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Volumn 18, Issue 3, 2013, Pages 347-357

Antipsychotics activate the TGFβ pathway effector SMAD3

Author keywords

antipsychotics; insulin promoter; SMAD3; TGF

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; INSULIN RECEPTOR; NEUROTRANSMITTER RECEPTOR; PHENOTHIAZINE; PROFENAMINE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84884211426     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.186     Document Type: Article
Times cited : (12)

References (59)
  • 2
    • 21244475081 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: A retrospective cohort study
    • Ostbye T, Curtis LH, Masselink LE, Hutchison S, Wright A, Dans PE et al. Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: a retrospective cohort study. Pharmacoepidemiol Drug Saf 2005; 14: 407-415.
    • (2005) Pharmacoepidemiol Drug Saf , vol.14 , pp. 407-415
    • Ostbye, T.1    Curtis, L.H.2    Masselink, L.E.3    Hutchison, S.4    Wright, A.5    Dans, P.E.6
  • 4
    • 37249034101 scopus 로고    scopus 로고
    • Atypical antipsychotic-induced metabolic side effects: Insights from receptor-binding profiles
    • Nasrallah H. Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry 2008; 13: 27-35.
    • (2008) Mol Psychiatry , vol.13 , pp. 27-35
    • Nasrallah, H.1
  • 5
    • 0014244137 scopus 로고
    • Phenothiazines and diabetes in hospitalized women
    • Tonnard-Neumann E. Phenothiazines and diabetes in hospitalized women. Am J Pychiatry 1968; 124: 978-982.
    • (1968) Am J Pychiatry , vol.124 , pp. 978-982
    • Tonnard-Neumann, E.1
  • 7
    • 9944242312 scopus 로고    scopus 로고
    • Comparative effects of the antipsychotics sulpiride and risperidone in female rats on energy balance, body composition, fat morphology and macronutrient selection
    • Baptista T, de Baptista EA, Lalonde J, Plamondon J, Kin NM, Beaulieu S et al. Comparative effects of the antipsychotics sulpiride and risperidone in female rats on energy balance, body composition, fat morphology and macronutrient selection. Prog Neuropsychopharmacol Biol Psychiatry 2004; 28: 1305-1311.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 1305-1311
    • Baptista, T.1    De Baptista, E.A.2    Lalonde, J.3    Plamondon, J.4    Kin, N.M.5    Beaulieu, S.6
  • 8
    • 63749126381 scopus 로고    scopus 로고
    • How can antipsychotics cause Diabetes Mellitus? Insights based on receptor-binding profiles, humoral factors and transporter proteins
    • Starrenburg FC, Bogers JP. How can antipsychotics cause Diabetes Mellitus? Insights based on receptor-binding profiles, humoral factors and transporter proteins. Eur Psychiatry 2009; 24: 164-170.
    • (2009) Eur Psychiatry , vol.24 , pp. 164-170
    • Starrenburg, F.C.1    Bogers, J.P.2
  • 10
    • 77955830321 scopus 로고    scopus 로고
    • Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen
    • Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B et al. Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen. J Biomol Screen 2010; 15: 663-670.
    • (2010) J Biomol Screen , vol.15 , pp. 663-670
    • Kiselyuk, A.1    Farber-Katz, S.2    Cohen, T.3    Lee, S.H.4    Geron, I.5    Azimi, B.6
  • 11
    • 56649102089 scopus 로고    scopus 로고
    • Genomic convergence analysis of schizophrenia: MRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum
    • Mudge J, Miller NA, Khrebtukova I, Lindquist IE, May GD, Huntley JJ et al. Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum. PLoS One 2008; 3: e3625.
    • (2008) PLoS One , vol.3
    • Mudge, J.1    Miller, N.A.2    Khrebtukova, I.3    Lindquist, I.E.4    May, G.D.5    Huntley, J.J.6
  • 12
    • 53949085543 scopus 로고    scopus 로고
    • Molecular profiles of schizophrenia in the CNS at different stages of illness
    • Narayan S, Tang B, Head SR, Gilmartin TJ, Sutcliffe JG, Dean B et al. Molecular profiles of schizophrenia in the CNS at different stages of illness. Brain Res 2008; 1239: 235-248.
