-
1
-
-
24144472565
-
The burden of mortality attributable to diabetes: Realistic estimates for the year
-
10.2337/diacare.28.9.2130
-
Roglic G Unwin N Bennett PH Mathers C Tuomilehto J Nag S Connolly V King H The burden of mortality attributable to diabetes: Realistic estimates for the year Diabetes Care 2000, 28:2130-2135. 10.2337/diacare.28.9.2130
-
(2000)
Diabetes Care
, vol.28
, pp. 2130-2135
-
-
Roglic, G.1
Unwin, N.2
Bennett, P.H.3
Mathers, C.4
Tuomilehto, J.5
Nag, S.6
Connolly, V.7
King, H.8
-
2
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
10.2337/diacare.27.5.1047 15111519
-
Wild S Roglic G Green A Sicree R King H Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 2004, 27:1047-1053. 10.2337/diacare.27.5.1047 15111519
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
3
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
10.1007/s00125-003-1190-9 12637977
-
Kahn SE The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes Diabetologia 2003, 46:3-19. 10.1007/s00125-003-1190-9 12637977
-
(2003)
Diabetologia
, vol.46
, pp. 3-19
-
-
Kahn, S.E.1
-
4
-
-
41149115561
-
Islet inflammation in type 2 diabetes: From metabolic stress to therapy
-
10.2337/dc08-s243
-
Donath MY Schumann DM Faulenbach M Ellingsgaard H Perren A Ehses JA Islet inflammation in type 2 diabetes: From metabolic stress to therapy Diabetes Care 2008, 31(Suppl 2):161-164. 10.2337/dc08-s243
-
(2008)
Diabetes Care
, vol.31
, Issue.SUPPL. 2
, pp. 161-164
-
-
Donath, M.Y.1
Schumann, D.M.2
Faulenbach, M.3
Ellingsgaard, H.4
Perren, A.5
Ehses, J.A.6
-
5
-
-
34447129009
-
Changing perspectives in diabetes: Their impact on its classification
-
10.1007/s00125-007-0665-5 17457564
-
Wilkin TJ Changing perspectives in diabetes: Their impact on its classification Diabetologia 2007, 50:1587-1592. 10.1007/ s00125-007-0665-5 17457564
-
(2007)
Diabetologia
, vol.50
, pp. 1587-1592
-
-
Wilkin, T.J.1
-
7
-
-
0032898667
-
Fatty acids, lipotoxicity and insulin secretion
-
10.1007/s001250051130 10064091
-
McGarry JD Dobbins RL Fatty acids, lipotoxicity and insulin secretion Diabetologia 1999, 42:128-138. 10.1007/s001250051130 10064091
-
(1999)
Diabetologia
, vol.42
, pp. 128-138
-
-
McGarry, J.D.1
Dobbins, R.L.2
-
8
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
-
10.1210/en.2004-0478 15297438
-
Kharroubi I Ladrière L Cardozo AK Dogusan Z Cnop M Eizirik DL Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress Endocrinology 2004, 145:5087-5096. 10.1210/en.2004-0478 15297438
-
(2004)
Endocrinology
, vol.145
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladrière, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
Eizirik, D.L.6
-
9
-
-
52749087214
-
Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets
-
10.2337/db06-1806 18458149
-
Kato T Shimano H Yamamoto T Ishikawa M Kumadaki S Matsuzaka T Nakagawa Y Yahagi N Nakakuki M Hasty AH Takeuchi Y Kobayashi K Takahashi A Yatoh S Suzuki H Sone H Yamada N Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets Diabetes 2008, 57:2382-2392. 10.2337/db06-1806 18458149
-
(2008)
Diabetes
, vol.57
, pp. 2382-2392
-
-
Kato, T.1
Shimano, H.2
Yamamoto, T.3
Ishikawa, M.4
Kumadaki, S.5
Matsuzaka, T.6
Nakagawa, Y.7
Yahagi, N.8
Nakakuki, M.9
Hasty, A.H.10
Takeuchi, Y.11
Kobayashi, K.12
Takahashi, A.13
Yatoh, S.14
Suzuki, H.15
Sone, H.16
Yamada, N.17
-
10
-
-
0032482988
-
Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression
-
21377 9689119 10.1073/pnas.95.16.9558
-
Shimabukuro M Wang MY Zhou YT Newgard CB Unger RH Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression Proc Natl Acad Sci USA 1998, 95:9558-9561. 21377 9689119 10.1073/pnas.95.16.9558
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9558-9561
