Direct selection for paraquat resistance in Drosophila results in a different extended longevity phenotype

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 56, Issue 10, 2001, Pages

  Vettraino, J ^a   Buck, S ^a   Arking, R ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; LIPID; PARAQUAT; PROTEIN;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENERGY METABOLISM; ENZYME ACTIVITY; FEMALE; LETHALITY; LONGEVITY; MALE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL;

ANIMALIA;

EID: 0034787025     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/56.10.B415     Document Type: Article

References (48)

1. Aging: A theory based on free radical and radiation chemistry
2. Effect of ethoxyquin on the longevity of C3H mice
3. A new outlook for anti-oxidant defense system
4. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
5. Extension of Drosophila life-span by overexpression of human SOD1 in motorneurons
6. FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
7. A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila
8. Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns
9. Gene expression and regulation in the extended longevity phenotypes of Drosophila
10. Comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities
11. Selection for delayed senescence in Drosophila melanogaster
12. Successful selection for increased longevity in Drosophila: Analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity
13. Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila
14. Selection for increased longevity in Drosophila melanogaster: A reply to Lints
15. Paraquat selection identifies X-linked oxygen defense genes in Drosophila melanogaster
16. Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster and identification of a novel behavioral mutant with a Shaker phenotype
17. A novel leg-shaking Drosophila mutant defective in a voltage-gated K+ current and hypersensitive to reactive oxygen species
18. The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase
19. Purification and properties of superoxide dismutases from Drosophila melanogaster
20. A simple method for determination of serum catalase activity and revision of reference range
21. Genetics of catalase in Drosophila melanogaster: Rates of synthesis and degradation of the enzyme in flies aneuploid and euploid for the structural gene
22. The genetics of catalase in Drosophila melanogaster: Isolation and characterization of acatalasemic mutants
23. The carbon monoxide-binding pigment of liver microsomes: I. Evidence for its hemoprotein nature
24. The measurement of difference spectra: Application to the cytochromes of microsomes
25. Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes. Reinvestigation of assay conditions
26. Involvement of cytochrome P450 in hostplant utilization by Sonoran desert Drosophila
27. Extended longevity in Drosophila is consistently associated with a decrease in developmental viability
28. The genetics of catalase in Drosphila melanogaster: Isolation and characterization of acatalasemic mutants
29. Inhibition of cytochrome P450 enzymes by the eye pigments in D. mojavensis
30. Evaluation of chemicals as inhibitors of trout cytochrome P450s
31. Cytochrome P450-mediated resistance to isoquinoline alkaloids and susceptibility to synthetic insecticides in Drosophila
32. The molecular basis of adaptation in Drosophila: The role of cytochrome P4505
33. Cellular response to cancer chemopreventive agents: Contribution of the antioxidant response element to the adaptive response to oxidative and chemical stress
34. Causes and consequences of variation in energy storage in Drosophila
35. Adaptive response to environmental chemicals
36. The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
37. Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
38. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage and longevity in different species of flies
39. Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila
40. Longevity and aging: Beneficial effects of exposure to mild stress
41. Inherited stress resistance and longevity: A stress theory of aging
42. Selection on stress resistance increases longevity in Drosophila melanogaster
43. Aging and resistance to oxidative damage in Caenorhabditis elegans
44. A cytosolic catalase is needed to extend adult life span in C. elegans daf-C and clk-1 mutants
45. Hypothesis: Interventions that increase the response to stress offer the potential for effective life prolongation and increased health
46. Stress resistance and longevity in selected lines of Drosophila melanogaster
47. Drosophila selected for extended longevity are more sensitive to heat shock