메뉴 건너뛰기




Volumn 13, Issue 3, 2013, Pages 133-144

Effects of tobacco constituents and psychological stress on the beta-adrenergic regulation of non-small cell lung cancer and pancreatic cancer: Implications for intervention

Author keywords

beta adrenergic signaling; cancer intervention; NSCLC; psychological stress; tobacco constituents

Indexed keywords

4 AMINOBUTYRIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; NEUROTRANSMITTER; NICOTINE; NICOTINIC RECEPTOR; PROTEIN P53;

EID: 84881444195     PISSN: 15740153     EISSN: 18758592     Source Type: Journal    
DOI: 10.3233/CBM-130323     Document Type: Article
Times cited : (18)

References (81)
  • 1
    • 42049101034 scopus 로고    scopus 로고
    • Systemic treatment for advanced (stage IIIb/IV) non-small cell lung cancer: More treatment options; More things to consider. Conclusion
    • P.A. Bunn, Jr., N. Thatcher, Systemic treatment for advanced (stage IIIb/IV) non-small cell lung cancer: more treatment options; more things to consider. Conclusion, Oncologist 13 Suppl 1 (2008) 37-46.
    • (2008) Oncologist , vol.13 SUPPL. 1 , pp. 37-46
    • Bunn, J.R.P.A.1    Thatcher, N.2
  • 3
    • 0035889705 scopus 로고    scopus 로고
    • Incidence of lung cancer in a large cohort of non-smoking men from Sweden
    • P. Boffetta, B. Jarvholm, P. Brennan, O. Nyren, Incidence of lung cancer in a large cohort of non-smoking men from Sweden, Int J Cancer 94 (2001) 591-593.
    • (2001) Int J Cancer , vol.94 , pp. 591-593
    • Boffetta, P.1    Jarvholm, B.2    Brennan, P.3    Nyren, O.4
  • 4
    • 25644461068 scopus 로고    scopus 로고
    • International lung cancer trends by histologic type: Male:female differences diminishing and adenocarcinoma rates rising
    • DOI 10.1002/ijc.21183
    • S.S. Devesa, F. Bray, A.P. Vizcaino, D.M. Parkin, International lung cancer trends by histologic type: male: Female differences diminishing and adenocarcinoma rates rising, Int J Cancer 117 (2005) 294-299. (Pubitemid 41379403)
    • (2005) International Journal of Cancer , vol.117 , Issue.2 , pp. 294-299
    • Devesa, S.S.1    Bray, F.2    Vizcaino, A.P.3    Parkin, D.M.4
  • 5
    • 51649086146 scopus 로고    scopus 로고
    • Trends in lung cancer incidence by histological type in osaka, japan
    • Y. Toyoda, T. Nakayama, A. Ioka, H. Tsukuma, Trends in lung cancer incidence by histological type in Osaka, Japan, Jpn J Clin Oncol 38 (2008) 534-539.
    • (2008) Jpn J Clin Oncol , vol.38 , pp. 534-539
    • Toyoda, Y.1    Nakayama, T.2    Ioka, A.3    Tsukuma, H.4
  • 7
    • 80052732697 scopus 로고    scopus 로고
    • Non-small cell lung cancer in never smokers as a representative 'non-smoking-associated lung cancer': Epidemiology and clinical features
    • T. Yano, A. Haro, Y. Shikada, R. Maruyama, Y. Maehara, Non-small cell lung cancer in never smokers as a representative 'non-smoking-associated lung cancer': Epidemiology and clinical features, Int J Clin Oncol 16 (2011) 287-293.
    • (2011) Int J Clin Oncol , vol.16 , pp. 287-293
    • Yano, T.1    Haro, A.2    Shikada, Y.3    Maruyama, R.4    Maehara, Y.5
  • 9
    • 79958033195 scopus 로고    scopus 로고
    • Defining new paradigms for the treatment of pancreatic cancer
    • K. Almhanna, P.A. Philip, Defining new paradigms for the treatment of pancreatic cancer, Curr Treat Options Oncol 12 (2011) 111-125.
    • (2011) Curr Treat Options Oncol , vol.12 , pp. 111-125
    • Almhanna, K.1    Philip, P.A.2
  • 12
    • 33645802000 scopus 로고    scopus 로고
    • The effects of stress and smoking on catecholaminergic and cardiovascular response
    • J.D. Robinson, P.M. Cinciripini, The effects of stress and smoking on catecholaminergic and cardiovascular response, Behav Med 32 (2006) 13-18.
