-
1
-
-
0036675220
-
Metastasis to bone: causes, consequences and therapeutic opportunities
-
Mundy G.R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002, 2:584-593.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
2
-
-
77954861745
-
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer
-
Creighton C.J., Chang J.C., Rosen J.M. Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia 2010, 15:253-260.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 253-260
-
-
Creighton, C.J.1
Chang, J.C.2
Rosen, J.M.3
-
3
-
-
33846489816
-
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2
-
Young D.W., Hassan M.Q., Pratap J., Galindo M., Zaidi S.K., Lee S.H., et al. Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature 2007, 445:442-446.
-
(2007)
Nature
, vol.445
, pp. 442-446
-
-
Young, D.W.1
Hassan, M.Q.2
Pratap, J.3
Galindo, M.4
Zaidi, S.K.5
Lee, S.H.6
-
4
-
-
44349121057
-
Phenotypic transcription factors epigenetically mediate cell growth control
-
Ali S.A., Zaidi S.K., Dacwag C.S., Salma N., Young D.W., Shakoori A.R., et al. Phenotypic transcription factors epigenetically mediate cell growth control. Proc Natl Acad Sci U S A 2008, 105:6632-6637.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6632-6637
-
-
Ali, S.A.1
Zaidi, S.K.2
Dacwag, C.S.3
Salma, N.4
Young, D.W.5
Shakoori, A.R.6
-
5
-
-
59449094492
-
The leukemogenic t(8;21) fusion protein AML1-ETO controls ribosomal RNA genes and associates with nucleaolar organizing regions at mitotic chromosomes
-
Bakshi R., Zaidi S.K., Pande S., Hassan M.Q., Young D.W., Montecino M., et al. The leukemogenic t(8;21) fusion protein AML1-ETO controls ribosomal RNA genes and associates with nucleaolar organizing regions at mitotic chromosomes. J Cell Sci 2008, 21:3981-3990.
-
(2008)
J Cell Sci
, vol.21
, pp. 3981-3990
-
-
Bakshi, R.1
Zaidi, S.K.2
Pande, S.3
Hassan, M.Q.4
Young, D.W.5
Montecino, M.6
-
6
-
-
18344372018
-
The runx genes: gain or loss of function in cancer
-
Blyth K., Cameron E.R., Neil J.C. The runx genes: gain or loss of function in cancer. Nat Rev Cancer 2005, 5:376-387.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 376-387
-
-
Blyth, K.1
Cameron, E.R.2
Neil, J.C.3
-
7
-
-
2942667930
-
Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia
-
Osato M. Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia. Oncogene 2004, 23:4284-4296.
-
(2004)
Oncogene
, vol.23
, pp. 4284-4296
-
-
Osato, M.1
-
8
-
-
77952237515
-
RUNX3 is multifunctional in carcinogenesis of multiple solid tumors
-
Chuang L.S., Ito Y. RUNX3 is multifunctional in carcinogenesis of multiple solid tumors. Oncogene 2010, 29:2605-2615.
-
(2010)
Oncogene
, vol.29
, pp. 2605-2615
-
-
Chuang, L.S.1
Ito, Y.2
-
9
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T., Yagi H., Nomura S., Yamaguchi A., Sasaki K., Deguchi K., et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997, 89:755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
-
10
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F., Thornell A.P., Crompton T., Denzel A., Gilmour K.C., Rosewell I.R., et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997, 89:765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
-
11
-
-
0035902565
-
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
-
Choi J.-Y., Pratap J., Javed A., Zaidi S.K., Xing L., Balint E., et al. Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc Natl Acad Sci U S A 2001, 98:8650-8655.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8650-8655
-
-
Choi, J.-Y.1
Pratap, J.2
Javed, A.3
Zaidi, S.K.4
Xing, L.5
Balint, E.6
-
12
-
-
10344237022
-
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
-
Thomas D.M., Johnson S.A., Sims N.A., Trivett M.K., Slavin J.L., Rubin B.P., et al. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J Cell Biol 2004, 167:925-934.
-
(2004)
J Cell Biol
, vol.167
, pp. 925-934
-
-
Thomas, D.M.1
Johnson, S.A.2
Sims, N.A.3
Trivett, M.K.4
Slavin, J.L.5
Rubin, B.P.6
-
13
-
-
56649109716
-
Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma
-
Nathan S.S., Pereira B.P., Zhou Y.F., Gupta A., Dombrowski C., Soong R., et al. Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma. Mol Biol Rep 2009, 36:153-158.
-
(2009)
Mol Biol Rep
, vol.36
, pp. 153-158
-
-
Nathan, S.S.1
Pereira, B.P.2
Zhou, Y.F.3
Gupta, A.4
Dombrowski, C.5
Soong, R.6
-
14
-
-
3042825286
-
Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases associated osteolytic disease
-
Barnes G.L., Hebert K.E., Kamal M., Javed A., Einhorn T.A., Lian J.B., et al. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases associated osteolytic disease. Cancer Res 2004, 64:4506-4513.
