Contrasting effects of HSP72 expression on apoptosis in human umbilical vein endothelial cells and an angiogenic cell line, ECV304

British Journal of Haematology

Volumn 110, Issue 4, 2000, Pages 957-964

  Lucas, M ^a   Rose, P E ^b   Morris, A G ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b WARWICK HOSPITAL   (United Kingdom)

Author keywords

Adenoviral vectors; Apoptosis; Endothelial cells; Heat shock protein 72; Verotoxin

Indexed keywords

BETA GALACTOSIDASE; HEAT SHOCK PROTEIN 72; PROPIDIUM IODIDE; VEROTOXIN;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; STRAIN DIFFERENCE; UMBILICAL VEIN;

ADENOVIRIDAE; APOPTOSIS; CELL LINE; CELLS, CULTURED; CYCLOHEXIMIDE; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC VECTORS; HEAT; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN SYNTHESIS INHIBITORS; SHIGA TOXINS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

EID: 0033754727     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02255.x     Document Type: Article

References (33)

1. Induction of heat shock response leads to apoptosis in endothelial cells previously exposed to endotoxin
2. Heat-shock protein 72 modulates pathways of stress-induced apoptosis
3. Susceptibility of AML cells to in vitro apoptosis correlates with heat shock protein 70 (hsp70) expression
4. Caspases: The executioners of apoptosis
5. Heat shock induces I-kappa B-alpha and prevents stress-induced endothelial cell apoptosis
6. IAP family proteins - Suppressors of apoptosis
7. The consequences of expressing HSP70 in Drosophila cells at normal temperatures
8. Hsp70 prevents activation of stress kinases
9. Role of Hsp70 in regulation of stress-kinase JNK. Implications in apoptosis and aging
10. Increased heat-shock protein-90 (HSP90) expression leads to increased apoptosis in the monoblastoid cell-line U937 following induction with TNF-alpha and cycloheximide - A possible role in immunopathology
11. Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovlrus: Suppression of the immune response with cyclosporin
12. Functional characterisation of the spontaneously transformed human umbilical vein endothelial cell line ECV304: Use in an in vitro model of angiogenesis
13. Escaping cell death: Survival proteins in cancer
14. Major heat shock protein hsp70 protects tumour cells from tumour necrosis factor cytotoxicity
15. HSP70 exerts its anti-apoptotic function downstream of caspase-3-like proteases
16. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
17. The proto-oncogene Bcl-2 and its role in regulating apoptosis
18. Wild-type p53 is a cell cycle checkpoint determinant following irradiation
19. Metabolic oxidative stress-induced hsp70 gene expression is mediated through SAPK pathway
20. Overexpression of the heat shock protein 70 enhances the TCR/CD3- and Fas/Apo-1/CD95-mediated apoptotic cell death in Jurkat T cells
21. Heat-shock proteins HSP90 and HSP70 protect Neuro L cells from thermal-stress but not from programmed cell-death
22. Heat-shock induces apoptosis in mouse thymocytes and protects them from glucocorticoid-induced cell-death
23. Cells in stress: Transcriptional activation of heat shock genes
24. Role of human heat shock protein hsp70 in protection against stress-induced apoptosis
25. Apoptosis by death factor
26. Exploiting retrograde transport of Shiga-like toxin 1 for the delivery of exogenous antigens into the MHC class I presentation pathway
27. The haematology of haemolytic uraemic syndrome
28. Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumour necrosis factor-α: Balance between growth and death signals
29. Spontaneous transformation and immortalisation of human endothelial cells
30. Caspases: Enemies within
31. Induction of human endothelial cell apoptosis requires both heat shock and oxidative stress responses
32. Induction of apoptosis by quercetin: Involvement of heat shock protein
33. Intracellular distribution of HSP70 during long duration moderate hyperthermia