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Volumn 40, Issue 12, 2010, Pages 3321-3324

Treg and T-effector cells in autoimmune CNS inflammation: A delicate balance, easily disturbed

Author keywords

Autoimmune disease; EAE; LFA 1; Multiple sclerosis; Treg

Indexed keywords

LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; TRANSCRIPTION FACTOR FOXP3;

EID: 78649541561     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041100     Document Type: Article
Times cited : (13)

References (22)
  • 1
    • 37849027594 scopus 로고    scopus 로고
    • Foxp3+regulatory T cells in the control of experimental CNS autoimmune disease
    • O'Connor, R. A. and Anderton, S. M., Foxp3+regulatory T cells in the control of experimental CNS autoimmune disease. J. Neuroimmunol. 2008. 193: 1-11.
    • (2008) J. Neuroimmunol. , vol.193 , pp. 1-11
    • O'Connor, R.A.1    Anderton, S.M.2
  • 2
    • 43249128068 scopus 로고    scopus 로고
    • Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system
    • Anderton, S. M. and Liblau, R. S., Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system. Curr. Opin. Neurol. 2008. 21: 248-254.
    • (2008) Curr. Opin. Neurol. , vol.21 , pp. 248-254
    • Anderton, S.M.1    Liblau, R.S.2
  • 3
    • 34147128572 scopus 로고    scopus 로고
    • Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
    • Korn, T., Reddy, J., Gao, W., Bettelli, E., Awasthi, A., Petersen, T. R., Backstrom, B. T. et al., Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat. Med. 2007. 13: 423-431.
    • (2007) Nat. Med. , vol.13 , pp. 423-431
    • Korn, T.1    Reddy, J.2    Gao, W.3    Bettelli, E.4    Awasthi, A.5    Petersen, T.R.6    Backstrom, B.T.7
  • 4
    • 78649556741 scopus 로고    scopus 로고
    • Reduced Treg frequency in LFA-1 deficient mice allows enhanced T effector differentiation and pathology in EAE
    • Gültner, S., Kuhlmann, T., Hesse, A., Weber, J. P., Riemer, C., Baier, M., and Hutloff, A., Reduced Treg frequency in LFA-1 deficient mice allows enhanced T effector differentiation and pathology in EAE. Eur. J. Immunol. 2010. 40: 3403-3412.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3403-3412
    • Gültner, S.1    Kuhlmann, T.2    Hesse, A.3    Weber, J.P.4    Riemer, C.5    Baier, M.6    Hutloff, A.7
  • 5
    • 0242708766 scopus 로고    scopus 로고
    • Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1
    • Perez, O. D., Mitchell, D., Jager, G. C., South, S., Murriel, C., McBride, J., Herzenberg, L. A. et al. Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1. Nat. Immunol. 2003. 4: 1083-1092.
    • (2003) Nat. Immunol. , vol.4 , pp. 1083-1092
    • Perez, O.D.1    Mitchell, D.2    Jager, G.C.3    South, S.4    Murriel, C.5    McBride, J.6    Herzenberg, L.A.7
  • 6
    • 0242708774 scopus 로고    scopus 로고
    • LFA-1: more than just T cell Velcro
    • Shimizu, Y., LFA-1: more than just T cell Velcro. Nat. Immunol. 2003. 4: 1052-1054.
    • (2003) Nat. Immunol. , vol.4 , pp. 1052-1054
    • Shimizu, Y.1
  • 8
    • 0036914616 scopus 로고    scopus 로고
    • Encephalitogenic T cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvessels in vivo
    • Laschinger, M., Vajkoczy, P. and Engelhardt, B., Encephalitogenic T cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvessels in vivo. Eur. J. Immunol. 2002. 32: 3598-3606.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3598-3606
    • Laschinger, M.1    Vajkoczy, P.2    Engelhardt, B.3
  • 9
    • 23844478869 scopus 로고    scopus 로고
    • Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+regulatory cells within the central nervous system
    • McGeachy, M. J., Stephens, L. A. and Anderton, S. M., Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+regulatory cells within the central nervous system. J. Immunol. 2005. 175: 3025-3032.
    • (2005) J. Immunol. , vol.175 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 10
    • 34548734314 scopus 로고    scopus 로고
    • The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+regulatory T cells
    • O'Connor, R. A., Malpass, K. H. and Anderton, S. M., The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+regulatory T cells. J. Immunol. 2007. 179: 958-966.