-
(2004)
Cancer Res
, vol.64
, pp. 4506-4513
-
-
Barnes, G.L.1
Hebert, K.E.2
Kamal, M.3
Javed, A.4
Einhorn, T.A.5
Lian, J.B.6
-
15
-
-
13444306168
-
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo
-
Javed A., Barnes G.L., Pratap J., Antkowiak T., Gerstenfeld L.C., van Wijnen A.J., et al. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Sci U S A 2005, 102:1454-1459.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1454-1459
-
-
Javed, A.1
Barnes, G.L.2
Pratap, J.3
Antkowiak, T.4
Gerstenfeld, L.C.5
van Wijnen, A.J.6
-
16
-
-
70149098945
-
Ectopic Runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression
-
Pratap J., Imbalzano K., Underwood J., Cohet N., Gokul K.D., Akech J., et al. Ectopic Runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression. Cancer Res 2009, 69:6807-6814.
-
(2009)
Cancer Res
, vol.69
, pp. 6807-6814
-
-
Pratap, J.1
Imbalzano, K.2
Underwood, J.3
Cohet, N.4
Gokul, K.D.5
Akech, J.6
-
17
-
-
33846034921
-
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone
-
Pratap J., Lian J.B., Javed A., Barnes G.L., van Wijnen A.J., Stein J.L., et al. Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. Cancer Metastasis Rev 2006, 25:589-600.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 589-600
-
-
Pratap, J.1
Lian, J.B.2
Javed, A.3
Barnes, G.L.4
van Wijnen, A.J.5
Stein, J.L.6
-
18
-
-
69249206543
-
The critical role of the bone microenvironment in cancer metastases
-
Casimiro S., Guise T.A., Chirgwin J. The critical role of the bone microenvironment in cancer metastases. Mol Cell Endocrinol 2009, 310:71-81.
-
(2009)
Mol Cell Endocrinol
, vol.310
, pp. 71-81
-
-
Casimiro, S.1
Guise, T.A.2
Chirgwin, J.3
-
19
-
-
38049155882
-
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential
-
Zaidi S.K., Pande S., Pratap J., Gaur T., Grigoriu S., Ali S.A., et al. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential. Proc Natl Acad Sci U S A 2007, 104:19861-19866.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19861-19866
-
-
Zaidi, S.K.1
Pande, S.2
Pratap, J.3
Gaur, T.4
Grigoriu, S.5
Ali, S.A.6
-
20
-
-
34249334327
-
Nuclear microenvironments in biological control and cancer
-
Zaidi S.K., Young D.W., Javed A., Pratap J., Montecino M., van Wijnen A., et al. Nuclear microenvironments in biological control and cancer. Nat Rev Cancer 2007, 7:454-463.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 454-463
-
-
Zaidi, S.K.1
Young, D.W.2
Javed, A.3
Pratap, J.4
Montecino, M.5
van Wijnen, A.6
-
21
-
-
0141705433
-
Cell growth regulatory role of Runx2 during proliferative expansion of pre-osteoblasts
-
Pratap J., Galindo M., Zaidi S.K., Vradii D., Bhat B.M., Robinson J.A., et al. Cell growth regulatory role of Runx2 during proliferative expansion of pre-osteoblasts. Cancer Res 2003, 63:5357-5362.
-
(2003)
Cancer Res
, vol.63
, pp. 5357-5362
-
-
Pratap, J.1
Galindo, M.2
Zaidi, S.K.3
Vradii, D.4
Bhat, B.M.5
Robinson, J.A.6
-
22
-
-
0038460942
-
Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo
-
Lian J.B., Balint E., Javed A., Drissi H., Vitti R., Quinlan E.J., et al. Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo. J Cell Physiol 2003, 196:301-311.
-
(2003)
J Cell Physiol
, vol.196
, pp. 301-311
-
-
Lian, J.B.1
Balint, E.2
Javed, A.3
Drissi, H.4
Vitti, R.5
Quinlan, E.J.6
-
23
-
-
20044364559
-
Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development
-
Smith N., Dong Y., Lian J.B., Pratap J., Kingsley P.D., van Wijnen A.J., et al. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol 2005, 203:133-143.
-
(2005)
J Cell Physiol
, vol.203
, pp. 133-143
-
-
Smith, N.1
Dong, Y.2
Lian, J.B.3
Pratap, J.4
Kingsley, P.D.5
van Wijnen, A.J.6
-
24
-
-
25444443688
-
Modelling glandular epithelial cancers in three-dimensional cultures
-
Debnath J., Brugge J.S. Modelling glandular epithelial cancers in three-dimensional cultures. Nat Rev Cancer 2005, 5:675-688.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 675-688
-
-
Debnath, J.1
Brugge, J.S.2
-
25
-
-
0033119507
-
Tissue structure, nuclear organization, and gene expression in normal and malignant breast
-
Bissell M.J., Weaver V.M., Lelievre S.A., Wang F., Petersen O.W., Schmeichel K.L. Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res 1999, 59:1757s-1763s.
