Endogenous extracellular HSP72 release is an adaptive feature of the acute stress response

Psychoneuroimmunology, Two-Volume Set

Volumn 2, Issue , 2007, Pages 1013-1034

  Fleshner, Monika ^a   Sharkey, Craig M ^a   Nickerson, Molly ^a   Johnson, John D ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882473034     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012088576-3/50055-1     Document Type: Chapter

References (198)

1. Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunology 2001, 2:675-680.
2. Ali H., Haribabu B., Richardson R.M., Snyderman R. Mechanisms of inflammation and leukocyte activation. Med. Clin. North Am. 1997, 81:1-28.
3. Arieli Y., Eynan M., Gancz H., Arieli R., Kashi Y. Heat acclimation prolongs the time to central nervous system oxygen toxicity in the rat. Possible involvement of Hsp72. Brain Res. 2003, 962:15-20.
4. Arnold-Schild D., Hanau D., Spehner D., Schmid C., Rammensee H.G., de la Salle H., Schild H. Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells. J. Immunol. 1999, 162:3757-3760.
5. Asea A., Kabingu E., Stevenson M.A., Calderwood S.K. Hsp70 peptide-bearing and peptide-negative preparations act as chaperokines. Cell Stress Chaperones 2000, 5:425-431.
6. Asea A., Kraeft S.K., Kurt-Jones E.A., Stevenson M.A., Chen L.B., Finberg R.W., Koo G.C., Calderwood S.K. Hsp70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 2000, 6:435-442.
7. Asea A., Rehli M., Kabingu E., Boch J.A., Bare O., Auron P.E., Stevenson M.A., Calderwood S.K. Novel signal transduction pathway utilized by extracellular Hsp70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 2002, 277:15028-15034.
8. Avitsur R., Padgett D.A., Dhabhar F.S., Stark J.L., Kramer K.A., Engler H., Sheridan J.F. Expression of glucocorticoid resistance following social stress requires a second signal. J. Leukoc. Biol. 2003, 74:507-513.
9. Barrientos R.M., O'Reilly R.C., Rudy J.W. Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav. Brain Res. 2002, 134:299-306.
10. Basu S., Binder R.J., Suto R., Anderson K.M., Srivastava P.K. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a PARTial maturation signal to dendritic cells and activate the NF-kappa B p. Int. Immunol. 2000, 12:1539-1546.
11. Baumann H., Gauldie J. The acute phase response. Immunol. Today 1994, 15:74-80.
12. Bellingan G.J., Caldwell H., Howie S.E., Dransfield I., Haslett C. In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining l. J. Immunol. 1996, 157:2577-2585.
13. Berwin B., Reed R.C., Nicchitta C.V. Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96. J. Biol. Chem. 2001, 276:21083-21088.
14. Bethke K., Staib F., Distler M., Schmitt U., Jonuleit H., Enk A.H., Galle P.R., Heike M. Different efficiency of heat shock proteins (Hsp) to activate human monocytes and dendritic cells: superiority of Hsp60. J. Immunol. 2002, 169:6141-6148.
15. Blake M.J., Buckley A.R., LaVoi K.P., Bartlett T. Neural and endocrine mechanisms of cocaine-induced 70k-Da heat shock protein expression in aorta and adrenal gland. Journal of Pharmacological Experimental Therapy 1994, 268:522-529.
16. Blake M.J., Udelsman R., Feulner G.J., Norton D.D., Holbrook N.J. Stress-induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormonesensitive, age-dependent response. Proc. Natl. Acad. Sci. USA 1991, 88:9873-9877.
17. Breloer M., Dorner B., More S.H., Roderian T., Fleischer B., von Bonin A. Heat shock proteins as "danger signals": eukaryotic Hsp60 enhances and accelerates antigen-specific IFNgamma production in T cells. Eur. J. Immunol. 2001, 31:2051-2059.
18. Broquet A.H., Thomas G., Masliah J., Trugnan G., Bachelet M. Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J. Biol. Chem. 2003, 278:21601-21606.
19. Cacioppo J.T., Berntson G.G., Malarkey W.B., Kiecolt-Glaser J.K., Sheridan J.F., Poehlmann K.M., Burleson M.H., Ernst J.M., Hawkley L.C., Glaser R. Autonomic, neuroendocrine, and immune responses to psychological stress: the reactivity hypothesis. Ann. N. Y. Acad. Sci. 1998, 840:664-673.
20. Cahill C.M., Lin H.S., Price B.D., Bruce J.L., Calderwood S.K. Potential role of heat shock transcription factor in the expression of inflammatory cytokines. Adv. Exp. Med. Biol. 1997, 400:625-630.
21. Cahill C.M., Waterman W.R., Xie Y., Auron P.E., Calderwood S.K. Transcriptional repression of the prointerleukin 1beta gene by heat shock factor 1. J. Biol. Chem. 1996, 271:24874-24879.
22. Campisi J., Fleshner M. The role of extracellular Hsp72 in acute stress-induced potentiation of innate immunity in physically active rats. Journal of Applied Physiology 2003, 94:43-52.
