Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation

Journal of Biological Chemistry

Volumn 286, Issue 11, 2011, Pages 9049-9062

  Sun, Xiulian ^a,b   Wu, Yili ^a   Chen, Bin ^a   Zhang, Zhuohua ^c   Zhou, Weihui ^a   Tong, Yigang ^a   Yuan, Junying ^d   Xia, Kun ^e   Gronemeyer, Hinrich ^f   Flavell, Richard A ^g   Song, Weihong ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b SHANDONG UNIVERSITY   (China)

^c BURNHAM INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e CENTRAL SOUTH UNIVERSITY   (China)

^f INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; BRAIN REGIONS; CALCINEURIN; CASPASE-3; CASPASE-3 ACTIVATION; CASPASES; DEXAMETHASONES; DOWN SYNDROME; ISOFORMS; KNOCK OUTS; NEURODEGENERATION; NEUROFIBRILLARY TANGLES; NEURONAL APOPTOSIS; NEURONAL DEATH; NEURONAL LOSS; NEUROTOXICITY; OVER-EXPRESSION; PROMOTER REGION; RESPONSE ELEMENTS; STRESS HORMONES; UP-REGULATION;

BRAIN; GENES;

CELL DEATH;

AMYLOID BETA PROTEIN; CASPASE 3; CASPASE 9; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; REGULATOR OF CALCINEURIN 1; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CORTEX; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHROMOSOME 21; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOWN SYNDROME; EMBRYO; GENE OVEREXPRESSION; GLUCOCORTICOID RESPONSE ELEMENT; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; NERVE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; REGULATOR OF CALCINEURIN 1 GENE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; CASPASE 3; CEREBRAL CORTEX; CHROMOSOMES, HUMAN, PAIR 21; DOWN SYNDROME; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; NEURONS; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; RATS; RATS, WISTAR;

EID: 79953168726     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.177519     Document Type: Article

References (87)