-
(1999)
Cancer Res
, vol.59
-
-
Bissell, M.J.1
Weaver, V.M.2
Lelievre, S.A.3
Wang, F.4
Petersen, O.W.5
Schmeichel, K.L.6
-
26
-
-
16244399183
-
Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein
-
Inman C.K., Li N., Shore P. Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein. Mol Cell Biol 2005, 25:3182-3193.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3182-3193
-
-
Inman, C.K.1
Li, N.2
Shore, P.3
-
27
-
-
68749118305
-
Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer
-
Das K., Leong D.T., Gupta A., Shen L., Putti T., Stein G.S., et al. Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer. Eur J Cancer 2009, 45:2239-2248.
-
(2009)
Eur J Cancer
, vol.45
, pp. 2239-2248
-
-
Das, K.1
Leong, D.T.2
Gupta, A.3
Shen, L.4
Putti, T.5
Stein, G.S.6
-
28
-
-
75949085815
-
Runx2 regulates survivin expression in prostate cancer cells
-
Lim M., Zhong C., Yang S., Bell A.M., Cohen M.B., Roy-Burman P. Runx2 regulates survivin expression in prostate cancer cells. Lab Invest 2010, 90:222-233.
-
(2010)
Lab Invest
, vol.90
, pp. 222-233
-
-
Lim, M.1
Zhong, C.2
Yang, S.3
Bell, A.M.4
Cohen, M.B.5
Roy-Burman, P.6
-
29
-
-
37549036729
-
Survivin, cancer networks and pathway-directed drug discovery
-
Altieri D.C. Survivin, cancer networks and pathway-directed drug discovery. Nat Rev Cancer 2008, 8:61-70.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 61-70
-
-
Altieri, D.C.1
-
30
-
-
76749108468
-
Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment
-
Morrissey C., Brown L.G., Pitts T.E., Vessella R.L., Corey E. Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment. Neoplasia 2010, 12:192-205.
-
(2010)
Neoplasia
, vol.12
, pp. 192-205
-
-
Morrissey, C.1
Brown, L.G.2
Pitts, T.E.3
Vessella, R.L.4
Corey, E.5
-
31
-
-
33646271828
-
Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways
-
Yang S., Lim M., Pham L.K., Kendall S.E., Reddi A.H., Altieri D.C., et al. Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways. Cancer Res 2006, 66:4285-4290.
-
(2006)
Cancer Res
, vol.66
, pp. 4285-4290
-
-
Yang, S.1
Lim, M.2
Pham, L.K.3
Kendall, S.E.4
Reddi, A.H.5
Altieri, D.C.6
-
32
-
-
58549091280
-
BMP7 influences proliferation, migration, and invasion of breast cancer cells
-
Alarmo E.L., Parssinen J., Ketolainen J.M., Savinainen K., Karhu R., Kallioniemi A. BMP7 influences proliferation, migration, and invasion of breast cancer cells. Cancer Lett 2009, 275:35-43.
-
(2009)
Cancer Lett
, vol.275
, pp. 35-43
-
-
Alarmo, E.L.1
Parssinen, J.2
Ketolainen, J.M.3
Savinainen, K.4
Karhu, R.5
Kallioniemi, A.6
-
33
-
-
0035873861
-
Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro
-
Lin D.L., Tarnowski C.P., Zhang J., Dai J., Rohn E., Patel A.H., et al. Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro. Prostate 2001, 47:212-221.
-
(2001)
Prostate
, vol.47
, pp. 212-221
-
-
Lin, D.L.1
Tarnowski, C.P.2
Zhang, J.3
Dai, J.4
Rohn, E.5
Patel, A.H.6
-
34
-
-
43749091299
-
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal
-
Javed A., Bae J.S., Afzal F., Gutierrez S., Pratap J., Zaidi S.K., et al. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J Biol Chem 2008, 283:8412-8422.
-
(2008)
J Biol Chem
, vol.283
, pp. 8412-8422
-
-
Javed, A.1
Bae, J.S.2
Afzal, F.3
Gutierrez, S.4
Pratap, J.5
Zaidi, S.K.6
-
35
-
-
39749187284
-
Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer
-
Bellahcene A., Castronovo V., Ogbureke K.U., Fisher L.W., Fedarko N.S. Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer. Nat Rev Cancer 2008, 8:212-226.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 212-226
-
-
Bellahcene, A.1
Castronovo, V.2
Ogbureke, K.U.3
Fisher, L.W.4
Fedarko, N.S.5
-
36
-
-
0034914814
-
Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2
-
Zelzer E., Glotzer D.J., Hartmann C., Thomas D., Fukai N., Soker S., et al. Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev 2001, 106:97-106.
