The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity

Molecular and Cellular Endocrinology

Volumn 309, Issue 1-2, 2009, Pages 63-66

  D'Aleo, Valentina ^a   Del Guerra, Silvia ^a   Martano, Manuela ^c   Bonamassa, Barbara ^b   Canistro, Donatella ^b   Soleti, Antonio ^c   Valgimigli, Luca ^d   Paolini, Moreno ^b   Filipponi, Franco ^a   Boggi, Ugo ^a   Del Prato, Stefano ^a   Lupi, Roberto ^a  

^a UNIVERSITY OF PISA   (Italy)

^b Alma Mater Studiorum   (Italy)

^c Medestea Research   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Antioxidants; FFA; Human pancreatic islet; Lipotoxicity; Oxidative stress

Indexed keywords

3 NITROTYROSINE; ANTIOXIDANT; BIS(1 HYDROXY 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL)DECANDIOATE; CATALASE; COLLAGENASE; COPPER ZINC SUPEROXIDE DISMUTASE; FATTY ACID; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; INSULIN; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; OLEIC ACID; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AGED; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; INCUBATION TIME; INSULIN RELEASE; MALE; MOLECULAR WEIGHT; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CATALASE; CELL SURVIVAL; CYTOPROTECTION; FATTY ACIDS; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; GLUCOKINASE; GLUCOSE TRANSPORTER TYPE 2; GLUTATHIONE PEROXIDASE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MOLECULAR WEIGHT; OXIDATIVE STRESS; PEPTIDES; PIPERIDINES; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TYROSINE;

EID: 67749115955     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2009.05.010     Document Type: Article

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