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Volumn 90, Issue 15-16, 2012, Pages 619-628

Effect of persistent activation of phosphoinositide 3-kinase on heart

Author keywords

Aging; Gene expression; Insulin; Phosphoinositide 3 kinase

Indexed keywords

BETA GALACTOSIDASE; CHAPERONE; CYTOKINE; INSULIN RECEPTOR SUBSTRATE 2; LIPOFUSCIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAPAMYCIN; SOMATOMEDIN C; TENSIN; TRANSCRIPTION FACTOR FKHR;

EID: 84859722267     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.02.010     Document Type: Article
Times cited : (8)

References (42)
  • 2
    • 33645971014 scopus 로고    scopus 로고
    • 2 + signalling systems and cardiac hypertrophy
    • 2 + signalling systems and cardiac hypertrophy Biochem Soc Trans 34 2006 228 231
    • (2006) Biochem Soc Trans , vol.34 , pp. 228-231
    • Berridge, M.J.1
  • 3
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • DOI 10.1126/science.296.5573.1655
    • L.C. Cantley The phosphoinositide 3-kinase pathway Science 296 2002 1655 1657 (Pubitemid 34579158)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1655-1657
    • Cantley, L.C.1
  • 4
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-β levels
    • DOI 10.1038/nm793
    • E. Carro, J.L. Trejo, T. Gomez-Isia, D. LeRoith, and I. Torres-Aleman Serum insulin-like growth factor 1 regulates brain amyloid-beta levels Nat Med 8 2002 1390 1397 (Pubitemid 36019424)
    • (2002) Nature Medicine , vol.8 , Issue.12 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 6
    • 52449086907 scopus 로고    scopus 로고
    • The insulin paradox: Aging, proteotoxicity and neurodegeneration
    • E. Cohen, and A. Dillin The insulin paradox: aging, proteotoxicity and neurodegeneration Nat Rev Neurosci 9 2008 759 767
    • (2008) Nat Rev Neurosci , vol.9 , pp. 759-767
    • Cohen, E.1    Dillin, A.2
  • 7
    • 71449108913 scopus 로고    scopus 로고
    • Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
    • E. Cohen, J.F. Paulsson, P. Blinder, T. Burstyn-Cohen, D. Du, and G. Estepa Reduced IGF-1 signaling delays age-associated proteotoxicity in mice Cell 139 2009 1157 1169
    • (2009) Cell , vol.139 , pp. 1157-1169
    • Cohen, E.1    Paulsson, J.F.2    Blinder, P.3    Burstyn-Cohen, T.4    Du, D.5    Estepa, G.6
  • 8
    • 38449106570 scopus 로고    scopus 로고
    • FOXO transcription factors in the regulatory networks of longevity
    • DOI 10.1093/jb/mvm104
    • H. Daitoku, and A. Fukamizu FOXO transcription factors in the regulatory networks of longevity J Biochem 141 2007 769 774 (Pubitemid 351455333)
    • (2007) Journal of Biochemistry , vol.141 , Issue.6 , pp. 769-774
    • Daitoku, H.1    Fukamizu, A.2
  • 9
    • 0033228631 scopus 로고    scopus 로고
    • N-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice
    • M.C. Delaughter, G.E. Taffet, M.L. Fiorotto, M.L. Entman, and R.J. Schwartz Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice FASEB J 13 1999 1923 1929 (Pubitemid 29517622)
    • (1999) FASEB Journal , vol.13 , Issue.14 , pp. 1923-1929
    • Delaughter, M.C.1    Taffet, G.E.2    Fiorotto, M.L.3    Entman, M.L.4    Schwartz, R.J.5
  • 10
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • C. Deng, P. Zhang, J.W. Harper, S.J. Elledge, and P. Leder Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control Cell 25 82 1995 675 684
    • (1995) Cell , vol.25 , Issue.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 11
    • 0033553415 scopus 로고    scopus 로고
    • Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance
    • K. Egawa, P.M. Sharma, N. Nakashima, Y. Huang, E. Huver, and G.R. Boss Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance J Biol Chem 274 1999 14306 14314
    • (1999) J Biol Chem , vol.274 , pp. 14306-14314
    • Egawa, K.1    Sharma, P.M.2    Nakashima, N.3    Huang, Y.4    Huver, E.5    Boss, G.R.6
  • 12
    • 0034455290 scopus 로고    scopus 로고
    • Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes
    • DOI 10.1210/en.141.6.1930
