Heat shock factors and the control of the stress response

Biochemical Pharmacology

Volumn 59, Issue 1, 2000, Pages 55-63

  Santoro, M Gabriella ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Antiviral; Cyclopentenone; Heat shock factor; Heat shock proteins; Heat shock response; NF B; Prostaglandins

Indexed keywords

CYCLOPENTENONE; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTANOID; TRANSCRIPTION FACTOR;

ANIMAL CELL; CELL PROTECTION; CELL SURVIVAL; EUKARYOTIC CELL; GENE TRANSLOCATION; HEAT SHOCK RESPONSE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRESS;

EID: 0033990336     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00299-3     Document Type: Conference Paper

References (69)

1. Linquist S., Craig E.A. The heat shock proteins. Annu Rev Genet. 22:1988;631-677.
2. Morimoto R.I., Santoro M.G. Stress-inducible responses and heat shock proteins New pharmacologic targets for cytoprotection . Nat Biotechnol. 16:1998;833-838.
3. Feige U., Morimoto R.I., Yahara I., Polla B.S. Stress-Inducible Cellular Responses. 1996;Birkhäuser-Verlag, Basel-Boston-Berlin.
4. Sistonen L., Sarge K.D., Phillips B., Abravaya K., Morimoto R. Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells. Mol Cell Biol. 12:1992;4104-4111.
5. Santoro M.G., Garaci E., Amici C. Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells. Proc Natl Acad Sci USA. 86:1989;8407-8411.
6. Parsell D.A., Lindquist S. Heat shock proteins and stress tolerance. Morimoto R.I., Tissieres A., Georgopoulos C. The Biology of Heat Shock Proteins and Molecular Chaperones. 1994;457-494 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
7. Freeman B.C., Morimoto R.I. The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-I have distinct roles in recognition of a non-native protein and protein refolding. EMBO J. 15:1996;2969-2979.
8. Craig E.A., Baxter B.K., Becker J., Halladay J., Ziegelhoffer. Cytosolic hsp70s of Saccharomyces cerevisiae Roles in protein synthesis, protein translocation, proteolysis, and regulation . Morimoto R.I., Tissieres A., Georgopoulos C. The Biology of Heat Shock Proteins and Molecular Chaperones. 1994;31-52 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
9. Langer T., Neupert W. Chaperoning mitochondrial biogenesis. Morimoto R.I., Tissieres A., Georgopoulos C. The Biology of Heat Shock Proteins and Molecular Chaperones. 1994;53-84 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
10. Wu C. Heat shock transcription factors Structure and regulation . Annu Rev Cell Dev Biol. 11:1995;441-469.
11. Morimoto R.I., Kroeger P.E., Cotto J.J. The transcriptional regulation of heat shock genes A plethora of heat shock factors and regulatory conditions . Feige U., Morimoto R.I., Yahara I., Polla B.S. Stress-Inducible Cellular Responses. 1996;139-163 Birkhäuser-Verlag, Basel-Boston-Berlin.
12. Amin J., Ananthan J., Voellmy R. Key features of heat shock regulatory elements. Mol Cell Biol. 8:1988;3761-3769.
13. Perisic O., Xiao H., Lis J.T. Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit. Cell. 59:1989;797-806.
14. Xiao H., Perisic O., Lis J.T. Cooperative binding of Drosophila heat shock factor to arrays of a conserved 5 bp unit. Cell. 64:1991;585-593.
15. Williams G.T., Morimoto R.I. Maximal stress-induced transcription from the human hsp70 promoter requires interactions with the basal promoter elements independent of rotational alignment. Mol Cell Biol. 10:1990;3125-3136.
16. Rabindran S.K., Giorgi G., Clos J., Wu C. Molecular cloning and expression of a human heat shock factor, HSF1. Proc Natl Acad Sci USA. 88:1991;6906-6910.
17. Sarge K.D., Zimarino V., Holm K., Wu C., Morimoto R.I. Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability. Genes Dev. 5:1991;1902-1911.
18. Schuetz T.J., Gallo G.J., Sheldon L., Tempst P., Kingston R.E. Isolation of a cDNA for HSF2 Evidence for two heat shock factor genes in humans . Proc Natl Acad Sci USA. 88:1991;6911-6915.
19. Nakai A., Morimoto R.I. Characterization of a novel chicken heat shock transcription factor, HSF3, suggests a new regulatory pathway. Mol Cell Biol. 13:1993;1983-1997.
