Unique DNA binding mode of antitumor trinuclear tridentate platinum(II) compound

Molecular Pharmaceutics

Volumn 8, Issue 6, 2011, Pages 2368-2378

  Olivova, Radana ^a,b   Kasparkova, Jana ^b   Vrana, Oldrich ^b   Vojtiskova, Marie ^b   Suchankova, Tereza ^a,b   Novakova, Olga ^b   He, Weijiang ^c   Guo, Zijian ^c   Brabec, Viktor ^b  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b INSTITUTE OF BIOPHYSICS   (Czech Republic)

^c NANJING UNIVERSITY   (China)

Author keywords

antitumor; DNA binding; DNA protein cross links; interduplex cross links; platinum drug

Indexed keywords

DOUBLE STRANDED DNA; PLATINUM COMPLEX; TRIPLATINUM TRICHLORO N,N,N',N',N'',N'' HEXAKIS(2 PYRIDYLMETHYL) 1,3,5 TRIS(AMINOMETHYL)BENZENE; UNCLASSIFIED DRUG;

ARTICLE; DNA ADDUCT; DNA CROSS LINKING; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG EFFECT; DRUG MECHANISM; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CROSS-LINKING REAGENTS; DNA; HUMANS; MICE; MOLECULAR STRUCTURE; ORGANOPLATINUM COMPOUNDS;

EID: 82955172965     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200298g     Document Type: Article

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