    • (2006) Behav Med , vol.32 , pp. 13-18
    • Robinson, J.D.1    Cinciripini, P.M.2
  • 13
    • 0024470434 scopus 로고
    • Regulation of cell proliferation by β-adrenergic receptors in a human lung adenocarcinoma cell line
    • H.M. Schuller, B. Cole, Regulation of cell proliferation by beta-adrenergic receptors in a human lung adenocarcinoma cell line, Carcinogenesis 10 (1989) 1753-1755. (Pubitemid 19222282)
    • (1989) Carcinogenesis , vol.10 , Issue.9 , pp. 1753-1755
    • Schuller, H.M.1    Cole, B.2
  • 14
    • 0028979841 scopus 로고
    • Betaadrenergic mitogenic signal transduction in peripheral lung adenocarcinoma: Implications for individuals with preexisting chronic lung disease
    • P.G. Park, J. Merryman, M. Orloff, H.M. Schuller, Betaadrenergic mitogenic signal transduction in peripheral lung adenocarcinoma: implications for individuals with preexisting chronic lung disease, Cancer Res 55 (1995) 3504-3508.
    • (1995) Cancer Res , vol.55 , pp. 3504-3508
    • Park, P.G.1    Merryman, J.2    Orloff, M.3    Schuller, H.M.4
  • 15
    • 0035098423 scopus 로고    scopus 로고
    • β-Adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas
    • D.L. Weddle, P. Tithoff, M. Williams, H.M. Schuller, Betaadrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas, Carcinogenesis 22 (2001) 473-479. (Pubitemid 32203828)
    • (2001) Carcinogenesis , vol.22 , Issue.3 , pp. 473-479
    • Weddle, D.L.1    Tithoff, P.2    Williams, M.3    Schuller, H.M.4
  • 16
    • 84857667674 scopus 로고    scopus 로고
    • Social stress promotes and γ- Aminobutyric acid inhibits tumor growth in mouse models of non small cell lung cancer
    • H.A.N. Al-Wadei, H.K. Plummer, 3rd, M.F. Ullah, B. Unger, J. Brody, H.M. Schuller, Social stress promotes and γ- aminobutyric acid inhibits tumor growth in mouse models of non small cell lung cancer, Cancer Prevent Res 5 (2012) 189- 196.
    • (2012) Cancer Prevent Res , vol.5 , pp. 189-196
    • Al-Wadei, H.A.N.1    Plummer, H.K.2    Ullah III, F.M.3    Unger, B.4    Brody, J.5    Schuller, H.M.6
  • 17
    • 84855397364 scopus 로고    scopus 로고
    • 3rd Regulation of pancreatic cancer by neuropsychological stress responses: A novel target for intervention
    • H.M. Schuller, H.A. Al-Wadei, M.F. Ullah, H.K. Plummer, 3rd, Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention, Carcinogenesis 33 (2012) 191-196.
    • Carcinogenesis , vol.33 , Issue.2012 , pp. 191-196
    • Schuller, H.M.1    Al-Wadei, H.A.2    Ullah, M.F.3    Plummer, H.K.4
  • 18
    • 0038391247 scopus 로고    scopus 로고
    • Molecular biology and electrophysiology of neuronal nicotinic receptors of rat chromaffin cells
    • DOI 10.1046/j.1460-9568.2003.02669.x
    • S. Di Angelantonio, C. Matteoni, E. Fabbretti, A. Nistri, Molecular biology and electrophysiology of neuronal nicotinic receptors of rat chromaffin cells, Eur J Neurosci 17 (2003) 2313-2322. (Pubitemid 36793740)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.11 , pp. 2313-2322
    • Di Angelantonio, S.1    Matteoni, C.2    Fabbretti, E.3    Nistri, A.4
  • 19
    • 77953357626 scopus 로고    scopus 로고
    • Chronic exposure to estrogen and the tobacco carcinogen NNK cooperatively modulates nicotinic receptors in small airway epithelial cells
    • H.A. Al-Wadei, M.H. Al-Wadei, T. Masi, H.M. Schuller, Chronic exposure to estrogen and the tobacco carcinogen NNK cooperatively modulates nicotinic receptors in small airway epithelial cells, Lung Cancer 69 (2010) 33-39.