-
(2001)
Mech Dev
, vol.106
, pp. 97-106
-
-
Zelzer, E.1
Glotzer, D.J.2
Hartmann, C.3
Thomas, D.4
Fukai, N.5
Soker, S.6
-
37
-
-
15144361970
-
CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation
-
Ji C., Casinghino S., Chang D.J., Chen Y., Javed A., Ito Y., et al. CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation. J Cell Biochem 1998, 69:353-363.
-
(1998)
J Cell Biochem
, vol.69
, pp. 353-363
-
-
Ji, C.1
Casinghino, S.2
Chang, D.J.3
Chen, Y.4
Javed, A.5
Ito, Y.6
-
38
-
-
77951709842
-
Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface
-
Nannuru K.C., Futakuchi M., Varney M.L., Vincent T.M., Marcusson E.G., Singh R.K. Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer Res 2010, 70:3494-3504.
-
(2010)
Cancer Res
, vol.70
, pp. 3494-3504
-
-
Nannuru, K.C.1
Futakuchi, M.2
Varney, M.L.3
Vincent, T.M.4
Marcusson, E.G.5
Singh, R.K.6
-
39
-
-
25444473106
-
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
-
Pratap J., Javed A., Languino L.R., van Wijnen A.J., Stein J.L., Stein G.S., et al. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 2005, 25:8581-8591.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8581-8591
-
-
Pratap, J.1
Javed, A.2
Languino, L.R.3
van Wijnen, A.J.4
Stein, J.L.5
Stein, G.S.6
-
40
-
-
0037241624
-
Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation
-
Franceschi R.T., Xiao G., Jiang D., Gopalakrishnan R., Yang S., Reith E. Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation. Connect Tissue Res 2003, 44(Suppl 1):109-116.
-
(2003)
Connect Tissue Res
, vol.44
, Issue.SUPPL. 1
, pp. 109-116
-
-
Franceschi, R.T.1
Xiao, G.2
Jiang, D.3
Gopalakrishnan, R.4
Yang, S.5
Reith, E.6
-
41
-
-
72949119124
-
Integrins in cancer: biological implications and therapeutic opportunities
-
Desgrosellier J.S., Cheresh D.A. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 2010, 10:9-22.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
42
-
-
72849130461
-
Integrins in bone metastasis formation and potential therapeutic implications
-
Clezardin P. Integrins in bone metastasis formation and potential therapeutic implications. Curr Cancer Drug Targets 2009, 9:801-806.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 801-806
-
-
Clezardin, P.1
-
43
-
-
54249097017
-
Runx2 transcriptional activation of Indian hedgehog and a downstream bone metastatic pathway in breast cancer cells
-
Pratap J., Wixted J.J., Gaur T., Zaidi S.K., Dobson J., Gokul K.D., et al. Runx2 transcriptional activation of Indian hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res 2008, 68:7795-7802.
-
(2008)
Cancer Res
, vol.68
, pp. 7795-7802
-
-
Pratap, J.1
Wixted, J.J.2
Gaur, T.3
Zaidi, S.K.4
Dobson, J.5
Gokul, K.D.6
-
44
-
-
76849112495
-
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
-
Akech J., Wixted J.J., Bedard K., van der Deen M., Hussain S., Guise T.A., et al. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene 2010, 29:811-821.
-
(2010)
Oncogene
, vol.29
, pp. 811-821
-
-
Akech, J.1
Wixted, J.J.2
Bedard, K.3
van der Deen, M.4
Hussain, S.5
Guise, T.A.6
-
45
-
-
40649090942
-
Molecular mechanisms and treatment of bone metastasis
-
Clines G.A., Guise T.A. Molecular mechanisms and treatment of bone metastasis. Expert Rev Mol Med 2008, 10:e7.
-
(2008)
Expert Rev Mol Med
, vol.10
-
-
Clines, G.A.1
Guise, T.A.2
-
46
-
-
33747890209
-
The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells
-
Sterling J.A., Oyajobi B.O., Grubbs B., Padalecki S.S., Munoz S.A., Gupta A., et al. The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells. Cancer Res 2006, 66:7548-7553.
-
(2006)
Cancer Res
, vol.66
, pp. 7548-7553
-
-
Sterling, J.A.1
Oyajobi, B.O.2
Grubbs, B.3
Padalecki, S.S.4
Munoz, S.A.5
Gupta, A.6
-
47
-
-
48649094682
-
Histopathological assessment of prostate cancer bone osteoblastic metastases
-
Roudier M.P., Morrissey C., True L.D., Higano C.S., Vessella R.L., Ott S.M. Histopathological assessment of prostate cancer bone osteoblastic metastases. J Urol 2008, 180:1154-1160.
