Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors

Biochemical Pharmacology

Volumn 56, Issue 9, 1998, Pages 1229-1236

  Shafer, Shulamith H ^a   Phelps, Scott H ^a   Williams, Carol L ^a  

^a GUTHRIE RESEARCH INSTITUTE   (United States)

Author keywords

Cell death; Cyclic AMP; Methylxanthines; Phosphodiesterases; Small cell lung carcinoma; Viability

Indexed keywords

CAFFEINE; CALCIUM ION; CYCLIC AMP; CYCLIC AMP PHOSPHODIESTERASE; FURA 2; ISOBUTYLMETHYLXANTHINE; PHOSPHODIESTERASE INHIBITOR; THEOPHYLLINE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; PRIORITY JOURNAL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; CAFFEINE; CALCIUM; CARCINOMA, SMALL CELL; CELL SURVIVAL; CYCLIC AMP; DNA; HUMANS; LUNG NEOPLASMS; PHOSPHODIESTERASE INHIBITORS; THYMIDINE; TUMOR CELLS, CULTURED;

EID: 0031740825     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00260-3     Document Type: Article

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