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Volumn 300, Issue , 2012, Pages 277-291

Cargo distributions differentiate pathological axonal transport impairments

Author keywords

G93A SOD1 model; Molecular motor; Motoneuron disease; Neurofilament; Transgenic mouse

Indexed keywords

AXONEMAL DYNEIN; COPPER ZINC SUPEROXIDE DISMUTASE; KINESIN; MOLECULAR MOTOR;

EID: 84856997490     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2012.01.019     Document Type: Article
Times cited : (14)

References (66)
  • 1
    • 0034631964 scopus 로고    scopus 로고
    • Glutamate slows axonal transport of neurofilaments in transfected neurons
    • Ackerley S., et al. Glutamate slows axonal transport of neurofilaments in transfected neurons. J. Cell Biol. 2000, 150(1):165-176.
    • (2000) J. Cell Biol. , vol.150 , Issue.1 , pp. 165-176
    • Ackerley, S.1
  • 2
    • 0038612845 scopus 로고    scopus 로고
    • Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments
    • Ackerley S., et al. Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments. J. Cell Biol. 2003, 161(3):489-495.
    • (2003) J. Cell Biol. , vol.161 , Issue.3 , pp. 489-495
    • Ackerley, S.1
  • 3
    • 33846224191 scopus 로고    scopus 로고
    • Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations
    • Baloh R.H., et al. Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. J. Neurosci. 2007, 27(2):422-430.
    • (2007) J. Neurosci. , vol.27 , Issue.2 , pp. 422-430
    • Baloh, R.H.1
  • 5
    • 38749141397 scopus 로고    scopus 로고
    • Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides
    • Barkus R.V., et al. Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Mol. Biol. Cell 2008, 19(1):274-283.
    • (2008) Mol. Biol. Cell , vol.19 , Issue.1 , pp. 274-283
    • Barkus, R.V.1
  • 6
    • 78650545423 scopus 로고    scopus 로고
    • Deficits in axonal transport precede ALS symptoms in vivo
    • Bilsland L.G., et al. Deficits in axonal transport precede ALS symptoms in vivo. Proc. Natl. Acad. Sci. U S A 2010, 107(47):20523-20528.
    • (2010) Proc. Natl. Acad. Sci. U S A , vol.107 , Issue.47 , pp. 20523-20528
    • Bilsland, L.G.1
  • 7
    • 0021808444 scopus 로고
    • A novel brain ATPase with properties expected for the fast axonal transport motor
    • Brady S.T. A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 1985, 317(6032):73-75.
    • (1985) Nature , vol.317 , Issue.6032 , pp. 73-75
    • Brady, S.T.1
  • 8
    • 24344435089 scopus 로고    scopus 로고
    • Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis
    • Brown A., et al. Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis. Mol. Biol. Cell 2005, 16(9):4243-4255.
    • (2005) Mol. Biol. Cell , vol.16 , Issue.9 , pp. 4243-4255
    • Brown, A.1
  • 9
    • 0036849511 scopus 로고    scopus 로고
    • Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
    • Brownlees J., et al. Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport. Hum. Mol. Genet. 2002, 11(23):2837-2844.
    • (2002) Hum. Mol. Genet. , vol.11 , Issue.23 , pp. 2837-2844
    • Brownlees, J.1
  • 10
    • 79955479720 scopus 로고    scopus 로고
    • Regulation of axonal mitochondrial transport and its impact on synaptic transmission
    • Cai Q., et al. Regulation of axonal mitochondrial transport and its impact on synaptic transmission. Neurosci. Res. 2011, 70(1):9-15.
    • (2011) Neurosci. Res. , vol.70 , Issue.1 , pp. 9-15
    • Cai, Q.1
  • 11
    • 26944440868 scopus 로고    scopus 로고
    • A dynamical system model of neurofilament transport in axons
    • Craciun G., et al. A dynamical system model of neurofilament transport in axons. J. Theor. Biol. 2005, 237(3):316-322.
