In vivo imaging of neuroinflammation: A comparative study between [ 18F]PBR111, [11C]CLINME and [11C]PK11195 in an acute rodent model

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 37, Issue 5, 2010, Pages 962-972

  Van Camp, Nadja ^a,b,c   Boisgard, Raphael ^a,b   Kuhnast, Bertrand ^a   Thézé, Benoit ^a,b   Viel, Thomas ^a,b   Grégoire, Marie Claude ^d   Chauveau, Fabien ^a,b,e   Boutin, Hervé ^f   Katsifis, Andrew ^d   Dollé, Frédéric ^a   Tavitian, Bertrand ^a,b  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b INSERM   (France)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^e UNIVERSITÉ DE LYON   (France)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

CLINME; Neuroinflammation; PBR; PBR111; PET; PK11195; Rat; TSPO

Indexed keywords

2 [6 CHLORO 2 (4 IODOPHENYL) IMIDAZO[1,2 A]PYRIDIN 3 YL] N ETHYL N METHYLACETAMIDE C 11; 2 [6 CHLORO 2 [4 (3 FLUOROPROPOXY)PHENYL]IMIDAZO[1,2 A]PYRIDIN 3 YL] N,N DIETHYLACETAMIDE F 18; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; CELL DENSITY; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGE ANALYSIS; IMAGING; IMMUNOHISTOCHEMISTRY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT;

ACETAMIDES; AMIDES; ANIMALS; AUTORADIOGRAPHY; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM DISEASES; DISEASE MODELS, ANIMAL; FLUORINE RADIOISOTOPES; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; ISOQUINOLINES; LIGANDS; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, GABA-A;

EID: 77952093172     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-009-1353-0     Document Type: Article

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