23. Campisi J., Leem T.H., Fleshner M. Acute stress decreases inflammation at the site of infection. A role for nitric oxide. Physiology and Behavior 2002, 77:291-299.
24. Campisi J., Leem T.H., Fleshner M. Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system. Cell, Stress and Chaperones 2003, 8:272-286.
25. Campisi J., Leem T.H., Greenwood B.N., Hansen M.K., Moraska A., Higgins K., Smith T.P., Fleshner M. Habitual physical activity facilitates stress-induced Hsp72 induction in brain, peripheral and immune tissues. American Journal of Physiology 2003, 284:520-530.
26. Cannon B., Jacobsson A., Rehnmark S., Nedergaard J. Signal transduction in brown adipose tissue recruitment: noradrenaline and beyond. Int. J. Obes. Relat. Metab. Disord. 1996, 20. S36-S42.
27. Carrasco G.A., Van de Kar L.D. Neuroendocrine pharmacology of stress. Eur. J. Pharmacol. 2003, 463:235-272.
28. Chen W., Syldath U., Bellmann K., Burkart V., Kolb H. Human 60-kDa heat-shock protein: a danger signal to the innate immune system. J. Immunol. 1999, 162:3212-3219.
29. Christou E.A., Jakobi J., Critchlow A., Fleshner M., Enoka R. The 1-2 Hz oscillations in force are exacerbated by stress, especially in older adults. J. Appl. Phys. 2004, 97:225-235.
30. Ciocca D.R., Calderwood S.K. Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 2005, 10:86-103.
31. Clayton A., Turkes A., Navabi H., Mason M.D., Tabi Z. Induction of heat shock proteins in B-cell exosomes. J. Cell Sci. 2005, 118:3631-3638.
32. Coe C.L., Rosenberg L.T., Levine S. Effect of maternal separation on the complement system and antibody responses in infant primates. Int. J. Neurosci. 1988, 40:289-302.
33. Colaco C.A. Towards a unified theory of immunity: dendritic cells, stress proteins and antigen capture. Cell Mol. Biol. (Noisy-le-grand) 1998, 44:883-890.
34. Collins S., Surwit R.S. The beta-adrenergic receptors and the control of adipose tissue metabolism and thermogenesis. Recent. Prog. Horm. Res. 2001, 56:309-328.
35. Coussons-Read M.E., Maslonek K.A., Fecho K., Perez L., Lysle D.T. Evidence for the involvement of macrophagederived nitric oxide in the modulation of immune status by a conditioned aversive stimulus. J. Neuroimmunol. 1994, 50:51-58.
36. Cvoro A., Matic G. Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor. Int. J. Biochem. Cell Biol. 2002, 34:279-285.
37. Deak T., Meriwether J.L., Fleshner M., Spencer R.L., Abouhamze A., Moldawer L.L., Grahn R.E., Watkins L.R., Maier S.F. Evidence that brief stress may induce the acute phase response in rats. Am. J. Physiol. 1997, 273. R1998-R2004.
38. Deak T., Nguyen K.T., Fleshner M., Watkins L.R., Maier S.F. Acute stress may facilitate recovery from a subcutaneous bacterial challenge. Neuroimmunomodulation 1999, 6:344-354.
39. Deitch E.A., Berg R. Bacterial translocation from the gut: a mechanism of infection. J. Burn. Care. Rehabil. 1987, 8:475-482.
40. Del Bino G., Darzynkiewicz Z., Degraef C., Mosselmans R., Fokan D., Galand P. Comparison of methods based on annexin-V binding, DNA content or TUNEL for evaluating cell death in HL-60 and adherent MCF-7 cells. Cell Prolif. 1999, 32:25-37.
41. Diamond D.M., Park C.R., Heman K.L., Rose G.M. Exposing rats to a predator impairs spatial working memory in the radial arm water maze. Hippocampus 1999, 9:542-552.
42. Dinarello C.A. Proinflammatory cytokines. Chest. 2000, 118:503-508.
43. Ding X.Z., Fernandez-Prada C.M., Bhattacharjee A.K., Hoover D.L. Overexpression of Hsp-70 inhibits bacterial lipopolysaccharide-induced production of cytokines in human monocyte-derived macrophages. Cytokine 2001, 16:210-219.
44. Febbraio M.A., Koukoulas I. Hsp72 gene expression progressively increases in human skeletal muscle during prolonged, exhaustive exercise. J. Appl. Physiol. 2000, 89:1055-1060.
45. Febbraio M.A., Ott P., Nielsen H.B., Steensberg A., Keller C., Krustrup P., Secher N.H., Pedersen B.K. Exercise induces hepatosplanchnic release of heat shock protein 72 in humans. J. Physiol. 2002, 544:957-962.
46. Febbraio M.A., Steensberg A., Walsh R., Koukoulas I., van Hall G., Saltin B., Pedersen B.K. Reduced glycogen availability is associated with an elevation in Hsp72 in contracting human skeletal muscle. J. Physiol. 2002, 538:911-917.