    • (2008) Brain Res , vol.1239 , pp. 235-248
    • Narayan, S.1    Tang, B.2    Head, S.R.3    Gilmartin, T.J.4    Sutcliffe, J.G.5    Dean, B.6
  • 13
    • 0034485840 scopus 로고    scopus 로고
    • Alterations in plasma transforming growth factor beta in normoalbuminuric type 1 and type 2 diabetic patients
    • Azar ST, Salti I, Zantout MS, Major S. Alterations in plasma transforming growth factor beta in normoalbuminuric type 1 and type 2 diabetic patients. J Clin Endocrinol Metab 2000; 85: 4680-4682.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4680-4682
    • Azar, S.T.1    Salti, I.2    Zantout, M.S.3    Major, S.4
  • 14
    • 33244464960 scopus 로고    scopus 로고
    • Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus
    • Smart NG, Apelqvist AA, Gu X, Harmon EB, Topper JN, MacDonald RJ et al. Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus. PLoS Biol 2006; 4: e39.
    • (2006) PLoS Biol , vol.4
    • Smart, N.G.1    Apelqvist, A.A.2    Gu, X.3    Harmon, E.B.4    Topper, J.N.5    MacDonald, R.J.6
  • 15
    • 56049114635 scopus 로고    scopus 로고
    • Insulin gene is a target in activin receptor-like kinase 7 signaling pathway in pancreatic beta-cells
    • Watanabe R, Shen ZP, Tsuda K, Yamada Y. Insulin gene is a target in activin receptor-like kinase 7 signaling pathway in pancreatic beta-cells. Biochem Biophys Res Commun 2008; 377: 867-872.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 867-872
    • Watanabe, R.1    Shen, Z.P.2    Tsuda, K.3    Yamada, Y.4
  • 16
    • 70349656625 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 and incident type 2 diabetes: Results from the MONICA/KORA case-cohort study, 1984-2002
    • Herder C, Zierer A, Koenig W, Roden M, Meisinger C, Thorand B. Transforming growth factor-beta1 and incident type 2 diabetes: results from the MONICA/KORA case-cohort study, 1984-2002. Diabetes Care 2009; 32: 1921-1923.
    • (2009) Diabetes Care , vol.32 , pp. 1921-1923
    • Herder, C.1    Zierer, A.2    Koenig, W.3    Roden, M.4    Meisinger, C.5    Thorand, B.6
  • 17
    • 79551589284 scopus 로고    scopus 로고
    • Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet
    • Tan CK, Leuenberger N, Tan MJ, Yan YW, Chen Y, Kambadur R et al. Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet. Diabetes 2011; 60: 464-476.
    • (2011) Diabetes , vol.60 , pp. 464-476
    • Tan, C.K.1    Leuenberger, N.2    Tan, M.J.3    Yan, Y.W.4    Chen, Y.5    Kambadur, R.6
  • 18
    • 70350495647 scopus 로고    scopus 로고
    • Variations in serum transforming growth factor-beta1 levels with gender, age and lifestyle factors of healthy Japanese adults
    • Lin Y, Nakachi K, Ito Y, Kikuchi S, Tamakoshi A, Yagyu K et al. Variations in serum transforming growth factor-beta1 levels with gender, age and lifestyle factors of healthy Japanese adults. Dis Markers 2009; 27: 23-28.
    • (2009) Dis Markers , vol.27 , pp. 23-28
    • Lin, Y.1    Nakachi, K.2    Ito, Y.3    Kikuchi, S.4    Tamakoshi, A.5    Yagyu, K.6
  • 19
    • 66449119468 scopus 로고    scopus 로고
    • Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function
    • Lin HM, Lee JH, Yadav H, Kamaraju AK, Liu E, Zhigang D et al. Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function. J Biol Chem 2009; 284: 12246-12257.
    • (2009) J Biol Chem , vol.284 , pp. 12246-12257
    • Lin, H.M.1    Lee, J.H.2    Yadav, H.3    Kamaraju, A.K.4    Liu, E.5    Zhigang, D.6
  • 20
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: A comprehensive literature review
    • Newcomer J. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs 2005; 19(Suppl 1): 1-93.
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.1
  • 22
    • 0036161990 scopus 로고    scopus 로고
    • Ziprasidone: An atypical antipsychotic drug for the treatment of schizophrenia
    • Stimmel GL, Gutierrez MA, Lee V. Ziprasidone: an atypical antipsychotic drug for the treatment of schizophrenia. Clin Ther 2002; 24: 21-37.
    • (2002) Clin Ther , vol.24 , pp. 21-37
    • Stimmel, G.L.1    Gutierrez, M.A.2    Lee, V.3
  • 23
    • 77954166205 scopus 로고    scopus 로고
    • From receptor pharmacology to improved outcomes: Individualising the selection, dosing, and switching of antipsychotics
    • Correll C. From receptor pharmacology to improved outcomes: individualising the selection, dosing, and switching of antipsychotics. Eur Psychiatry 2010; 25(Suppl 2): S12-S21.
