Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Al Wadei, Hussein A N ^a,b   Al Wadei, Mohammed H ^a   Ullah, Mohammad F ^a   Schuller, Hildegard M ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b SANA A UNIVERSITY   (Yemen)

Author keywords

[No Author keywords available]

Indexed keywords

4 5 LIPOXYGENASE; 4 AMINOBUTYRIC ACID; ADRENALIN; ARACHIDONATE 5 LIPOXYGENASE; CELECOXIB; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTRANSMITTER; PROSTAGLANDIN E2; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER PREVENTION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; IMMUNOASSAY; IN VITRO STUDY; IN VIVO STUDY; MALE; MONOTHERAPY; MOUSE; NONHUMAN; ONCOGENE K RAS; PANCREAS CANCER; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SOCIAL STRESS; STRESS; TREATMENT RESPONSE; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; CELL MOVEMENT; CELL PROLIFERATION; CYCLIC AMP; CYCLOOXYGENASE 2; DINOPROSTONE; EPINEPHRINE; GAMMA-AMINOBUTYRIC ACID; HUMANS; IMMUNOASSAY; MALE; MICE; MICE, NUDE; PANCREATIC NEOPLASMS; PYRAZOLES; STRESS, PHYSIOLOGICAL; SULFONAMIDES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865097981     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043376     Document Type: Article

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