1. Down, J. L. (1866) London Hospital Reports 3, 259-262
2. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 122, 1131-1135
3. Glenner, G. G., and Wong, C. W. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
4. Hardy, J., and Selkoe, D. J. (2002) Science 297, 353-356
5. Mattson, M. P. (2004) Nature 430, 631-639
6. Busciglio, J., and Yankner, B. A. (1995) Nature 378, 776-779
7. Stadelmann, C., Deckwerth, T. L., Srinivasan, A., Bancher, C., Brück, W., Jellinger, K., and Lassmann, H. (1999) Am. J. Pathol. 155, 1459-1466
8. Eckert, A., Marques, C. A., Keil, U., Schüssel, K., and Müller, W. E. (2003) Ann. N.Y. Acad. Sci. 1010, 604-609
9. Friedlander, R. M. (2003) N. Engl. J. Med. 348, 1365-1375
10. Jacobs, P. A., Baikie, A. G., Court Brown, W. M., and Strong, J. A. (1959) Lancet 1, 710
11. Lejeune, J., Turpin, R., and Gautier, M. (1959) Bull. Acad. Natl. Med. 143, 256-265
12. Reeves, R. H., Baxter, L. L., and Richtsmeier, J. T. (2001) Trends Genet. 17, 83-88
13. Fuentes, J. J., Pritchard, M. A., Planas, A. M., Bosch, A., Ferrer, I., and Estivill, X. (1995) Hum. Mol. Genet. 4, 1935-1944
14. Arron, J. R., Winslow, M. M., Polleri, A., Chang, C. P., Wu, H., Gao, X., Neilson, J. R., Chen, L., Heit, J. J., Kim, S. K., Yamasaki, N., Miyakawa, T., Francke, U., Graef, I. A., and Crabtree, G. R. (2006) Nature 441, 595-600
15. Chan, B., Greenan, G., McKeon, F., and Ellenberger, T. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 13075-13080
16. Rothermel, B. A., McKinsey, T. A., Vega, R. B., Nicol, R. L., Mammen, P., Yang, J., Antos, C. L., Shelton, J. M., Bassel-Duby, R., Olson, E. N., and Williams, R. S. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 3328-3333
17. Fuentes, J. J., Genescà, L., Kingsbury, T. J., Cunningham, K. W., Pérez-Riba, M., Estivill, X., and de la Luna, S. (2000) Hum. Mol. Genet. 9, 1681-1690
18. Rothermel, B., Vega, R. B., Yang, J., Wu, H., Bassel-Duby, R., and Williams, R. S. (2000) J. Biol. Chem. 275, 8719-8725
19. van Rooij, E., Doevendans, P. A., Crijns, H. J., Heeneman, S., Lips, D. J., van Bilsen, M., Williams, R. S., Olson, E. N., Bassel-Duby, R., Rothermel, B. A., and De Windt, L. J. (2004) Circ. Res. 94, e18-26
20. Davies, K. J., Ermak, G., Rothermel, B. A., Pritchard, M., Heitman, J., Ahnn, J., Henrique-Silva, F., Crawford, D., Canaider, S., Strippoli, P., Carinci, P., Min, K. T., Fox, D. S., Cunningham, K. W., Bassel-Duby, R., Olson, E. N., Zhang, Z., Williams, R. S., Gerber, H. P., Pérez-Riba, M., Seo, H., Cao, X., Klee, C. B., Redondo, J. M., Maltais, L. J., Bruford, E. A., Povey, S., Molkentin, J. D., McKeon, F. D., Duh, E. J., Crabtree, G. R., Cyert, M. S., de la Luna, S., and Estivill, X. (2007) FASEB J. 21, 3023-3028
21. Abbasi, S., Lee, J. D., Su, B., Chen, X., Alcon, J. L., Yang, J., Kellems, R. E., and Xia, Y. (2006) J. Biol. Chem. 281, 7717-7726
22. Abbasi, S., Su, B., Kellems, R. E., Yang, J., and Xia, Y. (2005) J. Biol. Chem. 280, 36737-36746
23. Hilioti, Z., Gallagher, D. A., Low-Nam, S. T., Ramaswamy, P., Gajer, P., Kingsbury, T. J., Birchwood, C. J., Levchenko, A., and Cunningham, K. W. (2004) Genes Dev. 18, 35-47
24. Vega, R. B., Yang, J., Rothermel, B. A., Bassel-Duby, R., and Williams, R. S. (2002) J. Biol. Chem. 277, 30401-30407
25. Genescà, L., Aubareda, A., Fuentes, J. J., Estivill, X., De La Luna, S., and Pérez-Riba, M. (2003) Biochem. J. 374, 567-575
26. Lin, H. Y., Michtalik, H. J., Zhang, S., Andersen, T. T., Van Riper, D. A., Davies, K. K., Ermak, G., Petti, L. M., Nachod, S., Narayan, A. V., Bhatt, N., and Crawford, D. R. (2003) Free Radic. Biol. Med. 35, 528-539