    • (2010) Eur Psychiatry , vol.25 , Issue.SUPPL. 2
    • Correll, C.1
  • 25
    • 0031854439 scopus 로고    scopus 로고
    • Neurotransmitters and their receptors in the islets of Langerhans of the pancreas: What messages do acetylcholine, glutamate, and GABA transmit?
    • Satin LS, Kinard TA. Neurotransmitters and their receptors in the islets of Langerhans of the pancreas: what messages do acetylcholine, glutamate, and GABA transmit? Endocrine 1998, 8, 213-223.
    • (1998) Endocrine , vol.8 , pp. 213-223
    • Satin, L.S.1    Kinard, T.A.2
  • 26
    • 77954480533 scopus 로고    scopus 로고
    • Serotonin regulates pancreatic beta cell mass during pregnancy
    • Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H et al. Serotonin regulates pancreatic beta cell mass during pregnancy. Nat Med 2010; 16: 804-808.
    • (2010) Nat Med , vol.16 , pp. 804-808
    • Kim, H.1    Toyofuku, Y.2    Lynn, F.C.3    Chak, E.4    Uchida, T.5    Mizukami, H.6
  • 27
    • 70349634805 scopus 로고    scopus 로고
    • Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux
    • Farkas T, Hoyer-Hansen M, Jaattela M. Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux. Autophagy 2009; 5: 1018-1025.
    • (2009) Autophagy , vol.5 , pp. 1018-1025
    • Farkas, T.1    Hoyer-Hansen, M.2    Jaattela, M.3
  • 28
    • 1342265719 scopus 로고    scopus 로고
    • SB-505124 is a selective inhibitor of transforming growth factor-beta type i receptors ALK4, ALK5, and ALK7
    • DaCosta Byfield S, Major C, Laping NJ, Roberts AB. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7. Mol Pharmacol 2004; 65: 744-752.
    • (2004) Mol Pharmacol , vol.65 , pp. 744-752
    • Dacosta Byfield, S.1    Major, C.2    Laping, N.J.3    Roberts, A.B.4
  • 29
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A, Heldin CH. The regulation of TGFbeta signal transduction. Development 2009; 136: 3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 30
    • 58249089671 scopus 로고    scopus 로고
    • Holding their own: The noncanonical roles of Smad proteins
    • Hoover LL, Kubalak SW. Holding their own: the noncanonical roles of Smad proteins. Sci Signal 2008; 1: pe48.
    • (2008) Sci Signal , vol.1
    • Hoover, L.L.1    Kubalak, S.W.2
  • 32
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 1998; 17: 3091-3100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 33
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-beta-Smad signalling
    • ten Dijke P, Hill CS. New insights into TGF-beta-Smad signalling. Trends Biochem Sci 2004; 29: 265-273.
    • (2004) Trends Biochem Sci , vol.29 , pp. 265-273
    • Ten Dijke, P.1    Hill, C.S.2
  • 34
    • 77954312234 scopus 로고    scopus 로고
    • Emerging roles for the TGFbeta family in pancreatic beta-cell homeostasis
    • Brown ML, Schneyer AL. Emerging roles for the TGFbeta family in pancreatic beta-cell homeostasis. Trends Endocrinol Metab 2010; 21: 441-448.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 441-448
    • Brown, M.L.1    Schneyer, A.L.2
  • 35
    • 0033976650 scopus 로고    scopus 로고
    • Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells
    • Sayo Y, Hosokawa H, Imachi H, Murao K, Sato M, Wong NC et al. Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells. Eur J Biochem 2000; 267: 971-978.
    • (2000) Eur J Biochem , vol.267 , pp. 971-978
    • Sayo, Y.1    Hosokawa, H.2    Imachi, H.3    Murao, K.4    Sato, M.5    Wong, N.C.6
  • 36
    • 30444445269 scopus 로고    scopus 로고
    • Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells
    • Kirwan RP, Leonard MO, Murphy M, Clark AF, O'Brien CJ. Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia 2005; 52: 309-324.