    • (2005) J. Theor. Biol. , vol.237 , Issue.3 , pp. 316-322
    • Craciun, G.1
  • 12
    • 35548991459 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
    • De Vos K.J., et al. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum. Mol. Genet. 2007, 16(22):2720-2728.
    • (2007) Hum. Mol. Genet. , vol.16 , Issue.22 , pp. 2720-2728
    • De Vos, K.J.1
  • 13
    • 48249102303 scopus 로고    scopus 로고
    • Role of axonal transport in neurodegenerative diseases
    • De Vos K.J., et al. Role of axonal transport in neurodegenerative diseases. Annu. Rev. Neurosci. 2008, 31:151-173.
    • (2008) Annu. Rev. Neurosci. , vol.31 , pp. 151-173
    • De Vos, K.J.1
  • 14
    • 0038442784 scopus 로고    scopus 로고
    • Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS
    • Elam J.S., et al. Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS. Nat. Struct. Biol. 2003, 10(6):461-467.
    • (2003) Nat. Struct. Biol. , vol.10 , Issue.6 , pp. 461-467
    • Elam, J.S.1
  • 15
    • 0037221596 scopus 로고    scopus 로고
    • Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis
    • Ellis D.Z., et al. Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci. 2003, 23(1):43-51.
    • (2003) J. Neurosci. , vol.23 , Issue.1 , pp. 43-51
    • Ellis, D.Z.1
  • 16
    • 79958149265 scopus 로고    scopus 로고
    • How molecular motors are arranged on a cargo is important for vesicular transport
    • Erickson R.P., et al. How molecular motors are arranged on a cargo is important for vesicular transport. PLoS Comput. Biol. 2011, 7(5):e1002032.
    • (2011) PLoS Comput. Biol. , vol.7 , Issue.5
    • Erickson, R.P.1
  • 17
    • 0141862030 scopus 로고    scopus 로고
    • Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases
    • Feany M.B., La Spada A.R. Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases. Neuron 2003, 40(1):1-2.
    • (2003) Neuron , vol.40 , Issue.1 , pp. 1-2
    • Feany, M.B.1    La Spada, A.R.2
  • 18
    • 79955097181 scopus 로고    scopus 로고
    • A mutation in the dynein heavy chain gene compensates for energy deficit of mutant SOD1 mice and increases potentially neuroprotective IGF-1
    • Fergani A., et al. A mutation in the dynein heavy chain gene compensates for energy deficit of mutant SOD1 mice and increases potentially neuroprotective IGF-1. Mol. Neurodegener. 2011, 6(1):26.
    • (2011) Mol. Neurodegener. , vol.6 , Issue.1 , pp. 26
    • Fergani, A.1
  • 19
    • 1342310772 scopus 로고    scopus 로고
    • Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport
    • Ferreirinha F., et al. Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J. Clin. Invest. 2004, 113(2):231-242.
    • (2004) J. Clin. Invest. , vol.113 , Issue.2 , pp. 231-242
    • Ferreirinha, F.1
  • 20
    • 33646171262 scopus 로고    scopus 로고
    • A simple theoretical model explains dynein's response to load
    • Gao Y.Q. A simple theoretical model explains dynein's response to load. Biophys. J. 2006, 90(3):811-821.
    • (2006) Biophys. J. , vol.90 , Issue.3 , pp. 811-821
    • Gao, Y.Q.1
  • 21
    • 74549183460 scopus 로고    scopus 로고
    • A stochastic model for microtubule motors describes the in vivo cytoplasmic transport of human adenovirus
    • Gazzola M., et al. A stochastic model for microtubule motors describes the in vivo cytoplasmic transport of human adenovirus. PLoS Comput. Biol. 2009, 5(12):e1000623.
    • (2009) PLoS Comput. Biol. , vol.5 , Issue.12
    • Gazzola, M.1
  • 22
    • 0035829720 scopus 로고    scopus 로고
    • Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
    • Gunawardena S., Goldstein L.S. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 2001, 32(3):389-401.
