IGF-IR signaling attenuates the age-related decline of diastolic cardiac function

American Journal of Physiology - Endocrinology and Metabolism

Volumn 303, Issue 2, 2012, Pages

  Moellendorf, Sarah ^a   Kessels, Claudia ^a   Peiseler, Lena ^a   Raupach, Annika ^a   Jacoby, Christoph ^a   Vogt, Nora ^a   Lindecke, Antje ^b   Koch, Linda ^c   Brüning, Jens ^c   Heger, Jacqueline ^d   Köhrer, Karl ^b   Gödecke, Axel ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Akt; Diabetes; Heart; Insulin like growth factor I receptor

Indexed keywords

AFIMOXIFENE; CRE RECOMBINASE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; PROTEIN KINASE B; SOMATOMEDIN C RECEPTOR; STREPTOZOCIN;

AGE DISTRIBUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIASTOLE; EMBRYO DEVELOPMENT; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HEART FUNCTION; HEART MUSCLE CELL; MANOMETRY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION PROFILING; GLYCOGEN SYNTHASE KINASE 3; HEART; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION;

EID: 84863966855     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00538.2011     Document Type: Article

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