47. Fecho K., Maslonek K.A., Coussons-Read M.E., Dykstra L.A., Lysle D.T. Macrophage-derived nitric oxide is involved in the depressed concanavalin A responsiveness of splenic lymphocytes from rats administered morphine in vivo. J. Immunol. 1994, 152:5845-5852.
48. Fleshner M., Campisi J., Amiri L., Diamond D.M. Cat exposure induces both intra & extra-cellular Hsp72: the role of adrenal hormones. Psychoneuroendocrinology 2004, 29:1142-1152.
49. Fleshner M., Campisi J., Deak T., Greenwood B.N., Kintzel J.A., Leem T.H., Smith T.P., Sorensen B. Acute stressor exposure facilitates innate immunity more in physically active than in sedentary rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 282. R1680-R1686.
50. Fleshner M., Campisi J., Johnson J.D. Can exercise stress facilitate innate immunity? A functional role for stressinduced extracellular Hsp72. Exercise Immunology Review 2003, 9:6-24.
51. Fleshner M., Deak T., Spencer R.L., Laudenslauger M.L., Watkins L.R., Maier S.F. A long term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure. Endocrinology 1995, 136:5336-5342.
52. Fleshner M., Johnson J.D. Exogenous extra-cellular heat shock protein 72: releasing signal (s) and function. International Journal of Hyperthermia 2005, 21:457-471.
53. Fleshner M., Nguyen K.T., Cotter C.S., Watkins L.R., Maier S.F. Acute stressor exposure both suppresses acquired immunity and potentiates innate immunity. Am. J. Physiol. 1998, 275:R870-R878.
54. Fleshner M., Pugh C.R., Tremblay D., Rudy J.W. DHEA-S selectively impairs contextual-fear conditioning: support for the antiglucocorticoid hypothesis. Behav. Neurosci. 1997, 111:512-517.
55. Foster D.O., Depocas F., Zaror-Behrens G. Unilaterality of the sympathetic innervation of each pad of rat interscapular brown adipose tissue. Can. J. Physiol. Pharmacol. 1982, 60:107-113.
56. Foster D.O., Depocas F., Zuker M. Heterogeneity of the sympathetic innervation of rat interscapular brown adipose tissue via intercostal nerves. Can. J. Physiol. Pharmacol. 1982, 60:747-754.
57. Gallucci S., Lolkema M., Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 1999, 5:1249-1255.
58. Gao B., Tsan M.F. Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release. J. Biol. Chem. 2003, 278:174-179.
59. Gao B., Tsan M.F. Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J. Biol. Chem. 2003, 278:22523-22529.
60. Gastpar R., Gehrmann M., Bausero M.A., Asea A., Gross C., Schroeder J.A., Multhoff G. Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. Cancer Res. 2005, 65:5238-5247.
61. Granneman J.G., Zhai Y., Lahners K.N. Selective upregulation of alpha1a-adrenergic receptor protein and mRNA in brown adipose tissue by neural and beta3-adrenergic stimulation. Mol. Pharmacol. 1997, 51:644-650.
62. Greenwood B.N., Kennedy S., Smith T.P., Campeau S., Day H.E., Fleshner M. Voluntary freewheel running selectively modulates catecholamine content in peripheral tissue and c-Fos expression in the central sympathetic circuit following. Neuroscience 2003, 120:269-281.
63. Gross C., Hansch D., Gastpar R., Multhoff G. Interaction of heat shock protein 70 peptide with NK cells involves the NK receptor CD94. Biol. Chem. 2003, 384:267-279.
64. Gulati N., Huggel H., Gulati O.P. Effect of labetalol on adrenoceptors in the isolated perfused rat mesentery. Arch. Int. Pharmacodyn. Ther. 1980, 246:251-256.
65. Guzhova I., Kislyakova K., Moskaliova O., Fridlanskaya I., Tytell M., Cheetham M., Margulis B. In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance. Brain Res. 2001, 914:66-73.
66. Habich C., Baumgart K., Kolb H., Burkart V. The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins. J. Immunol. 2002, 168:569-576.
67. Hamilton K.L., Staib J.L., Phillips T., Hess A., Lennon S.L., Powers S.K. Exercise, antioxidants, and Hsp72: protection against myocardial ischemia/reperfusion. Free Radic. Biol. Med. 2003, 34:800-809.
68. Hammill A.K., Uhr J.W., Scheuermann R.H. Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. Exp. Cell Res. 1999, 251:16-21.
69. Hardman J.G., Limbird L.E. Goodman & Gilman's: The pharmacological basis of therapeutics 2001, McGraw-Hill, New York. 10th ed.
70. Harmsen A.G., Turney T.H. Inhibition of in vivo neutrophil accumulation by stress. Possible role of neutrophil adherence. Inflammation 1985, 9:9-20.
71. Hartl F.U. Molecular chaperones in cellular protein folding. Nature 1996, 381:571-579.
72. Heine H., Lien E. Toll-like receptors and their function in innate and adaptive immunity. Int. Arch. Allergy. Immunol. 2003, 130:180-192.
