메뉴 건너뛰기




Volumn 184, Issue 2, 2013, Pages 907-924

Molecular mechanisms of thoracic aortic dissection

Author keywords

Aneurysm; Aortic dissection; Degeneration; Media

Indexed keywords

CHEMOKINE; CYTOKINE; MATRIX METALLOPROTEINASE; OLIGOMER; TISSUE INHIBITOR OF METALLOPROTEINASE;

EID: 84883897534     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.06.007     Document Type: Review
Times cited : (192)

References (192)
  • 1
    • 46049099576 scopus 로고    scopus 로고
    • Acute aortic dissection
    • J. Golledge, and K.A. Eagle Acute aortic dissection Lancet 372 2008 55
    • (2008) Lancet , vol.372 , pp. 55
    • Golledge, J.1    Eagle, K.A.2
  • 2
    • 0942287096 scopus 로고    scopus 로고
    • Acute aortic dissection: Population-based incidence compared with degenerative aortic aneurysm rupture
    • W.D. Clouse, J.W. Hallett Jr., and H.V. Schaff Acute aortic dissection: population-based incidence compared with degenerative aortic aneurysm rupture Mayo Clin Proc 79 2004 176
    • (2004) Mayo Clin Proc , vol.79 , pp. 176
    • Clouse, W.D.1    Hallett, Jr.J.W.2    Schaff, H.V.3
  • 3
    • 0034078516 scopus 로고    scopus 로고
    • Epidemiology and clinicopathology of aortic dissection
    • I. Meszaros, J. Morocz, and J. Szlavi Epidemiology and clinicopathology of aortic dissection Chest 117 2000 1271
    • (2000) Chest , vol.117 , pp. 1271
    • Meszaros, I.1    Morocz, J.2    Szlavi, J.3
  • 5
    • 0005422667 scopus 로고    scopus 로고
    • Histology and ultrastructure
    • H.G. Borst, M.K. Heinemann, C.D. Stone, Churchill Livingstone New York, NY
    • H.G. Borst, M.K. Heinemann, and C.D. Stone Histology and ultrastructure H.G. Borst, M.K. Heinemann, C.D. Stone, Surgical treatment of aortic dissection 1996 Churchill Livingstone New York, NY 37 46
    • (1996) Surgical Treatment of Aortic Dissection , pp. 37-46
    • Borst, H.G.1    Heinemann, M.K.2    Stone, C.D.3
  • 6
    • 0032708095 scopus 로고    scopus 로고
    • Natural history, pathogenesis, and etiology of thoracic aortic aneurysms and dissections
    • M.A. Coady, J.A. Rizzo, and L.J. Goldstein Natural history, pathogenesis, and etiology of thoracic aortic aneurysms and dissections Cardiol Clin 17 1999 615
    • (1999) Cardiol Clin , vol.17 , pp. 615
    • Coady, M.A.1    Rizzo, J.A.2    Goldstein, L.J.3
  • 7
    • 33748077412 scopus 로고    scopus 로고
    • Surgical pathology of the ascending aorta: A clinicopathologic study of 513 cases
    • J.L. Homme, M.C. Aubry, and W.D. Edwards Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases Am J Surg Pathol 30 2006 1159
    • (2006) Am J Surg Pathol , vol.30 , pp. 1159
    • Homme, J.L.1    Aubry, M.C.2    Edwards, W.D.3
  • 8
    • 33644583300 scopus 로고    scopus 로고
    • Characterization of the inflammatory and apoptotic cells in the aortas of patients with ascending thoracic aortic aneurysms and dissections
    • R. He, D.C. Guo, and A.L. Estrera Characterization of the inflammatory and apoptotic cells in the aortas of patients with ascending thoracic aortic aneurysms and dissections J Thorac Cardiovasc Surg 131 2006 671
    • (2006) J Thorac Cardiovasc Surg , vol.131 , pp. 671
    • He, R.1    Guo, D.C.2    Estrera, A.L.3
  • 10
    • 0025367556 scopus 로고
    • Alterations of elastic architecture in human aortic dissecting aneurysm
    • Y. Nakashima, Y. Shiokawa, and K. Sueishi Alterations of elastic architecture in human aortic dissecting aneurysm Lab Invest 62 1990 751
    • (1990) Lab Invest , vol.62 , pp. 751
    • Nakashima, Y.1    Shiokawa, Y.2    Sueishi, K.3
  • 11
    • 24344456452 scopus 로고    scopus 로고
    • Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection
    • X. Wang, S.A. LeMaire, and L. Chen Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection Surgery 138 2005 352
    • (2005) Surgery , vol.138 , pp. 352
    • Wang, X.1    Lemaire, S.A.2    Chen, L.3
  • 12
    • 0033110425 scopus 로고    scopus 로고
    • Alteration of cross-linking amino acids of elastin in human aorta in association with dissecting aneurysm: Analysis using high performance liquid chromatography
    • M. Watanabe, and T. Sawai Alteration of cross-linking amino acids of elastin in human aorta in association with dissecting aneurysm: analysis using high performance liquid chromatography Tohoku J Exp Med 187 1999 291
    • (1999) Tohoku J Exp Med , vol.187 , pp. 291
    • Watanabe, M.1    Sawai, T.2
  • 13
    • 0037262361 scopus 로고    scopus 로고
    • A critical role for elastin signaling in vascular morphogenesis and disease
    • S.K. Karnik, B.S. Brooke, and A. Bayes-Genis A critical role for elastin signaling in vascular morphogenesis and disease Development 130 2003 411
    • (2003) Development , vol.130 , pp. 411
    • Karnik, S.K.1    Brooke, B.S.2    Bayes-Genis, A.3
  • 14
    • 2342617472 scopus 로고    scopus 로고
    • 3 binds a unique non-RGD site near the C-terminus of human tropoelastin
    • 3 binds a unique non-RGD site near the C-terminus of human tropoelastin Biochimie 86 2004 173
    • (2004) Biochimie , vol.86 , pp. 173
    • Rodgers, U.R.1    Weiss, A.S.2
  • 15
    • 0037160109 scopus 로고    scopus 로고
    • Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells
    • S. Mochizuki, B. Brassart, and A. Hinek Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells J Biol Chem 277 2002 44854
    • (2002) J Biol Chem , vol.277 , pp. 44854
    • Mochizuki, S.1    Brassart, B.2    Hinek, A.3
  • 16
    • 23944449567 scopus 로고    scopus 로고
    • Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries
    • J.E. Wagenseil, N.L. Nerurkar, and R.H. Knutsen Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries Am J Physiol Heart Circ Physiol 289 2005 H1209
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. 1209
    • Wagenseil, J.E.1    Nerurkar, N.L.2    Knutsen, R.H.3
  • 17
    • 0032533870 scopus 로고    scopus 로고
    • Novel arterial pathology in mice and humans hemizygous for elastin
    • D.Y. Li, G. Faury, and D.G. Taylor Novel arterial pathology in mice and humans hemizygous for elastin J Clin Invest 102 1998 1783
    • (1998) J Clin Invest , vol.102 , pp. 1783
    • Li, D.Y.1    Faury, G.2    Taylor, D.G.3
  • 19
    • 0037462678 scopus 로고    scopus 로고
    • Latent transforming growth factor β-binding protein 1 interacts with fibrillin and is a microfibril-associated protein
    • Z. Isogai, R.N. Ono, and S. Ushiro Latent transforming growth factor β-binding protein 1 interacts with fibrillin and is a microfibril- associated protein J Biol Chem 278 2003 2750
    • (2003) J Biol Chem , vol.278 , pp. 2750
    • Isogai, Z.1    Ono, R.N.2    Ushiro, S.3
  • 21
    • 0037373277 scopus 로고    scopus 로고
    • Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome
    • E.R. Neptune, P.A. Frischmeyer, and D.E. Arking Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome Nat Genet 33 2003 407
    • (2003) Nat Genet , vol.33 , pp. 407
    • Neptune, E.R.1    Frischmeyer, P.A.2    Arking, D.E.3
  • 23
    • 0142231565 scopus 로고    scopus 로고
    • Fibrillin-1 and -2 contain heparin-binding sites important for matrix deposition and that support cell attachment
    • T.M. Ritty, T.J. Broekelmann, and C.C. Werneck Fibrillin-1 and -2 contain heparin-binding sites important for matrix deposition and that support cell attachment Biochem J 375 2003 425
    • (2003) Biochem J , vol.375 , pp. 425
    • Ritty, T.M.1    Broekelmann, T.J.2    Werneck, C.C.3
  • 24
  • 25
    • 33646340434 scopus 로고    scopus 로고
    • Fibrillins 1 and 2 perform partially overlapping functions during aortic development
    • L. Carta, L. Pereira, and E. Arteaga-Solis Fibrillins 1 and 2 perform partially overlapping functions during aortic development J Biol Chem 281 2006 8016
    • (2006) J Biol Chem , vol.281 , pp. 8016
    • Carta, L.1    Pereira, L.2    Arteaga-Solis, E.3
  • 26
    • 77956911290 scopus 로고    scopus 로고
    • Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF β
    • T. Massam-Wu, M. Chiu, and R. Choudhury Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF β J Cell Sci 123 2010 3006
    • (2010) J Cell Sci , vol.123 , pp. 3006
    • Massam-Wu, T.1    Chiu, M.2    Choudhury, R.3
  • 27
    • 67650875881 scopus 로고    scopus 로고
    • Vascular extracellular matrix and arterial mechanics
    • J.E. Wagenseil, and R.P. Mecham Vascular extracellular matrix and arterial mechanics Physiol Rev 89 2009 957
    • (2009) Physiol Rev , vol.89 , pp. 957
    • Wagenseil, J.E.1    Mecham, R.P.2