    • (2007) J. Immunol. , vol.179 , pp. 958-966
    • O'Connor, R.A.1    Malpass, K.H.2    Anderton, S.M.3
  • 12
    • 48249103057 scopus 로고    scopus 로고
    • Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
    • Onishi, Y., Fehervari, Z., Yamaguchi, T. and Sakaguchi, S., Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc. Natl. Acad. Sci. USA 2008. 105: 10113-10118.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 10113-10118
    • Onishi, Y.1    Fehervari, Z.2    Yamaguchi, T.3    Sakaguchi, S.4
  • 13
    • 29144533904 scopus 로고    scopus 로고
    • CD18 is required for optimal development and function of CD4+CD25+T regulatory cells
    • Marski, M., Kandula, S., Turner, J. R. and Abraham, C., CD18 is required for optimal development and function of CD4+CD25+T regulatory cells. J. Immunol. 2005. 175: 7889-7897.
    • (2005) J. Immunol. , vol.175 , pp. 7889-7897
    • Marski, M.1    Kandula, S.2    Turner, J.R.3    Abraham, C.4
  • 14
    • 77950342518 scopus 로고    scopus 로고
    • beta2-integrins in demyelinating disease: not adhering to the paradigm
    • Hu, X., Wohler, J. E., Dugger, K. J. and Barnum, S. R., beta2-integrins in demyelinating disease: not adhering to the paradigm. J. Leukoc. Biol. 2010. 87: 397-403.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 397-403
    • Hu, X.1    Wohler, J.E.2    Dugger, K.J.3    Barnum, S.R.4
  • 15
    • 58149234188 scopus 로고    scopus 로고
    • Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis
    • Dugger, K. J., Zinn, K. R., Weaver, C., Bullard, D. C. and Barnum, S. R., Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2009. 206: 22-27.
    • (2009) J. Neuroimmunol. , vol.206 , pp. 22-27
    • Dugger, K.J.1    Zinn, K.R.2    Weaver, C.3    Bullard, D.C.4    Barnum, S.R.5
  • 16
    • 67349179096 scopus 로고    scopus 로고
    • LFA-1 is critical for regulatory T cell homeostasis and function
    • Wohler, J., Bullard, D., Schoeb, T. and Barnum, S., LFA-1 is critical for regulatory T cell homeostasis and function. Mol. Immunol. 2009. 46: 2424-2428.
    • (2009) Mol. Immunol. , vol.46 , pp. 2424-2428
    • Wohler, J.1    Bullard, D.2    Schoeb, T.3    Barnum, S.4
  • 17
    • 0344780200 scopus 로고    scopus 로고
    • Gene transfer into CD4+T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses
    • Flugel, A., Willem, M., Berkowicz, T. and Wekerle, H., Gene transfer into CD4+T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses. Nat. Med. 1999. 5: 843-847.
    • (1999) Nat. Med. , vol.5 , pp. 843-847
    • Flugel, A.1    Willem, M.2    Berkowicz, T.3    Wekerle, H.4
  • 18
  • 19
    • 3242740010 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+and CD8+T cells: analysis using depleting antibodies
    • Montero, E., Nussbaum, G., Kaye, J. F., Perez, R., Lage, A., Ben-Nun, A. and Cohen, I. R., Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+and CD8+T cells: analysis using depleting antibodies. J. Autoimmun. 2004. 23: 1-7.
    • (2004) J. Autoimmun. , vol.23 , pp. 1-7
    • Montero, E.1    Nussbaum, G.2    Kaye, J.F.3    Perez, R.4    Lage, A.5    Ben-Nun, A.6    Cohen, I.R.7
  • 20
    • 28444444122 scopus 로고    scopus 로고
    • CD4+CD25+regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity
    • Stephens, L. A., Gray, D. and Anderton, S. M., CD4+CD25+regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity. Proc. Natl. Acad. Sci. USA 2005. 102: 17418-17423.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17418-17423
    • Stephens, L.A.1    Gray, D.2    Anderton, S.M.3
  • 21
    • 73249117794 scopus 로고    scopus 로고
    • Thymocyte deletion can bias Treg formation toward low-abundance self-peptide
    • Picca, C. C., Oh, S., Panarey, L., Aitken, M., Basehoar, A. and Caton, A. J., Thymocyte deletion can bias Treg formation toward low-abundance self-peptide. Eur. J. Immunol. 2009. 39: 3301-3306.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 3301-3306
    • Picca, C.C.1    Oh, S.2    Panarey, L.3    Aitken, M.4    Basehoar, A.5    Caton, A.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.