DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1

Biochemical Pharmacology

Volumn 68, Issue 3, 2004, Pages 523-530

  Lees Murdock, Diane J ^a   Barnett, Yvonne A ^a   Barnett, Christopher R ^b  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Cells; 1 nitrosopiperidine; CYP2E1; cytochrome P450 2E1; Cytotoxicity; dimethylnitrosamine; DMN; DNA damage; HEPES; N 2 hydroxyethylpiperazine N 2 ethanesulfonic acid; N nitrosopyrrolidine; Nitrosamines; NPIP; NPYR; reactive oxygen species; ROS

Indexed keywords

1 NITROPIPERIDINE; COMPLEMENTARY DNA; CYTOCHROME P450 2E1; DIMETHYLNITROSAMINE; FORMALDEHYDE; N NITROSOPYRROLIDINE; NEUTRAL RED; NITROSAMINE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DESTRUCTION; CELL LINE; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; INCUBATION TIME; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CELL SURVIVAL; COMET ASSAY; CYTOCHROME P-450 CYP2E1; DIABETES MELLITUS, TYPE 1; DNA DAMAGE; GENE EXPRESSION; HUMANS; ISLETS OF LANGERHANS; NEUTRAL RED; NITROSAMINES; RATS;

EID: 3042698258     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.04.008     Document Type: Article

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