27. Lee, E. J., Seo, S. R., Um, J. W., Park, J., Oh, Y., and Chung, K. C. (2008) J. Biol. Chem. 283, 3392-3400
28. Liu, Q., Busby, J. C., and Molkentin, J. D. (2009) Nat. Cell Biol. 11, 154-161
29. Stathatos, N., Bourdeau, I., Espinosa, A. V., Saji, M., Vasko, V. V., Burman, K. D., Stratakis, C. A., and Ringel, M. D. (2005) J. Clin. Endocrinol. Metab. 90, 5432-5440
30. Minami, T., Horiuchi, K., Miura, M., Abid, M. R., Takabe, W., Noguchi, N., Kohro, T., Ge, X., Aburatani, H., Hamakubo, T., Kodama, T., and Aird, W. C. (2004) J. Biol. Chem. 279, 50537-50554
31. Cano, E., Canellada, A., Minami, T., Iglesias, T., and Redondo, J. M. (2005) J. Biol. Chem. 280, 29435-29443
32. Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P., and Flavell, R. A. (1996) Nature 384, 368-372
33. Sun, X., He, G., and Song, W. (2006) FASEB J. 20, 1369-1376
34. Sun, X., Wang, Y., Qing, H., Christensen, M. A., Liu, Y., Zhou, W., Tong, Y., Xiao, C., Huang, Y., Zhang, S., Liu, X., and Song, W. (2005) FASEB J. 19, 739-749
35. Christensen, M. A., Zhou, W., Qing, H., Lehman, A., Philipsen, S., and Song, W. (2004) Mol. Cell. Biol. 24, 865-874
36. Sun, X., He, G., Qing, H., Zhou, W., Dobie, F., Cai, F., Staufenbiel, M., Huang, L. E., and Song, W. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 18727-18732
37. Ma, H., Xiong, H., Liu, T., Zhang, L., Godzik, A., and Zhang, Z. (2004) J. Neurochem. 88, 1485-1496
38. Ermak, G., Morgan, T. E., and Davies, K. J. (2001) J. Biol. Chem. 276, 38787-38794
39. Cook, C. N., Hejna, M. J., Magnuson, D. J., and Lee, J. M. (2005) J. Alzheimers Dis. 8, 63-73
40. Harris, C. D., Ermak, G., and Davies, K. J. (2007) FEBS J. 274, 1715-1724
41. Yoshida, N. L., Miyashita, T. U. M., Yamada, M., Reed, J. C., Sugita, Y., and Oshida, T. (2002) Biochem. Biophys. Res. Commun. 293, 1254-1261
42. Kawata, M., Yuri, K., Ozawa, H., Nishi, M., Ito, T., Hu, Z., Lu, H., and Yoshida, M. (1998) J. Steroid Biochem. Mol. Biol. 65, 273-280
43. Fuentes, J. J., Pritchard, M. A., and Estivill, X. (1997) Genomics 44, 358-361
44. Ermak, G., Harris, C. D., and Davies, K. J. (2002) FASEB J. 16, 814-824
45. Hoeffer, C. A., Dey, A., Sachan, N., Wong, H., Patterson, R. J., Shelton, J. M., Richardson, J. A., Klann, E., and Rothermel, B. A. (2007) J. Neurosci. 27, 13161-13172
46. Yang, J., Rothermel, B., Vega, R. B., Frey, N., McKinsey, T. A., Olson, E. N., Bassel-Duby, R., and Williams, R. S. (2000) Circ. Res. 87, E61-E68
47. Baek, K. H., Zaslavsky, A., Lynch, R. C., Britt, C., Okada, Y., Siarey, R. J., Lensch, M. W., Park, I. H., Yoon, S. S., Minami, T., Korenberg, J. R., Folkman, J., Daley, G. Q., Aird, W. C., Galdzicki, Z., and Ryeom, S. (2009) Nature 459, 1126-1130
48. Hampton, T. (2005) JAMA 293, 284-285
49. Oh, M., Rybkin, I. I., Copeland, V., Czubryt, M. P., Shelton, J. M., van Rooij, E., Richardson, J. A., Hill, J. A., De Windt, L. J., Bassel-Duby, R., Olson, E. N., and Rothermel, B. A. (2005) Mol. Cell. Biol. 25, 6629-6638
50. Kluetzman, K. S., Perez, A. V., and Crawford, D. R. (2005) Biochem. Biophys. Res. Commun. 337, 595-601
51. Li, Y. P., Bushnell, A. F., Lee, C. M., Perlmutter, L. S., and Wong, S. K. (1996) Brain Res. 738, 196-204
52. Sousa, N., Paula-Barbosa, M. M., and Almeida, O. F. (1999) Neuroscience 89, 1079-1087
53. Shi, Y. (2002) Mol. Cell 9, 459-470
54. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
55. Yuan, J., Lipinski, M., and Degterev, A. (2003) Neuron 40, 401-413
56. Shi, Y. (2004) Cell 117, 855-858
57. Guo, Q., Fu, W., Xie, J., Luo, H., Sells, S. F., Geddes, J. W., Bondada, V., Rangnekar, V. M., and Mattson, M. P. (1998) Nat. Med. 4, 957-962
