Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: Collagen accumulation in the young and loss in the aged

Journal of Molecular and Cellular Cardiology

Volumn 53, Issue 1, 2012, Pages 82-90

  Horn, Margaux A ^a   Graham, Helen K ^a   Richards, Mark A ^a   Clarke, Jessica D ^a   Greensmith, David J ^a   Briston, Sarah J ^a   Hall, Mark C S ^b   Dibb, Katharine M ^a   Trafford, Andrew W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

Author keywords

Aging; Extracellular matrix; Fibrosis; Heart failure; TIMPs

Indexed keywords

BETA ACTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OSTEONECTIN; PROCOLLAGEN C PROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; EXTRACELLULAR MATRIX; FEMALE; HEART FAILURE; HEART MUSCLE; IN VIVO STUDY; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SHEEP; SYSTOLIC BLOOD PRESSURE; TISSUE REGENERATION;

AGE FACTORS; ANIMALS; COLLAGEN; DISEASE MODELS, ANIMAL; ENDOMYOCARDIAL FIBROSIS; EXTRACELLULAR MATRIX; FEMALE; HEART; HEART FAILURE; MYOCARDIAL CONTRACTION; MYOCARDIUM; SHEEP; TISSUE INHIBITOR OF METALLOPROTEINASES; VENTRICULAR REMODELING;

ANIMALIA; OVIS ARIES;

EID: 84861965201     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.03.011     Document Type: Article

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