Bovine sirtuins: Initial characterization and expression of sirtuins 1 and 3 in liver, muscle, and adipose tissue

Journal of Animal Science

Volumn 89, Issue 8, 2011, Pages 2529-2536

  Ghinis Hozumi, Y ^a   Gonzalez Gallardo A ^b   Gonzalez Davalos L ^c   Antaramian, A ^b   Villarroya, F ^d   Shimada, A ^c   Varela Echavarria A ^b   Mora, O ^c  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO DE NEUROBIOLOGÍA   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Adipose tissue; Bovine; Expression; Liver; Muscle; Sequence; Sirtuin

Indexed keywords

MESSENGER RNA; SIRTUIN;

ADIPOSE TISSUE; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CATTLE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LIVER; MALE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SKELETAL MUSCLE;

ADIPOSE TISSUE; AMINO ACID SEQUENCE; ANIMALS; CATTLE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LIVER; MALE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; RNA, MESSENGER; SIRTUINS;

ANIMALIA; BOVINAE; MAMMALIA; SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 80052582877     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2010-3476     Document Type: Article

References (47)

1. Ahn, B. H., H. S. Kim, S. Song, I. H. Lee, J. Liu, A. Vassilopoulos, C. X. Deng, and T. Finkel. 2008. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc. Natl. Acad. Sci. USA 105:14447-14452.
2. Alcendor, R. R., S. Gao, P. Zhai, D. Zablocki, E. Holle, X. Yu, B. Tian, T. Wagner, S. F. Vatner, and J. Sadoshima. 2007. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ. Res. 100:1512-1521.
3. Altschul, S. F., T. L. Madden, A. A. Schäffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSIBLAST: A new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
4. Chen, D., J. Bruno, E. Easlon, S.-J. Lin, H.-L. Cheng, F. W. Alt, and L. Guarente. 2008. Tissue-specific regulation of SIRT1 by calorie restriction. Genes Dev. 22:1753-1757.
5. Cohen, H. Y., C. Miller, K. J. Bitterman, N. R. Wall, B. Hekking, B. Kessler, K. T. Howitz, M. Gorospe, R. de Cabo, and D. A. Sinclair. 2004. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305:390-392.
6. Dali-Youcef, N., M. Lagouge, S. Froelich, C. Koehl, K. Schoonjans, and J. Auwerx. 2007. Sirtuins: The 'magnificent seven,' function, metabolism and longevity. Ann. Med. 39:335-345.
7. Dieffenbach, C. W., T. M. Lowe, and G. S. Dveksler. 1993. General concepts for PCR primer design. PCR Methods Appl. 3:S30-S37.
8. Drummond, A. J., B. Ashton, S. Buxton, M. Cheung, J. Heled, M. Kearse, R. Moir, S. Stones-Havas, S. Sturrock, T. Thierer, and A. Wilson. 2010. Geneious version 5.0. Accessed Mar. 4, 2011. http://www.geneious.com.
9. Ferrara, N., B. Rinaldi, G. Corbi, V. Conti, P. Stiuso, S. Boccuti, G. Rengo, F. Rossi, and A. Filippelli. 2008. Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res. 11:139-150.
10. Frye, R. A. 1999. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260:273-279.
11. Gerhart-Hines, Z., J. T. Rodgers, O. Bare, C. Lerin, S.-H. Kim, R. Mostoslavsky, F. W. Alt, Z. Wu, and P. Puigserver. 2007. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1a. EMBO J. 26:1913-1923.
12. Gille, C., and C. Frömmel. 2001. STRAP: Editor for STRuctural Alignments of Proteins. Bioinformatics 17:377-378.
13. Hallows, W. C., S. Lee, and J. M. Denu. 2006. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc. Natl. Acad. Sci. USA 103:10230-10235.
14. Hirschey, M. D., T. Shimazu, E. Goetzman, E. Jing, B. Schwer, D. B. Lombard, C. A. Grueter, C. Harris, S. Biddinger, O. R. Ilkayeva, R. D. Stevens, Y. Li, A. K. Saha, N. B. Ruderman, J. R. Bain, C. B. Newgard, R. V. Farese Jr., F. W. Alt, C. R. Kahn, and E. Verdin. 2010. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 464:121-125.
15. Howarth, R. E., R. L. Baldwin, and M. Ronning. 1968. Enzyme activities in liver, muscle, and adipose tissue of calves and steers. J. Dairy Sci. 51:1270-1274.
16. Imai, S., and L. Guarente. 2010. Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases. Trends Pharmacol. Sci. 31:212-220.
17. Jin, D., H. J. Tan, T. Lei, L. Gan, X. D. Chen, Q. Q. Long, B. Feng, and Z. Q. Yang. 2009. Molecular cloning and characterization of porcine sirtuin genes. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 153:348-358.
18. Larkin, M. A., G. Blackshields, N. P. Brown, R. Chenna, P. A. Mc-Gettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, J. D. Thompson, T. J. Gibson, and D. G. Higgins. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23:2947-2948.
19. Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25:402-408.
20. Marchler-Bauer, A., J. B. Anderson, F. Chitsaz, M. K. Derbyshire, C. DeWeese-Scott, J. H. Fong, L. Y. Geer, R. C. Geer, N. R. Gonzales, M. Gwadz, S. He, D. I. Hurwitz, J. D. Jackson, Z. Ke, C. J. Lanczycki, C. A. Liebert, C. Liu, F. Lu, S. Lu, G. H. Marchler, M. Mullokandov, J. S. Song, A. Tasneem, N. Thanki, R. A. Yamashita, D. Zhang, N. Zhang, and S. H. Bryant. 2009. CDD: Specific functional annotation with the Conserved Domain Database. Nucleic Acids Res. 37:D205-D210.
