DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 42, 2006, Pages 15359-15363

  Hart, Jonathan R ^a   Glebov, Oleg ^b   Ernst, Russell J ^a   Kirsch, Ilan R ^b,c   Barton, Jacqueline K ^a  

^a California Institute of Technology   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c AMGEN INC   (United States)

Author keywords

DNA base mismatch; Metallointercalator

Indexed keywords

DNA; INTERCALATING AGENT; RHODIUM; RHODIUM COMPLEX;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; CANCER CELL CULTURE; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA SYNTHESIS INHIBITION; FIBROBLAST; GENE TARGETING; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; INTERCALATION COMPLEX; ISOMER; MISMATCH REPAIR; MOUSE; NONHUMAN; PHOTOACTIVATION; PRIORITY JOURNAL;

ANIMALS; BASE PAIR MISMATCH; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; DNA; DNA MISMATCH REPAIR; HUMANS; INTERCALATING AGENTS; MICE; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; RHODIUM; STEREOISOMERISM;

EID: 33750349226     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607576103     Document Type: Article

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