  • 28
    • 54449085747 scopus 로고    scopus 로고
    • Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems
    • J.S. Weinbaum, T.J. Broekelmann, and R.A. Pierce Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems J Biol Chem 283 2008 25533
    • (2008) J Biol Chem , vol.283 , pp. 25533
    • Weinbaum, J.S.1    Broekelmann, T.J.2    Pierce, R.A.3
  • 29
    • 33646809625 scopus 로고    scopus 로고
    • Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function
    • E. Chen, J.D. Larson, and S.C. Ekker Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function Blood 107 2006 4364
    • (2006) Blood , vol.107 , pp. 4364
    • Chen, E.1    Larson, J.D.2    Ekker, S.C.3
  • 30
    • 0028961103 scopus 로고
    • The association of human fibulin-1 with elastic fibers: An immunohistological, ultrastructural, and RNA study
    • E.F. Roark, D.R. Keene, and C.C. Haudenschild The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study J Histochem Cytochem 43 1995 401
    • (1995) J Histochem Cytochem , vol.43 , pp. 401
    • Roark, E.F.1    Keene, D.R.2    Haudenschild, C.C.3
  • 31
    • 0034802720 scopus 로고    scopus 로고
    • Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice
    • G. Kostka, R. Giltay, and W. Bloch Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice Mol Cell Biol 21 2001 7025
    • (2001) Mol Cell Biol , vol.21 , pp. 7025
    • Kostka, G.1    Giltay, R.2    Bloch, W.3
  • 32
    • 36248956676 scopus 로고    scopus 로고
    • Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice
    • P.J. McLaughlin, B. Bakall, and J. Choi Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice Hum Mol Genet 16 2007 3059
    • (2007) Hum Mol Genet , vol.16 , pp. 3059
    • McLaughlin, P.J.1    Bakall, B.2    Choi, J.3
  • 33
    • 38549085294 scopus 로고    scopus 로고
    • Fibulin-2 is dispensable for mouse development and elastic fiber formation
    • F.X. Sicot, T. Tsuda, and D. Markova Fibulin-2 is dispensable for mouse development and elastic fiber formation Mol Cell Biol 28 2008 1061
    • (2008) Mol Cell Biol , vol.28 , pp. 1061
    • Sicot, F.X.1    Tsuda, T.2    Markova, D.3
  • 34
    • 73149111728 scopus 로고    scopus 로고
    • Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase
    • M. Horiguchi, T. Inoue, and T. Ohbayashi Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase Proc Natl Acad Sci U S A 106 2009 19029
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19029
    • Horiguchi, M.1    Inoue, T.2    Ohbayashi, T.3
  • 35
    • 57749098804 scopus 로고    scopus 로고
    • Lysyl oxidase binds transforming growth factor-β and regulates its signaling via amine oxidase activity
    • P. Atsawasuwan, Y. Mochida, and M. Katafuchi Lysyl oxidase binds transforming growth factor-β and regulates its signaling via amine oxidase activity J Biol Chem 283 2008 34229
    • (2008) J Biol Chem , vol.283 , pp. 34229
    • Atsawasuwan, P.1    Mochida, Y.2    Katafuchi, M.3
  • 36
    • 0037027504 scopus 로고    scopus 로고
    • Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice
    • J.M. Maki, J. Rasanen, and H. Tikkanen Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice Circulation 106 2002 2503
    • (2002) Circulation , vol.106 , pp. 2503
    • Maki, J.M.1    Rasanen, J.2    Tikkanen, H.3
  • 37
    • 0037049996 scopus 로고    scopus 로고
    • Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo
    • H. Yanagisawa, E.C. Davis, and B.C. Starcher Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo Nature 415 2002 168
    • (2002) Nature , vol.415 , pp. 168
    • Yanagisawa, H.1    Davis, E.C.2    Starcher, B.C.3
  • 38
    • 20044379927 scopus 로고    scopus 로고
    • Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration
    • J.A. Spencer, S.L. Hacker, and E.C. Davis Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration Proc Natl Acad Sci U S A 102 2005 2946
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2946
    • Spencer, J.A.1    Hacker, S.L.2    Davis, E.C.3
  • 40
    • 0027461783 scopus 로고
    • Emilin, a component of elastic fibers preferentially located at the elastin-microfibrils interface
    • G.M. Bressan, D. Daga-Gordini, and A. Colombatti Emilin, a component of elastic fibers preferentially located at the elastin-microfibrils interface J Cell Biol 121 1993 201
    • (1993) J Cell Biol , vol.121 , pp. 201
    • Bressan, G.M.1    Daga-Gordini, D.2    Colombatti, A.3
  • 41
    • 0347356370 scopus 로고    scopus 로고
    • EMILIN-1 deficiency induces elastogenesis and vascular cell defects
    • M. Zanetti, P. Braghetta, and P. Sabatelli EMILIN-1 deficiency induces elastogenesis and vascular cell defects Mol Cell Biol 24 2004 638
    • (2004) Mol Cell Biol , vol.24 , pp. 638
    • Zanetti, M.1    Braghetta, P.2    Sabatelli, P.3
  • 42
    • 33644751775 scopus 로고    scopus 로고
    • Emilin1 links TGF-β maturation to blood pressure homeostasis
    • L. Zacchigna, C. Vecchione, and A. Notte Emilin1 links TGF-β maturation to blood pressure homeostasis Cell 124 2006 929
    • (2006) Cell , vol.124 , pp. 929
    • Zacchigna, L.1    Vecchione, C.2    Notte, A.3
  • 43
    • 0035853726 scopus 로고    scopus 로고
    • Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily
    • R. Doliana, S. Bot, and G. Mungiguerra Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily J Biol Chem 276 2001 12003
    • (2001) J Biol Chem , vol.276 , pp. 12003
    • Doliana, R.1    Bot, S.2    Mungiguerra, G.3
  • 44
    • 84859503411 scopus 로고    scopus 로고
    • EMILIN-3, peculiar member of elastin microfibril interface-located protein (EMILIN) family, has distinct expression pattern, forms oligomeric assemblies, and serves as transforming growth factor β (TGF-β) antagonist
    • A. Schiavinato, A.K. Becker, and M. Zanetti EMILIN-3, peculiar member of elastin microfibril interface-located protein (EMILIN) family, has distinct expression pattern, forms oligomeric assemblies, and serves as transforming growth factor β (TGF-β) antagonist J Biol Chem 287 2012 11498
    • (2012) J Biol Chem , vol.287 , pp. 11498
    • Schiavinato, A.1    Becker, A.K.2    Zanetti, M.3
  • 45
    • 0032572410 scopus 로고    scopus 로고
    • 1 mediates a unique collagen-dependent proliferation pathway in vivo
    • 1 mediates a unique collagen-dependent proliferation pathway in vivo J Cell Biol 142 1998 587
    • (1998) J Cell Biol , vol.142 , pp. 587
    • Pozzi, A.1    Wary, K.K.2    Giancotti, F.G.3
  • 46
    • 0023032847 scopus 로고
    • Histological pattern and changes in extracellular matrix in aortic dissections
    • H. Sariola, T. Viljanen, and R. Luosto Histological pattern and changes in extracellular matrix in aortic dissections J Clin Pathol 39 1986 1074
    • (1986) J Clin Pathol , vol.39 , pp. 1074
    • Sariola, H.1    Viljanen, T.2    Luosto, R.3
  • 47
    • 0033948539 scopus 로고    scopus 로고
    • Collagen and elastin degradation by matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in aortic dissection
    • T. Ishii, and N. Asuwa Collagen and elastin degradation by matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in aortic dissection Hum Pathol 31 2000 640
    • (2000) Hum Pathol , vol.31 , pp. 640
    • Ishii, T.1    Asuwa, N.2
  • 48
    • 33747203246 scopus 로고    scopus 로고
    • Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection
    • X. Wang, S.A. LeMaire, and L. Chen Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection Circulation 114 2006 I200
    • (2006) Circulation , vol.114 , pp. 200
    • Wang, X.1    Lemaire, S.A.2    Chen, L.3
  • 49
    • 38749142531 scopus 로고    scopus 로고
    • Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta
    • L. de Figueiredo Borges, R.G. Jaldin, and R.R. Dias Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta Hum Pathol 39 2008 437
    • (2008) Hum Pathol , vol.39 , pp. 437
    • De Figueiredo Borges, L.1    Jaldin, R.G.2    Dias, R.R.3
  • 50
    • 33747420371 scopus 로고    scopus 로고
    • Gene expression in acute Stanford type A dissection: A comparative microarray study
    • B.T. Weis-Muller, O. Modlich, and I. Drobinskaya Gene expression in acute Stanford type A dissection: a comparative microarray study J Transl Med 4 2006 29
    • (2006) J Transl Med , vol.4 , pp. 29
    • Weis-Muller, B.T.1    Modlich, O.2    Drobinskaya, I.3
  • 51
    • 0346059549 scopus 로고    scopus 로고
    • Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture
    • O. Rahkonen, M. Su, and H. Hakovirta Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture Circ Res 94 2004 83
