New fluorescent probes targeting the mitochondrial- located Translocator protein 18 kDa (TSPO) as activated microglia imaging agents

Pharmaceutical Research

Volumn 28, Issue 11, 2011, Pages 2820-2832

  Denora, Nunzio ^a   Laquintana, Valentino ^a   Trapani, Adriana ^a   Suzuki, Hiromi ^b   Sawada, Makoto ^b   Trapani, Giuseppe ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Activated microglia imaging; Fluorescence microscopy; Imidazopyridine compounds; TSPO

Indexed keywords

CARRIER PROTEIN; CD11B ANTIGEN; FLUORESCENT DYE; IMIDAZOPYRIDINE DERIVATIVE; LIPOPOLYSACCHARIDE; TRANSLOCATOR PROTEIN 18; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN INJURY; CELL ACTIVATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; HISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROGLIA; MITOCHONDRIAL TARGETING SIGNAL; MOLECULAR IMAGING; MOLECULAR PROBE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS; PROTEIN TARGETING; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN; DRUG ADMINISTRATION ROUTES; DRUG STABILITY; FEMALE; FLUORESCENT DYES; ISOQUINOLINES; LIGANDS; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; MITOCHONDRIAL PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, GABA;

EID: 84856228766     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0552-0     Document Type: Article

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