73. Heneka M.T., Gavrilyuk V., Landreth G.E., O'Banion M.K., Weinberg G., Feinstein D.L. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and Hsp70 expression. J. Neurochem. 2003, 85:387-398.
74. Hessman Y., Rentzhog L., Ekbohm G. Effect of adrenal demedullation on urinary excretion of catecholamines in thermal trauma in rats. Acta. Chir. Scand. 1976, 142:291-295.
75. Hickman-Miller H.D., Hildebrand W.H. The immune response under stress: the role of Hsp-derived peptides. Trends. Immunol. 2004, 25:427-433.
76. Hightower L.E., Guidon P.T. Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins. J. Cell Physiol. 1989, 138:257-266.
77. Honda O., Kuroda M., Joja I., Asaumi J., Takeda Y., Akaki S., Togami I., Kanazawa S., Kawasaki S., Hiraki Y. Assessment of secondary necrosis of Jurkat cells using a new microscopic system and double staining method with annexin V and propidium iodide. Int. J. Oncol. 2000, 16:283-288.
78. Horton J.W. Bacterial translocation after burn injury: the contribution of ischemia and permeability changes. Shock 1994, 1:286-290.
79. Housby J.N., Cahill C.M., Chu B., Prevelige R., Bickford K., Stevenson M.A., Calderwood S.K. Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce Hsp70 in human monocytes. Cytokine. 1999, 11:347-358.
80. Ianaro A., Ialenti A., Maffia P., Pisano B., Di Rosa M. HSF1/hsp72 pathway as an endogenous anti-inflammatory system. FEBS Lett. 2001, 499:239-244.
81. Ianaro A., O'Donnell C.A., Di Rosa M., Liew F.Y. A nitric oxide synthase inhibitor reduces inflammation, downregulates inflammatory cytokines and enhances interleukin-10 production in carrageenin-induced oed. Immunology. 1994, 82:370-375.
82. Janeway C.A., Jr.Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002, 20:197-216.
83. Johnson G.B., Brunn G.J., Tang A.H., Platt J.L. Evolutionary clues to the functions of the Toll-like family as surveillance receptors. Trends Immunol. 2003, 24:19-24.
84. Johnson J.D., Campisi J., Sharkey C.M., Kennedy S., Nickerson M., Fleshner M. Adrenergic receptors mediate stressinduced elevation in endogenous extracellular Hsp72. Journal of Applied Physiology 2005, 99(5):1789-1795.
85. Johnson J.D., Fleshner M. Releasing signals, secretory pathways and immunological function of endogenous extracellular Hsp72. Journal of Leukocyte Biology 2006, 79(3):425-434.
86. Johnson J.D., O'Connor K.A., Deak T., Spencer R.L., Watkins L.R., Maier S.F. Prior stressor exposure primes the HPA axis. Psychoneuroendocrinology 2002, 27:353-365.
87. Johnson J.D., O'Connor K.A., Deak T., Stark M., Watkins L.R., Maier S.F. Prior stressor exposure sensitizes LPSinduced cytokine production. Brain Behav. Immun. 2002, 16:461-476.
88. Johnson J.D., O'Connor K.A., Hansen M.K., Watkins L.R., Maier S.F. Effects of prior stress on LPS-induced cytokine and sickness responses. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 284:422-432.
89. Katafuchi T., Takaki A., Take S., Kondo T., Yoshimura M. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res. Mol. Brain Res. 2003, 118:24-32.
90. Kaufmann S.H. Heat shock proteins and the immune response. Immunol. Today 1990, 11:129-136.
91. Kaufmann S.H. Heat-shock proteins: a link between rheumatoid arthritis and infection?. Curr. Opin. Rheumatol. 1990, 2:430-435.
92. Kelly S., Zhang Z.J., Zhao H., Xu L., Giffard R.G., Sapolsky R.M., Yenari M.A., Steinberg G.K. Gene transfer of Hsp72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: influence of Bcl-2. Ann. Neurol. 2002, 52:160-167.
93. Kikuchi-Utsumi K., Kikuchi-Utsumi M., Cannon B., Nedergaard J. Differential regulation of the expression of alpha1-adrenergic receptor subtype genes in brown adipose tissue. Biochem. J. 1997, 322:417-424. (Pt 2).
94. King Y.T., Lin C.S., Lin J.H., Lee W.C. Whole-body hyperthermia-induced thermotolerance is associated with the induction of heat shock protein 70 in mice. J. Exp. Biol. 2002, 205:273-278.
95. Kol A., Lichtman A.H., Finberg R.W., Libby P., Kurt-Jones E.A. Cutting edge: heat shock protein (Hsp) 60 activates the innate immune response: CD14 is an essential receptor for Hsp60 activation of mononuclear cells. J. Immunol. 2000, 164:13-17.
96. Kregel K.C. Invited review: heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J. Appl. Physiol. 2002, 92:2177-2186.
97. Kregel K.C., Moseley P.L. Differential effects of exercise and heat stress on liver Hsp70 accumulation with aging. J. Appl. Physiol. 1996, 80:547-551.
98. Krishnaswamy G., Kelley J., Yerra L., Smith J.K., Chi D.S. Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease. J. Interferon Cytokine Res. 1999, 19:91-104.