-
(2008)
J Urol
, vol.180
, pp. 1154-1160
-
-
Roudier, M.P.1
Morrissey, C.2
True, L.D.3
Higano, C.S.4
Vessella, R.L.5
Ott, S.M.6
-
48
-
-
0038242432
-
Prostate cancer expression of runt-domain transcription factor Runx2, a key regulator of osteoblast differentiation and function
-
Brubaker K.D., Vessella R.L., Brown L.G., Corey E. Prostate cancer expression of runt-domain transcription factor Runx2, a key regulator of osteoblast differentiation and function. Prostate 2003, 56:13-22.
-
(2003)
Prostate
, vol.56
, pp. 13-22
-
-
Brubaker, K.D.1
Vessella, R.L.2
Brown, L.G.3
Corey, E.4
-
49
-
-
77749321132
-
The cancer-related Runx2 protein enhances cell growth and responses to andogen and TGFβ in prostate cancer cells
-
van der Deen M., Akech J., Wang T., FitzGerald T.J., Altieri D.C., Languino L.R., et al. The cancer-related Runx2 protein enhances cell growth and responses to andogen and TGFβ in prostate cancer cells. J Cell Biochem 2010, 109:828-837.
-
(2010)
J Cell Biochem
, vol.109
, pp. 828-837
-
-
van der Deen, M.1
Akech, J.2
Wang, T.3
FitzGerald, T.J.4
Altieri, D.C.5
Languino, L.R.6
-
51
-
-
34347377165
-
When prostate cancer meets bone: control by wnts
-
Emami K.H., Corey E. When prostate cancer meets bone: control by wnts. Cancer Lett 2007, 253:170-179.
-
(2007)
Cancer Lett
, vol.253
, pp. 170-179
-
-
Emami, K.H.1
Corey, E.2
-
52
-
-
33846150682
-
The role of Wnts in bone metastases
-
Hall C.L., Keller E.T. The role of Wnts in bone metastases. Cancer Metastasis Rev 2006, 25:551-558.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 551-558
-
-
Hall, C.L.1
Keller, E.T.2
-
53
-
-
75749103348
-
Src signaling in cancer invasion
-
Guarino M. Src signaling in cancer invasion. J Cell Physiol 2010, 223:14-26.
-
(2010)
J Cell Physiol
, vol.223
, pp. 14-26
-
-
Guarino, M.1
-
54
-
-
1842457741
-
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
-
Zaidi S.K., Sullivan A.J., Medina R., Ito Y., van Wijnen A.J., Stein J.L., et al. Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J 2004, 23:790-799.
-
(2004)
EMBO J
, vol.23
, pp. 790-799
-
-
Zaidi, S.K.1
Sullivan, A.J.2
Medina, R.3
Ito, Y.4
van Wijnen, A.J.5
Stein, J.L.6
-
55
-
-
77952203697
-
SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis
-
Rabbani S.A., Valentino M.L., Arakelian A., Ali S., Boschelli F. SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis. Mol Cancer Ther 2010, 9:1147-1157.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1147-1157
-
-
Rabbani, S.A.1
Valentino, M.L.2
Arakelian, A.3
Ali, S.4
Boschelli, F.5
-
56
-
-
77956072809
-
Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors
-
Electronic publication ahead of print
-
Araujo J., Logothetis C. Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors. Cancer Treat Rev 2010, Electronic publication ahead of print.
-
(2010)
Cancer Treat Rev
-
-
Araujo, J.1
Logothetis, C.2
-
57
-
-
77950616066
-
SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer
-
Saad F., Lipton A. SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer. Cancer Treat Rev 2010, 36:177-184.
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 177-184
-
-
Saad, F.1
Lipton, A.2
-
58
-
-
0037439923
-
Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells
-
Pouliot F., Blais A., Labrie C. Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells. Cancer Res 2003, 63:277-281.
-
(2003)
Cancer Res
, vol.63
, pp. 277-281
-
-
Pouliot, F.1
Blais, A.2
Labrie, C.3
-
59
-
-
2942574380
-
Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins
-
Miyazono K., Maeda S., Imamura T. Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins. Oncogene 2004, 23:4232-4237.
-
(2004)
Oncogene
, vol.23
, pp. 4232-4237
-
-
Miyazono, K.1
Maeda, S.2
Imamura, T.3
-
60
-
-
65249178875
-
The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells
-
Ford A.M., Palmi C., Bueno C., Hong D., Cardus P., Knight D., et al. The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells. J Clin Invest 2009, 119:826-836.
-
(2009)
J Clin Invest
, vol.119
, pp. 826-836
-
-
Ford, A.M.1
Palmi, C.2
Bueno, C.3
Hong, D.4
Cardus, P.5
Knight, D.6
-
61
-
-
0037310863
-
RUNX transcription factors as key targets of TGF-beta superfamily signaling
-
Ito Y., Miyazono K. RUNX transcription factors as key targets of TGF-beta superfamily signaling. Curr Opin Genet Dev 2003, 13:43-47.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 43-47
-
-
Ito, Y.1
Miyazono, K.2
-
62
-
-
0037126380
-
Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein
-
Lee K.S., Hong S.H., Bae S.C. Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein. Oncogene 2002, 21:7156-7163.
