-
1
-
-
33846205518
-
The peripheral benzodiazepine receptor (Translocator protein 18 kDa) in microglia: From pathology to imaging
-
DOI 10.1016/j.pneurobio.2006.10.002, PII S0301008206001316
-
Venneti, S., Lopresti, B. J., and Wiley, C. A. (2006) The peripheral benzodiazepine receptor (Translocator protein 18 kDa) in microglia: from pathology to imaging Prog. Neurobiol. 80, 308-322 (Pubitemid 46107737)
-
(2006)
Progress in Neurobiology
, vol.80
, Issue.6
, pp. 308-322
-
-
Venneti, S.1
Lopresti, B.J.2
Wiley, C.A.3
-
2
-
-
79960784323
-
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity
-
Kraft, A. D. and Harry, G. J. (2011) Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity Int. J. Environ. Res. Public Health 8, 2980-3018
-
(2011)
Int. J. Environ. Res. Public Health
, vol.8
, pp. 2980-3018
-
-
Kraft, A.D.1
Harry, G.J.2
-
3
-
-
84855280767
-
Biomarkers for microglial activation in Alzheimer's disease
-
Art. ID 939426, doi: 10.4061/2011/939426
-
Lautner, R., Mattsson, N., Scholl, M., Augutis, K., Blennow, K., Olsson, B., and Zetterberg, H. (2011) Biomarkers for microglial activation in Alzheimer's disease. Int. J. Alzheimers Dis., Art. ID 939426, doi: 10.4061/2011/939426
-
(2011)
Int. J. Alzheimers Dis.
-
-
Lautner, R.1
Mattsson, N.2
Scholl, M.3
Augutis, K.4
Blennow, K.5
Olsson, B.6
Zetterberg, H.7
-
4
-
-
81755173570
-
Role of microglia in CNS inflammation
-
Graeber, M. B., Li, W., and Rodriguez, M. L. (2011) Role of microglia in CNS inflammation FEBS Lett. 585, 3798-3805
-
(2011)
FEBS Lett.
, vol.585
, pp. 3798-3805
-
-
Graeber, M.B.1
Li, W.2
Rodriguez, M.L.3
-
5
-
-
77950858637
-
Microglia in neurodegenerative disease
-
Perry, V. H., Nicoll, J. A., and Holmes, C. (2010) Microglia in neurodegenerative disease Nat. Rev. Neurol. 6 (4) 193-201
-
(2010)
Nat. Rev. Neurol.
, vol.6
, Issue.4
, pp. 193-201
-
-
Perry, V.H.1
Nicoll, J.A.2
Holmes, C.3
-
7
-
-
0035845283
-
In-vivo measurement of activated microglia in dementia
-
DOI 10.1016/S0140-6736(01)05625-2
-
Cagnin, A., Brooks, D. J., Kennedy, A. M., Gunn, R. N., Myers, R., and Turkheimer, F. E. (2001) In-vivo measurement of activated microglia in dementia Lancet 358, 461-467 (Pubitemid 32769854)
-
(2001)
Lancet
, vol.358
, Issue.9280
, pp. 461-467
-
-
Cagnin, A.1
Brooks, D.J.2
Kennedy, A.M.3
Gunn, R.N.4
Myers, R.5
Turkheimer, F.E.6
Jones, T.7
Banati, R.B.8
-
8
-
-
80052895269
-
Recent advances in positron emission tomography imaging of brain
-
Seneca, N. (2011) Recent advances in positron emission tomography imaging of brain Drug Future 36, 601-613
-
(2011)
Drug Future
, vol.36
, pp. 601-613
-
-
Seneca, N.1
-
9
-
-
83155164537
-
Recent advances in ligand targeted therapy
-
Trapani, G., Denora, N., Trapani, A., and Laquintana, V. (2012) Recent advances in ligand targeted therapy J. Drug Target. 20, 1-22
-
(2012)
J. Drug Target.
, vol.20
, pp. 1-22
-
-
Trapani, G.1
Denora, N.2
Trapani, A.3
Laquintana, V.4
-
10
-
-
33746035655
-
Translocator protein (18 kDa): New nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
-
DOI 10.1016/j.tips.2006.06.005, PII S0165614706001532
-
Papadopoulos, V., Baraldi, M., Guilarte, T. R., Knudsen, T. B., Lacapere, J. J., Lindemann, P., Norenberg, M. D., Nutt, D., Weizman, A., Zhang, M. R., and Gavish, M. (2006) Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function Trends Pharmacol. Sci. 27, 402-409 (Pubitemid 44069585)
-
(2006)
Trends in Pharmacological Sciences
, vol.27
, Issue.8
, pp. 402-409
-
-
Papadopoulos, V.1
Baraldi, M.2
Guilarte, T.R.3
Knudsen, T.B.4
Lacapere, J.-J.5
Lindemann, P.6
Norenberg, M.D.7
Nutt, D.8
Weizman, A.9
Zhang, M.-R.10
Gavish, M.11
-
11
-
-
78649687576
-
Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders
-
Rupprecht, R., Papadopoulos, V., Rammes, G., Baghai, T. C., Fan, J., Akula, N., Groyer, G., Adams, D., and Schumacher, M. (2010) Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders Nat. Rev. Drug Discovery 9, 971-988
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 971-988
-
-
Rupprecht, R.1
Papadopoulos, V.2
Rammes, G.3
Baghai, T.C.4
Fan, J.5
Akula, N.6
Groyer, G.7
Adams, D.8
Schumacher, M.9
-
12
-
-
0031893596
-
Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure
-
DOI 10.1074/jbc.273.4.2146
-
Joseph-Liauzun, E., Delmas, P., Shire, D., and Ferrara, P. (1998) Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure J. Biol. Chem. 273, 2146-2152 (Pubitemid 28069264)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.4
, pp. 2146-2152
-
-
Joseph-Liauzun, E.1
Delmas, P.2
Shire, D.3
Ferrara, P.4
-
13
-
-
77953560009
-
Three-dimensional structure of TSPO by electron cryomicroscopy of helical crystals
-
Korkhov, V. M., Sachse, C., Short, J. M., and Tate, C. G. (2010) Three-dimensional structure of TSPO by electron cryomicroscopy of helical crystals Structure 18, 677-687
-
(2010)
Structure
, vol.18
, pp. 677-687
-
-
Korkhov, V.M.1
Sachse, C.2
Short, J.M.3
Tate, C.G.4
-
14
-
-
34548238745
-