99. Lancaster G.I., Febbraio M.A. Exosome-dependent trafficking of Hsp70: a novel secretory pathway for cellular stress proteins. J. Biol. Chem. 2005, 280:23349-23355.
100. Lecoeur H., Prevost M.C., Gougeon M.L. Oncosis is associated with exposure of phosphatidylserine residues on the outside layer of the plasma membrane: a reconsideration of the specificity of the an. Cytometry. 2001, 44:65-72.
101. Lehner T., Bergmeier L.A., Wang Y., Tao L., Sing M., Spallek R., van der Zee R. Heat shock proteins generate betachemokines which function as innate adjuvants enhancing adaptive immunity. Eur. J. Immunol. 2000, 30:594-603.
102. Lehner T., Wang Y., Whittall T., McGowan E., Kelly C.G., Singh M. Functional domains of Hsp70 stimulate generation of cytokines and chemokines, maturation of dendritic cells and adjuvanticity. Biochem. Soc. Trans. 2004, 32:629-632.
103. Lewthwaite J., Owen N., Coates A., Henderson B., Steptoe A. Circulating human heat shock protein 60 in the plasma of British civil servants: relationship to physiological and psychosocial stress. Circulation 2002, 106:196-201.
104. Lindquist S., Craig E.A. The heat-shock proteins. Annu. Rev. Genet. 1988, 22:631-677.
105. Liu T.S., Musch M.W., Sugi K., Walsh-Reitz M.M., Ropeleski M.J., Hendrickson B.A., Pothoulakis C., Lamont J.T., Chang E.B. Protective role of Hsp72 against Clostridium difficile toxin A-induced intestinal epithelial cell dysfunction. Am. J. Physiol. Cell Physiol. 2003, 284:C1073-C1082.
106. Lucas M., Rose P.E., Morris A.G. Contrasting effects of Hsp72 expression on apoptosis in human umbilical vein endothelial cells and an angiogenic cell line, ECV304. Br. J. Haematol. 2000, 110:957-964.
107. Lysle D.T., Fecho K., Maslonek K.A., Dykstra L.A. Evidence for the involvement of macrophage-derived nitric oxide in the immunomodulatory effect of morphine and aversive Pavlovian conditioning. Adv. Exp. Med. Biol. 1995, 373:141-147.
108. Lyte M., Ernst S. Catecholamine induced growth of gram negative bacteria. Life Sciences 1991, 50:203-212.
109. Lyte M., Nelson S.G., Thompson M.L. Innate and adaptive immune responses in a social conflict paradigm. Clin. Immunol. Immunopathol. 1990, 57:137-147.
110. Lyte M., Nguyen K.T. Alteration of Escherichia coli O157:H7 growth and molecular fingerprint by the neuroendocrine hormone noradrenaline. Microbios 1997, 89:197-213.
111. Mac Micking J., Xie Q.W., Nathan C. Nitric oxide and macrophage function. Annual Review of Immunology 1997, 15:323-350.
112. Maloyan A., Horowitz M. Beta-adrenergic signaling and thyroid hormones affect Hsp72 expression during heat acclimation. J. Appl. Physiol. 2002, 93:107-115.
113. Mao H., Li F., Ruchalski K., Mosser D.D., Schwartz J.H., Wang Y., Borkan S.C. Hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells. J. Biol. Chem. 2003, 278:18214-18220.
114. Martin C.A., Carsons S.E., Kowalewski R., Bernstein D., Valentino M., Santiago-Schwarz F. Aberrant extracellular and dendritic cell (DC) surface expression of heat shock protein (hsp) 70 in the rheumatoid joint: possible mechanisms of hsp/DC-mediat. J. Immunol. 2003, 171:5736-5742.
115. Martin U., Roemer D. Ketotifen: a histamine release inhibitor. Monogr. Allergy 1977, 12:145-149.
116. Matz J.M., LaVoi K.P., Blake M.J. Adrenergic regulation of the heat shock response in brown adipose tissue. J. Pharmacol. Exp. Ther. 1996, 277:1751-1758.
117. Matz J.M., LaVoi K.P., Moen R.J., Blake M.J. Coldinduced heat shock protein expression in rat aorta and brown adipose tissue. Physiol. Behav. 1996, 60:1369-1374.
118. Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 1994, 12:991-1045.
119. Matzinger P. An innate sense of danger. Semin. Immunol. 1998, 10:399-415.
120. McLeish K.R., Dean W.L., Wellhausen S.R., Stelzer G.T. Role of intracellular calcium in priming of human peripheral blood monocytes by bacterial lipopolysaccharide. Inflammation 1989, 13:681-692.
121. Mesches M.H., Fleshner M., Heman K.L., Rose G.M., Diamond D.M. Exposing rats to a predator blocks primed burst potentiation in the hippocampus in vitro. J. Neurosci. 1999, 19:RC18.
122. Moraska A., Campisi J., Nguyen K.T., Maier S.F., Watkins L.R., Fleshner M. Elevated IL-1beta contributes to antibody suppression produced by stress. J. Appl. Physiol. 2002, 93:207-215.
