Mice with a Deletion in the First Intron of the Col1a1 Gene Develop Age-Dependent Aortic Dissection and Rupture

Circulation Research

Volumn 94, Issue 1, 2004, Pages 83-90

  Rahkonen, Otto ^a   Su, Ming ^b   Hakovirta, Harri ^a   Koskivirta, Ilpo ^a   Hormuzdi, Sheriar G ^c,d   Vuorio, Eero ^a   Bornstein, Paul ^c   Penttinen, Risto ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF WASHINGTON   (United States)

^d The Department of Neurology   (Germany)

Author keywords

Collagen; Gene regulation; Homologous recombination; RT PCR; Targeted mutation

Indexed keywords

COLLAGEN TYPE 1; COMPLEMENTARY DNA; MESSENGER RNA;

AGE; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA DISSECTION; AORTA RUPTURE; ARTICLE; AUTOPSY; COL1A1 GENE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE; GENE AMPLIFICATION; GENETIC PREDISPOSITION; HETEROZYGOSITY; HOMOZYGOSITY; INTRON; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN CONTENT; RNA ANALYSIS;

AGE FACTORS; ANEURYSM, DISSECTING; ANIMALS; AORTA; AORTIC RUPTURE; COLLAGEN; COLLAGEN TYPE I; FIBRILLAR COLLAGENS; HYDROXYPROLINE; INTRONS; MICE; RNA, MESSENGER; SEQUENCE DELETION; SURVIVAL ANALYSIS;

EID: 0346059549     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000108263.74520.15     Document Type: Article

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