Channel-like functions of the 18-kDA translocator protein (TSPO): Regulation of apoptosis and steroidogenesis as part of the host-defense response
-
DOI 10.2174/138161207781368710
-
Veenman, L., Papadopoulos, V., and Gavish, M. (2007) Channel-like functions of the 18-kDa Translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response Curr. Pharm. Des. 13, 2385-2405 (Pubitemid 47321571)
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.23
, pp. 2385-2405
-
-
Veenman, L.1
Papadopoulos, V.2
Gavish, M.3
-
15
-
-
0036494315
-
Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo
-
Decaudin, D., Castedo, M., Nemati, F., Beurdeley-Thomas, A., De Pinieux, G., Caron, A., Pouillart, P., Wijdenes, J., Rouillard, D., Kroemer, G., and Poupon, M.-F. (2002) Peripheral Benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo Cancer Res. 62, 1388-1393 (Pubitemid 34407797)
-
(2002)
Cancer Research
, vol.62
, Issue.5
, pp. 1388-1393
-
-
Decaudin, D.1
Castedo, M.2
Nemati, F.3
Beurdeley-Thomas, A.4
De Pinieux, G.5
Caron, A.6
Pouillart, P.7
Wijdenes, J.8
Rouillard, D.9
Kroemer, G.10
Poupon, M.-F.11
-
16
-
-
0034063730
-
Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity
-
DOI 10.1046/j.1471-4159.2000.0741694.x
-
Kuhlmann, A. C. and Guilarte, T. R. (2000) Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity J. Neurochem. 74, 1694-1704 (Pubitemid 30163992)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.4
, pp. 1694-1704
-
-
Kuhlmann, A.C.1
Guilarte, T.R.2
-
17
-
-
34250627649
-
Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor
-
DOI 10.1016/j.brainres.2007.04.054, PII S0006899307009183
-
Maeda, J., Higuchi, M., Inaji, M., Ji, B., Haneda, E., Okauchi, T., Zhang, M. R., Suzuki, K., and Suhara, T. (2007) Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor Brain Res. 1157, 100-111 (Pubitemid 46935074)
-
(2007)
Brain Research
, vol.1157
, Issue.1
, pp. 100-111
-
-
Maeda, J.1
Higuchi, M.2
Inaji, M.3
Ji, B.4
Haneda, E.5
Okauchi, T.6
Zhang, M.-R.7
Suzuki, K.8
Suhara, T.9
-
18
-
-
0028358646
-
11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats
-
DOI 10.1016/0969-8051(94)90022-1
-
Shah, F., Hume, S. P., Pike, V. W., Ashworth, S., and McDermott, J. (1994) Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats Nucl. Med. Biol. 21, 573-581 (Pubitemid 24173248)
-
(1994)
Nuclear Medicine and Biology
, vol.21
, Issue.4
, pp. 573-581
-
-
Shah, F.1
Hume, S.P.2
Pike, V.W.3
Ashworth, S.4
McDermott, J.5
-
19
-
-
0036850086
-
Visualising microglial activation in vivo
-
DOI 10.1002/glia.10144
-
Banati, R. B. (2002) Visualising microglial activation in vivo Glia 40, 206-217 (Pubitemid 35337378)
-
(2002)
GLIA
, vol.40
, Issue.2
, pp. 206-217
-
-
Banati, R.B.1
-
20
-
-
78349311533
-
PET tracers for the peripheral benzodiazepine receptor and uses thereof
-
Schweitzer, P. J., Fallon, B. A., Mann, J. J., and Dileep Kumar, J. S. (2010) PET tracers for the peripheral benzodiazepine receptor and uses thereof Drug Discovery Today 15, 933-942
-
(2010)
Drug Discovery Today
, vol.15
, pp. 933-942
-
-
Schweitzer, P.J.1
Fallon, B.A.2
Mann, J.J.3
Dileep Kumar, J.S.4
-
21
-
-
0036896309
-
In vivo imaging of neuroinflammation
-
DOI 10.1016/S0924-977X(02)00107-4, PII S0924977X02001074
-
Cagnin, A., Gerhard, A., and Banati, R. B. (2002) In vivo imaging of neuroinflammation Eur. Neuropsychopharmacol. 12, 581-586 (Pubitemid 35408707)
-
(2002)
European Neuropsychopharmacology
, vol.12
, Issue.6
, pp. 581-586
-
-
Cagnin, A.1
Gerhard, A.2
Banati, R.B.3
-
22
-
-
59649098348
-
PET imaging of the peripheral benzodiazepine receptor: Monitoring disease progression and therapy response in neurodegenerative disorders
-
Doorduin, J., deVries, E. F. J., Dierckx, R. A., and Klein, H. C. (2008) PET imaging of the peripheral benzodiazepine receptor: monitoring disease progression and therapy response in neurodegenerative disorders Curr. Pharm. Des. 14, 3297-3315
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 3297-3315
-
-
Doorduin, J.1
Devries, E.F.J.2
Dierckx, R.A.3
Klein, H.C.4
-
23
-
-
80055083184
-
Imaging brain microglial activation using positron emission tomography and translocator protein-specific radioligands
-
Owen, D. R. J. and Matthews, P. M. (2011) Imaging brain microglial activation using positron emission tomography and translocator protein-specific radioligands Int. Rev. Neurobiol. 101, 19-39
-
(2011)
Int. Rev. Neurobiol.
, vol.101
, pp. 19-39
-
-
Owen, D.R.J.1
Matthews, P.M.2
-
24
-
-
0028784323
-
PET of peripheral benzodiazepine binding sites in the microgliosis of Alzheimer's disease
-
Groom, G. N., Junck, L., Foster, N. L., Frey, K. A., and Kuhl, D. E. (1995) PET of peripheral benzodiazepine binding sites in the microgliosis of Alzheimer's disease J. Nucl. Med. 36, 2207-2210
-
(1995)
J. Nucl. Med.
, vol.36
, pp. 2207-2210
-
-
Groom, G.N.1
Junck, L.2
Foster, N.L.3
Frey, K.A.4
Kuhl, D.E.5
-
25
-
-
56349144614
-
11C]PIB-PET study
-
11C]PIB-PET study Neurobiol. Dis. 32, 412-419
-
(2008)
Neurobiol. Dis.
