Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle

Mechanisms of Ageing and Development

Volumn 131, Issue 2, 2010, Pages 79-88

  Ljubicic, Vladimir ^a,b   Menzies, Keir J ^a,b   Hood, David A ^a,b  

^a YORK UNIVERSITY   (Canada)

^b YORK UNIVERSITY   (Canada)

Author keywords

DNA fragmentation; Fission; Fusion; Mitochondrial biogenesis; P66Shc; Protein release

Indexed keywords

APOPTOSIS INDUCING FACTOR; CYTOCHROME C; DYNAMIN RELATED PROTEIN 1; MITOCHONDRIAL PROTEIN; OPTIC ATROPHY TYPE 1 PROTEIN; PROTEIN BAX; PROTEIN P46SHC; SRC HOMOLOGY AND COLLAGEN PROTEIN 66; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL COMPARTMENTALIZATION; CELL ORGANELLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; HEART MITOCHONDRION; HEART MUSCLE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION;

AGING; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CYTOCHROME C GROUP; CYTOCHROMES C; CYTOSOL; MALE; MITOCHONDRIA; MYOCARDIUM; PERMEABILITY; RATS; RATS, INBRED F344; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 77249147323     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.12.004     Document Type: Article

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