Metal complexes as inhibitors of transcription factor activity

Coordination Chemistry Reviews

Volumn 257, Issue 21-22, 2013, Pages 3139-3151

  Leung, Chung Hang ^a   He, Hong Zhang ^b   Liu, Li Juan ^a   Wang, Modi ^b   Chan, Daniel Shiu Hin ^b   Ma, Dik Lung ^b  

^a University of Macau   (Macao)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

DNA; Inhibitor; Metal complex; Protein; Transcription factor

Indexed keywords

EID: 84883515649     PISSN: 00108545     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.08.008     Document Type: Review

References (148)

1. Papavassiliou A.G. N. Engl. J. Med. 1995, 332:45-47.
2. Levine M., Tjian R. Nature 2003, 424:147-151.
3. Pabo C.O., Sauer R.T. Annu. Rev. Biochem. 1992, 61:1053-1095.
4. Latchman D.S. N. Engl. J. Med. 1996, 334:28-33.
5. Tenen D.G., Hromas R., Licht J.D., Zhang D.-E. Blood 1997, 90:489-519.
6. Costa R.H., Kalinichenko V.V., Holterman A.-X.L., Wang X. Hepatology 2003, 38:1331-1347.
7. Babu M.M., Luscombe N.M., Aravind L., Gerstein M., Teichmann S.A. Curr. Opin. Struct. Biol. 2004, 14:283-291.
8. Rosenbauer F., Tenen D.G. Nat. Rev. Immunol. 2007, 7:105-117.
9. Wang K., Wan Y.-J.Y. Exp. Biol. Med. 2008, 233:496-506.
10. Vaquerizas J.M., Kummerfeld S.K., Teichmann S.A., Luscombe N.M. Nat. Rev. Genet. 2009, 10:252-263.
11. Whitmarsh A.J., Davis R.J. Cell. Mol. Life Sci. 2000, 57:1172-1183.
12. Lee T.I., Young R.A. Annu. Rev. Genet. 2000, 34:77-137.
13. Naar A.M., Lemon B.D., Tjian R. Annu. Rev. Biochem. 2001, 70:475-501.
14. Kornberg R.D. Trends Biochem. Sci. 2005, 30:235-239.
15. Kornberg R.D. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:12955-12961.
16. Lodish H., Berk A., Zipursky S.L., Matsudaira P., Baltimore D., Darnell J. Molecular Cell Biology 2000, W.H. Freeman (Ed.).
17. Perissi V., Jepsen K., Glass C.K., Rosenfeld M.G. Nat. Rev. Genet. 2010, 11:109-123.
18. Funnell A.W., Crossley M. Homo-heterodimerization in transcriptional regulation. Protein Dimerization and Oligomerization in Biology 2012, 105-121. Springer, New York. J. Matthews (Ed.).
19. Pratap J., Lian J.B., Stein G.S. Bone 2011, 48:30-36.
20. Santiago-Walker A., Herlyn M. J. Natl. Cancer Inst. 2010, 102:1103-1104.
21. Chang H.-C., Sehra S., Goswami R., Yao W., Yu Q., Stritesky G.L., Jabeen R., McKinley C., Ahyi A.-N., Han L., Nguyen E.T., Robertson M.J., Perumal N.B., Tepper R.S., Nutt S.L., Kaplan M.H. Nat. Immunol. 2010, 11:527-534.
22. Vallabhapurapu S., Karin M. Annu. Rev. Immunol. 2009, 27:693-733.
23. Ben-Neriah Y., Karin M. Nat. Immunol. 2011, 12:715-723.
24. Crisponi L., Deiana M., Loi A., Chiappe F., Uda M., Amati P., Bisceglia L., Zelante L., Nagaraja R., Porcu S., Ristaldi M.S., Marzella R., Rocchi M., Nicolino M., Lienhardt-Roussie A., Nivelon A., Verloes A., Schlessinger D., Gasparini P., Bonneau D., Cao A., Pilia G. Nat. Genet. 2001, 27:159-166.
25. Kozlowski K., Walter M.A. Hum. Mol. Genet. 2000, 9:2131-2139.
26. Dattani M.T., Robinson I.C. Clin. Genet. 2000, 57:337-346.