    • (2004) Circ Res , vol.94 , pp. 83
    • Rahkonen, O.1    Su, M.2    Hakovirta, H.3
  • 52
    • 0031867067 scopus 로고    scopus 로고
    • A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene
    • S.G. Hormuzdi, R. Penttinen, and R. Jaenisch A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene Mol Cell Biol 18 1998 3368
    • (1998) Mol Cell Biol , vol.18 , pp. 3368
    • Hormuzdi, S.G.1    Penttinen, R.2    Jaenisch, R.3
  • 53
    • 79952836042 scopus 로고    scopus 로고
    • Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: A novel model of the vascular type of Ehlers-Danlos syndrome
    • L.B. Smith, P.W. Hadoke, and E. Dyer Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers-Danlos syndrome Cardiovasc Res 90 2011 182
    • (2011) Cardiovasc Res , vol.90 , pp. 182
    • Smith, L.B.1    Hadoke, P.W.2    Dyer, E.3
  • 54
    • 33750437433 scopus 로고    scopus 로고
    • Lysyl oxidase: An oxidative enzyme and effector of cell function
    • H.A. Lucero, and H.M. Kagan Lysyl oxidase: an oxidative enzyme and effector of cell function Cell Mol Life Sci 63 2006 2304
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2304
    • Lucero, H.A.1    Kagan, H.M.2
  • 55
    • 0842310831 scopus 로고    scopus 로고
    • Elastic fiber homeostasis requires lysyl oxidase-like 1 protein
    • X. Liu, Y. Zhao, and J. Gao Elastic fiber homeostasis requires lysyl oxidase-like 1 protein Nat Genet 36 2004 178
    • (2004) Nat Genet , vol.36 , pp. 178
    • Liu, X.1    Zhao, Y.2    Gao, J.3
  • 56
    • 37549007267 scopus 로고    scopus 로고
    • Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation
    • P.A. Hurtado, S. Vora, and S.S. Sume Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation Biochem Biophys Res Commun 366 2008 156
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 156
    • Hurtado, P.A.1    Vora, S.2    Sume, S.S.3
  • 57
    • 34447565889 scopus 로고    scopus 로고
    • Regulation of elastin promoter by lysyl oxidase and growth factors: Cross control of lysyl oxidase on TGF-β1 effects
    • R. Oleggini, N. Gastaldo, and A. Di Donato Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-β1 effects Matrix Biol 26 2007 494
    • (2007) Matrix Biol , vol.26 , pp. 494
    • Oleggini, R.1    Gastaldo, N.2    Di Donato, A.3
  • 58
    • 0034680779 scopus 로고    scopus 로고
    • Lysyl oxidase activates the transcription activity of human collagene III promoter: Possible involvement of Ku antigen
    • M. Giampuzzi, G. Botti, and M. Di Duca Lysyl oxidase activates the transcription activity of human collagene III promoter: possible involvement of Ku antigen J Biol Chem 275 2000 36341
    • (2000) J Biol Chem , vol.275 , pp. 36341
    • Giampuzzi, M.1    Botti, G.2    Di Duca, M.3
  • 59
    • 1842280744 scopus 로고
    • Histology of the aortic media in dissecting aneurysms
    • G. Manley Histology of the aortic media in dissecting aneurysms J Clin Pathol 17 1964 220
    • (1964) J Clin Pathol , vol.17 , pp. 220
    • Manley, G.1
  • 60
    • 0032917384 scopus 로고    scopus 로고
    • Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells
    • S.P. Evanko, J.C. Angello, and T.N. Wight Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells Arterioscler Thromb Vasc Biol 19 1999 1004
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1004
    • Evanko, S.P.1    Angello, J.C.2    Wight, T.N.3
  • 61
    • 42649136260 scopus 로고    scopus 로고
    • Arterial remodeling in vascular disease: A key role for hyaluronan and versican
    • T.N. Wight Arterial remodeling in vascular disease: a key role for hyaluronan and versican Front Biosci 13 2008 4933
    • (2008) Front Biosci , vol.13 , pp. 4933
    • Wight, T.N.1
  • 62
    • 0035126306 scopus 로고    scopus 로고
    • Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0)
    • A.D. Theocharis, I. Tsolakis, and A. Hjerpe Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0) Atherosclerosis 154 2001 367
    • (2001) Atherosclerosis , vol.154 , pp. 367
    • Theocharis, A.D.1    Tsolakis, I.2    Hjerpe, A.3
  • 63
    • 0031766714 scopus 로고    scopus 로고
    • Distribution of hyaluronan and dermatan/chondroitin sulfate proteoglycans in human aortic dissection
    • P.S. Gutierrez, M.M. Reis, and M.L. Higuchi Distribution of hyaluronan and dermatan/chondroitin sulfate proteoglycans in human aortic dissection Connect Tissue Res 37 1998 151
    • (1998) Connect Tissue Res , vol.37 , pp. 151
    • Gutierrez, P.S.1    Reis, M.M.2    Higuchi, M.L.3
  • 64
    • 0031902035 scopus 로고    scopus 로고
    • Leucine-rich repeat glycoproteins of the extracellular matrix
    • A.M. Hocking, T. Shinomura, and D.J. McQuillan Leucine-rich repeat glycoproteins of the extracellular matrix Matrix Biol 17 1998 1
    • (1998) Matrix Biol , vol.17 , pp. 1
    • Hocking, A.M.1    Shinomura, T.2    McQuillan, D.J.3
  • 65
    • 34249734812 scopus 로고    scopus 로고
    • Biglycan deficiency causes spontaneous aortic dissection and rupture in mice
    • A.M. Heegaard, A. Corsi, and C.C. Danielsen Biglycan deficiency causes spontaneous aortic dissection and rupture in mice Circulation 115 2007 2731
    • (2007) Circulation , vol.115 , pp. 2731
    • Heegaard, A.M.1    Corsi, A.2    Danielsen, C.C.3
  • 66
    • 65549100752 scopus 로고    scopus 로고
    • Pathway analysis of differentially expressed genes in patients with acute aortic dissection
    • S.A. Mohamed, H.H. Sievers, and T. Hanke Pathway analysis of differentially expressed genes in patients with acute aortic dissection Biomark Insights 4 2009 81
    • (2009) Biomark Insights , vol.4 , pp. 81
    • Mohamed, S.A.1    Sievers, H.H.2    Hanke, T.3
  • 67
    • 70450253102 scopus 로고    scopus 로고
    • A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: Functions and mechanisms
    • S.S. Apte A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms J Biol Chem 284 2009 31493
    • (2009) J Biol Chem , vol.284 , pp. 31493
    • Apte, S.S.1
  • 68
    • 23044479358 scopus 로고    scopus 로고
    • Altered patterns of gene expression specific to thoracic aortic aneurysms: Microarray analysis of surgically resected specimens
    • T. Taketani, Y. Imai, and T. Morota Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens Int Heart J 46 2005 265
    • (2005) Int Heart J , vol.46 , pp. 265
    • Taketani, T.1    Imai, Y.2    Morota, T.3
  • 69
    • 84872788994 scopus 로고    scopus 로고
    • ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections
    • P. Ren, L. Zhang, and G. Xu ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections Ann Thorac Surg 95 2013 570
    • (2013) Ann Thorac Surg , vol.95 , pp. 570
    • Ren, P.1    Zhang, L.2    Xu, G.3
  • 70
    • 18744416052 scopus 로고    scopus 로고
    • Gene expression profiles in the acutely dissected human aorta
    • B.T. Muller, O. Modlich, and H.B. Prisack Gene expression profiles in the acutely dissected human aorta Eur J Vasc Endovasc Surg 24 2002 356
    • (2002) Eur J Vasc Endovasc Surg , vol.24 , pp. 356
    • Muller, B.T.1    Modlich, O.2    Prisack, H.B.3
  • 71
    • 35148840431 scopus 로고    scopus 로고
    • Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model
    • S. Hassane, N. Claij, and I.S. Lantinga-van Leeuwen Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model Arterioscler Thromb Vasc Biol 27 2007 2177
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2177
    • Hassane, S.1    Claij, N.2    Lantinga-Van Leeuwen, I.S.3
  • 72
    • 0033547729 scopus 로고    scopus 로고
    • Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms
    • E.L. Henderson, Y.J. Geng, and G.K. Sukhova Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms Circulation 99 1999 96
    • (1999) Circulation , vol.99 , pp. 96
    • Henderson, E.L.1    Geng, Y.J.2    Sukhova, G.K.3
  • 73
    • 0031044735 scopus 로고    scopus 로고
    • Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms
    • A. Lopez-Candales, D.R. Holmes, and S. Liao Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms Am J Pathol 150 1997 993
    • (1997) Am J Pathol , vol.150 , pp. 993
    • Lopez-Candales, A.1    Holmes, D.R.2    Liao, S.3
  • 74
    • 0032841509 scopus 로고    scopus 로고
    • Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation
    • C. Ihling, T. Szombathy, and K. Nampoothiri Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation Heart 82 1999 286
    • (1999) Heart , vol.82 , pp. 286
    • Ihling, C.1    Szombathy, T.2    Nampoothiri, K.3
  • 75