-
(2002)
Oncogene
, vol.21
, pp. 7156-7163
-
-
Lee, K.S.1
Hong, S.H.2
Bae, S.C.3
-
63
-
-
25844509347
-
Canonical WNT signaling promotes osteogenesis by directly stimulating RUNX2 gene expression
-
Gaur T., Lengner C.J., Hovhannisyan H., Bhat R.A., Bodine P.V.N., Komm B.S., et al. Canonical WNT signaling promotes osteogenesis by directly stimulating RUNX2 gene expression. J Biol Chem 2005, 280:33132-33140.
-
(2005)
J Biol Chem
, vol.280
, pp. 33132-33140
-
-
Gaur, T.1
Lengner, C.J.2
Hovhannisyan, H.3
Bhat, R.A.4
Bodine, P.V.N.5
Komm, B.S.6
-
64
-
-
33645243606
-
Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts
-
Kahler R.A., Galindo M., Lian J., Stein G.S., van Wijnen A.J., Westendorf J.J. Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts. J Cell Biochem 2006, 97:969-983.
-
(2006)
J Cell Biochem
, vol.97
, pp. 969-983
-
-
Kahler, R.A.1
Galindo, M.2
Lian, J.3
Stein, G.S.4
van Wijnen, A.J.5
Westendorf, J.J.6
-
65
-
-
38549095978
-
Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone
-
Li Z.G., Yang J., Vazquez E.S., Rose D., Vakar-Lopez F., Mathew P., et al. Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone. Oncogene 2008, 27:596-603.
-
(2008)
Oncogene
, vol.27
, pp. 596-603
-
-
Li, Z.G.1
Yang, J.2
Vazquez, E.S.3
Rose, D.4
Vakar-Lopez, F.5
Mathew, P.6
-
66
-
-
0035878944
-
Prostate cancer cells induce osteoblast differentiation through a Cbfa1-dependent pathway
-
Yang J., Fizazi K., Peleg S., Sikes C.R., Raymond A.K., Jamal N., et al. Prostate cancer cells induce osteoblast differentiation through a Cbfa1-dependent pathway. Cancer Res 2001, 61:5652-5659.
-
(2001)
Cancer Res
, vol.61
, pp. 5652-5659
-
-
Yang, J.1
Fizazi, K.2
Peleg, S.3
Sikes, C.R.4
Raymond, A.K.5
Jamal, N.6
-
67
-
-
48649090754
-
Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms
-
Dai J., Hall C.L., Escara-Wilke J., Mizokami A., Keller J.M., Keller E.T. Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. Cancer Res 2008, 68:5785-5794.
-
(2008)
Cancer Res
, vol.68
, pp. 5785-5794
-
-
Dai, J.1
Hall, C.L.2
Escara-Wilke, J.3
Mizokami, A.4
Keller, J.M.5
Keller, E.T.6
-
68
-
-
47249149740
-
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases
-
Bu G., Lu W., Liu C.C., Selander K., Yoneda T., Hall C., et al. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. Int J Cancer 2008, 123:1034-1042.
-
(2008)
Int J Cancer
, vol.123
, pp. 1034-1042
-
-
Bu, G.1
Lu, W.2
Liu, C.C.3
Selander, K.4
Yoneda, T.5
Hall, C.6
-
69
-
-
67749095787
-
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA
-
Baniwal S.K., Khalid O., Sir D., Buchanan G., Coetzee G.A., Frenkel B. Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA. Mol Endocrinol 2009, 23:1203-1214.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1203-1214
-
-
Baniwal, S.K.1
Khalid, O.2
Sir, D.3
Buchanan, G.4
Coetzee, G.A.5
Frenkel, B.6
-
70
-
-
34250877906
-
Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells
-
Liu X.H., Kirschenbaum A., Yao S., Liu G., Aaronson S.A., Levine A.C. Androgen-induced Wnt signaling in preosteoblasts promotes the growth of MDA-PCa-2b human prostate cancer cells. Cancer Res 2007, 67:5747-5753.
-
(2007)
Cancer Res
, vol.67
, pp. 5747-5753
-
-
Liu, X.H.1
Kirschenbaum, A.2
Yao, S.3
Liu, G.4
Aaronson, S.A.5
Levine, A.C.6
-
71
-
-
30044434221
-
RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region
-
Fowler M., Borazanci E., McGhee L., Pylant S.W., Williams B.J., Glass J., et al. RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region. J Cell Biochem 2006, 97:1-17.