58. Su, J. H., Deng, G., and Cotman, C. W. (1997) J. Neuropathol. Exp. Neurol. 56, 86-93
59. Kitamura, Y., Shimohama, S., Kamoshima, W., Matsuoka, Y., Nomura, Y., and Taniguchi, T. (1997) Biochem. Biophys. Res. Commun. 232, 418-421
60. Nishimura, T., Akiyama, H., Yonehara, S., Kondo, H., Ikeda, K., Kato, M., Iseki, E., and Kosaka, K. (1995) Brain Res. 695, 137-145
61. Kitamura, Y., Shimohama, S., Kamoshima, W., Ota, T., Matsuoka, Y., Nomura, Y., Smith, M. A., Perry, G., Whitehouse, P. J., and Taniguchi, T. (1998) Brain Res. 780, 260-269
62. Lakhani, S. A., Masud, A., Kuida, K., Porter, G. A., Jr., Booth, C. J., Mehal, W. Z., Inayat, I., and Flavell, R. A. (2006) Science 311, 847-851
63. Jiang, X., and Wang, X. (2004) Annu. Rev. Biochem. 73, 87-106
64. Kang, S. J., Wang, S., Kuida, K., and Yuan, J. (2002) Cell Death Differ. 9, 1115-1125
65. Wang, S., Miura, M., Jung, Y. K., Zhu, H., Li, E., and Yuan, J. (1998) Cell 92, 501-509
66. Kang, S. J., Sanchez, I., Jing, N., and Yuan, J. (2003) J. Neurosci. 23, 5455-5460
67. Wang, S., Miura, M., Jung, Y., Zhu, H., Gagliardini, V., Shi, L., Greenberg, A. H., and Yuan, J. (1996) J. Biol. Chem. 271, 20580-20587
68. Alzheimer, A. (1906) Neurologisches Centralblatt 23, 1129-1136
69. Rothermel, B. A., Vega, R. B., and Williams, R. S. (2003) Trends Cardiovasc. Med. 13, 15-21
70. Chang, K. T., Shi, Y. J., and Min, K. T. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 15794-15799
71. Liu, H., Wang, P., Song, W., and Sun, X. (2009) FASEB J. 23, 3383-3392
72. Pomara, N., Greenberg, W. M., Branford, M. D., and Doraiswamy, P. M. (2003) Psychopharmacol. Bull. 37, 120-134
73. de Quervain, D. J., Henke, K., Aerni, A., Treyer, V., McGaugh, J. L., Berthold, T., Nitsch, R. M., Buck, A., Roozendaal, B., and Hock, C. (2003) Eur. J. Neurosci. 17, 1296-1302
74. Reagan, L. P., and McEwen, B. S. (1997) J. Chem. Neuroanat. 13, 149-167
75. Newcomer, J. W., Selke, G., Melson, A. K., Hershey, T., Craft, S., Richards, K., and Alderson, A. L. (1999) Arch. Gen. Psychiatry 56, 527-533
76. Newcomer, J. W., Craft, S., Askins, K., Hershey, T., Bardgett, M. E., Csernansky, J. G., Gagliardi, A. E., and Vogler, G. (1998) Psychoneuroendocrinology 23, 65-72
77. Tesco, G., Koh, Y. H., and Tanzi, R. E. (2003) J. Biol. Chem. 278, 46074-46080
78. Gervais, F. G., Xu, D., Robertson, G. S., Vaillancourt, J. P., Zhu, Y., Huang, J., LeBlanc, A., Smith, D., Rigby, M., Shearman, M. S., Clarke, E. E., Zheng, H., Van Der Ploeg, L. H., Ruffolo, S. C., Thornberry, N. A., Xanthoudakis, S., Zamboni, R. J., Roy, S., and Nicholson, D. W. (1999) Cell 97, 395-406
79. Porta, S., Serra, S. A., Huch, M., Valverde, M. A., Llorens, F., Estivill, X., Arbonés, M. L., and Martí, E. (2007) Hum. Mol. Genet. 16, 1039-1050
80. Wisniewski, K. E., Wisniewski, H. M., and Wen, G. Y. (1985) Ann. Neurol. 17, 278-282
81. Sun, X., Tong, Y., Qing, H., Chen, C. H., and Song, W. (2006) FASEB J. 20, 1361-1368
82. Görlach, J., Fox, D. S., Cutler, N. S., Cox, G. M., Perfect, J. R., and Heitman, J. (2000) EMBO J. 19, 3618-3629
83. Asai, A., Qiu, J., Narita, Y., Chi, S., Saito, N., Shinoura, N., Hamada, H., Kuchino, Y., and Kirino, T. (1999) J. Biol. Chem. 274, 34450-34458
84. Shibasaki, F., and McKeon, F. (1995) J. Cell Biol. 131, 735-743
85. Wang, H. G., Pathan, N., Ethell, I. M., Krajewski, S., Yamaguchi, Y., Shibasaki, F., McKeon, F., Bobo, T., Franke, T. F., and Reed, J. C. (1999) Science 284, 339-343
86. Sharkey, J., and Butcher, S. P. (1994) Nature 371, 336-339
87. Chang, K. T., and Min, K. T. (2005) Nat. Neurosci. 8, 1577-1585