    • 0035908959 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome
    • H. Nagashima, Y. Sakomura, and Y. Aoka Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome Circulation 104 2001 I282
    • (2001) Circulation , vol.104 , pp. 282
    • Nagashima, H.1    Sakomura, Y.2    Aoka, Y.3
  • 76
    • 48249133229 scopus 로고    scopus 로고
    • Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration
    • M.C. Clarke, T.D. Littlewood, and N. Figg Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration Circ Res 102 2008 1529
    • (2008) Circ Res , vol.102 , pp. 1529
    • Clarke, M.C.1    Littlewood, T.D.2    Figg, N.3
  • 77
    • 0034808341 scopus 로고    scopus 로고
    • Smooth muscle cells of the media in the dilatative pathology of ascending thoracic aorta: Morphology, immunoreactivity for osteopontin, matrix metalloproteinases, and their inhibitors
    • V. Lesauskaite, P. Tanganelli, and C. Sassi Smooth muscle cells of the media in the dilatative pathology of ascending thoracic aorta: morphology, immunoreactivity for osteopontin, matrix metalloproteinases, and their inhibitors Hum Pathol 32 2001 1003
    • (2001) Hum Pathol , vol.32 , pp. 1003
    • Lesauskaite, V.1    Tanganelli, P.2    Sassi, C.3
  • 78
    • 74749088725 scopus 로고    scopus 로고
    • Disruption of actin cytoskeleton mediates loss of tensile stress induced early phenotypic modulation of vascular smooth muscle cells in organ culture
    • J.P. Zheng, D. Ju, and J. Shen Disruption of actin cytoskeleton mediates loss of tensile stress induced early phenotypic modulation of vascular smooth muscle cells in organ culture Exp Mol Pathol 88 2010 52
    • (2010) Exp Mol Pathol , vol.88 , pp. 52
    • Zheng, J.P.1    Ju, D.2    Shen, J.3
  • 79
    • 46049100375 scopus 로고    scopus 로고
    • A proteomic study of the aortic media in human thoracic aortic dissection: Implication for oxidative stress
    • M. Liao, Z. Liu, and J. Bao A proteomic study of the aortic media in human thoracic aortic dissection: implication for oxidative stress J Thorac Cardiovasc Surg 136 2008 65
    • (2008) J Thorac Cardiovasc Surg , vol.136 , pp. 65
    • Liao, M.1    Liu, Z.2    Bao, J.3
  • 80
    • 78249273251 scopus 로고    scopus 로고
    • Inflammation and immune response in acute aortic dissection
    • F. del Porto, M. Proietta, and L. Tritapepe Inflammation and immune response in acute aortic dissection Ann Med 42 2010 622
    • (2010) Ann Med , vol.42 , pp. 622
    • Del Porto, F.1    Proietta, M.2    Tritapepe, L.3
  • 82
    • 76449117303 scopus 로고    scopus 로고
    • The amounts of alpha 1 antitrypsin protein are reduced in the vascular wall of the acutely dissected human ascending aorta
    • T. Schachner, G. Golderer, and B. Sarg The amounts of alpha 1 antitrypsin protein are reduced in the vascular wall of the acutely dissected human ascending aorta Eur J Cardiothorac Surg 37 2010 684
    • (2010) Eur J Cardiothorac Surg , vol.37 , pp. 684
    • Schachner, T.1    Golderer, G.2    Sarg, B.3
  • 83
    • 0036968857 scopus 로고    scopus 로고
    • H2 predominant immune responses prevail in human abdominal aortic aneurysm
    • H2 predominant immune responses prevail in human abdominal aortic aneurysm Am J Pathol 161 2002 499
    • (2002) Am J Pathol , vol.161 , pp. 499
    • Schönbeck, U.1    Sukhova, G.K.2    Gerdes, N.3
  • 84
    • 0842300338 scopus 로고    scopus 로고
    • Key roles of CD4+ T cells and IFN-γ in the development of abdominal aortic aneurysms in a murine model
    • W. Xiong, Y. Zhao, and A. Prall Key roles of CD4+ T cells and IFN-γ in the development of abdominal aortic aneurysms in a murine model J Immunol 172 2004 2607
    • (2004) J Immunol , vol.172 , pp. 2607
    • Xiong, W.1    Zhao, Y.2    Prall, A.3
  • 85
    • 43049104500 scopus 로고    scopus 로고
    • Fragments of extracellular matrix as mediators of inflammation
    • T.L. Adair-Kirk, and R.M. Senior Fragments of extracellular matrix as mediators of inflammation Int J Biochem Cell Biol 40 2008 1101
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1101
    • Adair-Kirk, T.L.1    Senior, R.M.2
  • 86
    • 77957221743 scopus 로고    scopus 로고
    • The impact of the extracellular matrix on inflammation
    • L. Sorokin The impact of the extracellular matrix on inflammation Nat Rev Immunol 10 2010 712
    • (2010) Nat Rev Immunol , vol.10 , pp. 712
    • Sorokin, L.1
  • 87
    • 33644828187 scopus 로고    scopus 로고
    • A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
    • N.M. Weathington, A.H. van Houwelingen, and B.D. Noerager A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation Nat Med 12 2006 317
    • (2006) Nat Med , vol.12 , pp. 317
    • Weathington, N.M.1    Van Houwelingen, A.H.2    Noerager, B.D.3
  • 88
    • 45949089501 scopus 로고    scopus 로고
    • A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
    • A. Gaggar, P.L. Jackson, and B.D. Noerager A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation J Immunol 180 2008 5662
    • (2008) J Immunol , vol.180 , pp. 5662
    • Gaggar, A.1    Jackson, P.L.2    Noerager, B.D.3
  • 89
    • 21544434615 scopus 로고    scopus 로고
    • Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes
    • R. Debret, F. Antonicelli, and A. Theill Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes Arterioscler Thromb Vasc Biol 25 2005 1353
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1353
    • Debret, R.1    Antonicelli, F.2    Theill, A.3
  • 90
    • 69949175486 scopus 로고    scopus 로고
    • Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
    • A. Babelova, K. Moreth, and W. Tsalastra-Greul Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors J Biol Chem 284 2009 24035
    • (2009) J Biol Chem , vol.284 , pp. 24035
    • Babelova, A.1    Moreth, K.2    Tsalastra-Greul, W.3
  • 91
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by Toll-like receptors and hyaluronan
    • D. Jiang, J. Liang, and J. Fan Regulation of lung injury and repair by Toll-like receptors and hyaluronan Nat Med 11 2005 1173
    • (2005) Nat Med , vol.11 , pp. 1173
    • Jiang, D.1    Liang, J.2    Fan, J.3
  • 92
    • 0036696905 scopus 로고    scopus 로고
    • Regulation of monocyte gene expression by the extracellular matrix and its functional implications
    • A.R. de Fougerolles, and V.E. Koteliansky Regulation of monocyte gene expression by the extracellular matrix and its functional implications Immunol Rev 186 2002 208
    • (2002) Immunol Rev , vol.186 , pp. 208
    • De Fougerolles, A.R.1    Koteliansky, V.E.2
  • 93
    • 27744546211 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase gene disruption and vitamin e administration diminish atherosclerosis and oxidative stress in apolipoprotein e deficient mice through a final common pathway
    • L. Zhao, D. Pratico, and D.J. Rader 12/15-Lipoxygenase gene disruption and vitamin E administration diminish atherosclerosis and oxidative stress in apolipoprotein E deficient mice through a final common pathway Prostaglandins Other Lipid Mediat 78 2005 185
    • (2005) Prostaglandins Other Lipid Mediat , vol.78 , pp. 185
    • Zhao, L.1    Pratico, D.2    Rader, D.J.3
  • 94
    • 84871304112 scopus 로고    scopus 로고
    • Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection
    • T. Kurihara, R. Shimizu-Hirota, and M. Shimoda Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection Circulation 126 2012 3070
    • (2012) Circulation , vol.126 , pp. 3070
    • Kurihara, T.1    Shimizu-Hirota, R.2    Shimoda, M.3
  • 95
    • 28344447007 scopus 로고    scopus 로고
    • Predominance of type 1 CD4+ T cells in human abdominal aortic aneurysm
    • C. Galle, L. Schandene, and P. Stordeur Predominance of type 1 CD4+ T cells in human abdominal aortic aneurysm Clin Exp Immunol 142 2005 519
    • (2005) Clin Exp Immunol , vol.142 , pp. 519
    • Galle, C.1    Schandene, L.2    Stordeur, P.3
  • 96
    • 70349115558 scopus 로고    scopus 로고
    • Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm
    • K.D. Rizas, N. Ippagunta, and M.D. Tilson III Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm Cardiol Rev 17 2009 201
    • (2009) Cardiol Rev , vol.17 , pp. 201
    • Rizas, K.D.1    Ippagunta, N.2    Tilson III, M.D.3
  • 97
    • 33646449061 scopus 로고    scopus 로고
    • Inflammation and cellular immune responses in abdominal aortic aneurysms
    • K. Shimizu, R.N. Mitchell, and P. Libby Inflammation and cellular immune responses in abdominal aortic aneurysms Arterioscler Thromb Vasc Biol 26 2006 987
