Radiolabelled molecules for imaging the translocator protein (18 kDa) using positron emission tomography

Current Medicinal Chemistry

Volumn 16, Issue 22, 2009, Pages 2899-2923

  Dollé, Frédéric ^a   Luus, Christopher ^b,c   Reynolds, Aaron ^c,d   Kassiou, Michael ^c,d  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b University of Sydney   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Carbon 11; Fluorine 18; Ligand; Microglia; Neuroinflammation; Peripheral benzodiazepine receptor; Positron emission tomography; Translocator protein

Indexed keywords

2 ARYL 8 OXODIHYDROPURINE DERIVATIVE; 2 PHENYLIMIDAZO [1,2 BETA] PYRIMIDIN 3 YL ACETAMIDE C 11; 2 PHENYLPYRAZOLO [1,5 ALPHA] PYRIMIDIN 3 YL ACETAMIDE C 11; BENZODIAZEPINE 4' CHLORODIAZEPAM; BENZODIAZEPINE 4' CHLORODIAZEPAM C 11; BENZODIAZEPINE RECEPTOR; CARBON 11; FLUORINE 18; FLUORODEOXYGLUCOSE F 18; FLUOROIODOMETHANE F 18; FMDAA 1006; IMIDAZO [1,2 ALPHA] PYRIDIN 3 YL ACETAMIDE DERIVATIVE C 11; ISOQUINOLINE 3 CARBOXAMIDE C 11; METHYL IODIDE C 11; METHYL TRIFLATE C 11; N BENZYL N (2 PHENOXYARYL)ACETAMIDE C 11; N BENZYL N (2 PHENOXYPHENYL)ACETAMIDE C 11; N BENZYL N (2 PHENOXYPHENYL)ACETAMIDE F 18; N BENZYL N (2 PHENOXYPYRIDIN 3 YL)ACETAMIDE C 11; N BENZYL N (2 PHENOXYPYRIDIN 3 YL)ACETAMIDE F 18; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; N SEC BUTYL 1 (2 FLUORO 5 NITROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N SEC BUTYL 1 (2 FLUORO 5 NITROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; OXYGEN 15; PERIPHERAL BENZODIAZEPINE RECEPTOR; PK 11211; QUINOLINE 2 CARBOXAMIDE C 11; RADIOPHARMACEUTICAL AGENT; RO 54864; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINPOCETINE C 11;

BINDING AFFINITY; CELL ACTIVATION; CHEMICAL STRUCTURE; DRUG DESIGN; DRUG HALF LIFE; DRUG SYNTHESIS; DRUG UPTAKE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUNTINGTON CHOREA; IMAGE ANALYSIS; IMAGE QUALITY; ISOTOPE LABELING; MICROGLIA; MOLECULAR IMAGING; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVIEW; SYNTHESIS;

BRAIN; HUMANS; MICROGLIA; MOLECULAR STRUCTURE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, GABA;

EID: 70349386259     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709788803150     Document Type: Review

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