DNA mismatch binding and antiproliferative activity of rhodium metalloinsertors

Journal of the American Chemical Society

Volumn 131, Issue 6, 2009, Pages 2359-2366

  Ernst, Russell J ^a   Song, Hang ^a   Barton, Jacqueline K ^a  

^a California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CELL CULTURE; CELL MEMBRANES; CELL PROLIFERATION; DNA; GENES; LIGANDS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; RHODIUM;

ANCILLARY LIGANDS; ANTIPROLIFERATIVE ACTIVITIES; BASE PAIRS; BINDING AFFINITIES; BIOLOGICAL EFFECTS; CELL LINES; CELLULAR PROLIFERATIONS; COLORECTAL CARCINOMA; DIIMINE COMPLEXES; DNA BINDING AFFINITY; DNA PHOTO-CLEAVAGE; HIGH SPECIFICITY; IN-VIVO; MINOR GROOVES; MISMATCH REPAIR; MODEL SYSTEM; PHOTOCLEAVAGE;

RHODIUM COMPOUNDS;

LIGAND; OLIGONUCLEOTIDE; RHODIUM COMPLEX; (RH(BPY)2(CHRYSI))3+; 5,6-CHRYSENEQUINONE; CHRYSENE DERIVATIVE; DNA; ORGANOMETALLIC COMPOUND; PHENANTHRENE DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; QUINONE DERIVATIVE; RHODIUM;

ARTICLE; BASE MISPAIRING; BINDING AFFINITY; BINDING COMPETITION; CANCER INHIBITION; CARCINOMA CELL; CELL LINE; COLORECTAL CARCINOMA; CONCENTRATION (PARAMETERS); DNA BINDING; DNA CLEAVAGE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MISMATCH REPAIR; TITRIMETRY; CELL GROWTH; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; HCT116 CELL LINE;

BASE PAIR MISMATCH; CELL GROWTH PROCESSES; CHRYSENES; DNA; DNA MISMATCH REPAIR; HCT116 CELLS; HUMANS; MODELS, MOLECULAR; ORGANOMETALLIC COMPOUNDS; PHENANTHRENES; QUATERNARY AMMONIUM COMPOUNDS; QUINONES; RHODIUM;

EID: 67749102052     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8081044     Document Type: Article

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