Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging

Aging Cell

Volumn 12, Issue 1, 2013, Pages 156-166

  Delaney, Joe R ^a   Ahmed, Umema ^a   Chou, Annie ^a   Sim, Sylvia ^a   Carr, Daniel ^a   Murakami, Christopher J ^a   Schleit, Jennifer ^a   Sutphin, George L ^a   An, Elroy H ^a   Castanza, Anthony ^a   Fletcher, Marissa ^a   Higgins, Sean ^a   Jelic, Monika ^a   Klum, Shannon ^a   Muller, Brian ^a   Peng, Zhao J ^a   Rai, Dilreet ^a   Ros, Vanessa ^a   Singh, Minnie ^a   Wende, Helen V ^a   Kennedy, Brian K ^b,c   Kaeberlein, Matt ^a,c   more..

^a UNIVERSITY OF WASHINGTON   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Epistasis; ER stress; Longevity; Mitochondria; Phenotype mapping; Replicative lifespan; Stress response; Translation; Yeast

Indexed keywords

MESSENGER RNA; MITOCHONDRIAL PROTEIN; PROTEIN AFG3; RIBOSOME PROTEIN; TRANSCRIPTION FACTOR GCN4; TUNICAMYCIN; UNCLASSIFIED DRUG;

AGING; ARTICLE; BIOACCUMULATION; CYTOPLASM; CYTOSOL; DNA DAMAGE; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; FUNGAL STRAIN; LONGEVITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RNA TRANSLATION; UNFOLDED PROTEIN RESPONSE; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; AGE FACTORS; CYTOSOL; LONGEVITY; MITOCHONDRIA; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 84872598776     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12032     Document Type: Article

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