    • (2001) Neuron , vol.32 , Issue.3 , pp. 389-401
    • Gunawardena, S.1    Goldstein, L.S.2
  • 23
    • 33645225597 scopus 로고    scopus 로고
    • Pathogenic superoxide dismutase structure, folding, aggregation and turnover
    • Hart P.J. Pathogenic superoxide dismutase structure, folding, aggregation and turnover. Curr. Opin. Chem. Biol. 2006, 10(2):131-138.
    • (2006) Curr. Opin. Chem. Biol. , vol.10 , Issue.2 , pp. 131-138
    • Hart, P.J.1
  • 24
    • 57349172663 scopus 로고    scopus 로고
    • Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
    • Ittner L.M., et al. Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proc. Natl. Acad. Sci U S A 2008, 105(41):15997-16002.
    • (2008) Proc. Natl. Acad. Sci U S A , vol.105 , Issue.41 , pp. 15997-16002
    • Ittner, L.M.1
  • 25
    • 19944432585 scopus 로고    scopus 로고
    • Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
    • Jiang Y.M., et al. Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann. Neurol. 2005, 57(2):236-251.
    • (2005) Ann. Neurol. , vol.57 , Issue.2 , pp. 236-251
    • Jiang, Y.M.1
  • 27
    • 70049086023 scopus 로고    scopus 로고
    • Can molecular motors drive distance measurements in injured neurons?
    • Kam N., et al. Can molecular motors drive distance measurements in injured neurons?. PLoS Comput. Biol. 2009, 5(8):e1000477.
    • (2009) PLoS Comput. Biol. , vol.5 , Issue.8
    • Kam, N.1
  • 28
    • 67449132352 scopus 로고    scopus 로고
    • Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients
    • Kasher P.R., et al. Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients. J. Neurochem. 2009, 110(1):34-44.
    • (2009) J. Neurochem. , vol.110 , Issue.1 , pp. 34-44
    • Kasher, P.R.1
  • 29
    • 21344472483 scopus 로고    scopus 로고
    • A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice
    • Kieran D., et al. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J. Cell Biol. 2005, 169(4):561-567.
    • (2005) J. Cell Biol. , vol.169 , Issue.4 , pp. 561-567
    • Kieran, D.1
  • 30
    • 79955481136 scopus 로고    scopus 로고
    • Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI
    • Kim J., et al. Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI. Neuroimage 2011, 56(3):1286-1292.
    • (2011) Neuroimage , vol.56 , Issue.3 , pp. 1286-1292
    • Kim, J.1
  • 31
    • 28444447392 scopus 로고    scopus 로고
    • Cooperative cargo transport by several molecular motors
    • Klumpp S., Lipowsky R. Cooperative cargo transport by several molecular motors. Proc. Natl. Acad. Sci. U S A 2005, 102(48):17284-17289.
    • (2005) Proc. Natl. Acad. Sci. U S A , vol.102 , Issue.48 , pp. 17284-17289
    • Klumpp, S.1    Lipowsky, R.2
  • 32
    • 20344382542 scopus 로고    scopus 로고
    • Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement?
    • Kural C., et al. Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement?. Science 2005, 308(5727):1469-1472.
    • (2005) Science , vol.308 , Issue.5727 , pp. 1469-1472
    • Kural, C.1
  • 33
    • 77954143232 scopus 로고    scopus 로고
    • Effect of vesicle traps on traffic jam formation in fast axonal transport
    • Kuznetsov A.V. Effect of vesicle traps on traffic jam formation in fast axonal transport. Math. Biosci. 2010, 226(2):147-155.
    • (2010) Math. Biosci. , vol.226 , Issue.2 , pp. 147-155
    • Kuznetsov, A.V.1
  • 34
    • 0037198698 scopus 로고    scopus 로고
    • Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration
    • LaMonte B.H., et al. Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron 2002, 34(5):715-727.