-
(2006)
J Cell Biochem
, vol.97
, pp. 1-17
-
-
Fowler, M.1
Borazanci, E.2
McGhee, L.3
Pylant, S.W.4
Williams, B.J.5
Glass, J.6
-
72
-
-
57349101476
-
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer
-
Khalid O., Baniwal S.K., Purcell D.J., Leclerc N., Gabet Y., Stallcup M.R., et al. Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer. Endocrinology 2008, 149:5984-5995.
-
(2008)
Endocrinology
, vol.149
, pp. 5984-5995
-
-
Khalid, O.1
Baniwal, S.K.2
Purcell, D.J.3
Leclerc, N.4
Gabet, Y.5
Stallcup, M.R.6
-
73
-
-
57449117535
-
Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis
-
Hassan M.Q., Saini S., Gordon J.A., van Wijnen A.J., Montecino M., Stein J.L., et al. Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis. Cells Tissues Organs 2009, 189:122-125.
-
(2009)
Cells Tissues Organs
, vol.189
, pp. 122-125
-
-
Hassan, M.Q.1
Saini, S.2
Gordon, J.A.3
van Wijnen, A.J.4
Montecino, M.5
Stein, J.L.6
-
74
-
-
33846027131
-
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by Dlx3 and a homeodomain transcriptional network
-
Hassan M.Q., Tare R.S., Lee S., Mandeville M., Morasso M.I., Javed A., et al. BMP2 commitment to the osteogenic lineage involves activation of Runx2 by Dlx3 and a homeodomain transcriptional network. J Biol Chem 2006, 281:40515-40526.
-
(2006)
J Biol Chem
, vol.281
, pp. 40515-40526
-
-
Hassan, M.Q.1
Tare, R.S.2
Lee, S.3
Mandeville, M.4
Morasso, M.I.5
Javed, A.6
-
75
-
-
34247608645
-
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes
-
Hassan M.Q., Tare R., Lee S.H., Mandeville M., Weiner B., Montecino M., et al. HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes. Mol Cell Biol 2007, 27:3337-3352.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3337-3352
-
-
Hassan, M.Q.1
Tare, R.2
Lee, S.H.3
Mandeville, M.4
Weiner, B.5
Montecino, M.6
-
76
-
-
77954353828
-
Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors
-
Electronic publication ahead of print
-
Gordon J.A., Hassan M.Q., Saini S., Montecino M., van Wijnen A.J., Stein G.S., et al. Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors. Mol Cell Biol 2010, Electronic publication ahead of print.
-
(2010)
Mol Cell Biol
-
-
Gordon, J.A.1
Hassan, M.Q.2
Saini, S.3
Montecino, M.4
van Wijnen, A.J.5
Stein, G.S.6
-
77
-
-
0037843323
-
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells
-
Barnes G.L., Javed A., Waller S.M., Kamal M.H., Hebert K.E., Hassan M.Q., et al. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res 2003, 63:2631-2637.
-
(2003)
Cancer Res
, vol.63
, pp. 2631-2637
-
-
Barnes, G.L.1
Javed, A.2
Waller, S.M.3
Kamal, M.H.4
Hebert, K.E.5
Hassan, M.Q.6
-
78
-
-
58149085982
-
Msx and dlx homeogene expression in epithelial odontogenic tumors
-
Ruhin-Poncet B., Ghoul-Mazgar S., Hotton D., Capron F., Jaafoura M.H., Goubin G., et al. Msx and dlx homeogene expression in epithelial odontogenic tumors. J Histochem Cytochem 2009, 57:69-78.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 69-78
-
-
Ruhin-Poncet, B.1
Ghoul-Mazgar, S.2
Hotton, D.3
Capron, F.4
Jaafoura, M.H.5
Goubin, G.6
-
79
-
-
59049089015
-
Constitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemia
-
Wang H., Lindsey S., Konieczna I., Bei L., Horvath E., Huang W., et al. Constitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemia. J Biol Chem 2009, 284:2549-2567.
-
(2009)
J Biol Chem
, vol.284
, pp. 2549-2567
-
-
Wang, H.1
Lindsey, S.2
Konieczna, I.3
Bei, L.4
Horvath, E.5
Huang, W.6
-
80
-
-
74749087064
-
The Mullerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions
-
Ko S.Y., Lengyel E., Naora H. The Mullerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol Cell Endocrinol 2010, 317:112-119.
-
(2010)
Mol Cell Endocrinol
, vol.317
, pp. 112-119
-
-
Ko, S.Y.1
Lengyel, E.2
Naora, H.3
-
81
-
-
40749094918
-
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
-
Han H.J., Russo J., Kohwi Y., Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008, 452:187-193.
-
(2008)
Nature
, vol.452
, pp. 187-193
-
-
Han, H.J.1
Russo, J.2
Kohwi, Y.3
Kohwi-Shigematsu, T.4
-
82
-
-
34948880682
-
Histone deacetylases in control of skeletogenesis
-
Westendorf J.J. Histone deacetylases in control of skeletogenesis. J Cell Biochem 2007, 102:332-340.