, vol.32
, pp. 412-419
-
-
Edison, P.1
Archer, H.A.2
Gerhard, A.3
Hinz, R.4
Pavese, N.5
Turkheimer, F.E.6
Hammers, A.7
Tai, Y.F.8
Fox, N.9
Kennedy, A.10
Rossor, M.11
Brooks, D.J.12
-
26
-
-
30744472146
-
11C](R)-PK11195 PET in idiopathic Parkinson's disease
-
DOI 10.1016/j.nbd.2005.08.002, PII S0969996105002263
-
[11C](R)-PK11195 PET in idiopathic Parkinson's disease Neurobiol. Dis. 21, 404-412 (Pubitemid 43099863)
-
(2006)
Neurobiology of Disease
, vol.21
, Issue.2
, pp. 404-412
-
-
Gerhard, A.1
Pavese, N.2
Hotton, G.3
Turkheimer, F.4
Es, M.5
Hammers, A.6
Eggert, K.7
Oertel, W.8
Banati, R.B.9
Brooks, D.J.10
-
27
-
-
0033768486
-
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: Quantitative in vivo imaging of microglia as a measure of disease activity
-
Banati, R. B., Newcombe, J., Gunn, R. N., Cagnin, A., Turkheimer, F., Heppner, F., Price, G., Wegner, F., Giovannoni, G., Miller, D. H., Perkin, G. D., Smith, T., Hewson, A. K., Bydder, G., Kreutzberg, G. W., Jones, T., Cuzner, M. L., and Myers, R. (2000) The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity Brain 123, 2321-2337
-
(2000)
Brain
, vol.123
, pp. 2321-2337
-
-
Banati, R.B.1
Newcombe, J.2
Gunn, R.N.3
Cagnin, A.4
Turkheimer, F.5
Heppner, F.6
Price, G.7
Wegner, F.8
Giovannoni, G.9
Miller, D.H.10
Perkin, G.D.11
Smith, T.12
Hewson, A.K.13
Bydder, G.14
Kreutzberg, G.W.15
Jones, T.16
Cuzner, M.L.17
Myers, R.18
-
28
-
-
79953179303
-
Cortical microglial activation is associated with disability in secondary progressive multiple sclerosis: An in vivo imaging study
-
Politis, M., Giannetti, P., Su, P., Turkheimer, F., Keihaninejad, S., Wu, K., Waldman, A., Reynolds, R., Nicholas, R., and Piccini, P. (2010) Cortical microglial activation is associated with disability in secondary progressive multiple sclerosis: an in vivo imaging study Neurology 74 (Suppl. 2) A290
-
(2010)
Neurology
, vol.74
, Issue.SUPPL. 2
, pp. 290
-
-
Politis, M.1
Giannetti, P.2
Su, P.3
Turkheimer, F.4
Keihaninejad, S.5
Wu, K.6
Waldman, A.7
Reynolds, R.8
Nicholas, R.9
Piccini, P.10
-
29
-
-
79251643906
-
Imaging of microglia activation in stroke
-
Thiel, A. and Heiss, W.-D. (2011) Imaging of microglia activation in stroke Stroke 42, 507-512
-
(2011)
Stroke
, vol.42
, pp. 507-512
-
-
Thiel, A.1
Heiss, W.-D.2
-
30
-
-
16244422002
-
11C](R)-PK11195 PET study
-
DOI 10.1016/j.neuroimage.2004.09.034, PII S1053811904005610
-
11C](R)- PK11195 PET study Neuroimage 24, 591-595 (Pubitemid 41359057)
-
(2005)
NeuroImage
, vol.24
, Issue.2
, pp. 591-595
-
-
Gerhard, A.1
Schwarz, J.2
Myers, R.3
Wise, R.4
Banati, R.B.5
-
31
-
-
27144462689
-
11C]-R-PK11195 in patients with AIDS
-
DOI 10.1080/13550280500187351
-
11C]-R-PK11195 in patients with AIDS J. Neurovirol. 11, 346-355 (Pubitemid 41614514)
-
(2005)
Journal of NeuroVirology
, vol.11
, Issue.4
, pp. 346-355
-
-
Hammoud, D.A.1
Endres, C.J.2
Chander, A.R.3
Guilarte, T.R.4
Wong, D.F.5
Sacktor, N.C.6
McArthur, J.C.7
Pomper, M.G.8
-
32
-
-
33748666903
-
Positron emission tomography imaging of peripheral benzodiazepine receptor binding in human immunodeficiency virus-infected subjects with and without cognitive impairment
-
DOI 10.1080/13550280600873868, PII H314X724L23177L0
-
Wiley, C. A., Lopresti, B. J., Becker, J. T., Boada, F., Lopez, O. L., Mellors, J., Meltzer, C. C., Wisniewski, S. R., and Mathis, C. A. (2006) Positron emission tomography imaging of peripheral benzodiazepine receptor binding in humans immunodeficiency virus-infected subjects with and without cognitive impairment J. Neurovirol. 12, 262-271 (Pubitemid 44382978)
-
(2006)
Journal of NeuroVirology
, vol.12
, Issue.4
, pp. 262-271
-
-
Wiley, C.A.1
Lopresti, B.J.2
Becker, J.T.3
Boada, F.4
Lopez, O.L.5
Mellors, J.6
Meltzer, C.C.7
Wisniewski, S.R.8
Mathis, C.A.9
-
33
-
-
80755185727
-
Glial cells in amyotrophic lateral sclerosis
-
Lasiene, J. and Yamanaka, K. (2011) Glial cells in amyotrophic lateral sclerosis Neurol. Res. Int. 718987
-
(2011)
Neurol. Res. Int.
