ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections

Annals of Thoracic Surgery

Volumn 95, Issue 2, 2013, Pages 570-577

  Ren, Pingping ^a,b,d   Zhang, Lin ^a,c   Xu, Gaiping ^a,c   Palmero, Laura C ^a,c   Albini, Paul T ^a,c   Coselli, Joseph S ^a,c   Shen, Ying H ^a,c   Lemaire, Scott A ^a,b,c  

^a MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c ST LUKE S EPISCOPAL HOSPITAL   (United States)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS1 PROTEIN; AGGRECANASE 1; MESSENGER RNA; PROTEOGLYCAN; TRANSFORMING GROWTH FACTOR BETA; VERSICAN;

ADULT; AGED; AORTA ANEURYSM; AORTA DISSECTION; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DESCENDING AORTA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MACROPHAGE; MALE; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; STAINING; UPREGULATION;

EID: 84872788994     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2012.10.084     Document Type: Article

References (35)

1. K.D. Kochanek, J.Q. Xu, S.L. Murphy, A.M. Miniño, H.-C. Kung Deaths: final data for 2009 National Vital Statistics Reports; vol 60 no 3 2011 National Center for Health Statistics Hyattsville, MD
2. M.J. Davies Aortic aneurysm formation: lessons from human studies and experimental models Circulation 98 1998 193 195
3. K. Kuno, N. Kanada, E. Nakashima, F. Fujiki, F. Ichimura, K. Matsushima Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene J Biol Chem 272 1997 556 562
4. R.C. Salter, T.G. Ashlin, A.P. Kwan, D.P. Ramji ADAMTS proteases: key roles in atherosclerosis? J Mol Med (Berl) 88 2010 1203 1211
5. J.D. Sandy, J. Westling, R.D. Kenagy Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4 J Biol Chem 276 2001 13372 13378
6. C. Gendron, M. Kashiwagi, N.H. Lim Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4 J Biol Chem 282 2007 18294 18306
7. A.X. Torres-Collado, W. Kisiel, M.L. Iruela-Arispe, J.C. Rodriguez-Manzaneque ADAMTS1 interacts with, cleaves, and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2 J Biol Chem 281 2006 17827 17837
8. A. Luque, D.R. Carpizo, M.L. Iruela-Arispe ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165 J Biol Chem 278 2003 23656 23665
9. M. Krampert, S. Kuenzle, S.N. Thai, N. Lee, M.L. Iruela-Arispe, S. Werner ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells J Biol Chem 280 2005 23844 23852
10. T. Taketani, Y. Imai, T. Morota Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens Int Heart J 46 2005 265 277
11. A.C. Jönsson-Rylander, T. Nilsson, R. Fritsche-Danielson Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican Arterioscler Thromb Vasc Biol 25 2005 180 185
12. D. Wågsäter, H. Björk, C. Zhu ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques Atherosclerosis 196 2008 514 522
13. R.D. Kenagy, S.K. Min, E. Mulvihill, A.W. Clowes A link between smooth muscle cell death and extracellular matrix degradation during vascular atrophy J Vasc Surg 54 2011 182 191.e24
14. M.S. Sabatine, L. Ploughman, K.L. Simonsen Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy Arterioscler Thromb Vasc Biol 28 2008 562 567
15. K. Shimizu, R.N. Mitchell, P. Libby Inflammation and cellular immune responses in abdominal aortic aneurysms Arterioscler Thromb Vasc Biol 26 2006 987 994
16. J.M. Lemire, K.R. Braun, P. Maurel, E.D. Kaplan, S.M. Schwartz, T.N. Wight Versican/PG-M isoforms in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 19 1999 1630 1639
17. R.G. LeBaron, D.R. Zimmermann, E. Ruoslahti Hyaluronate binding properties of versican J Biol Chem 267 1992 10003 10010
18. M.J. Merrilees, J.M. Lemire, J.W. Fischer Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury Circ Res 90 2002 481 487
19. A. Hinek, K.R. Braun, K. Liu, Y. Wang, T.N. Wight Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients Am J Pathol 164 2004 119 131
20. R. Huang, M.J. Merrilees, K. Braun Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury Circ Res 98 2006 370 377
21. W. Sheng, G. Wang, Y. Wang The roles of versican V1 and V2 isoforms in cell proliferation and apoptosis Mol Biol Cell 16 2005 1330 1340
22. D.P. LaPierre, D.Y. Lee, S.Z. Li The ability of versican to simultaneously cause apoptotic resistance and sensitivity Cancer Res 67 2007 4742 4750
23. Y. Zhang, L. Cao, B.L. Yang, B.B. Yang The G3 domain of versican enhances cell proliferation via epidermial growth factor-like motifs J Biol Chem 273 1998 21342 21351
24. C. Ricciardelli, D.L. Russell, M.P. Ween Formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility J Biol Chem 282 2007 10814 10825
25. S. Dutt, M. Kléber, M. Matasci, L. Sommer, D.R. Zimmermann Versican V0 and V1 guide migratory neural crest cells J Biol Chem 281 2006 12123 12131
26. S.P. Evanko, J.C. Angello, T.N. Wight Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells Arterioscler Thromb Vasc Biol 19 1999 1004 1013
27. J.M. Lemire, M.J. Merrilees, K.R. Braun, T.N. Wight Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro J Cell Physiol 190 2002 38 45
28. R.D. Kenagy, A.H. Plaas, T.N. Wight Versican degradation and vascular disease Trends Cardiovasc Med 16 2006 209 215
29. A.D. Theocharis, I. Tsolakis, A. Hjerpe, N.K. Karamanos Versican undergoes specific alterations in the fine molecular structure and organization in human aneurysmal abdominal aortas Biomed Chromatogr 17 2003 411 416
30. L. Pulkkinen, K. Kainulainen, T. Krusius Deficient expression of the gene coding for decorin in a lethal form of Marfan syndrome J Biol Chem 265 1990 17780 17785
31. A.M. Heegaard, A. Corsi, C.C. Danielsen Biglycan deficiency causes spontaneous aortic dissection and rupture in mice Circulation 115 2007 2731 2738
32. M.D. Tortorella, E.C. Arner, R. Hills Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes J Biol Chem 279 2004 17554 17561
33. R. Hills, R. Mazzarella, K. Fok Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate J Biol Chem 282 2007 11101 11109
34. M. Kashiwagi, J.J. Enghild, C. Gendron Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing J Biol Chem 279 2004 10109 10119
35. R.D. Kenagy, S.K. Min, A.W. Clowes, J.D. Sandy Cell death-associated ADAMTS4 and versican degradation in vascular tissue J Histochem Cytochem 57 2009 889 897