-
1
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
10.1006/bbrc.1999.0897, 10381378
-
Frye RA. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem Biophys Res Commun 1999, 260(1):273-279. 10.1006/bbrc.1999.0897, 10381378.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, Issue.1
, pp. 273-279
-
-
Frye, R.A.1
-
2
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
10.1038/nature01960, 12939617
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003, 425(6954):191-196. 10.1038/nature01960, 12939617.
-
(2003)
Nature
, vol.425
, Issue.6954
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
3
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
10.1091/mbc.E05-01-0033, 1237069, 16079181
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005, 16(10):4623-4635. 10.1091/mbc.E05-01-0033, 1237069, 16079181.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
4
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
10.1126/science.1094637, 14976264
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303(5666):2011-2015. 10.1126/science.1094637, 14976264.
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
5
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
10.1038/nature03354, 15744310
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434(7029):113-118. 10.1038/nature03354, 15744310.
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
6
-
-
77954218572
-
Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells
-
10.1016/j.bbrc.2010.05.160, 20617556
-
Zhang HN, Li L, Gao P, Chen HZ, Zhang R, Wei YS, Liu DP, Liang CC. Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells. Biochem Biophys Res Commun 2010, 397(3):569-575. 10.1016/j.bbrc.2010.05.160, 20617556.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, Issue.3
, pp. 569-575
-
-
Zhang, H.N.1
Li, L.2
Gao, P.3
Chen, H.Z.4
Zhang, R.5
Wei, Y.S.6
Liu, D.P.7
Liang, C.C.8
-
7
-
-
0037108799
-
SIRT3, A human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
10.1073/pnas.222538099, 129731, 12374852
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP. SIRT3, A human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci U S A 2002, 99(21):13653-13658. 10.1073/pnas.222538099, 129731, 12374852.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.21
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
8
-
-
78651468722
-
Sirt3 Mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
10.1016/j.cell.2010.10.002, 3018849, 21094524
-
Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA. Sirt3 Mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010, 143(5):802-812. 10.1016/j.cell.2010.10.002, 3018849, 21094524.
-
(2010)
Cell
, vol.143
, Issue.5
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
9
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
10.1016/j.cmet.2010.11.015, 21109198
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 2010, 12(6):662-667. 10.1016/j.cmet.2010.11.015, 21109198.
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
10
-
-
33746228121
-
Sirtuins in aging and age-related disease
-
10.1016/j.cell.2006.07.002, 16873059
-
Longo VD, Kennedy BK. Sirtuins in aging and age-related disease. Cell 2006, 126(2):257-268. 10.1016/j.cell.2006.07.002, 16873059.
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 257-268
-
-
Longo, V.D.1
Kennedy, B.K.2
-
11
-
-
52749091816
-
SirT1 Gain of function increases energy efficiency and prevents diabetes in mice
-
10.1016/j.cmet.2008.08.014, 3222897, 18840364
-
Banks AS, Kon N, Knight C, Matsumoto M, Gutiérrez-Juárez R, Rossetti L, Gu W, Accili D. SirT1 Gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 2008, 8(4):333-341. 10.1016/j.cmet.2008.08.014, 3222897, 18840364.
-
(2008)
Cell Metab
, vol.8
, Issue.4
, pp. 333-341
-
-
Banks, A.S.1
Kon, N.2
Knight, C.3
Matsumoto, M.4
Gutiérrez-Juárez, R.5
Rossetti, L.6
Gu, W.7
Accili, D.8
-
12
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
10.1073/pnas.1111308108, 3167496, 21873205
-
Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR. Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci U S A 2011, 108(35):14608-14613. 10.1073/pnas.1111308108, 3167496, 21873205.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.35
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.D.3
Boucher, J.4
Lee, K.Y.5
Lombard, D.6
Verdin, E.M.7
Kahn, C.R.8
-
13
-
-
34547101692
-
The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats
-
10.1111/j.1478-3231.2007.01497.x, 17498258
-
Deng XQ, Chen LL, Li NX. The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats. Liver Int 2007, 27(5):708-715. 10.1111/j.1478-3231.2007.01497.x, 17498258.
-
(2007)
Liver Int
, vol.27
, Issue.5
, pp. 708-715
-
-
Deng, X.Q.1
Chen, L.L.2
Li, N.X.3
-
14
-
-
78751513117
-
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation
-
10.1042/BJ20100791, 3398511, 21044047
-
Kendrick AA, Choudhury M, Rahman SM, McCurdy CE, Friederich M, Van Hove JL, Watson PA, Birdsey N, Bao J, Gius D, Sack MN, Jing E, Kahn CR, Friedman JE, Jonscher KR. Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. Biochem J 2011, 433(3):505-514. 10.1042/BJ20100791, 3398511, 21044047.