, pp. 718987
-
-
Lasiene, J.1
Yamanaka, K.2
-
34
-
-
78651422988
-
Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study
-
Politis, M., Pavese, N., Tai, Y. F., Kiferle, L., Mason, S. L., Brooks, D. J., Tabrizi, S. J., Barker, R. A, and Piccini, P. (2011) Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study Human Brain Mapping 32, 258-270
-
(2011)
Human Brain Mapping
, vol.32
, pp. 258-270
-
-
Politis, M.1
Pavese, N.2
Tai, Y.F.3
Kiferle, L.4
Mason, S.L.5
Brooks, D.J.6
Tabrizi, S.J.7
Barker, R.A.8
Piccini, P.9
-
35
-
-
70350724581
-
Neuroinflammation in schizophrenia - Related psychosis A PET study
-
Doorduin, J., De Vries, E. F. J., Willemsen, A. T. M., De Groot, J. C., Dierckx, R. A., and Klein, H. C. (2009) Neuroinflammation in schizophrenia-related psychosis A PET study J. Nucl. Med. 50, 1801-1807
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 1801-1807
-
-
Doorduin, J.1
De Vries, E.F.J.2
Willemsen, A.T.M.3
De Groot, J.C.4
Dierckx, R.A.5
Klein, H.C.6
-
36
-
-
79955752123
-
The Translocator Protein
-
Scarf, A. M. and Kassiou, M. (2011) The Translocator Protein J. Nucl. Med. 52, 677-680
-
(2011)
J. Nucl. Med.
, vol.52
, pp. 677-680
-
-
Scarf, A.M.1
Kassiou, M.2
-
37
-
-
79953737531
-
In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa)
-
Chauveau, F., Boutin, H., Van Camp, N., Thominiaux, C., Hantraye, P., Rivron, L., Marguet, F., Castel, M. N., Rooney, T., Benavides, J., Dollé, F., and Tavitian, B. (2011) In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa) Eur. J. Nucl. Med. Mol. Imaging 38, 509-514
-
(2011)
Eur. J. Nucl. Med. Mol. Imaging
, vol.38
, pp. 509-514
-
-
Chauveau, F.1
Boutin, H.2
Van Camp, N.3
Thominiaux, C.4
Hantraye, P.5
Rivron, L.6
Marguet, F.7
Castel, M.N.8
Rooney, T.9
Benavides, J.10
Dollé, F.11
Tavitian, B.12
-
38
-
-
83455212272
-
Visualising neuroinflammation in post-stroke patients: A comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine
-
Gulyas, B., Toth, M., Vas, A., Shchukin, E., Kostulas, K., Hillert, J., and Halldin, C. (2012) Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine Curr. Radiopharm. 1, 19-28
-
(2012)
Curr. Radiopharm.
, vol.1
, pp. 19-28
-
-
Gulyas, B.1
Toth, M.2
Vas, A.3
Shchukin, E.4
Kostulas, K.5
Hillert, J.6
Halldin, C.7
-
39
-
-
79851473610
-
Mixed-affinity binding in humans with 18-kDa translocator protein ligands
-
Owen, D. R., Gunn, R. N., Rabiner, E. A., Bennacef, I., Fujita, M., Kreisl, W. C., Innis, R. B., Pike, V. W., Reynolds, R., Matthews, P. M., and Parker, C. A. (2011) Mixed-affinity binding in humans with 18-kDa translocator protein ligands J. Nucl. Med. 52, 24-32
-
(2011)
J. Nucl. Med.
, vol.52
, pp. 24-32
-
-
Owen, D.R.1
Gunn, R.N.2
Rabiner, E.A.3
Bennacef, I.4
Fujita, M.5
Kreisl, W.C.6
Innis, R.B.7
Pike, V.W.8
Reynolds, R.9
Matthews, P.M.10
Parker, C.A.11
-
40
-
-
54149105539
-
Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106
-
Yasuno, F., Ota, M., Kosaka, J., Ito, H., Higuchi, M., Doronbekov, T. K., Nozaki, S., Fujimura, Y., Koeda, M., Asada, T., and Suhara, T. (2008) Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106 Biol. Psychiatry 64, 835-841
-
(2008)
Biol. Psychiatry
, vol.64
, pp. 835-841
-
-
Yasuno, F.1
Ota, M.2
Kosaka, J.3
Ito, H.4
Higuchi, M.5
Doronbekov, T.K.6
Nozaki, S.7
Fujimura, Y.8
Koeda, M.9
Asada, T.10
Suhara, T.11
-
41
-
-
70349386259
-
Radiolabelled molecules for imaging the Translocator protein (18 kDa) using positron emission tomography
-
Dollé, F., Luus, C., Reynolds, A., and Kassiou, M. (2009) Radiolabelled molecules for imaging the Translocator protein (18 kDa) using positron emission tomography Curr. Med. Chem. 16, 2899-2923
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 2899-2923
-
-
Dollé, F.1
Luus, C.2
Reynolds, A.3
Kassiou, M.4
-
42
-
-
40749090848
-
11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors
-
DOI 10.1016/j.nucmedbio.2007.12.005, PII S0969805108000036
-
Sekimata, K., Hatano, K., Ogawa, M., Abe, J., Magata, Y., Biggio, G., Serra, M., Laquintana, V., Denora, N., Latrofa, A., Trapani, G., Liso, G., and Ito, K. (2008) Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors Nucl. Med. Biol. 35, 327-334 (Pubitemid 351381968)
-
(2008)
Nuclear Medicine and Biology
, vol.35
, Issue.3
, pp. 327-334
-
-
Sekimata, K.1
Hatano, K.2
Ogawa, M.3
Abe, J.4
Magata, Y.5
Biggio, G.6
Serra, M.7
Laquintana, V.8
Denora, N.9
Latrofa, A.10
Trapani, G.11
Liso, G.12
Ito, K.13
-
43
-
-
68249150559
-
Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand in humans
-
Endres, C. J., Pomper, M. G., James, M., Uzuner, O., Hammoud, D. A., Watkins, C. C., Reynolds, A., Hilton, J., Dannals, R. F., and Kassiou, M. (2009) Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand in humans J. Nucl. Med. 50, 1276-1282
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 1276-1282
-
-
Endres, C.J.1
Pomper, M.G.2
James, M.3
Uzuner, O.4
Hammoud, D.A.5
Watkins, C.C.6
Reynolds, A.7
Hilton, J.8
Dannals, R.F.9
Kassiou, M.10
-
44
-
-
77957967999
-
Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity
-
Yui, J., Hatori, A., Kawamura, K., Yanamoto, K., Yamasaki, T., Ogawa, M., Yoshida, Y., Kumata, K., Fujinaga, M., Nengaki, N., Fukumura, T., Suzuki, K., and Zhang, M. R. (2011) Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity Neuroimage 54, 123-130
-
(2011)
Neuroimage
, vol.54
, pp. 123-130
-
-
Yui, J.1
Hatori, A.2
Kawamura, K.3
Yanamoto, K.4
Yamasaki, T.5
Ogawa, M.6
Yoshida, Y.7
Kumata, K.8
Fujinaga, M.9
Nengaki, N.10
Fukumura, T.11
Suzuki, K.12
Zhang, M.R.13
-
45
-
-
77952904198
-
Imaging of the translocator protein (18 kDa) in rat brain after ischemia using [11C]DAC with ultra-high specific activity
-
Yui, J., Hatori, A., Yanamoto, K., Takei, M., Nengaki, N., Kumata, K., Kawamura, K., Yamasaki, T., Suzuki, K., and Zhang, M. R. (2010) Imaging of the translocator protein (18 kDa) in rat brain after ischemia using [11C]DAC with ultra-high specific activity Synapse 64, 488-493
-
(2010)
Synapse
, vol.64
, pp. 488-493
-
-
Yui, J.1
Hatori, A.2
Yanamoto, K.3
Takei, M.4
Nengaki, N.5
Kumata, K.6
Kawamura, K.7
Yamasaki, T.8
Suzuki, K.9
Zhang, M.R.10
-
46
-
-
79953004994
-
In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders
-
Maeda, J., Zhang, M. R., Okauchi, T., Ji, B., Ono, M., Hattori, S., Kumata, K., Iwata, N., Saido, T. C., Trojanowski, J. Q., Lee, V. M., Staufenbiel, M., Tomiyama, T., Mori, H., Fukumura, T., Suhara, T., and Higuchi, M. (2011) In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders J. Neurosci. 31, 4720-4730
-
(2011)