27. Darnell J.E. Nat. Rev. Cancer 2002, 2:740-749.
28. Sharma R.K., Otsuka M., Gaba G., Mehta S. RSC Adv. 2013, 3:1282-1296.
29. Ho Y., Tsao S.-W., Zeng M., Lui V.W.Y. Cancer Lett. 2013, 330:141-149.
30. Neef D.W., Jaeger A.M., Thiele D.J. Nat. Rev. Drug Discov. 2011, 10:930-944.
31. Berg T. Curr. Opin. Chem. Biol. 2008, 12:464-471.
32. Arndt H.-D. Angew. Chem. Int. Ed. 2006, 45:4552-4560.
33. Handel M.L. Inflamm. Res. 1997, 46:282-286.
34. Handel M.L., DeFazio A., Watts C.K.W., Day R.O., Sutherland R.L. Mol. Pharmacol. 1991, 40:613-618.
35. Handel M.L., Watts C.K.W., DeFazio A., Day R.O., Sutherland R.L. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:4497-4501.
36. Hollywood D.P., Hurst H.C. Br. J. Cancer 1995, 71:753-757.
37. Handel M.L., Watts C.K., Day R.O., Sutherland R.L. Met. Based Drugs 1994, 1:528.
38. Handel M.L., Sivertsen S., Watts C.K.W., Day R.O., Sutherland R.L. Agents Actions Suppl. 1993, 44:219-223.
39. Majmudar C.Y., Mapp A.K. Curr. Opin. Chem. Biol. 2005, 9:467-474.
40. Koehler A.N. Curr. Opin. Chem. Biol. 2010, 14:331-340.
41. Noffke A.L., Habtemariam A., Pizarro A.M., Sadler P.J. Chem. Commun. 2012, 48:5219-5246.
42. Gasser G., Metzler-Nolte N. Curr. Opin. Chem. Biol. 2012, 16:84-91.
43. Bruijnincx P.C.A., Sadler P.J. Adv. Inorg. Chem. 2009, 61:1-62.
44. Geldmacher Y., Oleszak M., Sheldrick W.S. Inorg. Chim. Acta 2012, 393:84-102.
45. Leung C.-H., Chan D.S.-H., Ma V.P.-Y., Ma D.-L. Med. Res. Rev. 2012, 10.1002/med.21266.
46. Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X. Science 2001, 291:1304-1351.
47. Kuphal S., Palm H.G., Poser I., Bosserhoff A.K. Melanoma Res. 2005, 15:305-313.
48. Peinado H., Portillo F., Cano A. Int. J. Dev. Biol. 2004, 48:365-375.
49. Huang C.-H., Yang W.-H., Chang S.-Y., Tai S.-K., Tzeng C.-H., Kao J.-Y., Wu K.-J., Yang M.-H. Neoplasia 2009, 11:1371-1382.
50. Harney A.S., Lee J., Manus L.M., Wang P., Ballweg D.M., LaBonne C., Meade T.J. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:13667-13672.
51. Louie A.Y., Meade T.J. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6663-6668.
52. Harney A., Sole L., Meade T. J. Biol. Inorg. Chem. 2012, 17:853-860.
53. Böttcher A., Takeuchi T., Hardcastle K.I., Meade T.J., Gray H.B., Cwikel D., Kapon M., Dori Z. Inorg. Chem. 1997, 36:2498-2504.
54. Blum O., Haiek A., Cwikel D., Dori Z., Meade T.J., Gray H.B. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6659-6662.
55. Takeuchi T., Bottcher A., Quezada C.M., Meade T.J., Gray H.B. Bioorg. Med. Chem. 1999, 7:815-819.
56. Hellman L.M., Fried M.G. Nat. Protoc. 2007, 2:1849-1861.
57. Harney A.S., Meade T.J., LaBonne C. PLoS ONE 2012, 7:e32318.
58. Yang Z., Rayala S., Nguyen D., Vadlamudi R.K., Chen S., Kumar R. Cancer Res. 2005, 65:3179-3184.
59. Hurtado R.R., Harney A.S., Heffern M.C., Holbrook R.J., Holmgren R.A., Meade T.J. Mol. Pharm. 2012, 9:325-333.
60. Hooper J.E., Scott M.P. Nat. Rev. Mol. Cell Biol. 2005, 6:306-317.