123. Morimoto R.I. The biology of heat shock proteins and molecular chaperones 1994, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
124. Morimoto R.I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes. Dev. 1998, 12:3788-3796.
125. Moseley P.L. Heat shock proteins and the inflammatory response. Ann. N. Y. Acad. Sci. 1998, 856:206-213.
126. Multhoff G. Activation of natural killer cells by heat shock protein 70. Int. J. Hyperthermia. 2002, 18:576-585.
127. Multhoff G., Botzler C. Heat-shock proteins and the immune response. Ann. N. Y. Acad. Sci. 1998, 851:86-93.
128. Multhoff G., Botzler C., Wiesnet M., Muller E., Meier T., Wilmanns W., Issels R.D. A stress-inducible 72-kDa heat-shock protein (Hsp72) is expressed on the surface of human tumor cells, but not on normal cells. Int. J. Cancer 1995, 61:272-279.
129. Multhoff G., Mizzen L., Winchester C.C., Milner C.M., Wenk S., Eissner G., Kampinga H.H., Laumbacher B., Johnson J. Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells. Exp. Hematol. 1999, 27:1627-1636.
130. Multhoff G., Pfister K., Gehrmann M., Hantschel M., Gross C., Hafner M., Hiddemann W. A 14-mer Hsp70 peptide stimulates natural killer (NK) cell activity. Cell Stress Chaperones 2001, 6:337-344.
131. Nazli A., Yang P.C., Jury J., Howe K., Watson J.L., Soderholm J.D., Sherman P.M., Perdue M.H., McKay D.M. Epithelia under metabolic stress perceive commensal bacteria as a threat. Am. J. Pathol. 2004, 164:947-957.
132. Nettelbladt C.G., Katouli M., Bark T., Svenberg T., Mollby R., Ljungqvist O. Orally inoculated Escherichia coli strains colonize the gut and increase bacterial translocation after stress in rats. Shock 2003, 20:251-256.
133. Ohashi K., Burkart V., Flohe S., Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 2000, 164:558-561.
134. Panjwani N.N., Popova L., Srivastava P.K. Heat shock proteins gp96 and Hsp70 activate the release of nitric oxide by APCs. J. Immunol. 2002, 168:2997-3003.
135. Park C.R., Campbell A.M., Diamond D.M. Chronic psychosocial stress impairs learning and memory and increases sensitivity to yohimbine in adult rats. Biol. Psychiatry 2001, 50:994-1004.
136. Paroo Z., Dipchand E.S., Noble E.G. Estrogen attenuates postexercise Hsp70 expression in skeletal muscle. Am. J. Physiol. Cell Physiol. 2002, 282:C245-C251.
137. Paroo Z., Haist J.V., Karmazyn M., Noble E.G. Exercise improves postischemic cardiac function in males but not females: consequences of a novel sex-specific heat shock protein 70 response. Circ. Res. 2002, 90:911-917.
138. Paroo Z., Noble E.G. Isoproterenol potentiates exerciseinduction of Hsp70 in cardiac and skeletal muscle. Cell Stress Chaperones 1999, 4:199-204.
139. Paroo Z., Tiidus P.M., Noble E.G. Estrogen attenuates Hsp72 expression in acutely exercised male rodents. Eur. J. Appl. Physiol. Occup. Physiol. 1999, 80:180-184.
140. Paterson H.M., Murphy T.J., Purcell E.J., Shelley O., Kriynovich S.J., Lien E., Mannick J.A., Lederer J.A. Injury primes the innate immune system for enhanced Toll-like receptor reactivity. J. Immunol. 2003, 171:1473-1483.
141. Pirkkala L., Nykanen P., Sistonen L. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J. 2001, 15:1118-1131.
142. Pittet J.F., Lee H., Morabito D., Howard M.B., Welch W.J., Mackersie R.C. Serum levels of Hsp 72 measured early after trauma correlate with survival. J. Trauma. 2002, 52:611-617.
143. Pockley A.G. Heat shock proteins as regulators of the immune response. Lancet 2003, 362:469-476.
144. Pockley A.G., De Faire U., Kiessling R., Lemne C., Thulin T., Frostegard J. Circulating heat shock protein and heat shock protein antibody levels in established hypertension. J. Hypertens. 2002, 20:1815-1820.
145. Pockley A.G., GAdes A., Thulin T., de Faire U., Frostegard J. Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension. Hypertension 2003, 42:235-238.
146. Prohaszka Z., Fust G. Immunological aspects of heatshock proteins-the optimum stress of life. Mol. Immunol. 2004, 41:29-44.
147. Prohaszka Z., Singh M., Nagy K., Kiss E., Lakos G., Duba J., Fust G. Heat shock protein 70 is a potent activator of the human complement system. Cell Stress Chaperones 2002, 7:17-22.
148. Pugh C.R., Fleshner M., Tremblay D., Rudy J.W. A selective role for corticosterone in contextual fear conditioning. Behavioral Neuroscience 1997, 111:503-511.
