Exosomes with membrane-associated TGF-β1 from gene-modified dendritic cells inhibit murine EAE independently of MHC restriction

European Journal of Immunology

Volumn 43, Issue 9, 2013, Pages 2461-2472

  Yu, Lei ^a   Yang, Fei ^a   Jiang, Lingling ^a   Chen, Yinghu ^a   Wang, Keyi ^a   Xu, Feng ^b   Wei, Yinxiang ^a   Cao, Xuetao ^a   Wang, Jianli ^a   Cai, Zhijian ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Autoimmune diseases; Exosomes; TGF 1; Th17; Treg cells

Indexed keywords

CD4 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; MEMBRANE ASSOCIATED TRANSFORMING GROWTH FACTOR BETA1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA2; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENDRITIC CELL; DNA MODIFICATION; DOWN REGULATION; DRUG DELIVERY SYSTEM; ENZYME INACTIVATION; EX VIVO STUDY; EXOSOME; FEMALE; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL;

AUTOIMMUNE DISEASES; EXOSOMES; TGF-Β1; TH17; TREG CELLS;

ADOPTIVE TRANSFER; ANIMALS; AUTOIMMUNITY; CELL PROLIFERATION; CELLS, CULTURED; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME ACTIVATION; EXOSOMES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GREEN FLUORESCENT PROTEINS; IMMUNOSUPPRESSION; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-6; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84883502274     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243295     Document Type: Article

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