20. Nakai A., Tanabe M., Kawazoe Y., Inazawa J., Morimoto R.I., Nagata K. HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator. Mol Cell Biol. 17:1997;469-481.
21. Harrison C.J., Bohm A.A., Nelson H.C. Crystal structure of the DNA binding domain of the heat shock transcription factor. Science. 264:1994;224-227.
22. Peteranderl R., Nelson H.C. Trimerization of the heat shock transcription factor by a triple-stranded α-helical coiled-coil. Biochemistry. 31:1992;12272-12276.
23. Rabindran S.K., Haroun R.I., Clos J., Wisniewski J., Wu C. Regulation of heat shock factor trimerization Role of a conserved leucine zipper . Science. 259:1993;230-234.
24. Green M., Schuetz T.J., Sullivan E.K., Kingston R.E. A heat shock-responsive domain of human HSF1 that regulates transcription activation domain function. Mol Cell Biol. 15:1995;3354-3362.
25. Voellmy R. Sensing stress and responding to stress. Feige U., Morimoto R.I., Yahara I., Polla B.S. Stress-Inducible Cellular Responses. 1996;121-137 Birkhäuser-Verlag, Basel-Boston-Berlin.
26. Tanabe M., Kawazoe Y., Takeda S., Morimoto R.I., Nagata K., Nakai A. Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and the loss of thermotolerance. EMBO J. 17:1998;1750-1758.
27. Shi Y., Mosser D.D., Morimoto R.I. Molecular chaperones as HSF1-specific transcriptional repressors. Genes Dev. 12:1998;654-666.
28. Lee B.S., Chen J., Angelidis C., Jurivich D.A., Morimoto R.I. Pharmacological modulation of heat shock factor 1 by anti-inflammatory drugs results in protection against stress-induced cellular damage. Proc Natl Acad Sci USA. 92:1995;7207-7211.
29. Amici C., Rossi A., Santoro M.G. Aspirin enhances thermotolerance in human erythroleukemic cells An effect associated with the modulation of the heat shock response . Cancer Res. 55:1995;4452-4457.
30. Cotto J.J., Kline M.P., Morimoto R.I. Activation of heat shock factor I DNA binding precedes stress-induced serine phosphorylation Evidence for a multistep pathway of regulation . J Biol Chem. 271:1996;3355-3358.
31. Elia G., De Marco A., Rossi A., Santoro M.G. Inhibition of hsp70 expression by calcium ionophore A23187 in human cells. An effect independent of the acquisition of DNA-binding activity by the heat shock transcription factor. J Biol Chem. 271:1996;16111-16118.
32. Satyal S., Chen D., Fox S.G., Kramer J.M., Morimoto R.I. Negative regulation of the heat shock transcriptional response by HSBP1. Genes Dev. 12:1998;1962-1974.
33. Williams R.S., Thomas J.A., Fina M., German Z., Benjamin I.J. Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress. J Clin Invest. 92:1993;503-508.
34. Polla B.S., Bachelet M., Elia G., Santoro M.G. Stress proteins in inflammation. Ann N Y Acad Sci. 851:1998;75-85.
35. Amici C., Giorgi C., Rossi A., Santoro M.G. Selective inhibition of virus protein synthesis by prostaglandin A A translational block associated with HSP70 synthesis . J Virol. 68:1994;6890-6899.
36. Mestril R., Chi S.H., Sayen M.R., O'Reilly K., Dillmann W.H. Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against stimulated ischemia-induced injury. J Clin Invest. 93:1994;759-767.
37. Marber M.S., Walker J.M., Latchman D.S., Yellon D.M. Myocardial protection after whole body heat stress in the rabbit is dependent on metabolic substrate and is related to the amount of the inducible 70-kD heat stress protein. J Clin Invest. 93:1994;1087-1094.
38. Plumier J., Ross B.M., Currie R.W., Angelidis C.E., Kazlaris H., Kollias G., Pagoulatos G.N. Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. J Clin Invest. 95:1995;1854-1860.
39. Morris S.D., Cumming D.V., Latchman D.S., Yellon D.M. Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. J Clin Invest. 97:1996;706-712.
40. Vigh L., Literati P.N., Horvath I., Torok Z., Balogh G., Glatz A., Kovacs E., Boros I., Ferdinandy P., Farkas B., Jaszlits L., Jednakovits A., Koranyi L., Maresca B. Bimoclomol A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects . Nat Med. 3:1997;1150-1154.
41. Jaattela M., Wissing D., Bauer P.A., Li G.C. Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. EMBO J. 11:1992;3507-3512.