-
(2011)
Biochem J
, vol.433
, Issue.3
, pp. 505-514
-
-
Kendrick, A.A.1
Choudhury, M.2
Rahman, S.M.3
McCurdy, C.E.4
Friederich, M.5
Van Hove, J.L.6
Watson, P.A.7
Birdsey, N.8
Bao, J.9
Gius, D.10
Sack, M.N.11
Jing, E.12
Kahn, C.R.13
Friedman, J.E.14
Jonscher, K.R.15
-
15
-
-
77950901103
-
Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure
-
10.1074/jbc.M109.090266, 2832987, 20089851
-
Tanno M, Kuno A, Yano T, Miura T, Hisahara S, Ishikawa S, Shimamoto K, Horio Y. Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure. J Biol Chem 2010, 285(11):8375-8382. 10.1074/jbc.M109.090266, 2832987, 20089851.
-
(2010)
J Biol Chem
, vol.285
, Issue.11
, pp. 8375-8382
-
-
Tanno, M.1
Kuno, A.2
Yano, T.3
Miura, T.4
Hisahara, S.5
Ishikawa, S.6
Shimamoto, K.7
Horio, Y.8
-
16
-
-
77449120223
-
Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
-
10.1074/jbc.M109.077271, 2823454, 19940131
-
Pillai VB, Sundaresan NR, Kim G, Gupta M, Rajamohan SB, Pillai JB, Samant S, Ravindra PV, Isbatan A, Gupta MP. Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 2010, 285(5):3133-3144. 10.1074/jbc.M109.077271, 2823454, 19940131.
-
(2010)
J Biol Chem
, vol.285
, Issue.5
, pp. 3133-3144
-
-
Pillai, V.B.1
Sundaresan, N.R.2
Kim, G.3
Gupta, M.4
Rajamohan, S.B.5
Pillai, J.B.6
Samant, S.7
Ravindra, P.V.8
Isbatan, A.9
Gupta, M.P.10
-
17
-
-
0037195528
-
Pathogenesis of feline diabetes mellitus
-
O'Brien TD. Pathogenesis of feline diabetes mellitus. Mol Cell Endocrinol 2002, 197(1-2):213-219.
-
(2002)
Mol Cell Endocrinol
, vol.197
, Issue.1-2
, pp. 213-219
-
-
O'Brien, T.D.1
-
18
-
-
67649397532
-
Hepatic lipidosis in cats
-
10.1016/j.cvsm.2009.03.003, 19524794
-
Armstrong PJ, Blanchard G. Hepatic lipidosis in cats. Vet Clin North Am Small Anim Pract 2009, 39(3):599-616. 10.1016/j.cvsm.2009.03.003, 19524794.
-
(2009)
Vet Clin North Am Small Anim Pract
, vol.39
, Issue.3
, pp. 599-616
-
-
Armstrong, P.J.1
Blanchard, G.2
-
19
-
-
33745617095
-
Feline models of type 2 diabetes mellitus
-
10.1093/ilar.47.3.234, 16804198
-
Henson MS, O'Brien TD. Feline models of type 2 diabetes mellitus. ILAR J 2006, 47(3):234-242. 10.1093/ilar.47.3.234, 16804198.
-
(2006)
ILAR J
, vol.47
, Issue.3
, pp. 234-242
-
-
Henson, M.S.1
O'Brien, T.D.2
-
20
-
-
77953289094
-
Structural basis for sirtuin function: what we know and what we don't
-
10.1016/j.bbapap.2009.09.009, 2886166, 19766737
-
Sanders BD, Jackson B, Marmorstein R. Structural basis for sirtuin function: what we know and what we don't. Biochim Biophys Acta 2010, 1804(8):1604-1616. 10.1016/j.bbapap.2009.09.009, 2886166, 19766737.
-
(2010)
Biochim Biophys Acta
, vol.1804
, Issue.8
, pp. 1604-1616
-
-
Sanders, B.D.1
Jackson, B.2
Marmorstein, R.3
-
21
-
-
0032823749
-
The conserved core of a human SIR2 homologue functions in yeast silencing
-
10.1091/mbc.10.9.3045, 25551, 10473645
-
Sherman JM, Stone EM, Freeman-Cook LL, Brachmann CB, Boeke JD, Pillus L. The conserved core of a human SIR2 homologue functions in yeast silencing. Mol Biol Cell 1999, 10(9):3045-3059. 10.1091/mbc.10.9.3045, 25551, 10473645.
