J.2
Soutschek, J.3
Bhat, B.4
Akin, A.5
Zavolan, M.6
-
162
-
-
78650825062
-
Caveolin-1 mediates tumor cell migration and invasion and its regulation by mir-133a in head and neck squamous cell carcinoma
-
N. Nohata, T. Hanazawa, N. Kikkawa, M. Mutallip, L. Fujimura, and H. Yoshino Caveolin-1 mediates tumor cell migration and invasion and its regulation by mir-133a in head and neck squamous cell carcinoma International Journal of Oncology 38 2011 209 217
-
(2011)
International Journal of Oncology
, vol.38
, pp. 209-217
-
-
Nohata, N.1
Hanazawa, T.2
Kikkawa, N.3
Mutallip, M.4
Fujimura, L.5
Yoshino, H.6
-
163
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
C.D. Mathers, and D. Loncar Projections of global mortality and burden of disease from 2002 to 2030 PLoS Med 3 2006 e442
-
(2006)
PLoS Med
, vol.3
, pp. 442
-
-
Mathers, C.D.1
Loncar, D.2
|