149. Quintana F.J., Cohen I.R. Heat shock proteins as endogenous adjuvants in sterile and septic inflammation. J. Immunol. 2005, 175:2777-2782.
150. Raasmaja A., Mohell N., Nedergaard J. Increased alpha 1-adrenergic receptor density in brown adipose tissue of coldacclimated rats and hamsters. Eur. J. Pharmacol. 1984, 106:489-498.
151. Rea I.M., McNerlan S., Pockley A.G. Serum heat shock protein and anti-heat shock protein antibody levels in aging. Exp. Gerontol. 2001, 36:341-352.
152. Redaelli C.A., Wagner M., Kulli C., Tian Y.H., Kubulus D., Mazzucchelli L., Wagner A.C., Schilling M.K. Hyperthermia-induced Hsp expression correlates with improved rat renal isograft viability and survival in kidneys harvested from non-heart-beating donors. Transpl. Int. 2001, 14:351-360.
153. Reed R.C., Nicchitta C.V. Chaperone-mediated crosspriming: a hitchhiker's guide to vesicle transport (review). Int. J. Mol. Med. 2000, 6:259-264.
154. Ritossa F. A new puffing pattern induced by temperature shock and DNP in. Drosophila. Experientia. 1962, 15:571-573.
155. Ruchalski K., Mao H., Singh S.K., Wang Y.D., Mosser D., Li F.H., Schwartz J.H., Borkan S.C. Hsp72 inhibits apoptosis-inducing factor release in ATP depleted renal epithelial cells. Am. J. Physiol. Cell Physiol. 2003, 285:1483-1493.
156. Rudy J.W. Contextual conditioning and auditory cue conditioning dissociate during development. Behav. Neurosci. 1993, 107:887-891.
157. Rudy J.W. Ontogeny of context-specific latent inhibition of conditioned fear: implications for configural associations theory and hippocampal formation development. Dev. Psychobiol. 1994, 27:367-379.
158. Rudy J.W., Morledge P. Ontogeny of contextual fear conditioning in rats: implications for consolidation, infantile amnesia, and hippocampal system function. Behav. Neurosci. 1994, 108:227-234.
159. Rudy J.W., O'Reilly R.C. Contextual fear conditioning, conjunctive representations, pattern completion, and the hippocampus. Behav. Neurosci. 1999, 113:867-880.
160. Santoro M.G. Heat shock factors and the control of the stress response. Biochem. Pharmacol. 2000, 59:55-63.
161. Sauter B., Albert M.L., Francisco L., Larsson M., Somersan S., Bhardwaj N. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory den. J. Exp. Med. 2000, 191:423-434.
162. Smith J.A., Pyne D.B. Exercise, training, and neutrophil function. Exerc. Immunol. Rev. 1997, 3:96-116.
163. Sondermann H., Becker T., Mayhew M., Wieland F., Hartl F.U. Characterization of a receptor for heat shock protein 70 on macrophages and monocytes. Biol. Chem. 2000, 381:1165-1174.
164. Srivastava P. Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Ann. Rev. Immunol. 2002, 20:395-425.
165. Srivastava P.K., Heike M. Tumor-specific immunogenicity of stress-induced proteins: convergence of two evolutionary pathways of antigen presentation?. Semin. Immunol. 1991, 3:57-64.
166. Sun L., Chang J., Kirchhoff S.R., Knowlton A.A. Activation of HSF and selective increase in heat-shock proteins by acute dexamethasone treatment. Am. J. Physiol. Heart Circ. Physiol. 2000, 278:H1091-H1097.
167. Takaki A., Huang Q.H., Somogyvari-Vigh A., Arimura A. Immobilization stress may increase plasma interleukin-6 via central and peripheral catecholamines. Neuroimmunomodulation 1994, 1:335-342.
168. Thomas G., Souil E., Richard M.J., Saunier B., Polla B.S., Bachelet M. Hyperthermia assists survival of astrocytes from oxidative-mediated necrotic cell death. Cell Mol. Biol. (Noisy-le-grand) 2002, 48:191-198.
169. Tissieres A., Mitchell H.K., Tracy U. Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. Journal of Molecular Biology 1974, 84:389-398.
170. Todryk S.M., Melcher A.A., Dalgleish A.G., Vile R.G. Heat shock proteins refine the danger theory. Immunology 2000, 99:334-337.
171. Tomioka H., Saito H. Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents. Journal of Leukocyte Biology 1992, 51:24-31.
172. Tsan M.F., Gao B. Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release. Journal of Biological Chemistry 2004, 278:174-179.
173. Udelsman R., Blake M.J., Holbrook N.J. Molecular response to surgical stress: specific and simultaneous heat shock protein induction in the adrenal cortex, aorta, and vena cava. Surgery 1991, 110:1125-1131.
174. Udelsman R., Blake M.J., Stagg C.A., Holbrook N.J. Endocrine control of stress-induced heat shock protein 70 expression in vivo. Surgery 1994, 115:611-616.
175. Udelsman R., Blake M.J., Stagg C.A., Li D.G., Putney D.J., Holbrook N.J. Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response. J. Clin. Invest. 1993, 91:465-473.
