Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice

Circulation

Volumn 106, Issue 19, 2002, Pages 2503-2509

  Mäki, Joni M ^a   Räsänen, Juha ^a   Tikkanen, Hilkka ^a   Sormunen, Raija ^a   Mäkikallio, Kaarin ^a   Kivirikko, Kari I ^a   Soininen, Raija ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Aneurysm; Aorta; Crosslink; Lysyl oxidase

Indexed keywords

ISOENZYME; PROTEIN LYSINE 6 OXIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA ANEURYSM; AORTA WALL; ARTERY WALL; ARTICLE; AUTOPSY; BLOOD FLOW VELOCITY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR SYSTEM; DESCENDING AORTA; DOPPLER FLOWMETRY; DUCTUS VENOSUS; ELASTIC FIBER; ELECTRON MICROSCOPY; FETUS; GENE; GENE ACTIVITY; GENE INACTIVATION; IMPEDANCE; LAMELLAR BODY; LOX GENE; MICROSCOPY; MOUSE; NEWBORN; NONHUMAN; ORGANOGENESIS; PERINATAL DEATH; PREGNANCY; PRIORITY JOURNAL; SMOOTH MUSCLE; UMBILICAL ARTERY;

ANIMALS; ANIMALS, NEWBORN; AORTA; AORTIC ANEURYSM; BLOOD FLOW VELOCITY; CARDIOVASCULAR ABNORMALITIES; CARDIOVASCULAR DISEASES; FETAL DISEASES; FETAL VIABILITY; GENE TARGETING; GENES, LETHAL; HEART; HETEROZYGOTE; HOMOZYGOTE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MYOCARDIUM; PHENOTYPE; PROTEIN-LYSINE 6-OXIDASE; ULTRASONOGRAPHY, DOPPLER;

EID: 0037027504     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000038109.84500.1E     Document Type: Article

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