61. Yauch R.L., Gould S.E., Scales S.J., Tang T., Tian H., Ahn C.P., Marshall D., Fu L., Januario T., Kallop D., Nannini-Pepe M., Kotkow K., Marsters J.C., Rubin L.L., de Sauvage F.J. Nature 2008, 455:406-410.
62. Kasper M., Regl G., Frischauf A.M., Aberger F. Eur. J. Cancer 2006, 42:437-445.
63. Safe S., Abdelrahim M. Eur. J. Cancer 2005, 41:2438-2448.
64. Marconett C.N., Sundar S.N., Tseng M., Tin A.S., Tran K.Q., Mahuron K.M., Bjeldanes L.F., Firestone G.L. Carcinogenesis 2011, 32:1315-1323.
65. Nomura T., Yamasaki M., Nomura Y., Mimata H. Oncol. Rep. 2005, 14:993-997.
66. Chen S., Xu D., Jiang H., Xi Z., Zhu P., Liu Y. Angew. Chem. Int. Ed. 2012, 51:12258-12262.
67. Min Y., Mao C.Q., Chen S., Ma G., Wang J., Liu Y. Angew. Chem. Int. Ed. 2012, 51:6742-6747.
68. Chen S., Jiang H., Wei K., Liu Y. Chem. Commun. 2013, 49:1226-1228.
69. Park G.Y., Wilson J.J., Song Y., Lippard S.J. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:11987-11992.
70. Aaronson D.S., Horvath C.M. Science 2002, 296:1653-1655.
71. Rawlings J.S., Rosler K.M., Harrison D.A. J. Cell Sci. 2004, 117:1281-1283.
72. Jatiani S.S., Baker S.J., Silverman L.R., Reddy E.P. Genes Cancer 2010, 1:979-993.
73. O'Shea J.J., Plenge R. Immunity 2012, 36:542-550.
74. Rane S.G., Reddy E.P. Oncogene 2002, 21:3334-3358.
75. Al Zaid Siddiquee K., Turkson J. Cell Res. 2008, 18:254-267.
76. Kota J., Caceres N., Constantinescu S.N. Leukemia 2008, 22:1828-1840.
77. Yu H., Pardoll D., Jove R. Nat. Rev. Cancer 2009, 9:798-809.
78. Turkson J., Zhang S., Palmer J., Kay H., Stanko J., Mora L.B., Sebti S., Yu H., Jove R. Mol. Cancer Ther. 2004, 3:1533-1542.
79. Turkson J., Zhang S., Mora L.B., Burns A., Sebti S., Jove R. J. Biol. Chem. 2005, 280:32979-32988.
80. Cleare M.J., Hughes E.G., Jacoby B., Pepys J. Clin. Exp. Allergy 1976, 6:183-195.
81. Schuppe H.-C., Kulig J., Lerchenmuller C., Becker D., Gleichmann E., Kind P. Toxicol. Lett. 1997, 93:125-133.
82. Drewry J.A., Fletcher S., Yue P., Marushchak D., Zhao W., Sharmeen S., Zhang X., Schimmer A.D., Gradinaru C., Turkson J., Gunning P.T. Chem. Commun. 2010, 46:892-894.
83. Kruppa M., Konig B. Chem. Rev. 2006, 106:3520-3560.
84. Gniazdowski M., Denny W.A., Nelson S.M., Czyz M. Expert Opin. Ther. Targets 2005, 9:471-489.
85. Dervan P.B. Bioorg. Med. Chem. 2001, 9:2215-2235.
86. Odom D.T., Parker C.S., Barton J.K. Biochemistry 1999, 38:5155-5163.
87. Keene F.R., Smith J.A., Collins J.G. Coord. Chem. Rev. 2009, 253:2021-2035.
88. Chan D.S.-H., Lee H.-M., Che C.-M., Leung C.-H., Ma D.-L. Chem. Commun. 2009, 7479-7481.
89. Man B.Y.-W., Chan D.S.-H., Yang H., Ang S.-W., Yang F., Yan S.-C., Ho C.-M., Wu P., Che C.-M., Leung C.-H., Ma D.-L. Chem. Commun. 2010, 46:8534-8536.
90. He H.-Z., Chan D.S.-H., Leung C.-H., Ma D.-L. Chem. Commun. 2012, 48:9462-9464.
91. He H.-Z., Chan D.S.-H., Leung C.-H., Ma D.-L. Nucleic Acids Res. 2013, 41:4345-4359.
92. He H.-Z., Leung K.-H., Yang H., Shiu-Hin Chan D., Leung C.-H., Zhou J., Bourdoncle A., Mergny J.-L., Ma D.-L. Biosens. Bioelectron. 2013, 41:871-874.