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 987
    • Shimizu, K.1    Mitchell, R.N.2    Libby, P.3
  • 98
    • 0034177805 scopus 로고    scopus 로고
    • Effect of impaired vasa vasorum flow on the structure and mechanics of the thoracic aorta: Implications for the pathogenesis of aortic dissection
    • D. Angouras, D.P. Sokolis, and T. Dosios Effect of impaired vasa vasorum flow on the structure and mechanics of the thoracic aorta: implications for the pathogenesis of aortic dissection Eur J Cardiothorac Surg 17 2000 468
    • (2000) Eur J Cardiothorac Surg , vol.17 , pp. 468
    • Angouras, D.1    Sokolis, D.P.2    Dosios, T.3
  • 99
    • 77957748627 scopus 로고    scopus 로고
    • Hypoxia in abdominal aortic aneurysm supports a role for HIF-1α and Ets-1 as drivers of matrix metalloproteinase upregulation in human aortic smooth muscle cells
    • O.J. Erdozain, S. Pegrum, and V.R. Winrow Hypoxia in abdominal aortic aneurysm supports a role for HIF-1α and Ets-1 as drivers of matrix metalloproteinase upregulation in human aortic smooth muscle cells J Vasc Res 48 2011 163
    • (2011) J Vasc Res , vol.48 , pp. 163
    • Erdozain, O.J.1    Pegrum, S.2    Winrow, V.R.3
  • 100
    • 34347231998 scopus 로고    scopus 로고
    • NOX1 deficiency protects from aortic dissection in response to angiotensin II
    • G. Gavazzi, C. Deffert, and C. Trocme NOX1 deficiency protects from aortic dissection in response to angiotensin II Hypertension 50 2007 189
    • (2007) Hypertension , vol.50 , pp. 189
    • Gavazzi, G.1    Deffert, C.2    Trocme, C.3
  • 101
    • 36549085160 scopus 로고    scopus 로고
    • Control of matrix metalloproteinase catalytic activity
    • H.J. Ra, and W.C. Parks Control of matrix metalloproteinase catalytic activity Matrix Biol 26 2007 587
    • (2007) Matrix Biol , vol.26 , pp. 587
    • Ra, H.J.1    Parks, W.C.2
  • 102
    • 8444243749 scopus 로고    scopus 로고
    • Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections
    • G.J. Koullias, P. Ravichandran, and D.P. Korkolis Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections Ann Thorac Surg 78 2004 2106
    • (2004) Ann Thorac Surg , vol.78 , pp. 2106
    • Koullias, G.J.1    Ravichandran, P.2    Korkolis, D.P.3
  • 103
    • 33744824533 scopus 로고    scopus 로고
    • Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection
    • G. Sangiorgi, S. Trimarchi, and A. Mauriello Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection J Cardiovasc Med (Hagerstown) 7 2006 307
    • (2006) J Cardiovasc Med (Hagerstown) , vol.7 , pp. 307
    • Sangiorgi, G.1    Trimarchi, S.2    Mauriello, A.3
  • 104
    • 1542315273 scopus 로고    scopus 로고
    • Decreased tissue inhibitor of metalloproteinase-2/matrix metalloproteinase ratio in the acute phase of aortic dissection
    • T. Manabe, K. Imoto, and K. Uchida Decreased tissue inhibitor of metalloproteinase-2/matrix metalloproteinase ratio in the acute phase of aortic dissection Surg Today 34 2004 220
    • (2004) Surg Today , vol.34 , pp. 220
    • Manabe, T.1    Imoto, K.2    Uchida, K.3
  • 105
    • 70349229787 scopus 로고    scopus 로고
    • Thoracic aortic dissection: Are matrix metalloproteinases involved?
    • X. Zhang, Y.H. Shen, and S.A. LeMaire Thoracic aortic dissection: are matrix metalloproteinases involved? Vascular 17 2009 147
    • (2009) Vascular , vol.17 , pp. 147
    • Zhang, X.1    Shen, Y.H.2    Lemaire, S.A.3
  • 106
    • 36248940276 scopus 로고    scopus 로고
    • Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection
    • S. Peng, A. Larsson, and E. Wassberg Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection Lab Invest 87 2007 1195
    • (2007) Lab Invest , vol.87 , pp. 1195
    • Peng, S.1    Larsson, A.2    Wassberg, E.3
  • 107
    • 42549132541 scopus 로고    scopus 로고
    • Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9
    • A.W. Chung, H.H. Yang, and M.W. Radomski Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9 Circ Res 102 2008 e73
    • (2008) Circ Res , vol.102 , pp. 73
    • Chung, A.W.1    Yang, H.H.2    Radomski, M.W.3
  • 108
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor β in human disease
    • G.C. Blobe, W.P. Schiemann, and H.F. Lodish Role of transforming growth factor β in human disease N Engl J Med 342 2000 1350
    • (2000) N Engl J Med , vol.342 , pp. 1350
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 109
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • J. Massague The transforming growth factor-β family Annu Rev Cell Biol 6 1990 597
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597
    • Massague, J.1
  • 110
    • 65449146692 scopus 로고    scopus 로고
    • Absence of TGFβ signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm
    • B. Choudhary, J. Zhou, and P. Li Absence of TGFβ signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm Genesis 47 2009 115
    • (2009) Genesis , vol.47 , pp. 115
    • Choudhary, B.1    Zhou, J.2    Li, P.3
  • 111
    • 84868200856 scopus 로고    scopus 로고
    • Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm
    • A.J. Doyle, J.J. Doyle, and S.L. Bessling Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm Nat Genet 44 2012 1249
    • (2012) Nat Genet , vol.44 , pp. 1249
    • Doyle, A.J.1    Doyle, J.J.2    Bessling, S.L.3
  • 112
    • 68549123472 scopus 로고    scopus 로고
    • New regulatory mechanisms of TGF-β receptor function
    • J.S. Kang, C. Liu, and R. Derynck New regulatory mechanisms of TGF-β receptor function Trends Cell Biol 19 2009 385
    • (2009) Trends Cell Biol , vol.19 , pp. 385
    • Kang, J.S.1    Liu, C.2    Derynck, R.3
  • 113
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
    • H. Hayashi, S. Abdollah, and Y. Qiu The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling Cell 89 1997 1165
    • (1997) Cell , vol.89 , pp. 1165
    • Hayashi, H.1    Abdollah, S.2    Qiu, Y.3
  • 114
    • 0030611757 scopus 로고    scopus 로고
    • Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
    • A. Nakao, M. Afrakhte, and A. Moren Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling Nature 389 1997 631
    • (1997) Nature , vol.389 , pp. 631
    • Nakao, A.1    Afrakhte, M.2    Moren, A.3
  • 116
    • 78449269819 scopus 로고    scopus 로고
    • The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-β type i receptor
    • N. Ferrand, A. Atfi, and C. Prunier The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-β type I receptor Cancer Res 70 2010 8457
    • (2010) Cancer Res , vol.70 , pp. 8457
    • Ferrand, N.1    Atfi, A.2    Prunier, C.3
  • 117
    • 0842281496 scopus 로고    scopus 로고
    • Ski and SnoN: Negative regulators of TGF-β signaling
    • K. Luo Ski and SnoN: negative regulators of TGF-β signaling Curr Opin Genet Dev 14 2004 65
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 65
    • Luo, K.1
  • 118
    • 0033200361 scopus 로고    scopus 로고
    • The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling
    • K. Luo, S.L. Stroschein, and W. Wang The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling Genes Dev 13 1999 2196
    • (1999) Genes Dev , vol.13 , pp. 2196
    • Luo, K.1    Stroschein, S.L.2    Wang, W.3
  • 119
    • 0033595704 scopus 로고    scopus 로고
    • Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein
    • S.L. Stroschein, W. Wang, and S. Zhou Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein Science 286 1999 771
    • (1999) Science , vol.286 , pp. 771
    • Stroschein, S.L.1    Wang, W.2    Zhou, S.3
  • 120
    • 24644513885 scopus 로고    scopus 로고
    • Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-β signaling by sequestration of the Smad proteins
    • A.R. Krakowski, J. Laboureau, and A. Mauviel Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-β signaling by sequestration of the Smad proteins Proc Natl Acad Sci U S A 102 2005 12437
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 12437
    • Krakowski, A.R.1    Laboureau, J.2    Mauviel, A.3
  • 121
    • 0033521032 scopus 로고    scopus 로고
    • C-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads
    • S. Akiyoshi, H. Inoue, and J. Hanai c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads J Biol Chem 274 1999 35269
    • (1999) J Biol Chem , vol.274 , pp. 35269
    • Akiyoshi, S.1    Inoue, H.2    Hanai, J.3
  • 122
    • 34249735834 scopus 로고    scopus 로고
    • Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-β signaling