    • K. Egawa, N. Nakashima, P.M. Sharma, H. Maegawa, Y. Nagai, and A. Kashiwagi Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes Endocrinology 141 2000 1930 1935 (Pubitemid 32274339)
    • (2000) Endocrinology , vol.141 , Issue.6 , pp. 1930-1935
    • Egawa, K.1    Nakashima, N.2    Sharma, P.M.3    Maegawa, H.4    Nagai, Y.5    Kashiwagi, A.6    Kikkawa, R.7    Olefsky, J.M.8
  • 13
    • 66149102890 scopus 로고    scopus 로고
    • The role of FOXO in the regulation of metabolism
    • D.N. Gross, M. Wan, and M.J. Birnbaum The role of FOXO in the regulation of metabolism Curr Diab Rep 9 2009 208 214
    • (2009) Curr Diab Rep , vol.9 , pp. 208-214
    • Gross, D.N.1    Wan, M.2    Birnbaum, M.J.3
  • 15
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • DOI 10.1101/gad.1212704
    • N. Hay, and N. Sonenberg Upstream and downstream of mTOR Genes Dev 18 2004 1926 1945 (Pubitemid 39071573)
    • (2004) Genes and Development , vol.18 , Issue.16 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 16
    • 0038701745 scopus 로고    scopus 로고
    • Regulation of aging and age-related disease by DAF-16 and heat-shock factor
    • DOI 10.1126/science.1083701
    • A.L. Hsu, C.T. Murphy, and C. Kenyon Regulation of aging and age-related disease by DAF-16 and heat-shock factor Science 300 2003 1142 1145 (Pubitemid 36583098)
    • (2003) Science , vol.300 , Issue.5622 , pp. 1142-1145
    • Hsu, A.-L.1    Murphy, C.T.2    Kenyon, C.3
  • 17
    • 70350540920 scopus 로고    scopus 로고
    • Suppression of phosphoinositide 3kinase prevents cardiac aging in mice
    • Y. Inuzuka, J. Okuda, T. Kawashima, T. Kato, S. Niizuma, and Y. Tamaki Suppression of phosphoinositide 3kinase prevents cardiac aging in mice Circulation 120 2009 1695 1703
    • (2009) Circulation , vol.120 , pp. 1695-1703
    • Inuzuka, Y.1    Okuda, J.2    Kawashima, T.3    Kato, T.4    Niizuma, S.5    Tamaki, Y.6
  • 18
    • 0023713203 scopus 로고
    • Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload
    • S. Izumo, B. Nadal-Ginard, and V. Mahdavi Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload Proc Natl Acad Sci U S A 85 1988 339 343
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 339-343
    • Izumo, S.1    Nadal-Ginard, B.2    Mahdavi, V.3
  • 19
    • 77951985216 scopus 로고    scopus 로고
    • Examination of the expanding pathways for the regulation of p21 expression and activity
    • Y.S. Jung, Y. Qian, and X. Chen Examination of the expanding pathways for the regulation of p21 expression and activity Cell Signal 22 2010 1003 1012
    • (2010) Cell Signal , vol.22 , pp. 1003-1012
    • Jung, Y.S.1    Qian, Y.2    Chen, X.3
  • 20
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • DOI 10.1016/j.cell.2005.02.002
    • C. Kenyon The plasticity of aging: insights from long-lived mutants Cell 120 2005 449 460 (Pubitemid 40269760)
    • (2005) Cell , vol.120 , Issue.4 , pp. 449-460
    • Kenyon, C.1
  • 21
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • C. Kenyon The genetics of ageing Nature 464 2010 504 512
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.1
  • 22
    • 0027311858 scopus 로고
    • 1 progression
    • DOI 10.1016/0092-8674(93)90144-F
    • J. Kunz, R. Henriquez, U. Schneider, M. Deuter-Reinhard, N.R. Movva, and M.N. Hall Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression Cell 73 1993 585 596 (Pubitemid 23143356)
    • (1993) Cell , vol.73 , Issue.3 , pp. 585-596
    • Kunz, J.1    Henriquez, R.2    Schneider, U.3    Deuter-Reinhard, M.4    Movva, N.R.5    Hall, M.N.6
  • 26
    • 0028124189 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin
    • T. Okada, Y. Kawano, T. Sakakibara, O. Hazeki, and M. Ui Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin J Biol Chem 269 1994 3568 3573
    • (1994) J Biol Chem , vol.269 , pp. 3568-3573
    • Okada, T.1    Kawano, Y.2    Sakakibara, T.3    Hazeki, O.4    Ui, M.5
  • 28
    • 44649110104 scopus 로고    scopus 로고