-
-
Shimabukuro, M.1
Wang, M.Y.2
Zhou, Y.T.3
Newgard, C.B.4
Unger, R.H.5
-
11
-
-
1542284737
-
Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1
-
10.1007/s00125-003-1293-3 14722646
-
Rakatzi I Mueller H Ritzeler O Tennagels N Eckel J Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1 Diabetologia 2004, 47:249-258. 10.1007/ s00125-003-1293-3 14722646
-
(2004)
Diabetologia
, vol.47
, pp. 249-258
-
-
Rakatzi, I.1
Mueller, H.2
Ritzeler, O.3
Tennagels, N.4
Eckel, J.5
-
12
-
-
39149143637
-
Adipokines: The missing link between insulin resistance and obesity
-
18093861
-
Antuna-Puente B Feve B Fellahi S Bastard JP Adipokines: The missing link between insulin resistance and obesity Diabetes Metab 2008, 34:2-11. 18093861
-
(2008)
Diabetes Metab
, vol.34
, pp. 2-11
-
-
Antuna-Puente, B.1
Feve, B.2
Fellahi, S.3
Bastard, J.P.4
-
13
-
-
33845866857
-
Inflammation and metabolic disorders
-
10.1038/nature05485 17167474
-
Hotamisligil GS Inflammation and metabolic disorders Nature 2006, 444:860-867. 10.1038/nature05485 17167474
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
14
-
-
41649093318
-
Inflammatory mechanisms in the regulation of insulin resistance
-
2215762 18235842 10.2119/2007-00119.Tilg
-
Tilg H Moschen AR Inflammatory mechanisms in the regulation of insulin resistance Mol Med 2008, 14:222-231. 2215762 18235842 10.2119/ 2007-00119.Tilg
-
(2008)
Mol Med
, vol.14
, pp. 222-231
-
-
Tilg, H.1
Moschen, A.R.2
-
15
-
-
1642538431
-
Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats
-
10.1016/j.bbrc.2003.12.180 14741717
-
Masuyama T Komeda K Hara A Noda M Shinohara M Oikawa T Kanazawa Y Taniguchi K Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats Biochem Biophys Res Commun 2004, 314:870-877. 10.1016/j.bbrc.2003.12.180 14741717
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 870-877
-
-
Masuyama, T.1
Komeda, K.2
Hara, A.3
Noda, M.4
Shinohara, M.5
Oikawa, T.6
Kanazawa, Y.7
Taniguchi, K.8
-
16
-
-
33748306069
-
Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat
-
10.2337/db05-1526 16731824
-
Homo-Delarche F Calderari S Irminger JC Gangnerau MN Coulaud J Rickenbach K Dolz M Halban P Portha B Serradas P Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat Diabetes 2006, 55:1625-1633. 10.2337/db05-1526 16731824
-
(2006)
Diabetes
, vol.55
, pp. 1625-1633
-
-
Homo-Delarche, F.1
Calderari, S.2
Irminger, J.C.3
Gangnerau, M.N.4
Coulaud, J.5
Rickenbach, K.6
Dolz, M.7
Halban, P.8
Portha, B.9
Serradas, P.10
-
18
-
-
42449126643
-
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis
-
10.2337/db07-0595 18174526
-
Martinez SC Tanabe K Cras-Méneur C Abumrad NA Bernal-Mizrachi E Permutt MA Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis Diabetes 2008, 57:846-859. 10.2337/db07-0595 18174526
-
(2008)
Diabetes
, vol.57
, pp. 846-859
-
-
Martinez, S.C.1
Tanabe, K.2
Cras-Méneur, C.3
Abumrad, N.A.4
Bernal-Mizrachi, E.5
Permutt, M.A.6
-
19
-
-
0034664960
-
A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein
-
1221302 10970784 10.1042/0264-6021:3500717
-
Versteeg HH Nijhuis E Brink van den GR Evertzen M Pynaert GN van Deventer SJ Coffer PJ Peppelenbosch MP A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein Biochem J 2000, 350:717-722. 1221302 10970784 10.1042/0264-6021:3500717
-
(2000)
Biochem J
, vol.350
, pp. 717-722
-
-
Versteeg, H.H.1
Nijhuis, E.2
Brink, G.R.3
Evertzen, M.4
Pynaert, G.N.5
van Deventer, S.J.6
Coffer, P.J.7
Peppelenbosch, M.P.8
-
21
-
-
34548454113
-
Regulation of interleukin-2 signaling by fatty acids in human lymphocytes
-
10.1194/jlr.M700175-JLR200 17592174
-
Gorjão R Hirabara SM de Lima TM Cury-Boaventura MF Curi R Regulation of interleukin-2 signaling by fatty acids in human lymphocytes J Lipid Res 2007, 48:2009-2019. 10.1194/jlr.M700175-JLR200 17592174