    • W. Chen, S.S. Lam, and H. Srinath Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-β signaling J Biol Chem 282 2007 11365
    • (2007) J Biol Chem , vol.282 , pp. 11365
    • Chen, W.1    Lam, S.S.2    Srinath, H.3
  • 123
    • 58149239731 scopus 로고    scopus 로고
    • Ski and SnoN, potent negative regulators of TGF-β signaling
    • J. Deheuninck, and K. Luo Ski and SnoN, potent negative regulators of TGF-β signaling Cell Res 19 2009 47
    • (2009) Cell Res , vol.19 , pp. 47
    • Deheuninck, J.1    Luo, K.2
  • 124
    • 34548386720 scopus 로고    scopus 로고
    • TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
    • M.K. Lee, C. Pardoux, and M.C. Hall TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA EMBO J 26 2007 3957
    • (2007) EMBO J , vol.26 , pp. 3957
    • Lee, M.K.1    Pardoux, C.2    Hall, M.C.3
  • 125
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-β signaling
    • Y.E. Zhang Non-Smad pathways in TGF-β signaling Cell Res 19 2009 128
    • (2009) Cell Res , vol.19 , pp. 128
    • Zhang, Y.E.1
  • 126
    • 79954625123 scopus 로고    scopus 로고
    • Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice
    • T.M. Holm, J.P. Habashi, and J.J. Doyle Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice Science 332 2011 358
    • (2011) Science , vol.332 , pp. 358
    • Holm, T.M.1    Habashi, J.P.2    Doyle, J.J.3
  • 127
    • 79956330132 scopus 로고    scopus 로고
    • Lessons on the pathogenesis of aneurysm from heritable conditions
    • M.E. Lindsay, and H.C. Dietz Lessons on the pathogenesis of aneurysm from heritable conditions Nature 473 2011 308
    • (2011) Nature , vol.473 , pp. 308
    • Lindsay, M.E.1    Dietz, H.C.2
  • 128
    • 51249117837 scopus 로고    scopus 로고
    • Newly developed angiotensin II-infused experimental models in vascular biology
    • Z. Qin Newly developed angiotensin II-infused experimental models in vascular biology Regul Pept 150 2008 1
    • (2008) Regul Pept , vol.150 , pp. 1
    • Qin, Z.1
  • 129
    • 2342570867 scopus 로고    scopus 로고
    • Angiotensin II-mediated development of vascular diseases
    • A. Daugherty, and L. Cassis Angiotensin II-mediated development of vascular diseases Trends Cardiovasc Med 14 2004 117
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 117
    • Daugherty, A.1    Cassis, L.2
  • 130
    • 79954579275 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    • J.P. Habashi, J.J. Doyle, and T.M. Holm Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism Science 332 2011 361
    • (2011) Science , vol.332 , pp. 361
    • Habashi, J.P.1    Doyle, J.J.2    Holm, T.M.3
  • 131
    • 0034129997 scopus 로고    scopus 로고
    • Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
    • A. Daugherty, M.W. Manning, and L.A. Cassis Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice J Clin Invest 105 2000 1605
    • (2000) J Clin Invest , vol.105 , pp. 1605
    • Daugherty, A.1    Manning, M.W.2    Cassis, L.A.3
  • 132
    • 0042691721 scopus 로고    scopus 로고
    • Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice
    • K. Saraff, F. Babamusta, and L.A. Cassis Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice Arterioscler Thromb Vasc Biol 23 2003 1621
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1621
    • Saraff, K.1    Babamusta, F.2    Cassis, L.A.3
  • 133
    • 33645672459 scopus 로고    scopus 로고
    • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
    • J.P. Habashi, D.P. Judge, and T.M. Holm Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome Science 312 2006 117
    • (2006) Science , vol.312 , pp. 117
    • Habashi, J.P.1    Judge, D.P.2    Holm, T.M.3
  • 134
    • 70149111035 scopus 로고    scopus 로고
    • Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement
    • N.Y. Tan, J.M. Li, and R. Stocker Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement Circ Res 105 2009 422
    • (2009) Circ Res , vol.105 , pp. 422
    • Tan, N.Y.1    Li, J.M.2    Stocker, R.3
  • 135
    • 0026514860 scopus 로고
    • Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm
    • Y. Nakashima, and K. Sueishi Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm Am J Pathol 140 1992 959
    • (1992) Am J Pathol , vol.140 , pp. 959
    • Nakashima, Y.1    Sueishi, K.2
  • 136
    • 0036781239 scopus 로고    scopus 로고
    • An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents β-aminopropionitrile monofumarate-induced aortic dissection in rats
    • H. Nagashima, K. Uto, and Y. Sakomura An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents β-aminopropionitrile monofumarate-induced aortic dissection in rats J Vasc Surg 36 2002 818
    • (2002) J Vasc Surg , vol.36 , pp. 818
    • Nagashima, H.1    Uto, K.2    Sakomura, Y.3
  • 137
    • 0041571950 scopus 로고    scopus 로고
    • Aortic dissection: New frontiers in diagnosis and management. Part I: From etiology to diagnostic strategies
    • C.A. Nienaber, and K.A. Eagle Aortic dissection: new frontiers in diagnosis and management. Part I: from etiology to diagnostic strategies Circulation 108 2003 628
    • (2003) Circulation , vol.108 , pp. 628
    • Nienaber, C.A.1    Eagle, K.A.2
  • 138
    • 33947515369 scopus 로고    scopus 로고
    • Acute aortic dissection
    • E.M. Siegal Acute aortic dissection J Hosp Med 1 2006 94
    • (2006) J Hosp Med , vol.1 , pp. 94
    • Siegal, E.M.1
  • 139
    • 79451475474 scopus 로고    scopus 로고
    • Epidemiology of thoracic aortic dissection
    • S.A. LeMaire, and L. Russell Epidemiology of thoracic aortic dissection Nat Rev Cardiol 8 2011 103
    • (2011) Nat Rev Cardiol , vol.8 , pp. 103
    • Lemaire, S.A.1    Russell, L.2
  • 140
    • 1242336791 scopus 로고    scopus 로고
    • Role of aortic root motion in the pathogenesis of aortic dissection
    • C.J. Beller, M.R. Labrosse, and M.J. Thubrikar Role of aortic root motion in the pathogenesis of aortic dissection Circulation 109 2004 763
    • (2004) Circulation , vol.109 , pp. 763
    • Beller, C.J.1    Labrosse, M.R.2    Thubrikar, M.J.3
  • 141
    • 43249122282 scopus 로고    scopus 로고
    • Ascending aortic curvature as an independent risk factor for type A dissection, and ascending aortic aneurysm formation: A mathematical model
    • M.P. Poullis, R. Warwick, and A. Oo Ascending aortic curvature as an independent risk factor for type A dissection, and ascending aortic aneurysm formation: a mathematical model Eur J Cardiothorac Surg 33 2008 995
    • (2008) Eur J Cardiothorac Surg , vol.33 , pp. 995
    • Poullis, M.P.1    Warwick, R.2    Oo, A.3
  • 142
    • 33746083553 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases, their tissue inhibitors, and osteopontin in the wall of thoracic and abdominal aortas with dilatative pathology
    • V. Lesauskaite, M.C. Epistolato, and M. Castagnini Expression of matrix metalloproteinases, their tissue inhibitors, and osteopontin in the wall of thoracic and abdominal aortas with dilatative pathology Hum Pathol 37 2006 1076
    • (2006) Hum Pathol , vol.37 , pp. 1076
    • Lesauskaite, V.1    Epistolato, M.C.2    Castagnini, M.3
  • 143
    • 0021332547 scopus 로고
    • Risk factors for aortic dissection: A necropsy study of 161 cases
    • E.W. Larson, and W.D. Edwards Risk factors for aortic dissection: a necropsy study of 161 cases Am J Cardiol 53 1984 849
    • (1984) Am J Cardiol , vol.53 , pp. 849
    • Larson, E.W.1    Edwards, W.D.2
  • 144
    • 33744817949 scopus 로고    scopus 로고
    • Familial thoracic aortic aneurysms and dissections: Three families with early-onset ascending and descending aortic dissections in women
    • V. Tran-Fadulu, J.H. Chen, and D. Lemuth Familial thoracic aortic aneurysms and dissections: three families with early-onset ascending and descending aortic dissections in women Am J Med Genet A 140 2006 1196
    • (2006) Am J Med Genet A , vol.140 , pp. 1196
    • Tran-Fadulu, V.1    Chen, J.H.2    Lemuth, D.3
  • 145
    • 0033988834 scopus 로고    scopus 로고
    • Extracellular matrix of the human aortic media: An ultrastructural histochemical and immunohistochemical study of the adult aortic media
    • K.P. Dingemans, P. Teeling, and J.H. Lagendijk Extracellular matrix of the human aortic media: an ultrastructural histochemical and immunohistochemical study of the adult aortic media Anat Rec 258 2000 1
    • (2000) Anat Rec , vol.258 , pp. 1
    • Dingemans, K.P.1    Teeling, P.2    Lagendijk, J.H.3
  • 146
    • 0017349166 scopus 로고