    • Structural basis for the cooperation of hsp70 and hsp110 chaperones in protein folding
    • DOI 10.1016/j.cell.2008.05.022, PII S0092867408006788
    • S. Polier, Z. Dragovic, F.U. Hartl, and A. Bracher Structural basis for the cooperation of hsp70 and hsp110 chaperones in protein folding Cell 133 2008 1068 1079 (Pubitemid 351787748)
    • (2008) Cell , vol.133 , Issue.6 , pp. 1068-1079
    • Polier, S.1    Dragovic, Z.2    Hartl, F.U.3    Bracher, A.4
  • 29
    • 79960337702 scopus 로고    scopus 로고
    • Modelling the role of the hsp70/hsp90 system in the maintenance of protein homeostasis
    • C.J. Proctor, and I.A. Lorimer Modelling the role of the hsp70/hsp90 system in the maintenance of protein homeostasis PLoS One 6 2011 e22038
    • (2011) PLoS One , vol.6 , pp. 22038
    • Proctor, C.J.1    Lorimer, I.A.2
  • 30
    • 0037433040 scopus 로고    scopus 로고
    • Identifying differentially expressed genes using false discovery rate controlling procedures
    • DOI 10.1093/bioinformatics/btf877
    • A. Reiner, D. Yekutieli, and Y. Benjamini Identifying differentially expressed genes using false discovery rate controlling procedures Bioinformatics 19 2003 368 375 (Pubitemid 36284936)
    • (2003) Bioinformatics , vol.19 , Issue.3 , pp. 368-375
    • Reiner, A.1    Yekutieli, D.2    Benjamini, Y.3
  • 31
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • T. Schmelzle, and M.N. Hall TOR, a central controller of cell growth Cell 103 2000 253 262
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 32
    • 4544343980 scopus 로고    scopus 로고
    • Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
    • DOI 10.1016/j.cub.2004.08.026, PII S0960982204006116
    • O.J. Shah, Z. Wang, and T. Hunter Inappropriate activation of the tsc/rheb/mtor/s6k cassette induces irs1/2 depletion, insulin resistance, and cell survival deficiencies Curr Biol 14 2004 1650 1656 (Pubitemid 39239362)
    • (2004) Current Biology , vol.14 , Issue.18 , pp. 1650-1656
    • Shah, O.J.1    Wang, Z.2    Hunter, T.3
  • 35
    • 78650243948 scopus 로고    scopus 로고
    • Impact of cellular senescence signature on ageing research
    • E. Sikora, T. Arendt, M. Bennett, and M. Narita Impact of cellular senescence signature on ageing research Ageing Res Rev 10 2011 146 152
    • (2011) Ageing Res Rev , vol.10 , pp. 146-152
    • Sikora, E.1    Arendt, T.2    Bennett, M.3    Narita, M.4
  • 37
    • 34547097247 scopus 로고    scopus 로고
    • Brain IRS2 signaling coordinates life span and nutrient homeostasis
    • DOI 10.1126/science.1142179
    • A. Taguchi, L.M. Wartschow, and M.F. White Brain IRS2 signaling coordinates life span and nutrient homeostasis Science 317 2007 369 372 (Pubitemid 47106376)
    • (2007) Science , vol.317 , Issue.5836 , pp. 369-372
    • Taguchi, A.1    Wartschow, L.M.2    White, M.F.3
  • 38
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • DOI 10.1038/nrm1837, PII NRM1837
    • C.M. Taniguchi, B. Emanuelli, and C.R. Kahn Critical nodes in signalling pathways: insights into insulin action Nat Rev Mol Cell 7 2006 85 96 (Pubitemid 43278292)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 39
    • 79954633863 scopus 로고    scopus 로고
    • Heat shock proteins and Drosophila aging
    • J. Tower Heat shock proteins and Drosophila aging Exp Gerontol 46 2011 355 362
    • (2011) Exp Gerontol , vol.46 , pp. 355-362
    • Tower, J.1
  • 41
    • 14544271073 scopus 로고    scopus 로고
    • Genetics of longevity and aging
    • DOI 10.1146/annurev.med.56.082103.104617
    • J. Vijg, and Y. Suh Genetics of longevity and aging Annu Rev Med 56 2005 193 212 (Pubitemid 40299780)
    • (2005) Annual Review of Medicine , vol.56 , pp. 193-212
    • Vijg, J.1    Suh, Y.2
  • 42
    • 53049108896 scopus 로고    scopus 로고
    • Detoxification reactions: Relevance to aging
    • P. Zimniak Detoxification reactions: relevance to aging Ageing Res Rev 7 2008 281 300
    • (2008) Ageing Res Rev , vol.7 , pp. 281-300
    • Zimniak, P.1


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