    • (2002) Neuron , vol.34 , Issue.5 , pp. 715-727
    • LaMonte, B.H.1
  • 35
    • 62849088641 scopus 로고    scopus 로고
    • The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity
    • LaPointe N.E., et al. The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. J. Neurosci. Res. 2009, 87(2):440-451.
    • (2009) J. Neurosci. Res. , vol.87 , Issue.2 , pp. 440-451
    • LaPointe, N.E.1
  • 36
    • 1542267796 scopus 로고    scopus 로고
    • Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease
    • Lee W.C., et al. Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease. Proc. Natl. Acad. Sci. U S A 2004, 101(9):3224-3229.
    • (2004) Proc. Natl. Acad. Sci. U S A , vol.101 , Issue.9 , pp. 3224-3229
    • Lee, W.C.1
  • 37
    • 66749104344 scopus 로고    scopus 로고
    • Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis
    • Magrane J., Manfredi G. Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis. Antioxid. Redox Signal. 2009, 11(7):1615-1626.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.7 , pp. 1615-1626
    • Magrane, J.1    Manfredi, G.2
  • 38
    • 0032741064 scopus 로고    scopus 로고
    • Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
    • Martin M., et al. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol. Biol. Cell 1999, 10(11):3717-3728.
    • (1999) Mol. Biol. Cell , vol.10 , Issue.11 , pp. 3717-3728
    • Martin, M.1
  • 39
    • 0036179612 scopus 로고    scopus 로고
    • Axonal transport of neurofilaments in normal and disease states
    • Miller C.C., et al. Axonal transport of neurofilaments in normal and disease states. Cell Mol. Life Sci. 2002, 59(2):323-330.
    • (2002) Cell Mol. Life Sci. , vol.59 , Issue.2 , pp. 323-330
    • Miller, C.C.1
  • 40
    • 77949801029 scopus 로고    scopus 로고
    • Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
    • Misko A., et al. Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J. Neurosci. 2010, 30(12):4232-4240.
    • (2010) J. Neurosci. , vol.30 , Issue.12 , pp. 4232-4240
    • Misko, A.1
  • 41
    • 36949025998 scopus 로고    scopus 로고
    • An analysis of glutamate spillover on the N-methyl-d-aspartate receptors at the cerebellar glomerulus
    • Mitchell C.S., et al. An analysis of glutamate spillover on the N-methyl-d-aspartate receptors at the cerebellar glomerulus. J. Neural Eng. 2007, 4(3):276-282.
    • (2007) J. Neural Eng. , vol.4 , Issue.3 , pp. 276-282
    • Mitchell, C.S.1
  • 42
    • 36949035996 scopus 로고    scopus 로고
    • Output-based comparison of alternative kinetic schemes for the NMDA receptor within a glutamate spillover model
    • Mitchell C.S., Lee R.H. Output-based comparison of alternative kinetic schemes for the NMDA receptor within a glutamate spillover model. J. Neural Eng. 2007, 4(4):380-389.
    • (2007) J. Neural Eng. , vol.4 , Issue.4 , pp. 380-389
    • Mitchell, C.S.1    Lee, R.H.2
  • 43
    • 59649093550 scopus 로고    scopus 로고
    • Pathology dynamics predict spinal cord injury therapeutic success
    • Mitchell C.S., Lee R.H. Pathology dynamics predict spinal cord injury therapeutic success. J. Neurotrauma 2008, 25(12):1483-1497.
    • (2008) J. Neurotrauma , vol.25 , Issue.12 , pp. 1483-1497
    • Mitchell, C.S.1    Lee, R.H.2
  • 44
    • 61449162912 scopus 로고    scopus 로고
    • A quantitative examination of the role of cargo-exerted forces in axonal transport
    • Mitchell C.S., Lee R.H. A quantitative examination of the role of cargo-exerted forces in axonal transport. J. Theor. Biol. 2009, 257(3):430-437.