93. Leung K.-H., He H.-Z., Ma V.P.-Y., Chan D.S.-H., Leung C.-H., Ma D.-L. Chem. Commun. 2013, 49:771-773.
94. Leung K.-H., He H.-Z., Ma V.P.-Y., Zhong H.-J., Chan D.S.-H., Zhou J., Mergny J.-L., Leung C.-H., Ma D.-L. Chem. Commun. 2013, 49:5630-5632.
95. Ma D.-L., He H.-Z., Leung K.-H., Chan D.S.-H., Leung C.-H. Angew. Chem. Int. Ed. 2013, 52:7666-7682.
96. Ma D.-L., He H.-Z., Leung K.-H., Zhong H.-J., Chan D.S.-H., Leung C.-H. Chem. Soc. Rev. 2013, 42:3427-3440.
97. Leung C.-H., Zhong H.-J., He H.-Z., Lu L., Chan D.S.-H., Ma D.-L. Chem. Sci. 2013, 4:3781-3795.
98. Schatzschneider U., Barton J.K. J. Am. Chem. Soc. 2004, 126:8630-8631.
99. Petitjean A., Barton J.K. J. Am. Chem. Soc. 2004, 126:14728-14729.
100. Brunner J., Barton J.K. Biochemistry 2006, 45:12295-12302.
101. Hart J.R., Glebov O., Ernst R.J., Kirsch I.R., Barton J.K. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:15359-15363.
102. Zeglis B.M., Boland J.A., Barton J.K. J. Am. Chem. Soc. 2008, 130:7530-7531.
103. Zeglis B.M., Barton J.K. Inorg. Chem. 2008, 47:6452-6457.
104. Song H., Kaiser J.T., Barton J.K. Nat. Chem. 2012, 4:615-620.
105. Ernst R.J., Song H., Barton J.K. J. Am. Chem. Soc. 2009, 131:2359-2366.
106. Ernst R.J., Komor A.C., Barton J.K. Biochemistry 2011, 50:10919-10928.
107. Komor A.C., Schneider C.J., Weidmann A.G., Barton J.K. J. Am. Chem. Soc. 2012, 134:19223-19233.
108. Tevis D.S., Kumar A., Stephens C.E., Boykin D.W., Wilson W.D. Nucleic Acids Res. 2009, 37:5550-5558.
109. Talib J., Beck J.L., Urathamakul T., Nguyen C.D., Aldrich-Wright J.R., Mackay J.P., Ralph S.F. Chem. Commun. 2009, 5546-5548.
110. Scott E.W., Simon M.C., Anastasi J., Singh H. Science 1994, 265:1573-1577.
111. Raja N.S., Nair B.U. Toxicology 2008, 251:61-65.
112. Vijayalakshmi R., Kanthimathi M., Subramanian V., Nair B.U. Biochim. Biophys. Acta 2000, 1475:157-162.
113. Wang P., Leung C.H., Ma D.L., Sun R.W., Yan S.C., Chen Q.S., Che C.M. Angew. Chem. Int. Ed. 2011, 50:2554-2558.
114. Conkright M.D., Montminy M. Trends Cell Biol. 2005, 15:457-459.
115. Sakamoto K.M., Frank D.A. Clin. Cancer Res. 2009, 15:2583-2587.
116. Olivova R., Kasparkova J., Vrana O., Vojtiskova M., Suchankova T., Novakova O., He W., Guo Z., Brabec V. Mol. Pharm. 2011, 8:2368-2378.
117. Zhao Y., He W., Shi P., Zhu J., Qiu L., Lin L., Guo Z. Dalton Trans. 2006, 2617-2619.
118. Wu P., Ma D.L., Leung C.H., Yan S.C., Zhu N., Abagyan R., Che C.M. Chem. Eur. J. 2009, 15:13008-13021.
119. Wang P., Leung C.H., Ma D.L., Yan S.C., Che C.M. Chem. Eur. J. 2010, 16:6900-6911.
120. Zeller K.I., Zhao X., Lee C.W., Chiu K.P., Yao F., Yustein J.T., Ooi H.S., Orlov Y.L., Shahab A., Yong H.C., Fu Y., Weng Z., Kuznetsov V.A., Sung W.K., Ruan Y., Dang C.V., Wei C.L. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:17834-17839.
121. Feng L., Geisselbrecht Y., Blanck S., Wilbuer A., Atilla-Gokcumen G.E., Filippakopoulos P., Kraling K., Celik M.A., Harms K., Maksimoska J., Marmorstein R., Frenking G., Knapp S., Essen L.O., Meggers E. J. Am. Chem. Soc. 2011, 133:5976-5986.