-
(2007)
J Lipid Res
, vol.48
, pp. 2009-2019
-
-
Gorjão, R.1
Hirabara, S.M.2
de Lima, T.M.3
Cury-Boaventura, M.F.4
Curi, R.5
-
23
-
-
0035877087
-
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis
-
10.1016/S0006-2952(01)00605-0 11377386
-
Saldeen J Lee JC Welsh N Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis Biochem Pharmacol 2001, 61:1561-1569. 10.1016/S0006-2952(01)00605-0 11377386
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 1561-1569
-
-
Saldeen, J.1
Lee, J.C.2
Welsh, N.3
-
24
-
-
30044444610
-
Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells
-
1383671 16097952 10.1042/BJ20050814
-
Makeeva N Myers JW Welsh N Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells Biochem J 2006, 393:129-139. 1383671 16097952 10.1042/BJ20050814
-
(2006)
Biochem J
, vol.393
, pp. 129-139
-
-
Makeeva, N.1
Myers, J.W.2
Welsh, N.3
-
25
-
-
47749122129
-
Rosiglitazone counteracts palmitate-induced beta-cell dysfunction by suppression of MAP kinase, inducible nitric oxide synthase and caspase 3 activities
-
10.1007/s00018-008-8100-8 18560759
-
Abaraviciene SM Lundquist I Salehi A Rosiglitazone counteracts palmitate-induced beta-cell dysfunction by suppression of MAP kinase, inducible nitric oxide synthase and caspase 3 activities Cell Mol Life Sci 2008, 65:2256-2265. 10.1007/s00018-008-8100-8 18560759
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2256-2265
-
-
Abaraviciene, S.M.1
Lundquist, I.2
Salehi, A.3
-
26
-
-
0032478314
-
Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes
-
19389 9482914 10.1073/pnas.95.5.2498
-
Shimabukuro M Zhou YT Levi M Unger RH Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes Proc Natl Acad Sci USA 1998, 95:2498-2502. 19389 9482914 10.1073/pnas.95.5.2498
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.T.2
Levi, M.3
Unger, R.H.4
-
27
-
-
48249125013
-
Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms
-
2366067 18478115 10.1371/journal.pone.0002182
-
Meidute Abaraviciene S Lundquist I Galvanovskis J Flodgren E Olde B Salehi A Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms PLoS ONE 2008, 3:e2182. 2366067 18478115 10.1371/journal.pone.0002182
-
(2008)
PLoS ONE
, vol.3
-
-
Meidute Abaraviciene, S.1
Lundquist, I.2
Galvanovskis, J.3
Flodgren, E.4
Olde, B.5
Salehi, A.6
-
28
-
-
33644749322
-
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
10.2337/diabetes.54.suppl_2.S97
-
Cnop M Welsh N Jonas JC Jörns A Lenzen S Eizirik DL Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities Diabetes 2005, 54(Suppl 2):97-107. 10.2337/ diabetes.54.suppl_2.S97
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
, pp. 97-107
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jörns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
29
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
1236697 16200199 10.1172/JCI26373
-
Xu C Bailly-Maitre B Reed JC Endoplasmic reticulum stress: Cell life and death decisions J Clin Invest 2005, 115:2656-2664. 1236697 16200199 10.1172/JCI26373
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
30
-
-
19944432792
-
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells
-
10.2337/diabetes.54.2.452 15677503
-
Cardozo AK Ortis F Storling J Feng YM Rasschaert J Tonnesen M Van Eylen F Mandrup-Poulsen T Herchuelz A Eizirik DL Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells Diabetes 2005, 54:452-461. 10.2337/ diabetes.54.2.452 15677503
-
(2005)
Diabetes
, vol.54
, pp. 452-461
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
Feng, Y.M.4
Rasschaert, J.5
Tonnesen, M.6
Van Eylen, F.7
Mandrup-Poulsen, T.8
Herchuelz, A.9
Eizirik, D.L.10
|