-
(2007)
J Cell Biochem
, vol.102
, pp. 332-340
-
-
Westendorf, J.J.1
-
83
-
-
28144448363
-
Histone deacetylase inhibitors promote osteoblast maturation
-
Schroeder T.M., Westendorf J.J. Histone deacetylase inhibitors promote osteoblast maturation. J Bone Miner Res 2005, 20:2254-2263.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 2254-2263
-
-
Schroeder, T.M.1
Westendorf, J.J.2
-
84
-
-
70350182197
-
Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL
-
Kim H.N., Ha H., Lee J.H., Jung K., Yang D., Woo K.M., et al. Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. Eur J Pharmacol 2009, 623:22-29.
-
(2009)
Eur J Pharmacol
, vol.623
, pp. 22-29
-
-
Kim, H.N.1
Ha, H.2
Lee, J.H.3
Jung, K.4
Yang, D.5
Woo, K.M.6
-
85
-
-
77951925741
-
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
-
Grabiec A.M., Krausz S., de Jager W., Burakowski T., Groot D., Sanders M.E., et al. Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. J Immunol 2010, 184:2718-2728.
-
(2010)
J Immunol
, vol.184
, pp. 2718-2728
-
-
Grabiec, A.M.1
Krausz, S.2
de Jager, W.3
Burakowski, T.4
Groot, D.5
Sanders, M.E.6
-
86
-
-
70349100446
-
Histone deacetylase inhibitors: current status and overview of recent clinical trials
-
Ma X., Ezzeldin H.H., Diasio R.B. Histone deacetylase inhibitors: current status and overview of recent clinical trials. Drugs 2009, 69:1911-1934.
-
(2009)
Drugs
, vol.69
, pp. 1911-1934
-
-
Ma, X.1
Ezzeldin, H.H.2
Diasio, R.B.3
-
87
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce C.M. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 2009, 10:704-714.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
88
-
-
77950665077
-
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
-
Ma L., Reinhardt F., Pan E., Soutschek J., Bhat B., Marcusson E.G., et al. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 2010, 28:341-347.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 341-347
-
-
Ma, L.1
Reinhardt, F.2
Pan, E.3
Soutschek, J.4
Bhat, B.5
Marcusson, E.G.6
-
89
-
-
74149083873
-
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
-
Takeshita F., Patrawala L., Osaki M., Takahashi R.U., Yamamoto Y., Kosaka N., et al. Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 2010, 18:181-187.
-
(2010)
Mol Ther
, vol.18
, pp. 181-187
-
-
Takeshita, F.1
Patrawala, L.2
Osaki, M.3
Takahashi, R.U.4
Yamamoto, Y.5
Kosaka, N.6
-
90
-
-
66449095667
-
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
-
Valastyan S., Reinhardt F., Benaich N., Calogrias D., Szasz A.M., Wang Z.C., et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009, 137:1032-1046.
-
(2009)
Cell
, vol.137
, pp. 1032-1046
-
-
Valastyan, S.1
Reinhardt, F.2
Benaich, N.3
Calogrias, D.4
Szasz, A.M.5
Wang, Z.C.6
-
91
-
-
85011936092
-
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis
-
Korpal M., Kang Y. The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biol 2008, 5:115-119.
-
(2008)
RNA Biol
, vol.5
, pp. 115-119
-
-
Korpal, M.1
Kang, Y.2
-
92
-
-
77649276051
-
Myc-modulated miR-9 makes more metastases
-
Khew-Goodall Y., Goodall G.J. Myc-modulated miR-9 makes more metastases. Nat Cell Biol 2010, 12:209-211.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 209-211
-
-
Khew-Goodall, Y.1
Goodall, G.J.2
-
93
-
-
70350521699
-
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network
-
Zaidi S.K., Dowdy C.R., van Wijnen A.J., Lian J.B., Raza A., Stein J.L., et al. Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. Cancer Res 2009, 69:8249-8255.
-
(2009)
Cancer Res
, vol.69
, pp. 8249-8255
-
-
Zaidi, S.K.1
Dowdy, C.R.2
van Wijnen, A.J.3
Lian, J.B.4
Raza, A.5
Stein, J.L.6
-
94
-
-
52949114558
-
A microRNA signature for a BMP2-induced osteoblast lineage commitment program
-
Li Z., Hassan M.Q., Volinia S., van Wijnen A.J., Stein J.L., Croce C.M., et al. A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A 2008, 105:13906-13911.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13906-13911
-
-
Li, Z.1
Hassan, M.Q.2
Volinia, S.3
van Wijnen, A.J.4
Stein, J.L.5
Croce, C.M.6
-
95
-
-
77149136767
-
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
-
Huang J., Zhao L., Xing L., Chen D. MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 2010, 28:357-364.
-
(2010)
Stem Cells
, vol.28
, pp. 357-364
-
-
Huang, J.1
Zhao, L.2
Xing, L.3
Chen, D.4
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