    • (2010) Lung Cancer , vol.69 , pp. 33-39
    • Al-Wadei, H.A.1    Al-Wadei, M.H.2    Masi, T.3    Schuller, H.M.4
  • 20
    • 84857225346 scopus 로고    scopus 로고
    • Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3 alpha5, and alpha7
    • M.H. Al-Wadei, H.A. Al-Wadei, H.M. Schuller, Pancreatic Cancer Cells and Normal Pancreatic Duct Epithelial Cells Express an Autocrine Catecholamine Loop that Is Activated by Nicotinic Acetylcholine Receptors alpha3, alpha5, and alpha7, Mol Cancer Res 10 (2012) 239-249.
    • (2012) Mol Cancer Res , vol.10 , pp. 239-249
    • Al-Wadei, M.H.1    Al-Wadei, H.A.2    Schuller, H.M.3
  • 22
    • 0033568544 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone is a β-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via β-adrenergic receptor-mediated release of arachidonic acid
    • H.M. Schuller, P.K. Tithof, M. Williams, H. Plummer, 3rd, The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via betaadrenergic receptor-mediated release of arachidonic acid, Cancer Res 59 (1999) 4510-4515. (Pubitemid 29428948)
    • (1999) Cancer Research , vol.59 , Issue.18 , pp. 4510-4515
    • Schuller, H.M.1    Tithof, P.K.2    Williams, M.3    Plummer III, H.4
  • 23
    • 0036597698 scopus 로고    scopus 로고
    • Mechanisms of smoking-related lung and pancreatic adenocarcinoma development
    • H.M. Schuller, Mechanisms of smoking-related lung and pancreatic adenocarcinoma development, Nat Rev Cancer 2 (2002) 455-463. (Pubitemid 37328942)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.6 , pp. 455-463
    • Schuller, H.M.1
  • 25
    • 33747450166 scopus 로고    scopus 로고
    • NNK activates ERK1/2 and CREB/ATF-1 via β-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells
    • DOI 10.1002/ijc.21987
    • E. Laag, M. Majidi, M. Cekanova, T. Masi, T. Takahashi, H.M. Schuller, NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells, Int J Cancer 119 (2006) 1547-1552. (Pubitemid 44258759)
    • (2006) International Journal of Cancer , vol.119 , Issue.7 , pp. 1547-1552
    • Laag, E.1    Majidi, M.2    Cekanova, M.3    Masi, T.4    Takahashi, T.5    Schuller, H.M.6
  • 26
    • 34547116879 scopus 로고    scopus 로고
    • Nongenomic β estrogen receptors enhance β1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone in human small airway epithelial cells
    • DOI 10.1158/0008-5472.CAN-07-0483
    • M. Majidi, H.A. Al-Wadei, T. Takahashi, H.M. Schuller, Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells, Cancer Res 67 (2007) 6863- 6871. (Pubitemid 47105533)
    • (2007) Cancer Research , vol.67 , Issue.14 , pp. 6863-6871
    • Majidi, M.1    Al-Wadei, H.A.2    Takahashi, T.3    Schuller, H.M.4
  • 27
    • 27144434360 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone stimulates proliferation of immortalized human pancreatic duct epithelia through β-adrenergic transactivation of EGF receptors
    • DOI 10.1007/s00432-005-0002-7
    • M.D. Askari, M.S. Tsao, H.M. Schuller, The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors, J Cancer Res Clin Oncol 131 (2005) 639-648. (Pubitemid 41502206)
    • (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.10 , pp. 639-648
    • Askari, M.D.F.1    Tsao, M.-S.2    Schuller, H.M.3
  • 28
    • 0033534196 scopus 로고    scopus 로고
    • Evidence for a beta2-adrenergic/arachidonic acid pathway in ventricular cardiomyocytes. Regulation by the beta1-adrenergic/camp pathway
    • C. Pavoine, S. Magne, A. Sauvadet, F. Pecker, Evidence for a beta2-adrenergic/arachidonic acid pathway in ventricular cardiomyocytes. Regulation by the beta1-adrenergic/camp pathway, J Biol Chem 274 (1999) 628-637.
    • (1999) J Biol Chem , vol.274 , pp. 628-637
    • Pavoine, C.1    Magne, S.2    Sauvadet, A.3    Pecker, F.4
  • 29
    • 0031957001 scopus 로고    scopus 로고
    • Norepinephrine stimulates arachidonic acid release from vascular smooth muscle via activation of cPLA2
    • E.F. LaBelle, E. Polyak, Norepinephrine stimulates arachidonic acid release from vascular smooth muscle via activation of cPLA2, Am J Physiol 274 (1998) C1129-1137.