    • Histologic changes in the normal aging aorta: Implications for dissecting aortic aneurysm
    • T.J. Schlatmann, and A.E. Becker Histologic changes in the normal aging aorta: implications for dissecting aortic aneurysm Am J Cardiol 39 1977 13
    • (1977) Am J Cardiol , vol.39 , pp. 13
    • Schlatmann, T.J.1    Becker, A.E.2
  • 147
    • 63049096869 scopus 로고    scopus 로고
    • Circumferential and longitudinal cyclic strain of the human thoracic aorta: Age-related changes
    • T.M. Morrison, G. Choi, and C.K. Zarins Circumferential and longitudinal cyclic strain of the human thoracic aorta: age-related changes J Vasc Surg 49 2009 1029
    • (2009) J Vasc Surg , vol.49 , pp. 1029
    • Morrison, T.M.1    Choi, G.2    Zarins, C.K.3
  • 148
    • 0041662025 scopus 로고    scopus 로고
    • Aortic dissection: New frontiers in diagnosis and management. Part II: Therapeutic management and follow-up
    • C.A. Nienaber, and K.A. Eagle Aortic dissection: new frontiers in diagnosis and management. Part II: therapeutic management and follow-up Circulation 108 2003 772
    • (2003) Circulation , vol.108 , pp. 772
    • Nienaber, C.A.1    Eagle, K.A.2
  • 149
    • 34548492940 scopus 로고    scopus 로고
    • Acute aortic dissection associated with use of cocaine
    • J.C. Daniel, T.T. Huynh, and W. Zhou Acute aortic dissection associated with use of cocaine J Vasc Surg 46 2007 427
    • (2007) J Vasc Surg , vol.46 , pp. 427
    • Daniel, J.C.1    Huynh, T.T.2    Zhou, W.3
  • 150
    • 5144232338 scopus 로고    scopus 로고
    • Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: Possible relationship to aortic dissection, atherosclerosis, and hypertension
    • J. Su, J. Li, and W. Li Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension Int J Toxicol 23 2004 233
    • (2004) Int J Toxicol , vol.23 , pp. 233
    • Su, J.1    Li, J.2    Li, W.3
  • 151
    • 33645739648 scopus 로고    scopus 로고
    • VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection)
    • Y. Wang, W. Zhang, and Y. Zhang VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection) Circulation 113 2006 1615
    • (2006) Circulation , vol.113 , pp. 1615
    • Wang, Y.1    Zhang, W.2    Zhang, Y.3
  • 152
    • 0025101012 scopus 로고
    • Dissecting aneurysm: A clinicopathologic and histopathologic study of 111 autopsied cases
    • Y. Nakashima, T. Kurozumi, and K. Sueishi Dissecting aneurysm: a clinicopathologic and histopathologic study of 111 autopsied cases Hum Pathol 21 1990 291
    • (1990) Hum Pathol , vol.21 , pp. 291
    • Nakashima, Y.1    Kurozumi, T.2    Sueishi, K.3
  • 153
    • 47349103031 scopus 로고    scopus 로고
    • Polymyalgia rheumatica and giant-cell arteritis
    • C. Salvarani, F. Cantini, and G.G. Hunder Polymyalgia rheumatica and giant-cell arteritis Lancet 372 2008 234
    • (2008) Lancet , vol.372 , pp. 234
    • Salvarani, C.1    Cantini, F.2    Hunder, G.G.3
  • 154
    • 60249085947 scopus 로고    scopus 로고
    • Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS)
    • J.J. Maleszewski, D.V. Miller, and J. Lu Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS) Am J Surg Pathol 33 2009 194
    • (2009) Am J Surg Pathol , vol.33 , pp. 194
    • Maleszewski, J.J.1    Miller, D.V.2    Lu, J.3
  • 155
    • 33745917727 scopus 로고    scopus 로고
    • Ultrastructural pathology of aortic dissections in patients with Marfan syndrome: Comparison with dissections in patients without Marfan syndrome
    • K.P. Dingemans, P. Teeling, and A.C. van der Wal Ultrastructural pathology of aortic dissections in patients with Marfan syndrome: comparison with dissections in patients without Marfan syndrome Cardiovasc Pathol 15 2006 203
    • (2006) Cardiovasc Pathol , vol.15 , pp. 203
    • Dingemans, K.P.1    Teeling, P.2    Van Der Wal, A.C.3
  • 157
    • 34248232929 scopus 로고    scopus 로고
    • Genetic testing in patients with aortic aneurysms/dissections: A novel genotype/phenotype correlation?
    • S. Waldmuller, M. Muller, and H. Warnecke Genetic testing in patients with aortic aneurysms/dissections: a novel genotype/phenotype correlation? Eur J Cardiothorac Surg 31 2007 970
    • (2007) Eur J Cardiothorac Surg , vol.31 , pp. 970
    • Waldmuller, S.1    Muller, M.2    Warnecke, H.3
  • 158
    • 80053385386 scopus 로고    scopus 로고
    • Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1
    • S.A. LeMaire, M.L. McDonald, and D.C. Guo Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1 Nat Genet 43 2011 996
    • (2011) Nat Genet , vol.43 , pp. 996
    • Lemaire, S.A.1    McDonald, M.L.2    Guo, D.C.3
  • 159
    • 0035910615 scopus 로고    scopus 로고
    • Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome
    • T.E. Bunton, N.J. Biery, and L. Myers Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome Circ Res 88 2001 37
    • (2001) Circ Res , vol.88 , pp. 37
    • Bunton, T.E.1    Biery, N.J.2    Myers, L.3
  • 160
    • 31444435411 scopus 로고    scopus 로고
    • A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: Biochemical and computational analysis
    • P. Booms, A. Ney, and F. Barthel A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis J Mol Cell Cardiol 40 2006 234
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 234
    • Booms, P.1    Ney, A.2    Barthel, F.3
  • 161
    • 77955297956 scopus 로고    scopus 로고
    • In vivo studies of mutant fibrillin-1 microfibrils
    • N.L. Charbonneau, E.J. Carlson, and S. Tufa In vivo studies of mutant fibrillin-1 microfibrils J Biol Chem 285 2010 24943
    • (2010) J Biol Chem , vol.285 , pp. 24943
    • Charbonneau, N.L.1    Carlson, E.J.2    Tufa, S.3
  • 162
    • 34548437703 scopus 로고    scopus 로고
    • Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome
    • A.W. Chung, K. Au Yeung, and G.G. Sandor Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome Circ Res 101 2007 512
    • (2007) Circ Res , vol.101 , pp. 512
    • Chung, A.W.1    Au Yeung, K.2    Sandor, G.G.3
  • 163
    • 33750538682 scopus 로고    scopus 로고
    • Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment
    • G. Guo, P. Booms, and M. Halushka Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment Circulation 114 2006 1855
    • (2006) Circulation , vol.114 , pp. 1855
    • Guo, G.1    Booms, P.2    Halushka, M.3
  • 164
    • 79957613541 scopus 로고    scopus 로고
    • Induction of macrophage chemotaxis by aortic extracts from patients with Marfan syndrome is related to elastin binding protein
    • G. Guo, P. Gehle, and S. Doelken Induction of macrophage chemotaxis by aortic extracts from patients with Marfan syndrome is related to elastin binding protein PLoS One 6 2011 e20138
    • (2011) PLoS One , vol.6 , pp. 20138
    • Guo, G.1    Gehle, P.2    Doelken, S.3
  • 165
    • 52949141431 scopus 로고    scopus 로고
    • Genetic basis of thoracic aortic aneurysms and dissections: Focus on smooth muscle cell contractile dysfunction
    • D.M. Milewicz, D.C. Guo, and V. Tran-Fadulu Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction Annu Rev Genomics Hum Genet 9 2008 283
    • (2008) Annu Rev Genomics Hum Genet , vol.9 , pp. 283
    • Milewicz, D.M.1    Guo, D.C.2    Tran-Fadulu, V.3
  • 166
    • 79251602475 scopus 로고    scopus 로고
    • Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis
    • I.M. van de Laar, R.A. Oldenburg, and G. Pals Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis Nat Genet 43 2011 121
    • (2011) Nat Genet , vol.43 , pp. 121
    • Van De Laar, I.M.1    Oldenburg, R.A.2    Pals, G.3
  • 167
    • 84864411184 scopus 로고    scopus 로고
    • TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome
    • C. Boileau, D.C. Guo, and N. Hanna TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome Nat Genet 44 2012 916
    • (2012) Nat Genet , vol.44 , pp. 916
    • Boileau, C.1    Guo, D.C.2    Hanna, N.3
  • 168
    • 84864415173 scopus 로고    scopus 로고
    • Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm
    • M.E. Lindsay, D. Schepers, and N.A. Bolar Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm Nat Genet 44 2012 922
    • (2012) Nat Genet , vol.44 , pp. 922
    • Lindsay, M.E.1    Schepers, D.2    Bolar, N.A.3
  • 169
    • 22044433881 scopus 로고    scopus 로고
    • The spectrum, management and clinical outcome of Ehlers-Danlos syndrome type IV: A 30-year experience
    • G.S. Oderich, J.M. Panneton, and T.C. Bower The spectrum, management and clinical outcome of Ehlers-Danlos syndrome type IV: a 30-year experience J Vasc Surg 42 2005 98