J. Neurosci.
, vol.31
, pp. 4720-4730
-
-
Maeda, J.1
Zhang, M.R.2
Okauchi, T.3
Ji, B.4
Ono, M.5
Hattori, S.6
Kumata, K.7
Iwata, N.8
Saido, T.C.9
Trojanowski, J.Q.10
Lee, V.M.11
Staufenbiel, M.12
Tomiyama, T.13
Mori, H.14
Fukumura, T.15
Suhara, T.16
Higuchi, M.17
-
47
-
-
79551569584
-
Comparison of 18F- and 11C-labeled aryloxyanilide analogs to measure translocator protein in humans brain using positron emission tomography
-
Dickstein, L. P., Zoghbi, S. S., Fujimura, Y., Imaizumi, M., Zhang, Y., Pike, V. W., Innis, R. B., and Fujita, M. (2011) Comparison of 18F- and 11C-labeled aryloxyanilide analogs to measure translocator protein in humans brain using positron emission tomography Eur. J. Nucl. Med. Mol. Imaging 38, 352-357
-
(2011)
Eur. J. Nucl. Med. Mol. Imaging
, vol.38
, pp. 352-357
-
-
Dickstein, L.P.1
Zoghbi, S.S.2
Fujimura, Y.3
Imaizumi, M.4
Zhang, Y.5
Pike, V.W.6
Innis, R.B.7
Fujita, M.8
-
48
-
-
79960997910
-
Quantitation of translocator protein binding in humans brain with the novel radioligand [18F]-FEPPA and positron emission tomography
-
Rusjan, P. M., Wilson, A. A., Bloomfield, P. M., Vitcu, I., Meyer, J. H., Houle, S., and Mizrahi, R. (2011) Quantitation of translocator protein binding in humans brain with the novel radioligand [18F]-FEPPA and positron emission tomography J. Cereb. Blood Flow Metab. 31, 1807-1816
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 1807-1816
-
-
Rusjan, P.M.1
Wilson, A.A.2
Bloomfield, P.M.3
Vitcu, I.4
Meyer, J.H.5
Houle, S.6
Mizrahi, R.7
-
49
-
-
84863022896
-
Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-1 8F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a] pyrimidin-3-yl)acetamide
-
Tang, D., Hight, M. R., McKinley, E. T., Fu, A., Buck, J. R., Smith, R. A., Tantawy, M. N., Peterson, T. E., Colvin, D. C., Ansari, M. S., Nickels, M., and Manning, H. C. (2012) Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-1 8F-fluoroethoxy)phenyl)-5,7- dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide J. Nucl. Med. 53, 287-294
-
(2012)
J. Nucl. Med.
, vol.53
, pp. 287-294
-
-
Tang, D.1
Hight, M.R.2
McKinley, E.T.3
Fu, A.4
Buck, J.R.5
Smith, R.A.6
Tantawy, M.N.7
Peterson, T.E.8
Colvin, D.C.9
Ansari, M.S.10
Nickels, M.11
Manning, H.C.12
-
50
-
-
84860337119
-
Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation
-
Arlicot, N., Vercouillie, J., Ribeiro, M. J., Tauber, C., Venel, Y., Baulieu, J. L., Maia, S., Corcia, P., Stabin, M. G., Reynolds, A., Kassiou, M., and Guilloteau, D. (2012) Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation Nucl. Med. Biol. 39, 570-578
-
(2012)
Nucl. Med. Biol.
, vol.39
, pp. 570-578
-
-
Arlicot, N.1
Vercouillie, J.2
Ribeiro, M.J.3
Tauber, C.4
Venel, Y.5
Baulieu, J.L.6
Maia, S.7
Corcia, P.8
Stabin, M.G.9
Reynolds, A.10
Kassiou, M.11
Guilloteau, D.12
-
51
-
-
77952093172
-
In vivo imaging of neuroinflammation: A comparative study between [(18)F]PBR111, [(11)C]CLINME and [(11)C]PK11195 in an acute rodent model
-
Van, C. N., Boisgard, R., Kuhnast, B., Theze, B., Viel, T., Gregoire, M. C., Chauveau, F., Boutin, H., Katsifis, A., Dollé, F., and Tavitian, B. (2010) In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [(11)C]CLINME and [(11)C]PK11195 in an acute rodent model Eur. J. Nucl. Med. Mol. Imaging 37, 962-972
-
(2010)
Eur. J. Nucl. Med. Mol. Imaging
, vol.37
, pp. 962-972
-
-
Van, C.N.1
Boisgard, R.2
Kuhnast, B.3
Theze, B.4
Viel, T.5
Gregoire, M.C.6
Chauveau, F.7
Boutin, H.8
Katsifis, A.9
Dollé, F.10
Tavitian, B.11
-
52
-
-
84855354847
-
18F] FEDAA1106 - Selective radioligands for imaging TSPO18 kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls
-
18F]FEDAA1106- Selective radioligands for imaging TSPO18 kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls Appl. Radiat. Isot. 70, 489-497
-
(2012)
Appl. Radiat. Isot.