    • (1998) Am J Physiol , vol.274
    • Labelle, E.F.1    Polyak, E.2
  • 30
    • 0033784638 scopus 로고    scopus 로고
    • Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters
    • H.M. Schuller, B. Porter, A. Riechert, Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters, J Cancer Res Clin Oncol 126 (2000) 624-630.
    • (2000) J Cancer Res Clin Oncol , vol.126 , pp. 624-630
    • Schuller, H.M.1    Porter, B.2    Riechert, A.3
  • 31
    • 67249100746 scopus 로고    scopus 로고
    • Prevention of pancreatic cancer by the beta-blocker propranolol
    • H.A. Al-Wadei, M.H. Al-Wadei, H.M. Schuller, Prevention of pancreatic cancer by the beta-blocker propranolol, Anticancer Drugs 20 (2009) 477-482.
    • (2009) Anticancer Drugs , vol.20 , pp. 477-482
    • Al-Wadei, H.A.1    Al-Wadei, M.H.2    Schuller, H.M.3
  • 32
    • 0036033780 scopus 로고    scopus 로고
    • The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK
    • DOI 10.1007/s00432-002-0365-y
    • H.M. Schuller, L. Zhang, D.L. Weddle, A. Castonguay, K. Walker, M.S. Miller, The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogen esis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK, J Cancer Res Clin Oncol 128 (2002) 525-532. (Pubitemid 35244927)
    • (2002) Journal of Cancer Research and Clinical Oncology , vol.128 , Issue.10 , pp. 525-532
    • Schuller, H.1    Zhang, L.2    Weddle, D.3    Castonguay, A.4    Walker, K.5    Miller, M.6
  • 33
    • 0032499397 scopus 로고    scopus 로고
    • Tobacco-specific carcinogenic nitrosamines: Ligands for nicotinic acetylcholine receptors in human lung cancer cells
    • DOI 10.1016/S0006-2952(97)00651-5, PII S0006295297006515
    • H.M. Schuller, M. Orloff, Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells, Biochem Pharmacol 55 (1998) 1377-1384. (Pubitemid 28298517)
    • (1998) Biochemical Pharmacology , vol.55 , Issue.9 , pp. 1377-1384
    • Schuller, H.M.1    Orloff, M.2
  • 34
    • 33748184886 scopus 로고    scopus 로고
    • The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells
    • DOI 10.1007/s00432-006-0113-9
    • J. Arredondo, A.I. Chernyavsky, S.A. Grando, The nicotinic receptor antagonists abolish pathobiologic effects of tobaccoderived nitrosamines on BEP2D cells, J Cancer Res Clin Oncol 132 (2006) 653-663. (Pubitemid 44310331)
    • (2006) Journal of Cancer Research and Clinical Oncology , vol.132 , Issue.10 , pp. 653-663
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 35
    • 33646800564 scopus 로고    scopus 로고
    • Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells
    • J. Arredondo, A.I. Chernyavsky, S.A. Grando, Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells, Cancer Biol Ther 5 (2006) 511-517. (Pubitemid 43765286)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.5 , pp. 511-517
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 36
    • 62349131006 scopus 로고    scopus 로고
    • Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter gamma-aminobutyric acid
    • H.A. Al-Wadei, H.K. Plummer, 3rd, H.M. Schuller, Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter gamma-aminobutyric acid, Carcinogenesis 30 (2009) 506-511.
    • (2009) Carcinogenesis , vol.30 , pp. 506-511
    • Al-Wadei, H.A.1    Plummer, H.K.2    Schuller III, M.H.3
  • 37
    • 34249776345 scopus 로고    scopus 로고
    • Nicotine promotes cell proliferation via α7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells
    • DOI 10.1016/j.taap.2007.04.002, PII S0041008X07001639
    • H.P. Wong, L. Yu, E.K. Lam, E.K. Tai, W.K. Wu, C.H. Cho, Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes- mediated pathway in human colon adenocarcinoma HT- 29 cells, Toxicol Appl Pharmacol 221 (2007) 261-267. (Pubitemid 46855813)
    • (2007) Toxicology and Applied Pharmacology , vol.221 , Issue.3 , pp. 261-267
    • Wong, H.P.S.1    Yu, L.2    Lam, E.K.Y.3    Tai, E.K.K.4    Wu, W.K.K.5    Cho, C.H.6
  • 38
    • 33847316161 scopus 로고    scopus 로고
    • Functional role of β-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells
    • DOI 10.1093/toxsci/kfl118
    • V.Y. Shin, W.K. Wu, K.M. Chu, M.W. Koo, H.P. Wong, E.K. Lam, E.K. Tai, C.H. Cho, Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells, Toxicol Sci 96 (2007) 21-29. (Pubitemid 46323205)
    • (2007) Toxicological Sciences , vol.96 , Issue.1 , pp. 21-29
    • Shin, V.Y.1    Wu, W.K.K.2    Chu, K.M.3    Koo, M.W.L.4    Wong, H.P.S.5    Lam, E.K.Y.6    Tai, E.K.K.7    Cho, C.H.8
  • 39
    • 84881396216 scopus 로고    scopus 로고
    • Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters
    • M.H. Al-Wadei, H.A. Al-Wadei, H.M. Schuller, Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters, Carcinogenesis.