    • (2005) J Vasc Surg , vol.42 , pp. 98
    • Oderich, G.S.1    Panneton, J.M.2    Bower, T.C.3
  • 170
    • 0036873192 scopus 로고    scopus 로고
    • Genetic basis of thoracic aortic aneurysms and dissections
    • S.N. Hasham, D.C. Guo, and D.M. Milewicz Genetic basis of thoracic aortic aneurysms and dissections Curr Opin Cardiol 17 2002 677
    • (2002) Curr Opin Cardiol , vol.17 , pp. 677
    • Hasham, S.N.1    Guo, D.C.2    Milewicz, D.M.3
  • 171
    • 19944432730 scopus 로고    scopus 로고
    • Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome
    • V.L. Sheen, A. Jansen, and M.H. Chen Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome Neurology 64 2005 254
    • (2005) Neurology , vol.64 , pp. 254
    • Sheen, V.L.1    Jansen, A.2    Chen, M.H.3
  • 172
    • 0031823564 scopus 로고    scopus 로고
    • Reduced penetrance and variable expressivity of familial thoracic aortic aneurysms/dissections
    • D.M. Milewicz, H. Chen, and E.S. Park Reduced penetrance and variable expressivity of familial thoracic aortic aneurysms/dissections Am J Cardiol 82 1998 474
    • (1998) Am J Cardiol , vol.82 , pp. 474
    • Milewicz, D.M.1    Chen, H.2    Park, E.S.3
  • 173
    • 37249002743 scopus 로고    scopus 로고
    • Dissection of the aorta in Turner syndrome: Two cases and review of 85 cases in the literature
    • M. Carlson, and M. Silberbach Dissection of the aorta in Turner syndrome: two cases and review of 85 cases in the literature J Med Genet 44 2007 745
    • (2007) J Med Genet , vol.44 , pp. 745
    • Carlson, M.1    Silberbach, M.2
  • 174
    • 33748752789 scopus 로고    scopus 로고
    • Familial thoracic aortic aneurysms and dissections - Incidence, modes of inheritance, and phenotypic patterns
    • G. Albornoz, M.A. Coady, and M. Roberts Familial thoracic aortic aneurysms and dissections - incidence, modes of inheritance, and phenotypic patterns Ann Thorac Surg 82 2006 1400
    • (2006) Ann Thorac Surg , vol.82 , pp. 1400
    • Albornoz, G.1    Coady, M.A.2    Roberts, M.3
  • 175
    • 0030946538 scopus 로고    scopus 로고
    • Familial thoracic aortic dilatations and dissections: A case control study
    • A. Biddinger, M. Rocklin, and J. Coselli Familial thoracic aortic dilatations and dissections: a case control study J Vasc Surg 25 1997 506
    • (1997) J Vasc Surg , vol.25 , pp. 506
    • Biddinger, A.1    Rocklin, M.2    Coselli, J.3
  • 176
    • 33644627494 scopus 로고    scopus 로고
    • Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus
    • L. Zhu, R. Vranckx, and P. Khau Van Kien Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus Nat Genet 38 2006 343
    • (2006) Nat Genet , vol.38 , pp. 343
    • Zhu, L.1    Vranckx, R.2    Khau Van Kien, P.3
  • 177
    • 0035933045 scopus 로고    scopus 로고
    • Familial thoracic aortic aneurysms and dissections: Genetic heterogeneity with a major locus mapping to 5q13-14
    • D. Guo, S. Hasham, and S.Q. Kuang Familial thoracic aortic aneurysms and dissections: genetic heterogeneity with a major locus mapping to 5q13-14 Circulation 103 2001 2461
    • (2001) Circulation , vol.103 , pp. 2461
    • Guo, D.1    Hasham, S.2    Kuang, S.Q.3
  • 178
    • 36549071997 scopus 로고    scopus 로고
    • Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections
    • D.C. Guo, H. Pannu, and V. Tran-Fadulu Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections Nat Genet 39 2007 1488
    • (2007) Nat Genet , vol.39 , pp. 1488
    • Guo, D.C.1    Pannu, H.2    Tran-Fadulu, V.3
  • 179
    • 0038755597 scopus 로고    scopus 로고
    • Mapping a locus for familial thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25
    • S.N. Hasham, M.C. Willing, and D.C. Guo Mapping a locus for familial thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25 Circulation 107 2003 3184
    • (2003) Circulation , vol.107 , pp. 3184
    • Hasham, S.N.1    Willing, M.C.2    Guo, D.C.3
  • 180
    • 0041842607 scopus 로고    scopus 로고
    • Candidate locus analysis of familial ascending aortic aneurysms and dissections confirms the linkage to the chromosome 5q13-14 in Finnish families
    • S. Kakko, T. Raisanen, and M. Tamminen Candidate locus analysis of familial ascending aortic aneurysms and dissections confirms the linkage to the chromosome 5q13-14 in Finnish families J Thorac Cardiovasc Surg 126 2003 106
    • (2003) J Thorac Cardiovasc Surg , vol.126 , pp. 106
    • Kakko, S.1    Raisanen, T.2    Tamminen, M.3
  • 181
    • 23044438103 scopus 로고    scopus 로고
    • Mutations in transforming growth factor-β receptor type II cause familial thoracic aortic aneurysms and dissections
    • H. Pannu, V.T. Fadulu, and J. Chang Mutations in transforming growth factor-β receptor type II cause familial thoracic aortic aneurysms and dissections Circulation 112 2005 513
    • (2005) Circulation , vol.112 , pp. 513
    • Pannu, H.1    Fadulu, V.T.2    Chang, J.3
  • 182
    • 0035933002 scopus 로고    scopus 로고
    • Identification of a chromosome 11q23.2-q24 locus for familial aortic aneurysm disease, a genetically heterogeneous disorder
    • C.J. Vaughan, M. Casey, and J. He Identification of a chromosome 11q23.2-q24 locus for familial aortic aneurysm disease, a genetically heterogeneous disorder Circulation 103 2001 2469
    • (2001) Circulation , vol.103 , pp. 2469
    • Vaughan, C.J.1    Casey, M.2    He, J.3
  • 183
    • 0029001289 scopus 로고
    • A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection
    • U. Francke, M.A. Berg, and K. Tynan A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection Am J Hum Genet 56 1995 1287
    • (1995) Am J Hum Genet , vol.56 , pp. 1287
    • Francke, U.1    Berg, M.A.2    Tynan, K.3
  • 186
    • 84863477505 scopus 로고    scopus 로고
    • + fibronectin in the extracellular matrix of defective Ehlers-Danlos syndrome fibroblasts
    • + fibronectin in the extracellular matrix of defective Ehlers-Danlos syndrome fibroblasts Biochim Biophys Acta 1820 2012 1576
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 1576
    • Zoppi, N.1    Ritelli, M.2    Colombi, M.3
  • 187
    • 33748079591 scopus 로고    scopus 로고
    • Expression of distinct classes of titin isoforms in striated and smooth muscles by alternative splicing, and their conserved interaction with filamins
    • S. Labeit, S. Lahmers, and C. Burkart Expression of distinct classes of titin isoforms in striated and smooth muscles by alternative splicing, and their conserved interaction with filamins J Mol Biol 362 2006 664
    • (2006) J Mol Biol , vol.362 , pp. 664
    • Labeit, S.1    Lahmers, S.2    Burkart, C.3
  • 188
    • 0027968934 scopus 로고
    • Characterization of the actin binding site on smooth muscle filamin
    • M.C. Lebart, C. Mejean, and D. Casanova Characterization of the actin binding site on smooth muscle filamin J Biol Chem 269 1994 4279
    • (1994) J Biol Chem , vol.269 , pp. 4279
    • Lebart, M.C.1    Mejean, C.2    Casanova, D.3
  • 189
    • 40949119063 scopus 로고    scopus 로고
    • Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells
    • N. Yu, L. Erb, and R. Shivaji Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells Circ Res 102 2008 581
    • (2008) Circ Res , vol.102 , pp. 581
    • Yu, N.1    Erb, L.2    Shivaji, R.3
  • 190
    • 17644382625 scopus 로고    scopus 로고
    • Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart
    • K.L. Waldo, M.R. Hutson, and C.C. Ward Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart Dev Biol 281 2005 78
    • (2005) Dev Biol , vol.281 , pp. 78
    • Waldo, K.L.1    Hutson, M.R.2    Ward, C.C.3
  • 191
    • 34249289023 scopus 로고    scopus 로고
    • Developmental basis of vascular smooth muscle diversity
    • M.W. Majesky Developmental basis of vascular smooth muscle diversity Arterioscler Thromb Vasc Biol 27 2007 1248
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1248
    • Majesky, M.W.1
  • 192
    • 1842338876 scopus 로고    scopus 로고
    • Smooth muscle lineage diversity in the chick embryo: Two types of aortic smooth muscle cell differ in growth and receptor-mediated transcriptional responses to transforming growth factor-β
    • S. Topouzis, and M.W. Majesky Smooth muscle lineage diversity in the chick embryo: two types of aortic smooth muscle cell differ in growth and receptor-mediated transcriptional responses to transforming growth factor-β Dev Biol 178 1996 430
    • (1996) Dev Biol , vol.178 , pp. 430
    • Topouzis, S.1    Majesky, M.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.