, vol.70
, pp. 489-497
-
-
Kuhnast, B.1
Damont, A.2
Hinnen, F.3
Catarina, T.4
Demphel, S.5
Le Helleix, S.6
Coulon, C.7
Goutal, S.8
Gervais, P.9
Dollé, F.10
-
53
-
-
70349645989
-
A biomathematical modeling approach to central nervous system radioligand discovery and development
-
Guo, Q., Brady, M., and Gunn, R. N. (2009) A biomathematical modeling approach to central nervous system radioligand discovery and development J. Nucl. Med. 50, 1715-1723
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 1715-1723
-
-
Guo, Q.1
Brady, M.2
Gunn, R.N.3
-
55
-
-
0033059817
-
Calculation of positron range and its effect on the fundamental limit of positron emission tomography system spatial resolution
-
DOI 10.1088/0031-9155/44/3/019, PII S0031915599950285
-
Levin, C. S. and Hoffman, E. J. (1999) Calculation of positron range and its effect on the fundamental limit of positron emission tomography system spatial resolution Phys. Med. Biol. 44, 781-799 (Pubitemid 29133069)
-
(1999)
Physics in Medicine and Biology
, vol.44
, Issue.3
, pp. 781-799
-
-
Levin, C.S.1
Hoffman, E.J.2
-
56
-
-
59349100522
-
Non-invasive visualization of CNS inflammation with nuclear and optical imaging
-
Wunder, A., Klohs, J., and Dirnagl, U. (2009) Non-invasive visualization of CNS inflammation with nuclear and optical imaging Neuroscience 158, 1161-1173
-
(2009)
Neuroscience
, vol.158
, pp. 1161-1173
-
-
Wunder, A.1
Klohs, J.2
Dirnagl, U.3
-
58
-
-
75149168815
-
Near-infrared fluorescence: Application to in vivo molecular imaging
-
Hilderbrand, S. A. and Weissleder, R. (2010) Near-infrared fluorescence: application to in vivo molecular imaging Curr. Opin. Chem. Biol. 14, 71-79
-
(2010)
Curr. Opin. Chem. Biol.
, vol.14
, pp. 71-79
-
-
Hilderbrand, S.A.1
Weissleder, R.2
-
59
-
-
0030739178
-
Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: A fluorescent probe for the peripheral-type benzodiazepine receptor
-
DOI 10.1021/jm970220w
-
Kozikowski, A. P., Kotoula, M., Ma, D., Boujrad, N., Tuckmantel, W., and Papadopoulos, V. (1997) Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol- 4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor J. Med. Chem. 40, 2435-2439 (Pubitemid 27347006)
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, Issue.16
, pp. 2435-2439
-
-
Kozikowski, A.P.1
Kotoula, M.2
Ma, D.3
Boujrad, N.4
Tuckmantel, W.5
Papadopoulos, V.6
-
60
-
-
20144378663
-
Methyl pyropheophorbide-a analogues: Potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy
-
DOI 10.1021/jm050039k
-
Chen, Y., Zheng, X., Dobhal, M. P., Gryshuk, A., Morgan, J., Dougherty, T. J., Oseroff, A., and Pandey, R. K. (2005) Methyl pyrophorbide-R analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy J. Med. Chem. 48, 3692-3695 (Pubitemid 40776843)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.11
, pp. 3692-3695
-
-
Chen, Y.1
Zheng, X.2
Dobhal, M.P.3
Gryshuk, A.4
Morgan, J.5
Dougherty, T.J.6
Oseroff, A.7
Pandey, R.K.8
-
61
-
-
0037018442
-
Facile efficient conjugation of a trifunctional lanthanide chelate to a peripheral benzodiazepine receptor ligand
-
Manning, H. C., Goebel, T., Marx, J. N., and Bornhop, D. J. (2002) Facile efficient conjugation of a trifunctional lanthanide chelate to a peripheral benzodiazepine receptor ligand Org. Lett. 4, 1075-1078
-
(2002)
Org. Lett.
, vol.4
, pp. 1075-1078
-
-
Manning, H.C.1
Goebel, T.2
Marx, J.N.3
Bornhop, D.J.4
-
62
-
-
9244255341
-
Targeted molecular imaging agents for cellular-scale bimodal imaging
-
DOI 10.1021/bc049904q
-
Manning, H. C., Goebel, T., Thompson, R. C., Price, R. R., Lee, H., and Bornhop, D. J. (2004) Targeted molecular imaging agents for cellular-scale bimodal imaging Bioconjugate Chem. 15, 1488-1495 (Pubitemid 39552041)
-
(2004)
Bioconjugate Chemistry
, vol.15
, Issue.6
, pp. 1488-1495
-
-
Manning, H.C.1
Goebel, T.2
Thompson, R.C.3
Price, R.R.4
Lee, H.5
Bornhop, D.J.6
-
63
-
-
33646936847
-
A peripheral benzodiazepine receptor targeted agent for in vitro imaging and screening
-
DOI 10.1021/bc060020b
-
Manning, H. C., Smith, S. M., Sexton, M., Haviland, S., Bai, M., Cederquist, K., Stella, N., and Bornhop, D. J. (2006) A peripheral benzodiazepine receptor targeted agent for in vitro imaging and screening Bioconjugate Chem. 17, 735-740 (Pubitemid 43794384)
-
(2006)
Bioconjugate Chemistry
, vol.17
, Issue.3
, pp. 735-740
-
-
Manning, H.C.1
Smith, S.M.2
Sexton, M.3
Haviland, S.4
Bai, M.5
Cederquist, K.6
Stella, N.7
Bornhop, D.J.8
-
64
-
-
34547162879
-
A novel conjugable translocator protein ligand labeled with a fluorescence dye for in vitro imaging
-
DOI 10.1021/bc060381r
-
Bai, M., Wyatt, S., Han, Z., Papadopoulos, V., and Bornhop, D. J. (2007) A novel conjugable translocator protein ligand with a fluorescent dye for in vitro imaging Bioconjugate Chem. 18, 1118-1122 (Pubitemid 47122632)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.4
, pp. 1118-1122
-
-
Bai, M.1
Wyatt, S.K.2
Han, Z.3
Papadopoulos, V.4
Bornhop, D.J.5
-
65
-
-
36849082612
-
A novel functional translocator protein ligand for cancer imaging
-
DOI 10.1021/bc700251e
-
Bai, M., Rone, M. B., Papadopoulos, V., and Bornhop, D. J. (2007) A novel functional translocator protein ligand for cancer imaging Bioconjugate Chem. 18, 2018-2023 (Pubitemid 350220003)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.6
, pp. 2018-2023
-
-
Bai, M.1
Rone, M.B.2
Papadopoulos, V.3
Bornhop, D.J.4
-
66
-
-
77956671187
-
Molecular imaging of the Translocator Protein (TSPO) in a pre-clinical model of breast cancer
-
Wyatt, S. K., Manning, H. C., Bai, M., Bailey, S. N., Gallant, P., Ma, G., McIntosh, L., and Bornhop, D. J. (2010) Molecular imaging of the Translocator Protein (TSPO) in a pre-clinical model of breast cancer Mol. Imaging Biol. 12, 349-358
-
(2010)
Mol. Imaging Biol.