    • Carcinogenesis
    • Al-Wadei, M.H.1    Al-Wadei, H.A.2    Schuller, H.M.3
  • 40
    • 0033771402 scopus 로고    scopus 로고
    • The superfamily of heptahelical receptors
    • R.J. Lefkowitz, The superfamily of heptahelical receptors, Nat Cell Biol 2 (2000) E133-136.
    • (2000) Nat Cell Biol , vol.2
    • Lefkowitz, R.J.1
  • 41
    • 51449108819 scopus 로고    scopus 로고
    • Review. Neurobiology of nicotine dependence
    • A. Markou, Review. Neurobiology of nicotine dependence, Philos Trans R Soc Lond B Biol Sci 363 (2008) 3159-3168.
    • (2008) Philos Trans R Soc Lond B Biol Sci , vol.363 , pp. 3159-3168
    • Markou, A.1
  • 42
    • 60749101452 scopus 로고    scopus 로고
    • Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?
    • H.M. Schuller, Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? Nat Rev Cancer 9 (2009) 195-205.
    • (2009) Nat Rev Cancer , vol.9 , pp. 195-205
    • Schuller, H.M.1
  • 43
    • 53349145473 scopus 로고    scopus 로고
    • Gammaaminobutyric acid a potential tumor suppressor for small airway- derived lung adenocarcinoma
    • H.M. Schuller, H.A. Al-Wadei, M. Majidi, Gammaaminobutyric acid, a potential tumor suppressor for small airway- derived lung adenocarcinoma, Carcinogenesis 29 (2008) 1979-1985.
    • (2008) Carcinogenesis , vol.29 , pp. 1979-1985
    • Schuller, H.M.1    Al-Wadei, H.A.2    Majidi, M.3
  • 44
    • 39049158404 scopus 로고    scopus 로고
    • B receptor is a novel drug target for pancreatic cancer
    • DOI 10.1002/cncr.23231
    • H.M. Schuller, H.A. Al-Wadei, M. Majidi, GABA B receptor is a novel drug target for pancreatic cancer, Cancer 112 (2008) 767-778. (Pubitemid 351240570)
    • (2008) Cancer , vol.112 , Issue.4 , pp. 767-778
    • Schuller, H.M.1    Al-Wadei, H.A.N.2    Majidi, M.3
  • 45
    • 84881432289 scopus 로고    scopus 로고
    • Chronic nicotine and NNK exposure causes promoter hypermethylation of GAD2 in human pancreatic duct epithelial cells
    • Orlando, FL, USA
    • H. Bernert, H.K. Plummer III, H.M. Schuller, Chronic nicotine and NNK exposure causes promoter hypermethylation of GAD2 in human pancreatic duct epithelial cells., AACR 102nd Annual Meeting, vol. 52, Orlando, FL, USA, 2011, p. 3816.
    • (2011) AACR 102nd Annual Meeting , vol.52 , pp. 3816
    • Bernert, H.1    Plummer III, H.K.2    Schuller, H.M.3
  • 46
    • 84856430018 scopus 로고    scopus 로고
    • Gamma-amino butyric acid inhibits the nicotine-imposed stimulatory challenge in xenograft models of non-small cell lung carcinoma
    • H.A. Al-Wadei, M.H. Al-Wadei, M.F. Ullah, H.M. Schuller, Gamma-amino butyric acid inhibits the nicotine-imposed stimulatory challenge in xenograft models of non-small cell lung carcinoma, Curr Cancer Drug Targets 12 (2012) 97-106.
    • (2012) Curr Cancer Drug Targets , vol.12 , pp. 97-106
    • Al-Wadei, H.A.1    Al-Wadei, M.H.2    Ullah, M.F.3    Schuller, H.M.4
  • 48
    • 33644507072 scopus 로고    scopus 로고
    • Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells
    • M. Sato, M.B. Vaughan, L. Girard, M. Peyton, W. Lee, D.S. Shames, R.D. Ramirez, N. Sunaga, A.F. Gazdar, J.W. Shay, J.D. Minna, Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells, Cancer Res 66 (2006) 2116-2128.
