Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg)

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Szajnik, Marta ^b   Czystowska, Malgorzata ^b   Szczepanski, Miroslaw J ^b   Mandapathil, Magis ^b   Whiteside, Theresa L ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; FAS LIGAND; GRANZYME B; INTERLEUKIN 10; NEUTRALIZING ANTIBODY; PERFORIN; PROTEIN CTLA4; SMAD2 PROTEIN; SMAD3 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CD3 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA;

APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXOSOME; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOLECULAR INTERACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR CELL; TUMOR GROWTH; UPREGULATION; CD4+ T LYMPHOCYTE; CYTOPLASM VESICLE; FLOW CYTOMETRY; METABOLISM; PHYSIOLOGY; TUMOR CELL CULTURE; TUMOR CELL LINE; WESTERN BLOTTING;

TOBACCO MOSAIC VIRUS;

ANTIGENS, CD3; APOPTOSIS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOPLASMIC VESICLES; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; T-LYMPHOCYTES, REGULATORY; TUMOR CELLS, CULTURED;

EID: 77955406553     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011469     Document Type: Article

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