42. Feinstein D.L., Galea E., Aquino D.A., Li G.C., Xu H., Reis D.J. Heat shock protein 70 suppresses astroglial-inducible nitric-oxide synthase expression by decreasing NF-κB activation. J Biol Chem. 271:1996;17724-17732.
43. Villar J., Edelson J.D., Post M., Brendan J., Mullen M., Slutsky A.S. Induction of heat stress proteins is associated with decreased mortality in an animal model of acute lung injury. Am Rev Respir Dis. 147:1993;177-181.
44. Santoro M.G. Antiviral activity of cyclopentenone prostanoids. Trends Microbiol. 5:1997;276-281.
45. Santoro M.G., Garaci E., Amici C. Induction of HSP70 by prostaglandins. Schlesinger M.J., Santoro M.G., Garaci E. Stress Proteins Induction and Function . 1990;27-44 Springer-Verlag, Berlin.
46. Amici C., Sistonen L., Santoro M.G., Morimoto R.I. Antiproliferative prostaglandins activate heat shock transcription factor. Proc Natl Acad Sci USA. 89:1992;6227-6231.
47. Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. 15-Deoxy-delta 12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 83:1995;803-812.
48. 1 An effect associated with heat shock transcription factor activation . Proc Natl Acad Sci USA. 94:1997;746-750.
49. 1 in human monocytes. Evidence for transcriptional and post-transcriptional regulation. Eur J Biochem. 264:1999;736-745.
50. 2 -anti-tumor and anti-viral activities and the mechanisms involved. Eicosanoids. 3:1990;189-199.
51. Rossi A., Elia G., Santoro M.G. 2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity. J Biol Chem. 271:1996;32192-32196.
52. Amici C., Palamara A.T., Santoro M.G. Induction of thermotolerance by prostaglandin A in human cells. Exp Cell Res. 207:1993;230-234.
53. Jiang C., Ting A.T., Seed B. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature. 391:1998;82-86.
54. Santoro M.G., Benedetto A., Carruba G., Garaci E., Jaffe B.M. Prostaglandin A compounds as antiviral agents. Science. 209:1980;1032-1034.
55. Santoro M.G. Viral infection. Feige U., Morimoto R.I., Yahara I., Polla B.S. Stress-Inducible Cellular Responses. 1996;337-357 Birkhäuser-Verlag, Basel-Boston-Berlin.
56. 2 is regulated at two separate levels and is associated with induction of stress protein synthesis. Antiviral Res. 20:1993;193-208.
57. Rozera C., Carattoli A., De Marco A., Amici C., Giorgi C., Santoro M.G. Inhibition of HIV-1 replication by cyclopentenone prostaglandins in acutely infected human cells. J Clin Invest. 97:1996;1795-1803.
58. De Marco A., Carattoli A., Rozera C., Fortini D., Giorgi C., Belardo G., Amici C., Santoro M.G. Induction of the heat-shock response by antiviral prostaglandins in human cells infected with human immunodeficiency virus type 1. Eur J Biochem. 256:1998;334-341.
59. Nabel G., Baltimore D. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature. 326:1987;711-713.
60. Baldwin A.S. The NF-κB and IκB proteins New discoveries and insights . Annu Rev Immunol. 14:1996;649-683.
61. Barnes P.J., Karin M. Nuclear factor-κB A pivotal transcription factor in chronic inflammatory diseases . N Engl J Med. 336:1997;1066-1071.
62. DiDonato J.A., Hayakawa M., Rothwarf D., Zandi E., Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388:1997;548-554.
63. Delhase M., Hayakawa M., Chen Y., Karin M. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation. Science. 284:1999;309-313.
64. Rothwarf D.M., Zandi E., Natoli G., Karin M. IKK-γ is an essential regulatory subunit of the IκB kinase complex. Nature. 395:1998;297-300.
65. Rossi A., Elia G., Santoro M.G. Activation of the heat shock factor 1 by serine protease inhibitors. An effect associated with nuclear factor-κB inhibition. J Biol Chem. 273:1998;16446-16452.
66. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc Natl Acad Sci USA. 93:1996;9090-9095.
67. Singh S., Aggarwal B.B. Activation of transcription factor NF-κB is suppressed by curcumin (diferulolylmethane). J Biol Chem. 42:1995;24995-25000.
68. Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids Inhibition of NF-kappaB activity through induction of I kappa B synthesis . Science. 270:1995;286-290.
69. Kopp E., Ghosh S. Inhibition of NF-κB by sodium salicylate and aspirin. Science. 265:1994;956-959.