    • (2006) Cancer Res , vol.66 , pp. 2116-2128
    • Sato, M.1    Vaughan, M.B.2    Girard, L.3    Peyton, M.4    Lee, W.5    Shames, D.S.6    Ramirez, R.D.7    Sunaga, N.8    Gazdar, A.F.9    Shay, J.W.10    Minna, J.D.11
  • 49
    • 70450231632 scopus 로고    scopus 로고
    • Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G (i) proteins in cardiomyocytes
    • R. Liu, B. Ramani, D. Soto, V. De Arcangelis, Y. Xiang, Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G(i) proteins in cardiomyocytes, J Biol Chem 284 (2009) 32279-32287.
    • (2009) J Biol Chem , vol.284 , pp. 32279-32287
    • Liu, R.1    Ramani, B.2    Soto, D.3    De Arcangelis, V.4    Xiang, Y.5
  • 50
    • 38749132961 scopus 로고    scopus 로고
    • Long-term behavioral and neuroendocrine alterations following chronic social stress inmice: Implications for stress-related disorders
    • V. Sterlemann, K. Ganea, C. Liebl, D. Harbich, S. Alam, F. Holsboer, M.B. Muller, M.V. Schmidt, Long-term behavioral and neuroendocrine alterations following chronic social stress inmice: implications for stress-related disorders, Horm Behav 53 (2008) 386-394.
    • (2008) Horm Behav , vol.53 , pp. 386-394
    • Sterlemann, V.1    Ganea, K.2    Liebl, C.3    Harbich, D.4    Alam, S.5    Holsboer, F.6    Muller, M.B.7    Schmidt, M.V.8
  • 51
    • 0034672410 scopus 로고    scopus 로고
    • The neurobiology of stress: From serendipity to clinical relevance
    • B.S. McEwen, The neurobiology of stress: from serendipity to clinical relevance, Brain Res 886 (2000) 172-189.
    • (2000) Brain Res , vol.886 , pp. 172-189
    • McEwen, B.S.1
  • 52
    • 84865097981 scopus 로고    scopus 로고
    • Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer om vitro and in xenograft models of stress-free and stress-exposed mice
    • in press
    • H.A. Al-Wadei, M.H. Al.-wadei, M.F. Ullah, H.M. Schuller, Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer om vitro and in xenograft models of stress-free and stress-exposed mice., Plos One (in press) (2012).
    • (2012) Plos One
    • Al-Wadei, H.A.1    Al.-Wadei, M.H.2    Ullah, M.F.3    Schuller, H.M.4
  • 53
    • 84860543431 scopus 로고    scopus 로고
    • Norepinephrine stimulates pancreatic cancer cell proliferation, migration and invasion via beta-adrenergic receptor-dependent activation of P38/MAPK pathway
    • X.Y. Huang, H.C. Wang, Z. Yuan, J. Huang, Q. Zheng, Norepinephrine stimulates pancreatic cancer cell proliferation, migration and invasion via beta-adrenergic receptor-dependent activation of P38/MAPK pathway, Hepatogastroenterology 59 (2012) 889-893.
    • (2012) Hepatogastroenterology , vol.59 , pp. 889-893
    • Huang, X.Y.1    Wang, H.C.2    Yuan, Z.3    Huang, J.4    Zheng, Q.5
  • 54
    • 80955180176 scopus 로고    scopus 로고
    • Beta2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction
    • T. Shan, Q. Ma, D. Zhang, K. Guo, H. Liu, F. Wang, E. Wu, beta2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction, Eur J Pharmacol 665 (2011) 1-7.
    • (2011) Eur J Pharmacol , vol.665 , pp. 1-7
    • Shan, T.1    Ma, Q.2    Zhang, D.3    Guo, K.4    Liu, H.5    Wang, F.6    Wu, E.7
  • 55
    • 59849086623 scopus 로고    scopus 로고
    • Psychological distress and cancer mortality
    • M. Hamer, Y. Chida, G.J. Molloy, Psychological distress and cancer mortality, J Psychosom Res 66 (2009) 255-258.