    • (2005) Glia , vol.52 , pp. 309-324
    • Kirwan, R.P.1    Leonard, M.O.2    Murphy, M.3    Clark, A.F.4    O'Brien, C.J.5
  • 37
    • 34447522128 scopus 로고    scopus 로고
    • Cell phenotype-specific down-regulation of Smad3 involves decreased gene activation as well as protein degradation
    • Poncelet AC, Schnaper HW, Tan R, Liu Y, Runyan CE. Cell phenotype-specific down-regulation of Smad3 involves decreased gene activation as well as protein degradation. J Biol Chem 2007; 282: 15534-15540.
    • (2007) J Biol Chem , vol.282 , pp. 15534-15540
    • Poncelet, A.C.1    Schnaper, H.W.2    Tan, R.3    Liu, Y.4    Runyan, C.E.5
  • 38
    • 41849145394 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol-3 kinase regulates pancreatic duodenal homeobox-1 in duct cells during pancreatic regeneration
    • Watanabe H, Saito H, Nishimura H, Ueda J, Evers BM. Activation of phosphatidylinositol-3 kinase regulates pancreatic duodenal homeobox-1 in duct cells during pancreatic regeneration. Pancreas 2008; 36: 153-159.
    • (2008) Pancreas , vol.36 , pp. 153-159
    • Watanabe, H.1    Saito, H.2    Nishimura, H.3    Ueda, J.4    Evers, B.M.5
  • 39
    • 14744279743 scopus 로고    scopus 로고
    • Upstream stimulatory factor regulates e box-dependent PAI-1 transcription in human epidermal keratinocytes
    • Allen RR, Qi L, Higgins PJ. Upstream stimulatory factor regulates E box-dependent PAI-1 transcription in human epidermal keratinocytes. J Cell Physiol 2005; 203: 156-165.
    • (2005) J Cell Physiol , vol.203 , pp. 156-165
    • Allen, R.R.1    Qi, L.2    Higgins, P.J.3
  • 40
    • 0035890328 scopus 로고    scopus 로고
    • TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
    • Liu D, Black BL, Derynck R. TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev 2001; 15: 2950-2966.
    • (2001) Genes Dev , vol.15 , pp. 2950-2966
    • Liu, D.1    Black, B.L.2    Derynck, R.3
  • 41
    • 2342514242 scopus 로고    scopus 로고
    • 2004 TGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation
    • Liu D, Kang JS, Derynck R. 2004 TGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation. EMBO J 2004; 23: 1557-1566.
    • (2004) EMBO J , vol.23 , pp. 1557-1566
    • Liu, D.1    Kang, J.S.2    Derynck, R.3
  • 42
    • 20744456269 scopus 로고    scopus 로고
    • NeuroD1 in the endocrine pancreas: Localization and dual function as an activator and repressor
    • Itkin-Ansari P, Marcora E, Geron I, Tyrberg B, Demeterco C, Hao E et al. NeuroD1 in the endocrine pancreas: Localization and dual function as an activator and repressor. Dev Dyn 2005; 233: 946-953.
    • (2005) Dev Dyn , vol.233 , pp. 946-953
    • Itkin-Ansari, P.1    Marcora, E.2    Geron, I.3    Tyrberg, B.4    Demeterco, C.5    Hao, E.6
  • 43
    • 0025292850 scopus 로고
    • MyoD binds cooperatively to two sites in a target enhancer sequence: Occupancy of two sites is required for activation
    • Weintraub H, Davis R, Lockshon D, Lassar A. MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. Proc Natl Acad Sci USA 1990; 87: 5623-5627.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5623-5627
    • Weintraub, H.1    Davis, R.2    Lockshon, D.3    Lassar, A.4
  • 45
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 30 UTRs by comparison of several mammals
    • Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K et al. Systematic discovery of regulatory motifs in human promoters and 30 UTRs by comparison of several mammals. Nature 2005; 434: 338-345.
    • (2005) Nature , vol.434 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5    Lindblad-Toh, K.6
  • 47
    • 2542479890 scopus 로고    scopus 로고
    • Signal transduction and biological functions of bone morphogenetic proteins
    • Chen D, Zhao M, Harris SE, Mi Z. Signal transduction and biological functions of bone morphogenetic proteins. Front Biosci 2004; 9: 349-358.
    • (2004) Front Biosci , vol.9 , pp. 349-358
    • Chen, D.1    Zhao, M.2    Harris, S.E.3    Mi, Z.4
  • 48
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006; 313: 1929-1935.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3    Modell, J.W.4    Blat, I.C.5    Wrobel, M.J.6
  • 49
    • 24044513994 scopus 로고    scopus 로고
    • Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling
    • Sun Y, Lowther W, Kato K, Bianco C, Kenney N, Strizzi L et al. Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling. Oncogene 2005; 24: 5365-5374.