176. Udelsman R., Li D.G., Stagg C.A., Gordon C.B., Kvetnansky R. Adrenergic regulation of adrenal and aortic heat shock protein. Surgery 1994, 116:177-182.
177. Vabulas R.M., Ahmad-Nejad P., Ghose S., Kirschning C.J., Issels R.D., Wagner H. Hsp70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J. Biol. Chem. 2002, 277:15107-15112.
178. Valen G., Kawakami T., Tahepold P., Dumitrescu A., Lowbeer C., Vaage J. Glucocorticoid pretreatment protects cardiac function and induces cardiac heat shock protein 72. Am. J. Physiol. Heart Circ. Physiol. 2000, 279:H836-H843.
179. van Eden W., Koets A., van Kooten P., Prakken B., van der Zee R. Immunopotentiating heat shock proteins: negotiators between innate danger and control of autoimmunity. Vaccine 2003, 21:897-901.
180. van Eden W., van der Zee R., Paul A.G., Prakken B.J., Wendling U., Anderton S.M., Wauben M.H. Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases?. Immunol. Today 1998, 19:303-307.
181. van Eden W., van der Zee R., Prakken B. Heat-shock proteins induce T-cell regulation of chronic inflammation. Nat. Rev. Immunol. 2005, 5:318-330.
182. Velin A.K., Ericson A.C., Braaf Y., Wallon C., Soderholm J.D. Increased antigen and bacterial uptake in follicle associated epithelium induced by chronic psychological stress in rats. Gut 2004, 53:494-500.
183. Visintin A., Mazzoni A., Spitzer J.H., Wyllie D.H., Dower S.K., Segal D.M. Regulation of Toll-like receptors in human monocytes and dendritic cells. J. Immunol. 2001, 166:249-255.
184. Vollmer R.R., Meyers-Schoy S.A., Kolibal-Pegher S.S., Edwards D.J. The role of the adrenal medulla in neural control of blood pressure in rats. Clin. Exp. Hypertens. 1995, 17:649-667.
185. Walsh R.C., Koukoulas I., Garnham A., Moseley P.L., Hargreaves M., Febbraio M.A. Exercise increases serum Hsp72 in humans. Cell Stress Chaperones 2001, 6:386-393.
186. Wang Y., Kelly C.G., Karttunen J.T., Whittall T., Lehner P.J., Duncan L., MacAry P., Younson J.S., Singh M., Oehlmann W., Cheng G., Bergmeier L., Lehner T. CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines. Immunity 2001, 15:971-983.
187. Wang Y., Kelly C.G., Singh M., McGowan E.G., Carrara A.S., Bergmeier L.A., Lehner T. Stimulation of Th1-polarizing cytokines, C-C chemokines, maturation of dendritic cells, and adjuvant function by the peptide binding fragment of heat shock pr. J. Immunol. 2002, 169:2422-2429.
188. Wang Y., Whittall T., McGowan E., Younson J., Kelly C., Bergmeier L.A., Singh M., Lehner T. Identification of stimulating and inhibitory epitopes within the heat shock protein 70 molecule that modulate cytokine production and maturation of dendritic. J. Immunol. 2005, 174:3306-3316.
189. Wright B.H., Corton J.M., El-Nahas A.M., Wood R.F., Pockley A.G. Elevated levels of circulating heat shock protein 70 (Hsp70) in peripheral and renal vascular disease. Heart Vessels 2000, 15:18-22.
190. Wu B.J., Kingston R.E., Morimoto R.I. Human Hsp70 promoter contains at least two distinct regulatory domains. Proc. Natl. Acad. Sci. USA 1986, 83:629-633.
191. Wu C. Heat shock transcription factors: structure and regulation. Annu. Rev. Cell Dev. Biol. 1995, 11:441-469.
192. Xiao X., Zuo X., Davis A.A., McMillan D.R., Curry B.B., Richardson J.A., Benjamin I.J. HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice. Embo. J. 1999, 18:5943-5952.
193. Xie Y., Chen C., Stevenson M.A., Auron P.E., Calderwood S.K. Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J. Biol. Chem. 2002, 277:11802-11810.
194. Xie Y., Chen C., Stevenson M.A., Hume D.A., Auron P.E., Calderwood S.K. NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells. Biochem. Biophys. Res. Commun. 2002, 291:1071-1080.
195. Yokoyama H., Iinuma K., Yanai K., Watanabe T., Sakurai E., Onodera K. Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography. Methods Find Exp. Clin. Pharmacol. 1993, 15:183-188.
196. Yoo C.G., Lee S., Lee C.T., Kim Y.W., Han S.K., Shim Y.S. Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in resp. J. Immunol. 2000, 164:5416-5423.
197. Zidel Z., Masek K. Erratic behavior of nitric oxide within the immune system: illustrative review of conflicting data and their immunopharmacological aspects. International Journal of Immunopharmacology 1998, 20:319-343.
198. Zugel U., Kaufmann S.H. Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin. Microbiol. Rev. 1999, 12:19-39.