    • (2009) J Psychosom Res , vol.66 , pp. 255-258
    • Hamer, M.1    Chida, Y.2    Molloy, G.J.3
  • 56
    • 0035137135 scopus 로고    scopus 로고
    • The prevalence of psychological distress by cancer site
    • DOI 10.1002/1099-1611(200101/02)10:1 <19::AID-PON501>3.0.CO;2-6
    • J. Zabora, K. BrintzenhofeSzoc, B. Curbow, C. Hooker, S. Piantadosi, The prevalence of psychological distress by cancer site, Psychooncology 10 (2001) 19-28. (Pubitemid 32106774)
    • (2001) Psycho-Oncology , vol.10 , Issue.1 , pp. 19-28
    • Zabora, J.1    Brintzenhofeszoc, K.2    Curbow, B.3    Hooker, C.4    Piantadosi, S.5
  • 57
    • 26844456493 scopus 로고    scopus 로고
    • Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines
    • H.K. Plummer, 3rd, M.S. Dhar, M. Cekanova, H.M. Schuller, Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines, BMC Cancer 5 (2005) 104.
    • (2005) BMC Cancer , vol.5 , pp. 104
    • Plummer, H.K.1    Dhar III, S.M.2    Cekanova, M.3    Schuller, H.M.4
  • 58
    • 0031740825 scopus 로고    scopus 로고
    • Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors
    • DOI 10.1016/S0006-2952(98)00260-3, PII S0006295298002603
    • S.H. Shafer, S.H. Phelps, C.L. Williams, Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors, Biochem Pharmacol 56 (1998) 1229-1236. (Pubitemid 28511247)
    • (1998) Biochemical Pharmacology , vol.56 , Issue.9 , pp. 1229-1236
    • Shafer, S.H.1    Phelps, S.H.2    Williams, C.L.3
  • 59
    • 0023237775 scopus 로고
    • Cyclic AMP and cyclic GMP phosphodiesterase activities in Hodgkin's disease lymphocytes
    • DOI 10.1016/0192-0561(87)90119-6
    • A. Aleksijevic, C. Lugnier, C. Giron, S. Mayer, J.C. Stoclet, J.M. Lang, Cyclic AMP and cyclic GMP phosphodiesterase activities in Hodgkin's disease lymphocytes, Int J Immunopharmacol 9 (1987) 525-531. (Pubitemid 17101937)
    • (1987) International Journal of Immunopharmacology , vol.9 , Issue.5 , pp. 525-531
    • Aleksijevic, A.1    Lugnier, C.2    Giron, C.3
  • 60
    • 2942604370 scopus 로고    scopus 로고
    • Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: Implications for chemoprevention in smokers
    • DOI 10.1016/j.lungcan.2003.12.007, PII S0169500203006366
    • H.M. Schuller, B. Porter, A. Riechert, K. Walker, R. Schmoyer, Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers, Lung Cancer 45 (2004) 11-18. (Pubitemid 38757827)
    • (2004) Lung Cancer , vol.45 , Issue.1 , pp. 11-18
    • Schuller, H.M.1    Porter, B.2    Riechert, A.3    Walker, K.4    Schmoyer, R.5
  • 61
    • 67649435477 scopus 로고    scopus 로고
    • Non-genomic inhibitory signaling of beta-carotene in squamous cell carcinoma of the lungs
    • H.A. Al-Wadei, H.M. Schuller, Non-genomic inhibitory signaling of beta-carotene in squamous cell carcinoma of the lungs, Int J Oncol 34 (2009) 1093-1098.
    • (2009) Int J Oncol , vol.34 , pp. 1093-1098
    • Al-Wadei, H.A.1    Schuller, H.M.2
  • 62
    • 84863577910 scopus 로고    scopus 로고
    • Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin
    • F. Song, A.A. Qureshi, J. Han, Increased caffeine intake is associated with reduced risk of Basal cell carcinoma of the skin, Cancer Res 72 (2012) 3282-3289.
    • (2012) Cancer Res , vol.72 , pp. 3282-3289
    • Song, F.1    Qureshi, A.A.2    Han, J.3
  • 63
    • 79953227738 scopus 로고    scopus 로고
    • Improving postoperative immune status and resistance to cancer metastasis: A combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses
    • Y. Goldfarb, L. Sorski, M. Benish, B. Levi, R. Melamed, S. Ben-Eliyahu, Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses, Ann Surg 253 (2011) 798-810.
    • (2011) Ann Surg , vol.253 , pp. 798-810
    • Goldfarb, Y.1    Sorski, L.2    Benish, M.3    Levi, B.4    Melamed, R.5    Ben-Eliyahu, S.6
  • 64
    • 84862616765 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and lung cancer: Common pathogenesis, shared clinical challenges
    • B.R. Celli, Chronic obstructive pulmonary disease and lung cancer: common pathogenesis, shared clinical challenges, Proc Am Thorac Soc 9 (2012) 74-79.
