Dendritic cell survival and maturation are regulated by different signaling pathways

Journal of Experimental Medicine

Volumn 188, Issue 11, 1998, Pages 2175-2180

  Rescigno, Maria ^a   Martino, Manuela ^a   Sutherland, Claire L ^b   Gold, Michael R ^b   Ricciardi Castagnoli, Paola ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Dendritic cells; Maturation; Mitogen activated protein kinases; Nuclear factor B; Survival

Indexed keywords

GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; ENZYME MECHANISM; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; DENDRITIC CELLS; LIPOPOLYSACCHARIDES; MICE; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 0031775746     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.11.2175     Document Type: Article

References (36)

1. Banchereau, J., and R.M. Steinman. 1998. Dendritic cells and the control of immunity. Nature. 392:245-251.
2. Winzler, C., P. Rovere, M. Rescigno, F. Granucci, G. Penna, L. Adorini, V.S. Zimmermann, J. Davoust, and P. Ricciardi-Castagnoli. 1997. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 185:317-328.
3. De Smedt, T., B. Pajak, E. Muraille, L. Lespagnard, E. Heinen, P. De Baetselier, J. Urbain, O. Leo, and M. Moser. 1996. Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo. J. Exp. Med. 184:1413-1424.
4. Cella, M., A. Hengering, V. Pinet, J. Pieters, and A. Lanzavecchia. 1997. Inflammatory stimuli induces accumulation of MHC class II complexes on dendritic cells. Nature. 388: 782-787.
5. May, M.J., and S. Ghosh. 1998. Signal transduction through NF-kappa B. Immunol. Today. 19:80-88.
6. Baldwin, A.S. 1995. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
7. Beg, A.A., and D. Baltimore. 1996. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 274: 782-784.
8. Wang, C.-Y., M.W. Mayo, and A.S.J. Baldwin. 1996. TNF and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science. 274:784-787.
9. Van Antwerp, D.J., S.J. Martin, T. Kafri, D.R. Green, and I.M. Vermat. 1996. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 274:787-789.
10. Granelli-Piperno, A., M. Pope, K. Inaba, and R.M. Steinman. 1995. Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia. Proc. Natl. Acad. Sci. USA. 92:10944-10948.
11. Cobb, M.H., T.G. Boulton, and D.J. Robbins. 1991. Extra-cellular signal-regulated kinases: ERKs in progress. Cell Regul. 2:965-978.
12. Welham, M.J., V. Duronio, J.S. Sanghera, S.L. Pelech, and W. Schrader. 1992. Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. J. Biol. Chem. 267:1683-1693.
13. Raingeaud, J., S. Gupta, J.S. Rogers, M. Dickens, J. Han, R.J. Ulevitch, and R.J. Davis. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270:7420-7426.
14. Xia, Z., M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1326-1331.
15. Weinstein, S.L., J.S. Sangher, K. Lemke, A.L. DeFranco, and S.L. Pelech. 1992. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J. Biol. Chem. 267:14955-14962.
16. Hambleton, J., L.L. Lem, and A.L. DeFranco. 1996. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA. 93: 2774-2778.
17. Han, J., J.D. Lee, L. Bibbs, and R.J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 265:808-811.
18. Pierre, P., S.J. Turley, E. Gatti, M. Hull, J. Meltzer, A. Mirza, K. Inaba, R.M. Steinman, and I. Mellman. 1997. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature. 388:787-792.
19. Rescigno, M., S. Citterio, C. Théry, M. Rittig, D. Medaglini, G. Pozzi, S. Amigorena, and P. Ricciardi-Castagnoli. 1998. Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. Proc. Natl. Acad. Sci. USA. 95:5229-5234.
20. Saxton, T.M., I. van Oostveen, D. Bowtell, R. Aebersold, and M.R. Gold. 1994. B cell antigen receptor cross-linking induces phosphorylation of the Ras activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein. J. Immunol. 153:623-636.
21. Sutherland, C.L., A.W. Heath, S.L. Pelech, P.R. Young, and M.R. Gold. 1996. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J. Immunol. 157:3381-3390.
22. Cobb, M.H., and E.J. Goldsmith. 1995. How MAP kinases are regulated. J. Biol. Chem. 270:14843-14846.
23. Cano, E., and L.C. Mahadevan. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem. 20:117-122.
24. Cuenda, A, J. Rouse, Y.N. Doza, R. Meier, P. Cohen, T.F. Gallagher, P.R. Young, and J.C. Lee. 1995. SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364:229-233.
25. Dudley, D.T., L. Pang, S.J. Decker, A.J. Bridges, and A.R. Saltiel. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA. 92:7686-7689.
26. Koch, F., C. Heufler, E. Kämpgen, D. Schneeweiss, G. Böck, and G. Schuler. 1990. Tumor necrosis factor α maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturation. J. Exp. Med. 171:159-171.
27. Baeuerle, P.A. 1998. Pro-inflammatory signaling: last pieces in the NF-κB puzzle? Curr. Biol. 8:R19-R22.
28. Grilli, M., J.S. Chiu, and M.J. Lenardo. 1993. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1-62.
29. Baeuerle, P.A., and T. Henkel. 1994. Functional and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
30. Maniatis, T. 1997. Catalysis by a multiprotein IκB kinase complex. Science. 278:818-819.
31. Ruckdeschel, K., S. Harb, A. Roggenkamp, M. Hornef, R. Zumbhil, S. Kohler, J. Heesemann, and B. Rouot. 1998. Yersinia enterocolitica impairs activation of transcription factor NF-κB: involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor α production. J. Exp. Med. 187:1069-1079.
32. Kim, H., H.S. Lee, K.T. Chang, T.H. Ko, K.J. Baek, and N.S. Kwon. 1995. Chloromethyl ketones block induction of nitric oxide synthase in murine macrophages by preventing activation of nuclear factor-κB. J. Immunol. 154:4741-4748.
33. Wu, M., H. Lee, R.E. Bellas, S.L. Schauer, M. Arsura, D. Katz, M.J. FitzGerald, T.L. Rothstein, D.H. Sherr, and G.E. Sonenshein. 1996. Inhibition of NF-κB/Rel induces apoptosis of murine B cells. EMBO (Eur. Mol. Biol. Organ.) J. 15: 4682-4690.
34. Weih, F., D. Carrasco, S.K. Durham, D.S. Barton, C.A. Rizzo, R.P. Ryseck, S.A. Lira, and R. Bravo. 1995. Multi-organ inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NK-κB/Rel family. Cell. 80:331-340.
35. Burkly, L., C. Hession, L. Ogata, C. Reilly, L.A. Marconi, D. Olson, R. Tizard, R. Cate, and D. Lo. 1995. Expression of relB is required for the development of thymic medulla and dendritic cells. Nature. 373:531-536.
36. Grumont, R.J., I.J. Rourke, L.O. O'Reilly, A. Strasser, K. Miyake, W. Sha, and S. Gerondakis. 1998. B lymphocytes differentially use the Rel and nuclear factor KB1 (NF-κB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J. Exp. Med. 187:663-674.