-
(1999)
Mol Biol Cell
, vol.10
, Issue.9
, pp. 3045-3059
-
-
Sherman, J.M.1
Stone, E.M.2
Freeman-Cook, L.L.3
Brachmann, C.B.4
Boeke, J.D.5
Pillus, L.6
-
22
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
10.1016/S0092-8674(01)00317-8, 11336676
-
Min J, Landry J, Sternglanz R, Xu RM. Crystal structure of a SIR2 homolog-NAD complex. Cell 2001, 105(2):269-279. 10.1016/S0092-8674(01)00317-8, 11336676.
-
(2001)
Cell
, vol.105
, Issue.2
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.M.4
-
23
-
-
17144424946
-
SIRT3, A mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
10.1074/jbc.M414670200, 15653680
-
Shi T, Wang F, Stieren E, Tong Q. SIRT3, A mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 2005, 280(14):13560-13567. 10.1074/jbc.M414670200, 15653680.
-
(2005)
J Biol Chem
, vol.280
, Issue.14
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
24
-
-
80052582877
-
Bovine sirtuins: initial characterization and expression of sirtuins 1 and 3 in liver, muscle, and adipose tissue
-
10.2527/jas.2010-3476, 21421831
-
Ghinis-Hozumi Y, González-Gallardo A, González-Dávalos L, Antaramian A, Villarroya F, Shimada A, Varela-Echavarría A, Mora O. Bovine sirtuins: initial characterization and expression of sirtuins 1 and 3 in liver, muscle, and adipose tissue. J Anim Sci 2011, 89(8):2529-2536. 10.2527/jas.2010-3476, 21421831.
-
(2011)
J Anim Sci
, vol.89
, Issue.8
, pp. 2529-2536
-
-
Ghinis-Hozumi, Y.1
González-Gallardo, A.2
González-Dávalos, L.3
Antaramian, A.4
Villarroya, F.5
Shimada, A.6
Varela-Echavarría, A.7
Mora, O.8
-
25
-
-
66949172833
-
Molecular cloning and characterization of porcine sirtuin genes
-
10.1016/j.cbpb.2009.04.004, 19389481
-
Jin D, Tan HJ, Lei T, Gan L, Chen XD, Long QQ, Feng B, Yang ZQ. Molecular cloning and characterization of porcine sirtuin genes. Comp Biochem Physiol B Biochem Mol Biol 2009, 153(4):348-358. 10.1016/j.cbpb.2009.04.004, 19389481.
-
(2009)
Comp Biochem Physiol B Biochem Mol Biol
, vol.153
, Issue.4
, pp. 348-358
-
-
Jin, D.1
Tan, H.J.2
Lei, T.3
Gan, L.4
Chen, X.D.5
Long, Q.Q.6
Feng, B.7
Yang, Z.Q.8
-
26
-
-
77954515012
-
Lack of SIRT1 (mammalian sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation
-
10.1210/en.2009-1013, 2875813, 20339025
-
Xu F, Gao Z, Zhang J, Rivera CA, Yin J, Weng J, Ye J. Lack of SIRT1 (mammalian sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. Endocrinology 2010, 151(6):2504-2514. 10.1210/en.2009-1013, 2875813, 20339025.
-
(2010)
Endocrinology
, vol.151
, Issue.6
, pp. 2504-2514
-
-
Xu, F.1
Gao, Z.2
Zhang, J.3
Rivera, C.A.4
Yin, J.5
Weng, J.6
Ye, J.7
-
27
-
-
80555142897
-
Sirt1 Enhances skeletal muscle insulin sensitivity in mice during caloric restriction
-
10.1172/JCI58554, 3204844, 21985785
-
Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM. Sirt1 Enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest 2011, 121(11):4281-4288. 10.1172/JCI58554, 3204844, 21985785.
-
(2011)
J Clin Invest
, vol.121
, Issue.11
, pp. 4281-4288
-
-
Schenk, S.1
McCurdy, C.E.2
Philp, A.3
Chen, M.Z.4
Holliday, M.J.5
Bandyopadhyay, G.K.6
Osborn, O.7
Baar, K.8
Olefsky, J.M.9
-
28
-
-
70349208608
-
Sirt3 Blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
2735933, 19652361
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP. Sirt3 Blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 2009, 119(9):2758-2771. 2735933, 19652361.