    • (2012) Proc Am Thorac Soc , vol.9 , pp. 74-79
    • Celli, B.R.1
  • 66
    • 0027219992 scopus 로고
    • Beta-blocking agents with vasodilator activity
    • C. Rosendorff, Beta-blocking agents with vasodilator activity, J Hypertens Suppl 11 (1993) S37-40. (Pubitemid 23226737)
    • (1993) Journal of Hypertension , vol.11 , Issue.SUPPL. 4
    • Rosendorff, C.1
  • 67
    • 0025879188 scopus 로고
    • Acute and chronic hemodynamic effects of drugs with different actions on adrenergic receptors: A comparison between alpha blockers and different types of beta blockers with and without vasodilating effect
    • P. Lund-Johansen, P. Omvik, Acute and chronic hemodynamic effects of drugs with different actions on adrenergic receptors: a comparison between alpha blockers and different types of beta blockers with and without vasodilating effect, Cardiovasc Drugs Ther 5 (1991) 605-615.
    • (1991) Cardiovasc Drugs Ther , vol.5 , pp. 605-615
    • Lund-Johansen, P.1    Omvik, P.2
  • 68
    • 84860486206 scopus 로고    scopus 로고
    • Is alpha7- nAChR a possible target for lung cancer and malignant pleural mesothelioma treatment?
    • A. Cesario, P. Russo, C. Nastrucci, P. Granone, Is alpha7- nAChR a possible target for lung cancer and malignant pleural mesothelioma treatment?, Curr Drug Targets 13 (2012) 688- 694.
    • (2012) Curr Drug Targets , vol.13 , pp. 688-694
    • Cesario, A.1    Russo, P.2    Nastrucci, C.3    Granone, P.4
  • 70
    • 0037112519 scopus 로고    scopus 로고
    • The neurotransmitter γ-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells
    • J. Joseph, B. Niggemann, K.S. Zaenker, F. Entschladen, The neurotransmitter gamma-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells, Cancer Res 62 (2002) 6467-6469. (Pubitemid 35364108)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6467-6469
    • Joseph, J.1    Niggemann, B.2    Zaenker, K.S.3    Entschladen, F.4
  • 71
    • 0038499447 scopus 로고    scopus 로고
    • Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells
    • DOI 10.1023/A:1024491219366
    • T.L.t. Drell, J. Joseph, K. Lang, B. Niggemann, K.S. Zaenker, F. Entschladen, Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells, Breast Cancer Res Treat 80 (2003) 63-70. (Pubitemid 36851285)
    • (2003) Breast Cancer Research and Treatment , vol.80 , Issue.1 , pp. 63-70
    • Drell IV, T.L.1    Joseph, J.2    Lang, K.3    Niggemann, B.4    Zaenker, K.S.5    Entschladen, F.6
  • 74
    • 0035300538 scopus 로고    scopus 로고
    • Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by β-blockers
    • K. Masur, B. Niggemann, K.S. Zanker, F. Entschladen, Norepinephrine- induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers, Cancer Res 61 (2001) 2866-2869. (Pubitemid 32691927)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 2866-2869
    • Masur, K.1    Niggemann, B.2    Zanker, K.S.3    Entschladen, F.4
  • 76
    • 33646371479 scopus 로고    scopus 로고
    • The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by β-blockers
    • DOI 10.1002/ijc.21723
    • D. Palm, K. Lang, B. Niggemann, T.L.t. Drell, K. Masur, K.S. Zaenker, F. Entschladen, The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers, Int J Cancer 118 (2006) 2744-2749. (Pubitemid 43673352)
    • (2006) International Journal of Cancer , vol.118 , Issue.11 , pp. 2744-2749
    • Palm, D.1    Lang, K.2    Niggemann, B.3    Drell IV, T.L.4    Masur, K.5    Zaenker, K.S.6    Entschladen, F.7
  • 77
    • 79953658412 scopus 로고    scopus 로고
    • Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival
    • D.G. Powe, M.J. Voss, K.S. Zanker, H.O. Habashy, A.R. Green, I.O. Ellis, F. Entschladen, Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival, Oncotarget 1 (2010) 628-638.
    • (2010) Oncotarget , vol.1 , pp. 628-638
    • Powe, D.G.1    Voss, M.J.2    Zanker, K.S.3    Habashy, H.O.4    Green, A.R.5    Ellis, I.O.6    Entschladen, F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.