, vol.12
, pp. 349-358
-
-
Wyatt, S.K.1
Manning, H.C.2
Bai, M.3
Bailey, S.N.4
Gallant, P.5
Ma, G.6
McIntosh, L.7
Bornhop, D.J.8
-
67
-
-
84875485383
-
Confounding parameters in preclinical assessment of Blood-Brain Barrier permeation: An overview with emphasis on species differences and effect of disease states
-
Deo, A. K, Theil, F. P., and Nicolas, J. M. (2013) Confounding parameters in preclinical assessment of Blood-Brain Barrier permeation: an overview with emphasis on species differences and effect of disease states Mol. Pharmaceutics 10, 1581-1595
-
(2013)
Mol. Pharmaceutics
, vol.10
, pp. 1581-1595
-
-
Deo, A.K.1
Theil, F.P.2
Nicolas, J.M.3
-
68
-
-
63349090588
-
Recent advances in medicinal chemistry- and pharmaceutical technology-strategies for drug delivery to the brain
-
Denora, N., Trapani, A., Laquintana, V., Lopedota, A., and Trapani, G. (2009) Recent advances in medicinal chemistry- and pharmaceutical technology-strategies for drug delivery to the brain Curr. Top. Med. Chem. 9, 182-196
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 182-196
-
-
Denora, N.1
Trapani, A.2
Laquintana, V.3
Lopedota, A.4
Trapani, G.5
-
69
-
-
19944429835
-
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands
-
DOI 10.1021/jm049610q
-
Trapani, G., Laquintana, V., Denora, N., Trapani, A., Lopedota, A., Latrofa, A., Franco, M., Serra, M., Pisu, M. G., Floris, I., Sanna, E., Biggio, G., and Liso, G. (2005) Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a] pyridineacetamide peripheral benzodiazepine receptors ligands J. Med. Chem. 48, 292-305 (Pubitemid 40105268)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.1
, pp. 292-305
-
-
Trapani, G.1
Laquintana, V.2
Denora, N.3
Trapani, A.4
Lopedota, A.5
Latrofa, A.6
Franco, M.7
Serra, M.8
Pisu, M.G.9
Floris, I.10
Sanna, E.11
Biggio, G.12
Liso, G.13
-
70
-
-
34648840352
-
N-benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl) -N-(6-(7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino)hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization
-
DOI 10.1021/bc060393c
-
Laquintana, V., Denora, N., Lopedota, A., Suzuki, H., Sawada, M., Serra, M., Biggio, G., Latrofa, A., Trapani, G., and Liso, G. (2007) N -Benzyl-2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a] pyridin-3-yl)-N-(6- (7-nitrobenzo[c][1,2,5]oxadiazol-4-ylamino) hexyl)acetamide as a new fluorescent probe for peripheral benzodiazepine receptor and microglial cell visualization Bioconjugate Chem. 18, 1397-1407 (Pubitemid 47464046)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.5
, pp. 1397-1407
-
-
Laquintana, V.1
Denora, N.2
Lopedota, A.3
Suzuki, H.4
Sawada, M.5
Serra, M.6
Biggio, G.7
Latrofa, A.8
Trapani, G.9
Liso, G.10
-
71
-
-
0032811868
-
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration
-
DOI 10.1021/js980402t
-
Clark, D. E. (1999) Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration J. Pharm. Sci. 88, 815-821 (Pubitemid 29398551)
-
(1999)
Journal of Pharmaceutical Sciences
, vol.88
, Issue.8
, pp. 815-821
-
-
Clark, D.E.1
-
72
-
-
56249143493
-
2-Phenyl-imidazo[1,2-a]pyridine compounds containing hydrophilic groups as potent and selective ligands for peripheral benzodiazepine receptors: Synthesis, binding affinity and electrophysiological studies
-
Denora, N., Laquintana, V., Pisu, M. G., Dore, R., Murru, L., Latrofa, A., Trapani, G., and Sanna, E. (2008) 2-Phenyl-imidazo[1,2-a]pyridine compounds containing hydrophilic groups as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity and electrophysiological studies J. Med. Chem. 51, 6876-88
-
(2008)
J. Med. Chem.
, vol.51
, pp. 6876-6888
-
-
Denora, N.1
Laquintana, V.2
Pisu, M.G.3
Dore, R.4
Murru, L.5
Latrofa, A.6
Trapani, G.7
Sanna, E.8
-
73
-
-
84856228766
-
New fluorescent probes targeting the mitochondrial-located translocator protein 18 kDa (TSPO) as activated microglia imaging agents
-
Denora, N., Laquintana, N., Trapani, A., Suzuki, H., Sawada, M., and Trapani, G. (2011) New fluorescent probes targeting the mitochondrial-located translocator protein 18 kDa (TSPO) as activated microglia imaging agents Pharm. Res. 28, 2820-2832
-
(2011)
Pharm. Res.