    • (2005) Oncogene , vol.24 , pp. 5365-5374
    • Sun, Y.1    Lowther, W.2    Kato, K.3    Bianco, C.4    Kenney, N.5    Strizzi, L.6
  • 50
    • 77954206949 scopus 로고    scopus 로고
    • A murine model of atypical antipsychoticinduced weight gain and metabolic dysregulation
    • Chapter 9 Unit9 33
    • Coccurello R, Moles A. A murine model of atypical antipsychoticinduced weight gain and metabolic dysregulation. Curr Protoc Neurosci 2010 Chapter 9 Unit9 33.
    • (2010) Curr Protoc Neurosci
    • Coccurello, R.1    Moles, A.2
  • 52
    • 58849138816 scopus 로고    scopus 로고
    • Which comes first: Atypical antipsychotic treatment or cardiometabolic risk?
    • Stahl SM, Mignon L, Meyer JM. Which comes first: atypical antipsychotic treatment or cardiometabolic risk? Acta Psychiatr Scand.2009, 119: 171-179.
    • (2009) Acta Psychiatr Scand , vol.119 , pp. 171-179
    • Stahl, S.M.1    Mignon, L.2    Meyer, J.M.3
  • 53
    • 33244464960 scopus 로고    scopus 로고
    • Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus
    • Smart NG, Apelqvist AA, Gu X, Harmon EB, Topper JN, MacDonald RJ et al. Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus. PLoS Biol 2006; 4: e39.
    • (2006) PLoS Biol , vol.4
    • Smart, N.G.1    Apelqvist, A.A.2    Gu, X.3    Harmon, E.B.4    Topper, J.N.5    MacDonald, R.J.6
  • 54
    • 44949234588 scopus 로고    scopus 로고
    • First-v second-generation antipsychotics and risk for diabetes in schizophrenia: Systematic review and meta-analysis
    • Smith M, Hopkins D, Peveler RC, Holt RI, Woodward M, Ismail K. First-v. second-generation antipsychotics and risk for diabetes in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2008; 192: 406-411.
    • (2008) Br J Psychiatry , vol.192 , pp. 406-411
    • Smith, M.1    Hopkins, D.2    Peveler, R.C.3    Holt, R.I.4    Woodward, M.5    Ismail, K.6
  • 55
    • 70349156383 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and diabetes mellitus in the us food and drug administration adverse event database: A systematic bayesian signal detection analysis
    • Baker RA, Pikalov A, Tran QV, Kremenets T, Arani RB, Doraiswamy PM. Atypical Antipsychotic Drugs and Diabetes Mellitus in the US Food and Drug Administration Adverse Event Database: A Systematic Bayesian Signal Detection Analysis. Psychopharmacol Bull 2009; 42: 11-31.
    • (2009) Psychopharmacol Bull , vol.42 , pp. 11-31
    • Baker, R.A.1    Pikalov, A.2    Tran, Q.V.3    Kremenets, T.4    Arani, R.B.5    Doraiswamy, P.M.6
  • 56
    • 1842633563 scopus 로고    scopus 로고
    • Diabetes mellitus and schizophrenia: Historical perspective
    • Kohen D. Diabetes mellitus and schizophrenia: historical perspective. Br J Psychiatry Suppl 2004; 47: S64-S66.
    • (2004) Br J Psychiatry Suppl , vol.47
    • Kohen, D.1
  • 57
  • 58
    • 77955788858 scopus 로고    scopus 로고
    • Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin
    • Feldkamp MD, O'Donnell SE, Yu L, Shea MA. Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin. Proteins 2010; 78: 2265-2282.
    • (2010) Proteins , vol.78 , pp. 2265-2282
    • Feldkamp, M.D.1    O'Donnell, S.E.2    Yu, L.3    Shea, M.A.4
  • 59
    • 69049085270 scopus 로고    scopus 로고
    • Inhibitors of clathrin-dependent endocytosis enhance TGFbeta signaling and responses
    • Chen CL, Hou WH, Liu IH, Hsiao G, Huang SS, Huang JS. Inhibitors of clathrin-dependent endocytosis enhance TGFbeta signaling and responses. J Cell Sci 2009; 122(Pt 11): 1863-1871.
    • (2009) J Cell Sci , vol.122 , Issue.PART 11 , pp. 1863-1871
    • Chen, C.L.1    Hou, W.H.2    Liu, I.H.3    Hsiao, G.4    Huang, S.S.5    Huang, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.