122. Wang J., Kim J., Roh M., Franco O.E., Hayward S.W., Wills M.L., Abdulkadir S.A. Oncogene 2010, 29:2477-2487.
123. Liu J., Sun R.W., Leung C.H., Lok C.N., Che C.M. Chem. Commun. 2012, 48:230-232.
124. Chen L.F., Greene W.C. Nat. Rev. Mol. Cell Biol. 2004, 5:392-401.
125. Pikarsky E., Porat R.M., Stein I., Abramovitch R., Amit S., Kasem S., Gutkovich-Pyest E., Urieli-Shoval S., Galun E., Ben-Neriah Y. Nature 2004, 431:461-466.
126. Viatour P., Merville M.P., Bours V., Chariot A. Trends Biochem. Sci. 2005, 30:43-52.
127. Liu J., Leung C.H., Chow A.L., Sun R.W., Yan S.C., Che C.M. Chem. Commun. 2011, 47:719-721.
128. Hentze H., Latta M., Kunstle G., Dhakshinamoorthy S., Ng P.Y., Porter A.G., Wendel A. Hepatology 2004, 39:1311-1320.
129. Leung C.H., Chan D.S., Kwan M.H., Cheng Z., Wong C.Y., Zhu G.Y., Fong W.F., Ma D.L. ChemMedChem 2011, 6:765-768.
130. Napetschnig J., Wu H. Annu. Rev. Biophys. 2013, 42:443-468.
131. He M.M., Smith A.S., Oslob J.D., Flanagan W.M., Braisted A.C., Whitty A., Cancilla M.T., Wang J., Lugovskoy A.A., Yoburn J.C., Fung A.D., Farrington G., Eldredge J.K., Day E.S., Cruz L.A., Cachero T.G., Miller S.K., Friedman J.E., Choong I.C., Cunningham B.C. Science 2005, 310:1022-1025.
132. Chan D.S., Lee H.M., Yang F., Che C.M., Wong C.C., Abagyan R., Leung C.H., Ma D.L. Angew. Chem. Int. Ed. 2010, 49:2860-2864.
133. Kumar K.S., Kumar P.M., Kumar K.A., Sreenivasulu M., Jafar A.A., Rambabu D., Krishna G.R., Reddy C.M., Kapavarapu R., Shivakumar K., Priya K.K., Parsa K.V., Pal M. Chem. Commun. 2011, 47:5010-5012.
134. Kanemaru Y., Momiki Y., Matsuura S., Horikawa T., Gohda J., Inoue J., Okamoto Y., Fujita M., Otsuka M. Chem. Pharm. Bull. 2011, 59:1555-1558.
135. Satake H., Suzuki K., Aoki T., Otsuka M., Sugiura Y., Yamamoto T., Inoue J. Biochem. Biophys. Res. Commun. 1995, 216:568-573.
136. Tisato F., Marzano C., Porchia M., Pellei M., Santini C. Med. Res. Rev. 2010, 30:708-749.
137. Madani F., Lindberg S., Langel U., Futaki S., Graslund A. J. Biophys. 2011, 2011:414729.
138. Sava G., Bergamo A., Dyson P.J. Dalton Trans. 2011, 40:9069-9075.
139. Gianferrara T., Bratsos I., Alessio E. Dalton Trans. 2009, 7588-7598.
140. Dyson P.J., Sava G. Dalton Trans. 2006, 1929-1933.
141. Fricker S.P. Dalton Trans. 2007, 4903-4917.
142. Meggers E. Angew. Chem. Int. Ed. 2011, 50:2442-2448.
143. Thangudu R.R., Bryant S.H., Panchenko A.R., Madej T. J. Mol. Biol. 2012, 415:443-453.
144. Whitty A., Kumaravel G. Nat. Chem. Biol. 2006, 2:112-118.
145. Thiel P., Kaiser M., Ottmann C. Angew. Chem. Int. Ed. 2012, 51:2012-2018.
146. Leung C.-H., Zhong H.-J., Yang H., Cheng Z., Chan D.S.-H., Ma V.P.-Y., Abagyan R., Wong C.-Y., Ma D.-L. Angew. Chem. Int. Ed. 2012, 51:9010-9014.
147. Gasser G., Ott I., Metzler-Nolte N. J. Med. Chem. 2010, 54:3-25.
148. Fernández A., Crespo A., Tiwari A. Drug Discov. Today 2009, 14:1-5.