, vol.28
, pp. 2820-2832
-
-
Denora, N.1
Laquintana, N.2
Trapani, A.3
Suzuki, H.4
Sawada, M.5
Trapani, G.6
-
74
-
-
33846442037
-
New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: Design, synthesis, and biological evaluation
-
DOI 10.1021/jm061137o
-
Taliani, S., Simorini, F., Sergianni, V., La Motta, C., Da Settimo, F., Cosimelli, B., Abignente, E., Greco, G., Novellino, E., Rossi, L., Gremigni, V., Spinetti, F., Chelli, B., and Martini, C. (2007) New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation J. Med. Chem. 50, 404-407 (Pubitemid 46147722)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.2
, pp. 404-407
-
-
Taliani, S.1
Simorini, F.2
Sergianni, V.3
La Motta, C.4
Da Settimo, F.5
Cosimelli, B.6
Abignente, E.7
Greco, G.8
Novellino, E.9
Rossi, L.10
Gremigni, V.11
Spinetti, F.12
Chelli, B.13
Martini, C.14
-
75
-
-
77952710965
-
Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: Synthesis and biological characterization
-
Taliani, S., Da Pozzo, E., Bellandi, M., Bendinelli, S., Pugliesi, I., Simorini, F., La Motta, C., Salerno, S., Marini, A. M., Da Settimo, F., Cosimelli, B., Greco, G., Novellino, E., and Martini, C. (2010) Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: synthesis and biological characterization J. Med. Chem. 53, 4085-4093
-
(2010)
J. Med. Chem.
, vol.53
, pp. 4085-4093
-
-
Taliani, S.1
Da Pozzo, E.2
Bellandi, M.3
Bendinelli, S.4
Pugliesi, I.5
Simorini, F.6
La Motta, C.7
Salerno, S.8
Marini, A.M.9
Da Settimo, F.10
Cosimelli, B.11
Greco, G.12
Novellino, E.13
Martini, C.14
-
76
-
-
71649107843
-
In vivo, in vitro and in silico methods for small molecule transfer across the BBB
-
Mensch, J., Oyarzabal, J., Mackie, C., and Augustijns, P. (2009) In vivo, in vitro and in silico methods for small molecule transfer across the BBB J. Pharm. Sci. 98, 4429-4468
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 4429-4468
-
-
Mensch, J.1
Oyarzabal, J.2
Mackie, C.3
Augustijns, P.4
-
77
-
-
71249088415
-
TSPO targeted dendrimer imaging agent: Synthesis, characterization and cellular internalization
-
Samuelson, L. E., Dukes, M. J., Hunt, C. R., Casey, J. D., and Bornhop, D. J. (2009) TSPO targeted dendrimer imaging agent: synthesis, characterization and cellular internalization Bioconjugate Chem. 20, 2082-2089
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 2082-2089
-
-
Samuelson, L.E.1
Dukes, M.J.2
Hunt, C.R.3
Casey, J.D.4
Bornhop, D.J.5
-
78
-
-
78649968090
-
Nanotheranostics and image-guided drug delivery: Current concepts and future directions
-
Lammers, T., Kiessling, F., Hennink, W. E., and Storm, G. (2010) Nanotheranostics and image-guided drug delivery: current concepts and future directions Mol. Pharmaceutics 7, 1899-1912
-
(2010)
Mol. Pharmaceutics
, vol.7
, pp. 1899-1912
-
-
Lammers, T.1
Kiessling, F.2
Hennink, W.E.3
Storm, G.4
-
79
-
-
78649924497
-
Targeted imaging and therapy of brain cancer using theranostic nanoparticles
-
Bhojani, M. S., Van Dort, M., Rehemtulla, A., and Ross, B. D. (2010) Targeted imaging and therapy of brain cancer using theranostic nanoparticles Mol. Pharmaceutics 7, 1921-1929
-
(2010)
Mol. Pharmaceutics
, vol.7
, pp. 1921-1929
-
-
Bhojani, M.S.1
Van Dort, M.2
Rehemtulla, A.3
Ross, B.D.4
-
80
-
-
84870429669
-
Dendrimers as vectors for genetic material delivery to the Nervous System
-
Perez-Martinez, F. C., Ocaña, A. V., Perez-Carrion, M. D., and Ceña, V. (2012) Dendrimers as vectors for genetic material delivery to the Nervous System Curr. Med. Chem. 19, 5101-5108
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 5101-5108
-
-
Perez-Martinez, F.C.1
Ocaña, A.V.2
Perez-Carrion, M.D.3
Ceña, V.4
-
81
-
-
39749086433
-
Polymeric nanoparticles for the drug delivery to the central nervous system
-
DOI 10.1517/17425247.5.2.155
-
Tosi, G., Costantino, L., Ruozi, B., Forni, F., and Vandelli, M. A. (2008) Polymeric nanoparticles for the drug delivery to the central nervous system Expert Opin. Drug Delivery 5, 155-174 (Pubitemid 351308309)
-
(2008)
Expert Opinion on Drug Delivery
, vol.5
, Issue.2
, pp. 155-174
-
-
Tosi, G.1
Costantino, L.2
Ruozi, B.3
Forni, F.4
Vandelli, M.A.5
-
82
-
-
68649090916
-
Nanoparticles for direct nose-to-brain delivery of drugs
-
Mistry, A., Stolnik, S., and Illum, L. (2009) Nanoparticles for direct nose-to-brain delivery of drugs Int. J. Pharm. 379, 146-157
-
(2009)
Int. J. Pharm.
, vol.379
, pp. 146-157
-
-
Mistry, A.1
Stolnik, S.2
Illum, L.3
-
83
-
-
34547871312
-
Solid lipid nanoparticles for targeted brain drug delivery
-
DOI 10.1016/j.addr.2007.04.011, PII S0169409X07000427, Lipid Nanoparticles: Recent Advances
-
Blasi, P., Giovagnoli, S., Schoubben, A., Ricci, M., and Rossi, C. (2007) Solid lipid nanoparticles for targeted brain drug delivery Adv. Drug Delivery Rev. 59, 454-477 (Pubitemid 47259226)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.6
, pp. 454-477
-
-
Blasi, P.1
Giovagnoli, S.2
Schoubben, A.3
Ricci, M.4
Rossi, C.5
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