-
(2009)
J Clin Invest
, vol.119
, Issue.9
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
29
-
-
77954036640
-
Feline hypertrophic cardiomyopathy: an update
-
10.1016/j.cvsm.2010.04.004, 20610019
-
Abbott JA. Feline hypertrophic cardiomyopathy: an update. Vet Clin North Am Small Anim Pract 2010, 40(4):685-700. 10.1016/j.cvsm.2010.04.004, 20610019.
-
(2010)
Vet Clin North Am Small Anim Pract
, vol.40
, Issue.4
, pp. 685-700
-
-
Abbott, J.A.1
-
30
-
-
33244486764
-
Sirt1 Regulates insulin secretion by repressing UCP2 in pancreatic beta cells
-
10.1371/journal.pbio.0040031, 1318478, 16366736
-
Bordone L, Motta MC, Picard F, Robinson A, Jhala US, Apfeld J, McDonagh T, Lemieux M, McBurney M, Szilvasi A, Easlon EJ, Lin SJ, Guarente L. Sirt1 Regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol 2006, 4(2):e31. 10.1371/journal.pbio.0040031, 1318478, 16366736.
-
(2006)
PLoS Biol
, vol.4
, Issue.2
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
Robinson, A.4
Jhala, U.S.5
Apfeld, J.6
McDonagh, T.7
Lemieux, M.8
McBurney, M.9
Szilvasi, A.10
Easlon, E.J.11
Lin, S.J.12
Guarente, L.13
-
31
-
-
84876502959
-
Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
-
10.1007/s00125-013-2851-y, 23397292
-
Caton PW, Richardson SJ, Kieswich J, Bugliani M, Holland ML, Marchetti P, Morgan NG, Yaqoob MM, Holness MJ, Sugden MC. Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients. Diabetologia 2013, 56(5):1068-1077. 10.1007/s00125-013-2851-y, 23397292.
-
(2013)
Diabetologia
, vol.56
, Issue.5
, pp. 1068-1077
-
-
Caton, P.W.1
Richardson, S.J.2
Kieswich, J.3
Bugliani, M.4
Holland, M.L.5
Marchetti, P.6
Morgan, N.G.7
Yaqoob, M.M.8
Holness, M.J.9
Sugden, M.C.10
-
32
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
10.1126/science.1099196, 15205477
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004, 305(5682):390-392. 10.1126/science.1099196, 15205477.
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
de Cabo, R.9
Sinclair, D.A.10
-
33
-
-
84864678390
-
High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction
-
10.1016/j.cmet.2012.07.003, 3539750, 22883230
-
Chalkiadaki A, Guarente L. High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction. Cell Metab 2012, 16(2):180-188. 10.1016/j.cmet.2012.07.003, 3539750, 22883230.
-
(2012)
Cell Metab
, vol.16
, Issue.2
, pp. 180-188
-
-
Chalkiadaki, A.1
Guarente, L.2
-
34
-
-
33845866857
-
Inflammation and metabolic disorders
-
10.1038/nature05485, 17167474
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006, 444(7121):860-867. 10.1038/nature05485, 17167474.
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
35
-
-
84882619016
-
Companion animals symposium: obesity in dogs and cats: what is wrong with being fat?
-
10.2527/jas.2011-4571, 21984724
-
Laflamme DP. Companion animals symposium: obesity in dogs and cats: what is wrong with being fat?. J Anim Sci 2012, 90(5):1653-1662. 10.2527/jas.2011-4571, 21984724.
-
(2012)
J Anim Sci
, vol.90
, Issue.5
, pp. 1653-1662
-
-
Laflamme, D.P.1
-
36
-
-
77349087078
-
SIRT1 Inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
-
10.1152/ajpendo.00417.2009, 2838524, 19996381
-
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. SIRT1 Inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. Am J Physiol Endocrinol Metab 2010, 298(3):E419-E428. 10.1152/ajpendo.00417.2009, 2838524, 19996381.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, Issue.3
-
-
Yoshizaki, T.1
Schenk, S.2
Imamura, T.3
Babendure, J.L.4
Sonoda, N.5
Bae, E.J.6
Oh, D.Y.7
Lu, M.8
Milne, J.C.9
Westphal, C.10
Bandyopadhyay, G.11
Olefsky, J.M.12
|