    • (2009) J. Theor. Biol. , vol.257 , Issue.3 , pp. 430-437
    • Mitchell, C.S.1    Lee, R.H.2
  • 45
    • 84858287016 scopus 로고    scopus 로고
    • Dynamic meta-analysis as a therapeutic prediction tool for amyotrophic lateral sclerosis
    • InTech
    • Mitchell C.S., Lee R.H. Dynamic meta-analysis as a therapeutic prediction tool for amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis 2012, InTech.
    • (2012) Amyotrophic Lateral Sclerosis
    • Mitchell, C.S.1    Lee, R.H.2
  • 46
    • 0036043950 scopus 로고    scopus 로고
    • Fast axonal transport misregulation and Alzheimer's disease
    • Morfini G., et al. Fast axonal transport misregulation and Alzheimer's disease. Neuromolecular Med. 2002, 2(2):89-99.
    • (2002) Neuromolecular Med. , vol.2 , Issue.2 , pp. 89-99
    • Morfini, G.1
  • 47
    • 70350455072 scopus 로고    scopus 로고
    • Axonal transport defects in neurodegenerative diseases
    • Morfini G.A., et al. Axonal transport defects in neurodegenerative diseases. J. Neurosci. 2009, 29(41):12776-12786.
    • (2009) J. Neurosci. , vol.29 , Issue.41 , pp. 12776-12786
    • Morfini, G.A.1
  • 48
    • 67649826155 scopus 로고    scopus 로고
    • Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
    • Morfini G.A., et al. Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nat. Neurosci. 2009, 12(7):864-871.
    • (2009) Nat. Neurosci. , vol.12 , Issue.7 , pp. 864-871
    • Morfini, G.A.1
  • 49
    • 42449124179 scopus 로고    scopus 로고
    • Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
    • Muller M.J., et al. Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors. Proc. Natl. Acad. Sci. U S A 2008, 105(12):4609-4614.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , Issue.12 , pp. 4609-4614
    • Muller, M.J.1
  • 50
    • 34248512129 scopus 로고    scopus 로고
    • Differential expression of molecular motors in the motor cortex of sporadic ALS
    • Pantelidou M., et al. Differential expression of molecular motors in the motor cortex of sporadic ALS. Neurobiol. Dis. 2007, 26(3):577-589.
    • (2007) Neurobiol. Dis. , vol.26 , Issue.3 , pp. 577-589
    • Pantelidou, M.1
  • 51
    • 11144353869 scopus 로고    scopus 로고
    • Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons
    • Saha A.R., et al. Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons. J. Cell Sci. 2004, 117(Pt 7):1017-1024.
    • (2004) J. Cell Sci. , vol.117 , Issue.PART. 7 , pp. 1017-1024
    • Saha, A.R.1
  • 52
    • 2342418195 scopus 로고    scopus 로고
    • Slow component of axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene
    • Sasaki S., et al. Slow component of axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene. Acta Neuropathol. 2004, 107(5):452-460.
    • (2004) Acta Neuropathol. , vol.107 , Issue.5 , pp. 452-460
    • Sasaki, S.1
  • 53
    • 23644437653 scopus 로고    scopus 로고
    • Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
    • Sasaki S., et al. Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene. Acta Neuropathol. 2005, 110(1):48-56.
    • (2005) Acta Neuropathol. , vol.110 , Issue.1 , pp. 48-56
    • Sasaki, S.1
  • 54
    • 78651499280 scopus 로고    scopus 로고
    • Dysregulation of axonal transport and motorneuron diseases
    • Sau D., et al. Dysregulation of axonal transport and motorneuron diseases. Biol. Cell 2011, 103(2):87-107.
    • (2011) Biol. Cell , vol.103 , Issue.2 , pp. 87-107
    • Sau, D.1
  • 55
    • 34447560063 scopus 로고    scopus 로고
    • Synaptic amplification versus bistability in motoneuron dendritic processing: a top-down modeling approach
    • Shapiro N.P., Lee R.H. Synaptic amplification versus bistability in motoneuron dendritic processing: a top-down modeling approach. J. Neurophysiol. 2007, 97(6):3948-3960.
