Serum heat shock protein and anti-heat shock protein antibody levels in aging

Experimental Gerontology

Volumn 36, Issue 2, 2001, Pages 341-352

  Rea, I M ^a,c   McNerlan, S ^a   Pockley, A G ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c Tel: +44 1232 272 156 ^*  (United Kingdom)

Author keywords

Aging; Enzyme immunoassay; Heat shock proteins; Serum

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; PROTEIN ANTIBODY;

ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ENZYME IMMUNOASSAY; FEMALE; GROUPS BY AGE; HOMEOSTASIS; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGRESSION ANALYSIS; SAMPLE; SERUM; STRESS;

ADULT; AGED; AGED, 80 AND OVER; AGING; ANTIGEN-ANTIBODY COMPLEX; AUTOANTIBODIES; BACTERIAL PROTEINS; CHAPERONIN 60; CHAPERONINS; FEMALE; HOMEOSTASIS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALE; MIDDLE AGED;

EID: 0035114098     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(00)00215-1     Document Type: Article

References (44)

1. Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis
2. T lymphocyte recognition of hsp60 in experimental arthritis
3. The identification of secreted heat shock 60-like protein from rat glial cells and a human neuroblastoma cell line
4. Heat shock cognate-70 gene expression declines during normal aging of the primate retina
5. Heat shock protein studies in Type 1 and Type 2 diabetes and human islet cell culture
6. Heat shock protein 60 and the regulation of autoimmunity
7. Stress response of senescent T lymphocytes: reduced hsp70 is independent of the proliferative block.
8. Diminished heat-shock protein synthesis following mitogen stimulation of lymphocytes from aged donors
9. Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats
10. Mini Mental State, a practical method for grading the cognitive state of patients for the clinician
11. Age dependence of heat stress mediated cardioprotection
12. Aging reduces adaptive capacity and stress protein expression in the liver after heat stress
13. Expression of heat shock genes in hepatocytes is affected by age and food restriction in rats.
14. Heat shock, stress proteins, chaperones and proteotoxicity
15. Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins.
16. Effect of heat shock proteins on survival of isolated aortic cells from normal and atherosclerotic cynomolgus macaques
17. Exogenous Hsp70 becomes cell associated, but not internalised by stressed arterial smooth muscle cells
18. Role of Hsp60 during autoimmune and bacterial inflammation
19. Soluble oligovalent antigen-antibody complexes II. The effect of various selective forces upon relative stability of isolated complexes
20. Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells
21. Admission criteria for immunogerontological studies in man: the Senieur protocol
22. Attenuated induction of heat shock gene expression in aging diploid fibroblasts
23. Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus
24. Reduction in heat shock gene expression correlates with increased thermosensitivity in senescent human fibroblasts
25. Do serum antibodies to heat-shock protein 65 relate to age or stroke?
26. Heat shock and proinflammatory stressors induce differential localisation of heat shock proteins in human monocytes
27. Anti-modified L.D.L. antibodies and LDL-containing immune complexes in IDDM patients and healthy controls
28. The chaperone function of hsp70 is required for protection against stress-induced apoptosis
29. T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.
30. What turns on heat shock genes?
31. Diminished heat shock protein 70 mRNA induction in aged rats after ischemia
32. The expression of heat shock protein 70 decreases with age in lymphocytes from rats and rhesus monkeys
33. Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals
34. Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals
35. Circulating heat shock protein 60 is associated with early cardiovascular disease
36. T cell subtype recognition of self heat shock protein 60
37. + T cell subsets according to their expression of CD45 isotypes
38. Community-living nonagenarians in Northern Ireland have lower plasma homocysteine but similar methylenetetrahydrofolate reductase thermolabile genotype prevalence compared to 70-89 year old subjects
39. Approach to define normal aging in man: immune function, serum lipids, lipoproteins and neopterin levels
40. Aging and the cellular response to stress: reduction in the heat shock response
41. Soluble oligovalent antigen-antibody complexes. I. The effect of antigen valence and combining ratio on the composition of fluorescein-carrier anti-fluorescein complexes
42. Elevated levels of circulating heat shock protein 70 (Hsp70) in peripheral and renal vascular disease
43. Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population