21. Martin, R. J., L. L. Wilson, R. L. Cowan, and J. D. Sink. 1973. Effects of fasting and diet on enzyme profiles in ovine liver and adipose tissue. J. Anim. Sci. 36:101-106.
22. Meiler, J., and D. Baker. 2003. Coupled prediction of protein secondary and tertiary structure. Proc. Natl. Acad. Sci. USA 100:12105-12110.
23. Meiler, J., M. Mueller, A. Zeidler, and F. Schmaeschke. 2001. Generation and evaluation of dimension reduced amino acid parameter representations by artificial neural networks. J. Mol. Model. 7:360-369.
24. Miarelli, M., and F. Signorelli. 2010. Differential expression of liver proteins in Chianina and Holstein young bulls. J. Anim. Sci. 88:593-598.
25. Nafikov, R. A., and D. C. Beitz. 2007. Carbohydrate and lipid metabolism in farm animals. J. Nutr. 137:702-705.
26. Onyango, P., I. Celic, J. M. McCaffery, J. D. Boeke, and A. P. Feinberg. 2002. SIRT3, a human SIR2 homologue, is a NADdependent deacetylase localized to mitochondria. Proc. Natl. Acad. Sci. USA 99:13653-13658.
27. Picard, F., M. Kurtev, N. Chung, A. Topark-Ngarm, T. Senawong, R. Machado de Oliveira, M. Leid, M. W. McBurney, and L. Guarente. 2004. Sirt1 promotes fat mobilization in white adipocytes by repressing PPARγ. Nature 429:771-776.
28. Rodgers, J. T., C. Lerin, W. Haas, S. P. Gygi, B. M. Spiegelman, and P. Puigserver. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1. Nature 434:113-118.
29. Rodgers, J. T., and P. Puigserver. 2007. Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proc. Natl. Acad. Sci. USA 104:12861-12866.
30. SAGAR (Secretaría de Agricultura, Ganadería y Desarrollo Rural). 1997. Norma Oficial Mexicana NOM-033-ZOO-1995: Sacrificio humanitario de los animales domésticos y silvestres. Diario Oficial de la Federación. 16 de Julio. México.
31. SAGAR (Secretaría de Agricultura, Ganadería y Desarrollo Rural). 1998. Norma Oficial Mexicana NOM-051-ZOO-1995: Trato humanitario en la movilización de animales. Diario Oficial de la Federación. 23 de Marzo. México.
32. SAGARPA (Secretaría de Agricultura, Ganadería, Desarrollo Rural, Pesca y Alimentación). 2001. Norma Oficial Mexicana NOM-062-ZOO-1999: Especificaciones técnicas para la producción, cuidado y uso de los animales de laboratorio. Diario Oficial de la Federación. 22 de Agosto. México.
33. Sanders, B. D., B. Jackson, and R. Marmorstein. 2010. Structural basis for sirtuin function: What we know and what we don't. Biochim. Biophys. Acta 1804:1604-1616.
34. Saunders, L. R., and E. Verdin. 2007. Sirtuins: Critical regulators at the crossroads between cancer and aging. Oncogene 26:5489-5504.
35. Schlicker, C., M. Gertz, P. Papatheodorou, B. Kachholz, C. F. W. Becker, and C. Steegborn. 2008. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J. Mol. Biol. 382:790-801.
36. Schmittgen, T. D., and K. J. Livak. 2008. Analyzing real-time PCR data by the comparative CT method. Nat. Protoc. 3:1101-1108.
37. Schwer, B., B. J. North, R. A. Frye, M. Ott, and E. Verdin. 2002. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotidedependent deacetylase. J. Cell Biol. 158:647-657.
38. Shan, T., Y. Wang, T. Wu, C. Liu, J. Guo, Y. Zhang, J. Liu, and Z. Xu. 2009. Porcine sirtuin 1 gene clone, expression pattern, and regulation by resveratrol. J. Anim. Sci. 87:895-904.
39. Sherman, J. M., E. M. Stone, L. L. Freeman-Cook, C. B. Brachmann, J. D. Boeke, and L. Pillus. 1999. The conserved core of a human SIR2 homologue functions in yeast silencing. Mol. Biol. Cell 10:3045-3059.
40. Shi, T., F. Wang, E. Stieren, and Q. Tong. 2005. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J. Biol. Chem. 280:13560-13567.
41. Shimada, A. 2003. Animal Nutrition. Ed. Trillas, Mexico City, Mexico.
42. Shoba, B., Z. M. Lwin, L. S. Ling, B. H. Bay, G. W. Yip, and S. D. Kumar. 2009. Function of sirtuins in biological tissues. Anat. Rec. (Hoboken) 292:536-543.
43. Vandesompele, J., K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, and F. Speleman. 2002. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3:Research0034.1-0034.12.
44. Wang, F., and Q. Tong. 2009. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARγ. Mol. Biol. Cell 20:801-808.
45. Yamamoto, H., K. Schoonjans, and J. Auwerx. 2007. Sirtuin functions in health and disease. Mol. Endocrinol. 21:1745-1755.
46. Yu, J., and J. Auwerx. 2009. The role of sirtuins in the control of metabolic homeostasis. Ann. N. Y. Acad. Sci. 1173:E10-E19.
47. Zimin, A. V., A. L. Delcher, L. Florea, D. R. Kelley, M. C. Schatz, D. Puiu, R. Hanrahan, G. Pertea, C. P. Van Tassell, T. S. Sonstegard, G. Marçais, M. Roberts, P. Subramanian, J. A. Yorke, and S. L. Salzberg. 2009. A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol. 10:R42.