    • (2007) J. Neurophysiol. , vol.97 , Issue.6 , pp. 3948-3960
    • Shapiro, N.P.1    Lee, R.H.2
  • 56
    • 77954957020 scopus 로고    scopus 로고
    • Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport
    • Shi P., et al. Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport. Biochim. Biophys. Acta 2010, 1802(9):707-716.
    • (2010) Biochim. Biophys. Acta , vol.1802 , Issue.9 , pp. 707-716
    • Shi, P.1
  • 57
    • 64449085303 scopus 로고    scopus 로고
    • Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons
    • Sinadinos C., et al. Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons. Neurobiol. Dis. 2009, 34(2):389-395.
    • (2009) Neurobiol. Dis. , vol.34 , Issue.2 , pp. 389-395
    • Sinadinos, C.1
  • 58
    • 50849083264 scopus 로고    scopus 로고
    • Retrograde axonal transport and motor neuron disease
    • Strom A.L., et al. Retrograde axonal transport and motor neuron disease. J. Neurochem. 2008, 106(2):495-505.
    • (2008) J. Neurochem. , vol.106 , Issue.2 , pp. 495-505
    • Strom, A.L.1
  • 59
    • 60549104791 scopus 로고    scopus 로고
    • Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3
    • Tateno M., et al. Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. Hum. Mol. Genet. 2009, 18(5):942-955.
    • (2009) Hum. Mol. Genet. , vol.18 , Issue.5 , pp. 942-955
    • Tateno, M.1
  • 60
    • 32644433034 scopus 로고    scopus 로고
    • A dynein mutation attenuates motor neuron degeneration in SOD1(G93A) mice
    • Teuchert M., et al. A dynein mutation attenuates motor neuron degeneration in SOD1(G93A) mice. Exp. Neurol. 2006, 198(1):271-274.
    • (2006) Exp. Neurol. , vol.198 , Issue.1 , pp. 271-274
    • Teuchert, M.1
  • 61
    • 0035166607 scopus 로고    scopus 로고
    • Rapid intermittent movement of axonal neurofilaments observed by fluorescence photobleaching
    • Wang L., Brown A. Rapid intermittent movement of axonal neurofilaments observed by fluorescence photobleaching. Mol. Biol. Cell 2001, 12(10):3257-3267.
    • (2001) Mol. Biol. Cell , vol.12 , Issue.10 , pp. 3257-3267
    • Wang, L.1    Brown, A.2
  • 62
    • 76549123596 scopus 로고    scopus 로고
    • Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons
    • Wang X., et al. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener. Dis. 2010, 7(1-3):56-59.
    • (2010) Neurodegener. Dis. , vol.7 , Issue.1-3 , pp. 56-59
    • Wang, X.1
  • 63
    • 0033585832 scopus 로고    scopus 로고
    • Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene
    • Warita H., et al. Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene. Brain Res. 1999, 819(1-2):120-131.
    • (1999) Brain Res. , vol.819 , Issue.1-2 , pp. 120-131
    • Warita, H.1
  • 64
    • 0033366384 scopus 로고    scopus 로고
    • Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
    • Williamson T.L., Cleveland D.W. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci. 1999, 2(1):50-56.
    • (1999) Nat. Neurosci. , vol.2 , Issue.1 , pp. 50-56
    • Williamson, T.L.1    Cleveland, D.W.2
  • 65
    • 0037437149 scopus 로고    scopus 로고
    • Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A
    • Xia C.H., et al. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J. Cell Biol. 2003, 161(1):55-66.
    • (2003) J. Cell Biol. , vol.161 , Issue.1 , pp. 55-66
    • Xia, C.H.1
  • 66
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • Zhang B., et al. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J. Cell Biol. 1997, 139(5):1307-1315.
    • (1997) J. Cell Biol. , vol.139 , Issue.5 , pp. 1307-1315
    • Zhang, B.1


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