Chronic exposure to estrogen and the tobacco carcinogen NNK cooperatively modulates nicotinic receptors in small airway epithelial cells

Lung Cancer

Volumn 69, Issue 1, 2010, Pages 33-39

  Al Wadei, Hussein A N ^a,b,c   Al Wadei, Mohammed H ^a,c   Masi, Thomas ^a   Schuller, Hildegard M ^a,c  

^a UNIVERSITY OF TENNESSEE   (United States)

^b SANA A UNIVERSITY   (Yemen)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Estrogen; GABA; Nicotinic acetylcholine receptor; NNK; Noradrenaline; Small airway epithelial cell

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4 AMINOBUTYRIC ACID; ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; ESTROGEN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4; NORADRENALIN; SMALL INTERFERING RNA; 4-(N-METHYL-N-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE; CARCINOGEN; CHRNA7 PROTEIN, HUMAN; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4 SUBUNIT; NITROSAMINE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; SMOKING; UPREGULATION; DRUG EFFECTS; DRUG POTENTIATION; EPITHELIUM CELL; FEMALE; LUNG TUMOR; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SECRETION (PROCESS); SMALL CELL LUNG CANCER; TOXICITY;

CARCINOGENS; DRUG SYNERGISM; EPITHELIAL CELLS; ESTROGENS; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; LUNG NEOPLASMS; NITROSAMINES; NOREPINEPHRINE; RECEPTOR CROSS-TALK; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION; SMALL CELL LUNG CARCINOMA; SMOKING; UP-REGULATION; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR;

EID: 77953357626     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.09.011     Document Type: Article

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